Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.
Asai, A; Aihara, E; Watson, C; Mourya, R; Mizuochi, T; Shivakumar, P; Phelan, K; Mayhew, C; Helmrath, M; Takebe, T; et al.
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Preferential TNF alpha signaling via TNFR2 regulates epithelial injury and duct obstruction in experimental biliary atresia.
Shivakumar, P; Mizuochi, T; Mourya, R; Gutta, S; Yang, L; Luo, Z; Bezerra, JA.
JCI insight.
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Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents.
Luo, Z; Shivakumar, P; Mourya, R; Gutta, S; Bezerra, JA.
Gastroenterology.
2019;
157:1138-1152.e14.
Visualizing structures in confocal microscopy datasets through clusterization: A case study on bile ducts.
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Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion.
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PLoS ONE.
2019;
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Regulation of epithelial injury and bile duct obstruction by NLRP3, IL-1R1 in experimental biliary atresia.
Yang, L; Mizuochi, T; Shivakumar, P; Mourya, R; Luo, Z; Gutta, S; Bezerra, JA.
Journal of Hepatology.
2018;
69:1136-1144.
A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.
Huang, W; Rainbow, DB; Wu, Y; Adams, D; Shivakumar, P; Kottyan, L; Karns, R; Aronow, B; Bezerra, J; Gershwin, ME; et al.
Journal of immunology (Baltimore, Md. : 1950).
2018;
200:147-162.
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.
Lertudomphonwanit, C; Mourya, R; Fei, L; Zhang, Y; Gutta, S; Yang, L; Bove, KE; Shivakumar, P; Bezerra, JA.
Science Translational Medicine.
2017;
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Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
Jee, J; Mourya, R; Shivakumar, P; Fei, L; Wagner, M; Bezerra, JA.
PLoS ONE.
2017;
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Hepatic Natural Killer T-Cell and CD8+ T-Cell Signatures in Mice with Nonalcoholic Steatohepatitis.
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Hepatology Communications.
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