Center for Pulmonary Imaging Research

Publications

Walkup, LL; Roach, DJ; Hall, CS; Gupta, N; Thomen, RP; Cleveland, ZI; McCormack, FX; Woods, JC. Cyst Ventilation Heterogeneity and Alveolar Airspace Dilation as Early Disease Markers in Lymphangioleiomyomatosis. Annals of the American Thoracic Society. 2019; 16:1008-1016.

Walkup, LL; Myers, K; El-Bietar, J; Nelson, A; Willmering, MM; Grimley, M; Davies, SM; Towe, C; Woods, JC. Xenon-129 MRI detects ventilation deficits in paediatric stem cell transplant patients unable to perform spirometry. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2019; 53:1801779.

Bates, AJ; Higano, NS; Hysinger, EB; Fleck, RJ; Hahn, AD; Fain, SB; Kingma, PS; Woods, JC. Quantitative Assessment of Regional Dynamic Airway Collapse in Neonates via Retrospectively Respiratory-Gated 1 H Ultrashort Echo Time MRI. Journal of Magnetic Resonance Imaging. 2019; 49:659-667.

Higano, NS; Fleck, RJ; Spielberg, DR; Walkup, LL; Hahn, AD; Thomen, RP; Merhar, SL; Kingma, PS; Tkach, JA; Fain, SB; Woods, JC. Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT. Journal of Magnetic Resonance Imaging. 2017; 46:992-1000.

Higano, NS; Hahn, AD; Tkach, JA; Cao, X; Walkup, LL; Thomen, RP; Merhar, SL; Kingma, PS; Fain, SB; Woods, JC. Retrospective respiratory self-gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults. Magnetic Resonance in Medicine. 2017; 77:1284-1295.

Walkup, LL; Thomen, RP; Akinyi, TG; Watters, E; Ruppert, K; Clancy, JP; Woods, JC; Cleveland, ZI. Feasibility, tolerability and safety of pediatric hyperpolarized 129Xe magnetic resonance imaging in healthy volunteers and children with cystic fibrosis. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2016; 46:1651-1662.

Diamond, VM; Bell, LC; Bone, JN; Driehuys, B; Menchaca, M; Santyr, G; Svenningsen, S; Thomen, RP; Marshall, H; Smith, LJ; Woods, JC; Fain, SB; Eddy, RL; Rayment, JH. A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging. Journal of Magnetic Resonance Imaging. 2025; 62:625-639.

Durfey, SL; Kapnadak, SG; Pena, T; Willmering, MM; Godwin, JD; Teresi, ME; Heltshe, SL; Vo, AT; Villacreses, RA; Aliukonyte, I; Tiddens, HA W M; Woods, JC; Stoltz, DA; Singh, PK. Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation. Cell Host and Microbe. 2025; 33:S1931-3128(25)00281-1.

Haney, M; Ashraf, A; Lake, KE; Strecker, L; Myers, KC; Towe, C; Walkup, L; Woods, J; Edwards, SL; Cooper, R; Goldfarb, SB; Davies, SM; Koo, J; Groups, T. Community respiratory viruses are generally welltolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study. Haematologica: the hematology journal. 2025; 110:1882-1886.

Koo, J; Cooper, R; Edwards, SL; Lane, A; Loveless, SK; Strecker, L; Lake, KE; Myers, KC; Towe, C; Patti, J; Li, M; Goldfarb, SB; Woods, JC; Davies, SM. High Prevalence of Abnormal Baseline Lung Function in Pediatric and Young Adult Hematopoietic Stem Cell Transplant Recipients: A Report from the TRANSPIRE Study. Pediatric Blood and Cancer. 2025; e31916.

Kieninger, E; Munidasa, S; Curdy, M; Streibel, C; Zanette, B; Woods, J; Latzin, P; Ratjen, F; Santyr, G. Application of the defect distribution index to functional lung MRI of pediatric cystic fibrosis lung disease and controls. Journal of Cystic Fibrosis. 2025; 24:809-815.

Dournes, G; Woods, JC. Chronic Pediatric Lung Diseases: Counterpoint-A Growing Role for MRI. American Journal of Roentgenology. 2025; 224:e2432405.

Dianova, E; Higano, NS; McNelis, KM; Ehrlich, SR; Liu, C; Woods, JC; Kingma, PS. Association of Early Nutrition with Bronchopulmonary Dysplasia Severity and Magnetic Resonance Imaging Lung Characteristics in Preterm Infants. Neonatology: foetal and neonatal research. 2025; 122:319-328.

