Headache

Clinical

Headaches; migraines; neurogenetics; neurometabolic disorders

Research

Epidemiology; diagnostic criteria; treatment evaluation; outcome responses; quality of life issues; pharmaceutical trials; and neurogenetics of childhood headaches

Biography

Andrew Hershey, MD, PhD, FAHS, received his undergraduate degree at the University of Iowa, Iowa City, Iowa. He earned an honors degree in biochemistry; his research involved the enzyme kinetic properties of alcohol dehydrogenase in yeast.

After undergraduate school, Dr. Hershey attended the MD/PhD program at Washington University, St. Louis, Missouri. His PhD research thesis was entitled: "The Rat Substance P Receptor: cDNA and Genomic Cloning, Functional Expression, mRNA Distribution, and Mutational Analysis of Desensitization Responses."

After earning his MD and PhD, Dr. Hershey was an intern and resident in pediatrics at St. Louis Children's Hospital, St. Louis, MO. He then was an adult neurology resident at Barnes-Jewish Hospital, St. Louis, MO, followed by his child neurology fellowship at St. Louis Children's Hospital, St. Louis, MO.

After his fellowship, Dr. Hershey joined the faculty at Cincinnati Children's Hospital Medical Center, Ohio, within the University of Cincinnati College of Medicine, where he is director of the Headache Center.

Dr. Hershey's research interests currently include the improved diagnosis and treatment of childhood headache disorders, characterization of outcome responses, studies in new pharmacological and non-pharmacological treatment regimes, and the neurogenetics of migraines.

BS: University of Iowa, Iowa City, IA, 1985.

MD: Washington University, St. Louis, MO, 1992.

PhD: Washington University, St. Louis, MO, 1992.

Residency: St. Louis Childrens Hospital, St. Louis, MO, 1993-1994; Barnes-Jewish Hospital, St. Louis, MO,1994-1995.

Fellowship: St. Louis Childrens Hospital, St. Louis, MO, 1995-1997.

Certification: Neurology with special competence in child neurology, 1998, recertified 2008; Headache Medicine, 2006.

Hershey AD, Burdine D, Kabbouche MA, Powers SW. Genomic expression patterns in medication overuse headaches. Cephalalgia. 2011 Jan;31(2):161-71.

O'Brien HL, Kabbouche MA, Hershey AD. Treatment of acute migraine in the pediatric population. Curr Treat Options Neurol. 2010 May;12(3):178-85.

Hershey AD, Kabbouche MA, Powers SW. Treatment of pediatric and adolescent migraine. Pediatr Ann. 2010 Jul;39(7):416-23. Review.

Wang X, Xiang J, Wang Y, Pardos M, Meng L, Huo X, Korostenskaja M, Powers SW, Kabbouche MA, Hershey AD. Identification of abnormal neuromagnetic signatures in the motor cortex of adolescent migraine. Headache. 2010 Jun;50(6):1005-16.

Hershey AD. Recent developments in pediatric headache. Curr Opin Neurol. 2010 Jun;23(3):249-53. Review.

Hershey AD. Current approaches to the diagnosis and management of paediatric migraine. Lancet Neurol. 2010 Feb;9(2):190-204. Review.

Slater S, Crawford MJ, Kabbouche MA, LeCates SL, Cherney S, Vaughan P, Segers A, Manning P, Burdine D, Powers SS, Hershey AD. Effects of gender and age on paediatric headache. Cephalalgia. 2009 Sep;29(9):969-73.

Khatri R, Hershey AD, Wong B. Prochlorperazine -- treatment for acute confusional migraine. Headache. 2009 Mar;49(3):477-80.

Hershey AD. Menstrual migraine: how early can it start? Headache. 2009 Mar;49(3):348-9. Crawford MJ, Lehman L, Slater S, Kabbouche MA, LeCates SL, Segers A, Manning P, Powers SW, Hershey AD.

Menstrual migraine in adolescents. Headache. 2009 Mar;49(3):341-7.

