Photo of { Gang Wu, PhD}

Gang Wu, PhD


  • Co-Director of the Bioinformatics, Genetics and Genomics Diagnostic Laboratory, Division of Human Genetics
  • Assistant Professor, UC Department of Pediatrics

About

Postdoctoral Training: Bioinformatics and System Biology, University of Pennsylvania, Cincinnati Children's Hospital Medical Center

PhD: Genomics, University of Chinese Academy of Sciences, China, 2012

BS: Biotechnology, Ocean University of China, China, 2007

Interests

Genetics

Services and Specialties

Interests

Human genomics; biomedical informatics; data science

Research Areas

Publications

Expanding Access to Genome Sequencing: Higher Diagnostic Yield in Self-Referred Participants From the CincyKidsSeq Study and Implications for Hybrid Models of Genetic Service Delivery. Theobald, K; Shillington, A; Jackson, F; Lopes, J; Brewer, CJ; Dawson, B; Wu, G; Denton, J; Pauciulo, M; Zhang, X; Slavotinek, A. Clinical Genetics. 2026; 109(4):717-724.

P521: A systematic evaluation of structured electric health record for rare genetic disease detection. Yu, X; Lu, P; Varney, A; Thiemann, C; Wu, G; Dawson, B; Mendonca, E; Weaver, KN; Chen, J. Genetics in Medicine Open. 2026; 4:104013.

P509: Redefining access and interpretation in genomic medicine: A hybrid model with systematic variant resolution. Theobald, K; Coconaugher, B; Jackson, F; Brewer, C; Dawson, B; Denton, J; Wu, G; Slavotinek, A. Genetics in Medicine Open. 2026; 4:104001.

Mutations of the circadian clock genes Cry, Per, or Bmal1 have different effects on the transcribed and nontranscribed strands of cycling genes. Yang, Y; Wu, G; Sancar, A; Hogenesch, JB. Proceedings of the National Academy of Sciences of the United States of America. 2024; 121(8):e2316731121.

Tumor circadian clock strength influences metastatic potential and predicts patient prognosis in luminal A breast cancer. Li, S-Y; Hammarlund, JA; Wu, G; Lian, J-W; Howell, SJ; Clarke, RB; Adamson, AD; Gonçalves, CF; Hogenesch, JB; Anafi, RC; Meng, Q-J. Proceedings of the National Academy of Sciences of the United States of America. 2024; 121(7):e2311854121.

The circadian clock is disrupted in pancreatic cancer. Schwartz, PB; Nukaya, M; Berres, ME; Rubinstein, CD; Wu, G; Hogenesch, JB; Bradfield, CA; Ronnekleiv-Kelly, SM. PLoS Genetics. 2023; 19(6):e1010770.

0010 Circadian dysregulation of the cardiopulmonary system in a mouse model of obstructive sleep apnea. Koritala, B; Lee, YY; Gaspar, LS; Smith, J; Paulose, J; Francey, L; Wu, G; Ruben, M; Smith, D. Sleep. 2023; 46(Supplement_1):a5-a5.

Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expression. Koritala, BSC; Lee, YY; Gaspar, LS; Bhadri, SS; Su, W; Wu, G; Francey, LJ; Ruben, MD; Gong, MC; Hogenesch, JB; Smith, DF. PLoS Biology. 2023; 21(5):e3002139.

Integration of genome-scale data identifies candidate sleep regulators. Lee, YY; Endale, M; Wu, G; Ruben, MD; Francey, LJ; Morris, AR; Choo, NY; Anafi, RC; Smith, DF; Liu, AC; Hogenesch, JB. Sleep. 2023; 46(2).

Ontogeny and function of the circadian clock in intestinal organoids. Rosselot, AE; Park, M; Kim, M; Matsu-Ura, T; Wu, G; Flores, DE; Subramanian, KR; Lee, S; Sundaram, N; Broda, TR; Wells, JM; Hogenesch, JB; Moore, SR; Hong, CI. EMBO Journal. 2022; 41(2):e106973.