Ting Wen, MD, PhD, has characterized the unique, tissue-specific transcriptome of purified murine eosinophils under homeostasis and allergic conditions and demonstrated the expression and function of a couple of unexpected molecules, CD22 and CAR4, on gastrointestinal and lung eosinophils, respectively (Wen et al., 2012 and 2014, Journal of Immunology).
Dr. Wen also developed a murine eosinophil transfer model system that has proven to be useful in assessing the function of a gene of interest that is expressed on eosinophils or target tissue (Wen et al., 2013, PNAS).
Dr. Wen is a co-inventor of the EoE Diagnostic Panel (EDP), created in part due to his expertise in molecular biopsy and bioinformatics. The Cincinnati Children's-owned patent is now licensed to the diagnostic company Diagnovus, LLC, as Engauge GI-EoE test and is in use in clinical practice (Wen et al., 2013, Gastroenterology).
In the past three years, Dr. Wen won the following awards for his eosinophil-related studies:
- 2011, Fellow-In-Training Travel Award, American Academy of Allergy, Asthma, and Immunology (AAAAI)
- 2013 Outstanding Poster Presentation, 2nd Place, Imaging and Cytometry Research Symposium, Ohio River Valley Cytometry Association (ORVCA)
- 2014 Outstanding Poster Presentation, 1st Place, Imaging and Cytometry Research Symposium, Ohio River Valley Cytometry Association (ORVCA
Dr. Wen has also been an invited speaker on several national and international meetings related to eosinophilic disorders and co-authored to two book chapters.
Assistant Professor, UC Department of Pediatrics
Allergy and Immunology, Eosinophilic Disorders