Marielle A. Kabbouche, MD Director, Acute and Inpatient Headache Program 513-636-4222

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Marielle A. Kabbouche, MD

Director, Acute and Inpatient Headache Program

Child Neurologist, Division of Neurology

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-4222

Fax 513-636-1888

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Clinical

Headaches; migraines; acute and inpatient treatment of intractable headache

Research

Headache; outcome studies; health improvement; clinical effectiveness

Biography

Marielle Kabbouche, MD, received her training in child neurology at Vanderbilt University School of Medicine. She moved to Cincinnati for a specialty training in pediatric headache medicine. The position was the first for a pediatric neurologist.

After her headache training, she stayed at Cincinnati Children's as faculty and an active member of the center with involvement in all academic as well as clinical and teaching aspect of pediatric headaches. Since that time, she has been proud to be part of the maturing center that gradually developed to be the largest and most academically productive pediatric headache program in the United States and worldwide. She has been a co-PI on multiple NIH grants since 2002, and has been involved in multiple pharmaceutical and clinical studies in pediatric and adolescent migraines.

Her career has been focused on acute treatment of intractable migraines in children in emergency room, as well as inpatient, settings.

As the director of the inpatient headache unit, Dr. Kabbouche was actively involved in setting an acute headache infusion center as well as an inpatient headache unit at Cincinnati Children’s Hospital Medical Center. The headache acute care unit has been very productive in the last few years, seeing about 200-300 patients/year during peak seasons. The inpatient unit opened in July of 2011 bringing specialty care to headache patients with a team of six providers, fellows, residents and nurses. This approach to intractable headache care will have a great impact on patient’s outcome.

Dr. Kabbouche has over 25 publications and a track record of numerous book chapters and peer-reviewed papers, reviews, and abstracts in the field of headache medicine. She is also an editor of a pediatric headache book.

MD: Saint Joseph University, Faculty of Medicine, Beirut, Lebanon.

Residency: Vanderbilt University Medical Center, Nashville, TN.

Fellowship: Cincinnati Children's Hospital, Cincinnati, OH.

Hershey AD, Kabbouche MA, Powers SW. Treatment of pediatric and adolescent migraine. Pediatr Ann. 2010 Jul;39(7):416-23.

Kabbouche MA, Cleves C. Evaluation and management of children and adolescents presenting with an acute setting. Semin Pediatr Neurol. 2010 Jun;17(2):105-8.

Kabbouche MA, Powers SW, Segers A, LeCates S, Manning P, Biederman S, Vaughan P, Burdine D, Hershey AD. Inpatient treatment of status migraine with dihydroergotamine in children and adolescents. Headache. 2009 Jan;49(1):106-9.

Kabbouche MA, Gilman DK. Management of migraine in adolescents. Neuropsychiatr Dis Treat. 2008 Jun;4(3):535-48.

Kabbouche MA, Linder SL. Management of migraine in children and adolescents in the emergency department and inpatient setting. Curr Pain Headache Rep. 2005 Oct;9(5):363-7.

Kabbouche MA, Linder SL. Acute treatment of pediatric headache in the emergency department and inpatient settings. Pediatr Ann. 2005 Jun;34(6):466-71.

Kabbouche MA, Powers SW, Vockell ALB, LeCates SL, Ellinor PL, Segers A, Manning P, Hershey AD. Outcome of a multidisciplinary approach of pediatric migraine at 1, 2, and 5 years. Headache. 2005;45:1298-1303.

Book Chapters

Kabbouche MA. Migraine variants. In Andrew Hershey, Scott Powers, Paul Winners and Marielle Kabbouche (Eds.) Pediatric Headache in Clinical Practice. Wiley Blackwell, 2009.

Kabbouche MA. Other primary headaches. In Andrew Hershey, Scott Powers, Paul Winners and Marielle Kabbouche (Eds.) Pediatric Headache in Clinical Practice. Wiley Blackwell, 2009.

