I love positively impacting the lives of critically ill children and their families. I began my research career in developmental pulmonary biology hoping to improve baseline lung health in patients with conditions like bronchopulmonary dysplasia (BPD).
Chronic respiratory diseases predispose patients to repeated hospital and intensive care unit (ICU) admissions during acute infections. This problem led to my three primary research interests: understanding acute lung injury in pediatric acute respiratory distress syndrome; understanding the key mechanotransductive signals impacting late prenatal and postnatal lung development; and understanding the mechanisms of progressive airspace destruction in emphysema with a focus on mechanosensitive matrix remodeling.
By identifying key drivers of lung development, injury and repair, I hope to develop targeted therapies to improve lung health in patients with both acute and chronic lung conditions.
For my research work I have been awarded the Parker B. Francis Fellowship; the Society of Critical Care Medicine Discovery Award; and K12, K08 and R01 grants from the National Institutes of Health.
Clinical and translational research requires the participation of patients and their families. As such, I thank them for helping us as we work to advance the care of children.
Associate Professor, UC Department of Pediatrics
Pediatric Intensive Care Unit PICU
Critical Care, Pulmonary Biology