A photo of Amanda Zacharias.

Amanda L. Zacharias, PhD


  • Assistant Professor, UC Department of Pediatrics

About

BS: Biomedical Engineering, Northwestern University, Evanston, IL, 2003.

PhD: Cell & Developmental Biology, University of Michigan, Ann Arbor, MI, 2009.

Postdoctoral Fellow: University of Pennsylvania, Philadelphia, PA, 2011-2018.

Interests

Developmental gene regulation; transcriptional enhancers; Wnt signaling; Caenorhabditis elegans

Research Areas

Developmental Biology

Publications

pop-1/TCF, ref-2/ZIC and T-box factors regulate the development of anterior cells in the C. elegans embryo. Rumley, JD; Preston, EA; Cook, D; Peng, FL; Zacharias, AL; Wu, L; Jileaeva, I; Murray, JI. Developmental Biology. 2022; 489:34-46.

The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo. Murray, JI; Preston, E; Crawford, JP; Rumley, JD; Amom, P; Anderson, BD; Sivaramakrishnan, P; Patel, SD; Bennett, BA; Lavon, TD; et al. PLoS Genetics. 2022; 18:e1010187.

De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo. Fang, H; Yao, S; Chen, Q; Liu, C; Cai, Y; Geng, S; Bai, Y; Tian, Z; Zacharias, AL; Takebe, T; et al. ACS Nano. 2019; 13:14426-14436.