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Member, Division of Experimental Hematology & Cancer Biology
Assistant Professor, UC Department of Pediatrics
Mei Xin received her PhD from the University of Texas Southwestern Medical Center at Dallas. She completed her postdoctoral training in Eric Olson’s laboratory where she investigated microRNAs and Hippo signaling molecules regulating cardiovascular development and regeneration. In August 2013, Dr. Xin moved to Cincinnati Children’s Hospital Medical Center to study organogenesis including cardiovascular and peripheral nervous system development and diseases.
Regulation of organogenesis such as cardiovascular and heart growth and regeneration, and the nervous system development
Experimental Hematology and Cancer Biology, Cancer and Blood Diseases
MS: Robert Wood Johnson Medical School,
PhD: The University of Texas Southwestern Medical
Center, Dallas, TX.
Fellowship: The University of Texas
Southwestern Medical Center, Dallas, TX.
Yap1-Scribble polarization is required for hematopoietic stem cell division and fate.
Althoff, MJ; Nayak, RC; Hegde, S; Wellendorf, AM; Bohan, B; Filippi, MD; Xin, M; Richard Lu, Q; Geiger, H; Zheng, Y; et al.
miR-143 Regulates Lysosomal Enzyme Transport across the Blood-Brain Barrier and Transforms CNS Treatment for Mucopolysaccharidosis Type I.
Lin, Y; Wang, X; Rose, KP; Dai, M; Han, J; Xin, M; Pan, D.
EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways.
Wang, J; Yang, L; Dong, C; Wang, J; Xu, L; Qiu, Y; Weng, Q; Zhao, C; Xin, M; Lu, QR.
Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Zhang, L; He, X; Liu, X; Zhang, F; Huang, LF; Potter, AS; Xu, L; Zhou, W; Zheng, T; Luo, Z; et al.
Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis.
Weng, Q; Wang, J; Wang, J; He, D; Cheng, Z; Zhang, F; Verma, R; Xu, L; Dong, X; Liao, Y; et al.
Cell Stem Cell.
Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair.
Zhao, C; Dong, C; Frah, M; Deng, Y; Marie, C; Zhang, F; Xu, L; Ma, Z; Dong, X; Lin, Y; et al.
A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration.
He, X; Zhang, L; Queme, LF; Liu, X; Lu, A; Waclaw, RR; Dong, X; Zhou, W; Kidd, G; Yoon, S; et al.
Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.
Wu, LM N; Deng, Y; Wang, J; Zhao, C; Wang, J; Rao, R; Xu, L; Zhou, W; Choi, K; Rizvi, TA; et al.
Transcriptional Regulator ZEB2 Is Essential for Bergmann Glia Development.
He, L; Yu, K; Lu, F; Wang, J; Wu, LN; Zhao, C; Li, Q; Zhou, X; Liu, H; Mu, D; et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance.
Liu, M; Zhang, Z; Sampson, L; Zhou, X; Nalapareddy, K; Feng, Y; Akunuru, S; Melendez, J; Davis, AK; Bi, F; et al.
Stem Cell Reports.
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