Wenying Zhang, MD, PhD, MBA, FACMG

Director, Genetics and Genomics Diagnostic Laboratory, Division of Human Genetics
Associate Professor, UC Department of Pediatrics

wenying.zhang@cchmc.org

About

MD, MS: Peking University Health Science Center, Beijing, China.

PhD: Rutgers University, New Brunswick, NJ.

Fellowship: Clinical Molecular Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certification: American Board of Medical Genetics in Clinical Molecular Genetics, 2011; American Board of Medical Genetics in Labratory of Genetics and Genomics, 2021.

Interests

Clinical molecular genetics; whole exome sequencing; molecular genetic diagnosis of hereditary cardiovascular diseases, genetic blood disorders, and other genetic conditions

Services and Specialties

Genetics and Genomics Diagnostic Laboratory

Research Areas

Human Genetics

Publications

Clinical, Immunologic, and Genetic Characteristics in Patients With Syndrome of Undifferentiated Recurrent Fevers. Macaraeg, M; Baker, E; Handorf, E; Matt, M; Brunner, H; Grom, AA; Henrickson, M; Huggins, J; Zhang, W; Lee, P; Marsh, R; Schulert, GS. Arthritis and Rheumatology. 2025; 77:596-605.

Novel chymotrypsin C (ctrc) variants from real-life genetic testing of pediatric pancreatitis cases. Stefanovics, R; Sandor, M; Sahin-Toth, V; Nemeth, BC; Zhang, W; Abu-El-Haija, M; Sahin-Toth, M. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2024; 24:e16.

Detection of a novel gross deletion in the UNC13D gene ends the diagnostic odyssey for a family with familial hemophagocytic lymphohistiocytosis 3. Nagaraj, CB; Brightman, DS; Rea, H; Wakefield, E; Harkavy, NV G; Dyer, L; Zhang, W. BMC Pediatrics. 2024; 24:34.

Loss of ATG5 in Humans Causes Syndromic Congenital Dyserythropoietic Anemia with Impaired Mitophagy in Late Stages of Terminal Erythropoiesis. Ntoumaziou, A; Nguyen, D; Elgammal, Y; Husami, A; Zhang, W; Weaver, KD; Kasten, JL; Grier, DD; Zheng, Y; Lutzko, C; Risinger, M; Frayne, J; Seu, K; Kalfa, TA. Blood. 2024; 144:1084.

Genetic Testing in Patients with Autoimmune Lymphoproliferative Syndrome: Experience of 802 Patients at Cincinnati Children's Hospital Medical Center. Xu, X; Denton, J; Wu, Y; Liu, J; Guan, Q; Dawson, DB; Bleesing, J; Zhang, W. Journal of Clinical Immunology. 2024; 44:166.

The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children. Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, DS; Farrell, P; Nasr, A; Ibrahim, S; Bellin, MD; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. Clinical Gastroenterology and Hepatology. 2024; 22:2033-2043.e2.

Novel chymotrypsin C (CTRC) variants from real-world genetic testing of pediatric chronic pancreatitis cases. Stefanovics, R; Sándor, M; Demcsák, A; Berke, G; Németh, BC; Zhang, W; Abu-El-Haija, M; Sahin-Tóth, M. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2024; 24:690-697.

Case report: Childhood erythrocytosis due to hypermanganesemia caused by homozygous SLC30A10 mutation. Coppola, T; Hughes, H; Finch, PT; Hess, JA; Wu, S; Prada, CE; Miethke, AG; Zhang, W; Kalfa, TA. Frontiers in Hematology. 2024; 3:1331485.

Recommendations for risk allele evidence curation, classification, and reporting from the ClinGen Low Penetrance/Risk Allele Working Group. Schmidt, RJ; Steeves, M; Bayrak-Toydemir, P; Benson, KA; Coe, BP; Conlin, LK; Ganapathi, M; Garcia, J; Gollob, MH; Jobanputra, V; Niu, N; Richards, S; Chen, W; Fan, Y. Genetics in Medicine. 2024; 26:101036.

Erythrocyte Disorders Mimicking Congenital Dyserythropoietic Anemia Based on Bone Marrow Pathology Exposed By Genetic Evaluation. Ceolan, J; Seu, K; Ntoumaziou, A; Elgammal, Y; Emberesh, S; Bilston, L; Richards, D; Dickerson, KE; Chonat, S; Rydz, N; Lutzko, C; Husami, A; Zhang, W; Kalfa, TA. Blood. 2023; 142:2459.