A photo of Derek Wheeler.

Chief of Staff

Associate Chair, Clinical Affairs

Member, Division of Critical Care Medicine

Professor, UC Department of Pediatrics



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My Biography & Research

Research Interests

Stress preconditioning; the innate immune response in critical illness; vascular biology of sepsis; acute kidney injury sepsis; acute lung injury; quality improvement and patient safety 

Academic Affiliation

Professor, UC Department of Pediatrics


Pediatric Intensive Care Unit PICU, Critical Care, Best Doctors, Hospital Medicine

My Locations

My Education

MD: Indiana University School of Medicine, Indianapolis, IN, 1994.

Intern: Department of Pediatrics, Naval Medical Center, San Diego, CA, 1994-1995.

Residency: Department of Pediatrics, Naval Medical Center, San Diego, CA, 1995-1997.

Fellowship: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2000-2003.

Certification: Diplomate, National Board of Medical Examiners, 1995; Diplomate, American Board of Pediatrics, 1997, 2004; Diplomate, American Board of Pediatrics: Sub-Board of Pediatric Critical Care Medicine, 2004.

Masters of Medical Management: Carnegie Mellon University, Pittsburgh, PA, 2013.

MBA: Carl H. Lindner College of Business at the University of Cincinnati, with Post-Graduate Certificate in Health Care Finance, Cincinnati, OH, 2016.

My Publications

Wheeler DS, Dunsmore KE, Denenberg AG, Muething L, Poynter SE, Wong HR. Biological activity of truncated C-terminus human heat shock protein 72. Immunol Lett. 2011 Mar 30;135(1-2):173-9

Mack EH, Wheeler DS, Hirsch R. Endovascular treatment of near-fatal neonatal superior vena cava syndrome. Pediatr Crit Care Med. 2010 Nov 24.

Basu RK, Devarajan P, Wong H, Wheeler DS. An update and review of acute kidney injury in pediatrics. Pediatr Crit Care Med. 2010 Nov 4.

Wong HR, Wheeler DS, Tegtmeyer K, Poynter SE, Kaplan JM, Chima RS, Stalets E, Basu RK, Doughty LA. Toward a clinically feasible gene expression-based subclassification strategy for septic shock: proof of concept. Crit Care Med. 2010 Oct;38(10):1955-61.

Istaphanous GK, Wheeler DS, Lisco SJ, Shander A. Red blood cell transfusion in critically ill children: A narrative review. Pediatr Crit Care Med. 2010 May 6.

Nowak JE, Wheeler DS, Harmon KK, Wong HR. Admission chemokine (C-C motif) ligand 4 levels predict survival in pediatric septic shock. Pediatr Crit Care Med. 2010 Mar;11(2):213-6.

Klein JA, Nowak JE, Sutherell JS, Wheeler DS. Nonsurgical management of cardiac missiles. Pediatr Emerg Care. 2010 Jan;26(1):36-8.

Wheeler DS, Chase MA, Senft AP, Poynter SE, Wong HR, Page K. Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4. Respir Res. 2009 Apr 30;10:31.

Wheeler DS. Death to sepsis: targeting apoptosis pathways in sepsis. Crit Care. 2009;13(6):1010.

Mack EH, Wheeler DS, Embi PJ. Clinical decision support systems in the pediatric intensive care unit. Pediatr Crit Care Med. 2009 Jan;10(1):23-8. Review.