Kabbouche MA. Emergent therapy for children and adolescent. In Andrew Hershey, Scott Powers, Paul Winners and Marielle Kabbouche (Eds.) Pediatric Headache in Clinical Practice. Wiley Blackwell, 2009.

Anne M. Lynch-Jordan, PhD Pediatric Psychologist, Clinical, Behavioral Medicine & Clinical Psychology 513-636-4336 anne.lynch-jordan@cchmc.org

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Anne M. Lynch-Jordan, PhD

Pediatric Psychologist, Clinical, Behavioral Medicine & Clinical Psychology

Academic Affiliations

Associate Professor, UC Department of Pediatrics

Phone 513-636-4336

Fax 513-636-7756

Email anne.lynch-jordan@cchmc.org

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Clinical

Pediatric psychology; child and adolescent clinical psychology; behavioral pain management

Research

Psychosocial factors associated with pediatric chronic pain; child pain behaviors; parenting behaviors

Biography

Anne M. Lynch-Jordan, PhD, is a clinical psychologist specializing in the assessment and treatment of pediatric chronic pain. She is the primary pain psychologist in the Headache Center (named a Clinical Center of Excellence by Medical Economics in 2009), Epidermolysis Bullosa Center, and the Pain Management Clinic (named a Clinical Center of Excellence by the American Pain Society in 2007).

Dr. Lynch-Jordan is the associate director of the O'Grady Residency in Pediatric Psychology, and is a team leader in the Academic Collaborative, a hospital-wide initiative aimed at integrating quality improvement science into academic divisions at Cincinnati Children's.

Dr. Lynch-Jordan's current research interests include parenting behavior and illness behavior encouragement of children with chronic pain. Additionally, she is interested in pain expression and factors contributing to school attendance/absences in the pediatric chronic pain population. She is a study therapist for an NIH clinical trial investigating behavioral interventions for juvenile primary fibromyalgia syndrome.

PhD: Purdue University, West Lafayette, IN, 2003.

Internship: University of Florida Health Sciences Center, Gainesville, FL, 2002-03.

Fellowship: Cincinnati Children's Hospital Medical Center, 2003-05.

Kashikar-Zuck S, Flowers SR, Claar RL, Guite JW, Logan DE, Lynch-Jordan AM, Palermo TM, Wilson AC. Clinical utility and validity of the Functional Disability Inventory among a multicenter sample of youth with chronic pain. Pain. 2011 Jul;152(7):1600-7.

Lynch-Jordan AM, Kashikar-Zuck S, Goldschneider KR. Parent perceptions of adolescent pain expression: the adolescent pain behavior questionnaire. Pain. 2010 Dec;151(3):834-42.

Kashikar-Zuck S, Parkins IS, Ting TV, Verkamp E, Lynch-Jordan A, Passo M, Graham TB. Controlled follow-up study of physical and psychosocial functioning of adolescents with juvenile primary fibromyalgia syndrome. Rheumatology (Oxford). 2010 Nov;49(11):2204-9.

Kashikar-Zuck S, Flowers SR, Verkamp E, Ting TV, Lynch-Jordan AM, Graham TB, Passo M, Schikler KN, Hashkes PJ, Spalding S, Banez G, Richards MM, Powers SW, Arnold LM, Lovell D. Actigraphy-based physical activity monitoring in adolescents with juvenile primary fibromyalgia syndrome. J Pain. 2010 Sep;11(9):885-93.

Kashikar-Zuck S, Johnston M, Ting TV, Graham BT, Lynch-Jordan AM, Verkamp E, Passo M, Schikler KN, Hashkes PJ, Spalding S, Banez G, Richards MM, Powers SW, Arnold LM, Lovell D. Relationship between school absenteeism and depressive symptoms among adolescents with juvenile fibromyalgia. J Pediatr Psychol. 2010 Oct;35(9):996-1004.

