Durgesh Tiwari

Durgesh Tiwari, PhD


  • Member, Division of Neurology
  • Assistant Professor, UC Department of Pediatrics

About

MPharm: Dept. of Pharmacy, S.G.S.I.T.S, RGPV University, Indore, India, 2009.

PhD: Monash Inst. of Pharm Sciences, Monash University, Melbourne, Australia, 2015.

Pod doc: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2020.

Interests

Neuroscience; molecular biology; cell biology

Research Areas

Neurology

Publications

Mir324 knockout regulates the structure of dendritic spines and impairs hippocampal long-term potentiation. Parkins, EV; Brager, DH; Rymer, JK; Burwinkel, JM; Rojas, D; Tiwari, D; Hu, YC; Gross, C. Scientific Reports. 2023; 13:21919.

MiR-324-5p inhibition after intrahippocampal kainic acid-induced status epilepticus does not prevent epileptogenesis in mice. McGann, AM; Westerkamp, GC; Chalasani, A; Danzer, CS K; Parkins, EV; Rajathi, V; Horn, PS; Pedapati, EV; Tiwari, D; Danzer, SC; Gross, C. Frontiers in Neurology. 2023; 14:1280606.

MicroRNA-218 instructs proper assembly of hippocampal networks. Taylor, SR; Kobayashi, M; Vilella, A; Tiwari, D; Zolboot, N; Du, JX; Spencer, KR; Hartzell, A; Girgiss, C; Abaci, YT; Gross, C; Zoli, M; Berg, DK; Lippi, G. eLife. 2023; 12.

Age-Dependent Regulation of Dendritic Spine Density and Protein Expression in Mir324 KO Mice. Parkins, EV; Burwinkel, JM; Ranatunga, R; Yaser, S; Hu, YC; Tiwari, D; Gross, C. Journal of Molecular Neuroscience. 2023; 73:818-830.

Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice. Tiwari, D; Rajathi, V; Rymer, JK; Beasley, LN; McGann, AM; Bunk, AT; Parkins, EV; Rice, MF; Smith, KE; Ritter, DM; White, AR; Doerning, CM; Gross, C. eNeuro. 2023; 10.

GABAA Alpha 2,3 Modulation Improves Select Phenotypes in a Mouse Model of Fragile X Syndrome. Schaefer, TL; Ashworth, AA; Tiwari, D; Tomasek, MP; Parkins, EV; White, AR; Snider, A; Davenport, MH; Grainger, LM; Becker, RA; Gibson, JR; Huber, KM; Gross, C; Erickson, CA. Frontiers in Psychiatry. 2021; 12:678090.

mTOR-driven neural circuit changes initiate an epileptogenic cascade. LaSarge, CL; Pun, RY K; Gu, Z; Riccetti, MR; Namboodiri, DV; Tiwari, D; Gross, C; Danzer, SC. Progress in Neurobiology. 2021; 200:101974.

The potassium channel Kv4.2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice. Tiwari, D; Schaefer, TL; Schroeder-Carter, LM; Krzeski, JC; Bunk, AT; Parkins, EV; Snider, A; Danzer, R; Williams, MT; Vorhees, CV; Danzer, SC; Gross, C. Experimental Neurology. 2020; 334:113437.

PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes. White, AR; Tiwari, D; MacLeod, MC; Danzer, SC; Gross, C. Neurobiology of Disease. 2020; 144:105026.

Violet-light suppression of thermogenesis by opsin 5 hypothalamic neurons. Zhang, KX; D'Souza, S; Upton, BA; Kernodle, S; Vemaraju, S; Nayak, G; Gaitonde, KD; Holt, AL; Linne, CD; Smith, AN; Sweeney, A; Sanchez-Gurmaches, J; Seeley, RJ; Lang, RA. Nature. 2020; 585:420-425.