Brian M. Varisco, MD

Clinician Researcher, Division of Critical Care Medicine

Academic Affiliations

Associate Professor, UC Department of Pediatrics

Phone 513-803-2485


Lung development; lung fibroblast biology; chronic lung disease / bronchopulmonary dysplasia.

Visit the Varisco Lab.

MD: Medical College of Georgia, Augusta, GA, 2004.

Residency: Pediatrics, The Children's Hospital, Denver, CO.

Fellowship: Pediatrics, The Children's Hospital, Denver, CO.

Certification: Pediatrics, 2008; Pediatric Critical Care Medicine, 2011.

View PubMed Publications

Joshi R, Heinz A, Fan Q, Guo S, Monia B, Schmelzer CE, Weiss A, Batie M, Parameshwaran H, Varisco BM. Role for Cela1 in Postnatal Lung Remodeling and AAT-Deficient Emphysema. American Journal of Respiratory Cell and Molecular Biology. 2018.

Varisco BM, Sbragia L, Chen J, Scorletti F, Joshi R, Wong HR, Lobes-Figueira R, Oria M, Peiro J. Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of Congenital Diaphragmatic Hernia. Molecular Medicine. 2016 Jul 19;22.

Joshi R, Liu S, Brown MD, Young SM, Batie M, Kofron JM, Xu Y, Weaver TE, Apsley K, Varisco BM. Stretch Regulates Expression and binding of Chymotrypsin-like Elastase 1 in the Postnatal Lung. FASEB Journal. 2016 Feb;30(2):590-600.

Young SM, Liu S, Joshi R, Batie M, Kofron M, Jinbang G, Woods J, Varisco BM. Localization and Stretch-Dependence of Lung Elastase Activity in Development and Compensatory Growth. Journal of Applied Physiology (1985). 2015 Apr;118(7):921-31.

Liu S, Cimprich J, Varisco BM. Mouse Pneumonectomy Model of Compensatory Lung Growth. Journal of Visualized Experiments. 2014 Dec 17;(94).

Chamberlain A, Varisco BM. The Pharmacology of Acute Respiratory Distress Syndrome. Clinical Pharmacy and Biopharmaceutics. 2014.

Liu S, Young SM, Varisco BM. Dynamic Expression of Chymotrypsin Like Elastase-1 Over the Course of Lung Development. American Journal of Lung Cell and Molecular Physiology. 2014 Jun 15;306(12):L1104-16.

Liu S, Parameswaran H, Young SM, Varisco BM. JNK Suppresses Pulmonary Fibroblast Elastogenesis During Alveolar Development. Respiratory Research. 2014 Mar 25;15:34.

Cornett B, Snowball J, Varisco BM, Lang R, Whitsett J, Sinner D. Wntless Is Required for Peripheral Lung Differentiation And Pulmonary Vascular Development. Developmental Biology. 2013 Jul 1;379(1):38-52.

Varisco BM, Ambalavanan N, Whitsett JA, Hagood JS. Thy-1 Signals through PPARγ to Promote Lipofibroblast Differentiation in the Developing Lung. Am J Resp Cell Mol Biol. 2012 Jun;46(6):765-72.