Lynch-Jordan AM, Kashikar-Zuck S, Crosby LE, Lopez WL, Smolyansky BH, Parkins IS, Luzader CP, Hartman A, Guilfoyle SM, Powers SW. Applying quality improvement methods to implement a measurement system for chronic pain-related disability. J Pediatr Psychol. 2010 Jan-Feb;35(1):32-41.

Lynch-Jordan A, Kashikar-Zuck S, Flower S, Harding K, Wolf D, Paulford-Lecher N, Desai A, Szabova A, Goldschneider K. The relationship between adolescent pain behaviors and catastrophizing on parent catastrophizing about their adolescents’ pain. The Journal of Pain. 2010 11(4), (1 Suppl), 18.

Flowers S, Kashikar-Zuck S, Verkamp E, Lynch-Jordan A, Strotman D, Ting Schikler K, Spalding S, Hashkes P, Richards M, Banez G, Arnold L, Powers S, Lovell D. The relationship between pain catastrophizing, coping efficacy, and objectively measured physical activity in adolescents with Juvenile Primary Fibromyalgia Syndrome. The Journal of Pain. 2010 11(4), (1 Suppl), 16.

Zafar M, Kashikar-Zuck S, Slater S, Allen J, Flowers S, Verkamp E, Ting T, Lynch-Jordan A, Kabbouche M, Hershey A, Powers S. Childhood abuse in pediatric patients with juvenile fibromyalgia and chronic daily headache. The Journal of Pain. 2010 11(4), (1 Suppl), 13.

Kashikar-Zuck S, Lynch A, Slater S, Graham TB, Swain NF, Noll R. Family factors, emotional functioning, and functional impairment in juvenile fibromyalgia syndrome. Arthritis Care and Research. 2008 59(10),1392-98.

Hope L. O'Brien, MD Program Director, Headache Medicine Education 513-636-4222 neurodesk@cchmc.org

Scott W. Powers, PhD, ABPP Pediatric Psychologist, Research, Behavioral Medicine & Clinical Psychology 513-636-4336 scott.powers@cchmc.org

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Scott W. Powers, PhD, ABPP

Pediatric Psychologist, Research, Behavioral Medicine & Clinical Psychology

Co-director, Headache Center

Director, Office for Clinical and Translational Research

Co-director, Center for Child Behavior and Nutrition Research and Training

Director, Behavioral Science Core, Clinical Translational Research Center

Academic Affiliations

Professor, UC Department of Pediatrics

Phone 513-636-4336

Fax 513-636-7544

Email scott.powers@cchmc.org

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Specialties

Clinical trials; migraine/headache; pediatric pain; dietary adherence/nutrition and behavior; cystic fibrosis

Visit the Powers Lab.

AB: Wabash College, Crawfordsville, IN, 1985.

MS: Idaho State University, Pocatello, ID, 1987.

PhD: The University of Alabama, Tuscaloosa, AL, 1991.

Residency: Clinical Psychology, Brown University School of Medicine, Providence, RI.

Fellowship: Pediatric Psychology, Brown University School of Medicine / Rhode Island Hospital, Providence, RI.

Certification: Clinical Psychology, Ohio State Board of Psychology, 1992. American Board of Professional Psychology (ABPP), 2003.

Xiang J, deGrauw X, Korman AM, Allen JR, O’Brien MA, Powers SW, Hershey AD. Altered Cortical Activation in Adolescents with an Acute Migraine: A Magnetoencephalography Study. J Pain. 2013 Dec;14(12):1533-63.

Hershey AD, Powers SW, Coffey CS, Eklund DD, Chamberlin LA, Korbee LL; CHAMP Study Group. Childhood and Adolescent Migraine Prevention (CHAMP) Study: A Double-Blinded, Placebo-Controlled, Comparative Effectiveness Study of Amitriptyline, Topiramate, and Placebo in the Prevention of Childhood and Adolescent Migraine. Headache. 2013 May;53(5):799-816.

