A photo of Shannon Standridge.

Shannon M. Standridge, DO, MPH

  • Director, Rett Syndrome Clinic
  • Epilepsy Specialist, Division of Neurology
  • Assistant Professor, UC Department of Pediatrics
When I see patients, I thoroughly listen to their concerns. I answer their questions with care and transparency. During each visit, from the moment we start until we finish, the family and the patient have all my attention.
Shannon M. Standridge, DO, MPH



As a pediatric neurologist, I focus on listening to my patients and their caregivers. I practice with a “whole person” approach rather than a single organ system approach.

When I see patients, I thoroughly listen to their concerns. I answer their questions with care and transparency. During each visit, from the moment we start until we finish, the family and the patient have all my attention.

To ensure that I’m providing the most advanced care, I stay updated on the literature. I strive to bring the most current information into the way I practice.

I specialize in caring for children with refractory epilepsy, Rett syndrome and related conditions. I’m honored that the Rett Syndrome and Related Spectrum Disorders Clinic at Cincinnati Children’s is recognized as a Research Center of Excellence by RettSyndrome.org.

I was always drawn to medicine and pediatrics. My interest in pediatric neurology developed through my work with outstanding clinicians, including Dr. Warren Lo and Dr. Suja Ann Joseph. They convinced me that neurology was the right specialty for me.

As a specialist in Rett syndrome and related disorders, I work on several different studies evaluating the safety and efficacy of different treatment drugs. I also serve on a Rett consortium that continuously works to provide science-based guidelines and current care and management approaches. We also publish manuscripts about what we learn from the scientific data in our natural history study findings.

Here are some fun facts about me: I competed in the Hawaii World Ironman Championship. I carried the Olympic Torch for the U.S. Winter Olympics in 2002. My favorite pastimes include hiking and biking outdoors with family and renovating houses.

Fellowship: Neurophysiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2008; Neurology, Nationwide Children's Hospital, Columbus, OH, 2007.

Residency: Pediatrics, Nationwide Children's Hospital, Columbus, OH, 2004.

MPH: The Ohio State University College of Public Health, Columbus, OH, 2008.

DO: Kansas City University of Medicine and Biosciences, Kansas City, MO, 2002.

BS: Biology, Lyon College, Batesville, AS, 1997.


General neurology

Services and Specialties

Neurology, Epilepsy, Rett Syndrome

Research Areas


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Anxiety-like behavior and anxiolytic treatment in the Rett syndrome natural history study. Buchanan, CB; Stallworth, JL; Joy, AE; Dixon, RE; Scott, AE; Beisang, AA; Benke, TA; Glaze, DG; Haas, RH; Heydemann, PT; et al. Journal of Neurodevelopmental Disorders. 2022; 14:31.

Analysis of X-inactivation status in a Rett syndrome natural history study cohort. Fang, X; Butler, KM; Abidi, F; Gass, J; Beisang, A; Feyma, T; Ryther, RC; Standridge, S; Heydemann, P; Jones, M; et al. Molecular Genetics and Genomic Medicine. 2022; 10:e1917.

Anthropometric Measures Correspond with Functional Motor Outcomes in Females with Rett Syndrome. Motil, KJ; Geerts, S; Annese, F; Neul, JL; Benke, T; Marsh, E; Lieberman, D; Skinner, SA; Glaze, DG; Heydemann, P; et al. The Journal of Pediatrics. 2022; 244:169-177.e3.

Lethal Pediatric Cerebral Vasculitis Triggered by Severe Acute Respiratory Syndrome Coronavirus 2. Poisson, KE; Zygmunt, A; Leino, D; Fuller, CE; Jones, BV; Haslam, D; Staat, MA; Clay, G; Ting, TV; Wesselkamper, K; et al. Pediatric Neurology. 2022; 127:1-5.

Features of Menstruation and Menstruation Management in Individuals with Rett Syndrome. Humphrey, KN; Horn, PS; Olshavsky, L; Reebals, L; Standridge, SM. Journal of Pediatric and Adolescent Gynecology. 2021; 34:144-153.

Rett Syndrome: A Timely Review From Recognition to Current Clinical Approaches and Clinical Study Updates. Ivy, AS; Standridge, SM. Seminars in Pediatric Neurology. 2021; 37:100881.

Multisite Study of Evoked Potentials in Rett Syndrome. Saby, JN; Benke, TA; Peters, SU; Standridge, SM; Matsuzaki, J; Cutri-French, C; Swanson, LC; Lieberman, DN; Key, AP; Percy, AK; et al. Annals of Neurology. 2021; 89:790-802.

Well-woman care and HPV vaccination rates in women with Rett syndrome. Humphrey, KN; Horn, PS; Olshavsky, L; Reebals, L; Standridge, SM. Disability and Health Journal. 2021; 14:100982.

A Psychometric Evaluation of the Motor-Behavioral Assessment Scale for Use as an Outcome Measure in Rett Syndrome Clinical Trials. Raspa, M; Bann, CM; Gwaltney, A; Benke, TA; Fu, C; Glaze, DG; Haas, R; Heydemann, P; Jones, M; Kaufmann, WE; et al. American Journal on Intellectual and Developmental Disabilities. 2020; 125:493-509.

Consensus guidelines on managing Rett syndrome across the lifespan. Fu, C; Armstrong, D; Marsh, E; Lieberman, D; Motil, K; Witt, R; Standridge, S; Nues, P; Lane, J; Dinkel, T; et al. BMJ Paediatrics Open. 2020; 4:e000717.

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