Wenying Zhang, MD, PhD, MBA, FACMG

Director, Genetics and Genomics Diagnostic Laboratory, Division of Human Genetics
Associate Professor, UC Department of Pediatrics

wenying.zhang@cchmc.org

About

MD, MS: Peking University Health Science Center, Beijing, China.

PhD: Rutgers University, New Brunswick, NJ.

Fellowship: Clinical Molecular Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certification: American Board of Medical Genetics in Clinical Molecular Genetics, 2011; American Board of Medical Genetics in Labratory of Genetics and Genomics, 2021.

Interests

Clinical molecular genetics; whole exome sequencing; molecular genetic diagnosis of hereditary cardiovascular diseases, genetic blood disorders, and other genetic conditions

Services and Specialties

Genetics and Genomics Diagnostic Laboratory

Research Areas

Human Genetics

Publications

Novel chymotrypsin C (ctrc) variants from real-life genetic testing of pediatric pancreatitis cases. Stefanovics, R; Sandor, M; Sahin-Toth, V; Nemeth, BC; Zhang, W; Abu-El-Haija, M; Sahin-Toth, M. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2024; 24:e16.

Detection of a novel gross deletion in the UNC13D gene ends the diagnostic odyssey for a family with familial hemophagocytic lymphohistiocytosis 3. Nagaraj, CB; Brightman, DS; Rea, H; Wakefield, E; Harkavy, NV G; Dyer, L; Zhang, W. BMC Pediatrics. 2024; 24:34.

Loss of ATG5 in Humans Causes Syndromic Congenital Dyserythropoietic Anemia with Impaired Mitophagy in Late Stages of Terminal Erythropoiesis. Ntoumaziou, A; Nguyen, D; Elgammal, Y; Husami, A; Zhang, W; Weaver, KD; Kasten, JL; Grier, DD; Zheng, Y; Lutzko, C; Risinger, M; Frayne, J; Seu, K; Kalfa, TA. Blood. 2024; 144:1084.

Genetic Testing in Patients with Autoimmune Lymphoproliferative Syndrome: Experience of 802 Patients at Cincinnati Children's Hospital Medical Center. Xu, X; Denton, J; Wu, Y; Liu, J; Guan, Q; Dawson, DB; Bleesing, J; Zhang, W. Journal of Clinical Immunology. 2024; 44:166.

The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children. Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, DS; Farrell, P; Nasr, A; Ibrahim, S; Bellin, MD; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. Clinical Gastroenterology and Hepatology. 2024; 22:2033-2043.e2.

Novel chymotrypsin C (CTRC) variants from real-world genetic testing of pediatric chronic pancreatitis cases. Stefanovics, R; Sándor, M; Demcsák, A; Berke, G; Németh, BC; Zhang, W; Abu-El-Haija, M; Sahin-Tóth, M. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2024; 24:690-697.

Case report: Childhood erythrocytosis due to hypermanganesemia caused by homozygous SLC30A10 mutation. Coppola, T; Hughes, H; Finch, PT; Hess, JA; Wu, S; Prada, CE; Miethke, AG; Zhang, W; Kalfa, TA. 2024; 3:1331485.

Recommendations for risk allele evidence curation, classification, and reporting from the ClinGen Low Penetrance/Risk Allele Working Group. Schmidt, RJ; Steeves, M; Bayrak-Toydemir, P; Benson, KA; Coe, BP; Conlin, LK; Ganapathi, M; Garcia, J; Gollob, MH; Jobanputra, V; Niu, N; Richards, S; Chen, W; Fan, Y. Genetics in Medicine. 2024; 26:101036.

Erythrocyte Disorders Mimicking Congenital Dyserythropoietic Anemia Based on Bone Marrow Pathology Exposed By Genetic Evaluation. Ceolan, J; Seu, K; Ntoumaziou, A; Elgammal, Y; Emberesh, S; Bilston, L; Richards, D; Dickerson, KE; Chonat, S; Rydz, N; Lutzko, C; Husami, A; Zhang, W; Kalfa, TA. Blood. 2023; 142:2459.

Congenital Dyserythropoietic Anemia Type II: An Update from the Congenital Dyseryhtropoietic Anemia Registry of North America (CDAR). Elgammal, Y; Risinger, M; Husami, A; Walden, J; Gupta, S; Shah, NC; Boyer, J; Abajas, YL; Winstead, M; Miller, DW; Lorsbach, R; Zhang, W; Kalfa, TA; Niss, O. Blood. 2023; 142:1079.