Kashikar-Zuck S, Sil S, Lynch-Jordan AM, Ting TV, Peugh J, Schikler KR, Hashkes PJ, Arnold LM, Passo MH, Richards MM, Powers SW, Lovell D. Changes in pain coping, catastrophizing and coping efficacy after cognitive-behavioral therapy in children and adolescents with juvenile fibromyalgia. J Pain. 2013 14(5):492-501.

Patton SR, Dolan LM, Chen M, Powers SW. Dietary Adherence and Mealtime Behaviors in Young Children with Type 1 Diabetes on Intensive Insulin Therapy. J Acad Nutr Diet. 2013 Feb;113(2):258-62.

Kashikar-Zuck S, Zafar M, Barnett KA, Aylward BS, Strotman D, Slater SK, Allen JR, LeCates SL, Kabbouche MA, Ting TV, Hershey AD, Powers SW. Quality of life and emotional functioning in youth with chronic migraine and juvenile fibromyalgia. Clin J Pain. 2013 Dec;29(12);1066-72.

Patton SR, Dolan LM, Powers SW. Does Eating During Television Viewing Affects Mealtime Behaviors in Young Children with Type 1 Diabetes Mellitus? J Pediatr Nurs. 2013 Jul-Aug:28(4):364-8.

Brannon EB, Kuhl ES, Benoit MR, Valenzuela J, Aylward B, Johnson SL, Boles RE, Powers SW. Strategies for Recruitment and Retention of Families from Low-Income and Minority Backgrounds in a Longitudinal Study of Caregiver Feeding and Child Weight. Children’s Health Care. 2013;42(3):198-213.

Guo X, Xiang J, Wang Y, O'Brien H, Kabbouche M, Horn P, Powers SW, Hershey AD Aberrant neuromagnetic activation in the motor cortex in children with acute migraine: a magnetoencephalography study. PLoS One. 20127(11):e50095.

Slater SK, Kashikar-Zuck SM, Allen JR, Lecates SL, Kabbouche MA, O'Brien HL, Hershey AD, Powers SW. Psychiatric comorbidity in pediatric chronic daily headache. Cephalalgia, 2012 Nov;32(15):1116-22.

Slater SK, Powers SW. Editorial on "Behavioral and emotional symptoms and primary headaches in children: A population-based study" by Arruda and Bigal. Cephalalgia,32(15): 1091-2. Nov, 2012.

Grants

Amitriptyline and Topiramate in the Prevention of Childhood Migraine. Principal Investigator, National Institute of Health and National Institute of Neurological Disorders and Stroke. Dec 2011-Dec 2016. #1U01NS076788-01.

NeuroNEXT: Neurological Trials Network. Co-Investigator, University of Cincinnati and Cincinnati Children’s Clinical Site (NIH/NINDS). 2012-2017.

Shalonda K. Slater, PhD Pediatric Psychologist, Clinical, Behavioral Medicine and Clinical Psychology 513-636-4336 shalonda.slater@cchmc.org

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Shalonda K. Slater, PhD

Pediatric Psychologist, Clinical, Behavioral Medicine and Clinical Psychology

Academic Affiliations

Assistant Professor, UC Department of Pediatrics

Phone 513-636-4336

Fax 513-636-7756

Email shalonda.slater@cchmc.org

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Clinical

Behavioral pain management; coping with chronic illness; psychosocial adjustment to transplant

Research

Family adjustment to chronic illness; child adjustment to chronic pain

Biography

Shalonda K. Slater, PhD, is an assistant professor in the Department of Pediatrics at Cincinnati Children’s Hospital Medical Center within the UC Department of Pediatrics.

She provides clinical care for children with chronic pain including children with headache, sickle cell disease and children awaiting transplantation. She is also a consultant for a NIH-funded pediatric chronic headache clinical trial which involves implementing a cognitive-behavioral-based intervention which focuses on coping and adherence.

She is a member of the Pain Quality Improvement team, part of a hospital-wide initiative aimed at integrating quality improvement science.

PhD: University of Florida, Gainesville, FL, 2007.

Internship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certification: Licensed Psychologist.