Effective hematopoietic stem cell-based gene therapy in a murine model of hereditary pulmonary alveolar proteinosis.
Hetzel, M; Lopez-Rodriguez, E; Mucci, A; Ha Nguyen, AH; Suzuki, T; Shima, K; Buchegger, T; Dettmer, S; Rodt, T; Bankstahl, JP; et al.
Haematologica.
2020;
105:1147-1157.
Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation. Mechanistic Implications for Desquamative Interstitial Pneumonitis.
Suzuki, T; McCarthy, C; Carey, BC; Borchers, M; Beck, D; Wikenheiser-Brokamp, KA; Black, D; Chalk, C; Trapnell, BC.
American Journal of Respiratory Cell and Molecular Biology.
2020;
62:87-94.
Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra-/- Mice.
Arumugam, P; Suzuki, T; Shima, K; McCarthy, C; Sallese, A; Wessendarp, M; Ma, Y; Meyer, J; Black, D; Chalk, C; et al.
Molecular Therapy.
2019;
27:1597-1611.
Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis.
McCarthy, C; Lee, E; Bridges, JP; Sallese, A; Suzuki, T; Woods, JC; Bartholmai, BJ; Wang, T; Chalk, C; Carey, BC; et al.
Nature Communications.
2018;
9.
iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice.
Mucci, A; Lopez-Rodriguez, E; Hetzel, M; Liu, S; Suzuki, T; Happle, C; Ackermann, M; Kempf, H; Hillje, R; Kunkiel, J; et al.
Stem Cell Reports.
2018;
11:696-710.
Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.
Happle, C; Lachmann, N; Ackermann, M; Mirenska, A; Gohring, G; Thomay, K; Mucci, A; Hetzel, M; Glomb, T; Suzuki, T; et al.
American Journal of Respiratory and Critical Care Medicine.
2018;
198:350-360.
IFN-β Improves Sepsis-related Alveolar Macrophage Dysfunction and Postseptic Acute Respiratory Distress Syndrome-related Mortality.
Hiruma, T; Tsuyuzaki, H; Uchida, K; Trapnell, BC; Yamamura, Y; Kusakabe, Y; Totsu, T; Suzuki, T; Morita, S; Doi, K; et al.
American Journal of Respiratory Cell and Molecular Biology.
2018;
59:45-55.
Targeting cholesterol homeostasis in lung diseases.
Sallese, A; Suzuki, T; McCarthy, C; Bridges, J; Filuta, A; Arumugam, P; Shima, K; Ma, Y; Wessendarp, M; Black, D; et al.
Scientific Reports.
2017;
7.
Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency.
Hetzel, M; Suzuki, T; Hashtchin, AR; Arumugam, P; Carey, B; Schwabbauer, M; Kuhn, A; Meyer, J; Schambach, A; Van Der Loo, J; et al.
Human gene therapy methods.
2017;
28:318-329.
Inhibition of IRAK1 Ubiquitination Determines Glucocorticoid Sensitivity for TLR9-Induced Inflammation in Macrophages.
Kong, F; Liu, Z; Jain, VG; Shima, K; Suzuki, T; Muglia, LJ; Starczynowski, DT; Pasare, C; Bhattacharyya, S.
Journal of Immunology.
2017;
199:3654-3667.