Inflammation, Infection and Venous Thromboembolism.
Colling, ME; Tourdot, BE; Kanthi, Y.
Circulation Research.
2021;
128:2017-2036.
Antisense oligonucleotides and nucleic acids generate hypersensitive platelets.
Zaslavsky, A; Adams, M; Cao, X; Yamaguchi, A; Henderson, J; Busch-Østergren, P; Udager, A; Pitchiaya, S; Tourdot, B; Kasputis, T; et al.
Thrombosis Research.
2021;
200:64-71.
Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1.
Perry, SC; Horn, T; Tourdot, BE; Yamaguchi, A; Kalyanaraman, C; Conrad, WS; Akinkugbe, O; Holinstat, M; Jacobson, MP; Holman, TR.
Biochemistry.
2020;
59:4118-4130.
15-Lipoxygenase-1 biosynthesis of 7S,14S-diHDHA implicates 15-lipoxygenase-2 in biosynthesis of resolvin D5.
Perry, SC; Kalyanaraman, C; Tourdot, BE; Conrad, WS; Akinkugbe, O; Freedman, JC; Holinstat, M; Jacobson, MP; Holman, TR.
Journal of Lipid Research.
2020;
61:1087-1103.
Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators.
Freedman, J; Tran, A; Tourdot, BE; Kalyanaraman, C; Perry, S; Holinstat, M; Jacobson, MP; Holman, TR.
Biochemistry.
2020;
59:1832-1844.
Ectonucleotidase tri(di)phosphohydrolase-1 (ENTPD-1) disrupts inflammasome/interleukin 1β-driven venous thrombosis.
Yadav, V; Chi, L; Zhao, R; Tourdot, BE; Yalavarthi, S; Jacobs, BN; Banka, A; Liao, H; Koonse, S; Anyanwu, AC; et al.
Journal of Clinical Investigation.
2019;
129:2872-2877.
5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.
Green, AR; Freedman, C; Tena, J; Tourdot, BE; Liu, B; Holinstat, M; Holman, TR.
Biochemistry.
2018;
57:6726-6734.
Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics.
Tourdot, BE; Stoveken, H; Trumbo, D; Yeung, J; Kanthi, Y; Edelstein, LC; Bray, PF; Tall, GG; Holinstat, M.
Arteriosclerosis, Thrombosis, and Vascular Biology.
2018;
38:1632-1643.
Targeting 12-Lipoxygenase as a Potential Novel Antiplatelet Therapy.
Tourdot, BE; Holinstat, M.
Trends in Pharmacological Sciences.
2017;
38:1006-1015.
First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.
Adili, R; Tourdot, BE; Mast, K; Yeung, J; Freedman, JC; Green, A; Luci, DK; Jadhav, A; Simeonov, A; Maloney, DJ; et al.
Arteriosclerosis, Thrombosis, and Vascular Biology.
2017;
37:1828-1839.