Fletcher, C; Slife, M; McConnell, K; Fleck, R; Li, C; Amin, R; Xiao, Q; Bates, A. 1011 Comparison of MRI-based Dynamic 4D Airway Measurements and DISE Results in Pediatric Patients with Persistent OSA. Sleep. 2025; 48:a437-a438.

Xiao, Q; Ignatiuk, D; Gunatilaka, C; McConnell, K; Schuler, c; Romaker, A; Ishman, S; Fleck, R; Amin, R; Bates, A. 0452 Quantification of How Hypoglossal Nerve Stimulation Affects Upper Airway Neuromuscular Control Using Computational Airflow Modeling. Sleep. 2025; 48:a197-a198.

Boles, C; Gunatilaka, CC; Xiao, Q; Woods, JC; Kingma, PS; Higano, NS; Bates, A. Computational Fluid Dynamics Analysis of Tracheal Pressure Difference in Neonates With Tracheoesophageal Fistulas Before and After Surgical Repair. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a5119.

Lyman, BC; Burg, G; Woods, JC. Frequency of Various Combinations of Static and Dynamic Airway Findings From Flexible Bronchoscopy in Patients With Trisomy 21. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a2301.

Matheson, AM; Bdaiwi, AS; Willmering, M; DiFrancesco, MW; Cleveland, ZI; Woods, JC. Pulmonary 129 Xe Ventilation MRI Predicts Severe Exacerbations in People With CF. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7088.

Stewart, NJ; Higano, NS; Wucherpfennig, L; Triphan, SM F; Simmons, A; Smith, LJ; Wielpütz, MO; Woods, JC; Wild, JM. Pulmonary MRI in Newborns and Children. Journal of Magnetic Resonance Imaging. 2025; 61:2094-2115.

Klimeš, F; Plummer, JW; Willmering, MM; Matheson, AM; Bdaiwi, AS; Gutberlet, M; Voskrebenzev, A; Wernz, MM; Wacker, F; Woods, J; Cleveland, ZI; Walkup, LL; Vogel-Claussen, J. Quantifying spatial and dynamic lung abnormalities with 3D PREFUL FLORET UTE imaging: A feasibility study. Magnetic Resonance in Medicine. 2025; 93:1984-1998.

Mohanakrishnan, M; Munidasa, SR; Higano, NS; Willmering, M; Hoyos Cordon, X; Bullard Elias, D; Bates, AJ; Kingma, PS; Hysinger, EB; Woods, JC. Serial MRI Evaluation of Tracheomalacia Changes in Neonates With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a1284.

Munidasa, S; Higano, NS; Zinjal, R; Willmering, M; Kingma, PS; Critser, PJ; Hysinger, E; Woods, JC. Structural and Functional Cardiopulmonary Magnetic Resonance Imaging in Neonates With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a1279.

Jo, S; Arroyo, R; Marks, K; Higano, NS; Bates, A; von Allenmen, D; Woods, JC; Kingma, PS. Evaluation of Magnetic Resonance Imaging (MRI) Anatomic Risk Factors to Predict Outcomes in Patients With Esophageal Atresia (EA). American Journal of Respiratory and Critical Care Medicine. 2025; 211:a2299.

Bullard Elias, D; Amin, RS; Bellew, L; Woods, JC; Hysinger, E. Reversible Obstructive Lung Disease in Pre-school Children With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a1276.

Papathanasiou, AE; Miles, KG; Willmering, M; Zinjal, R; Parikh, N; Hysinger, EB; Woods, JC; Critser, PJ. School-aged Children With History of Prematurity and Bronchopulmonary Dysplasia Demonstrate Alterations in Cardiac Performance and Evidence of Pulmonary Vascular Disease. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7233.

Prather, E; Matheson, AM; Willmering, M; Mata, J; Fain, SB; Santyr, G; Ratjen, FA; Woods, JC. Clearance of Mucus Plugs Drives Functional Improvement in Pediatric CF After Highly-effective CFTR Therapy. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a5128.

Munidasa, SR; Zinjal, R; Papathanasiou, AE; Miles, K; Willmering, M; Woods, JC; Hysinger, EB; Critser, PJ. Cardiopulmonary Magnetic Resonance Imaging Evaluation in Children With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a1281.

Gunatilaka, CC; Xiao, Q; McConnell, K; Sketch, M; Wallace, C; Hales, J; Cummins, A; Schierling, R; Kaul, A; Woods, JC; Bates, A; Hysinger, E. Quantifying the Effect of Albuterol on Tracheal and Lung Compliance. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a7086.

Munidasa, SR; Higano, NS; Willmering, M; Bdaiwi, AS; Hoyos Cordon, X; Bullard Elias, D; Kingma, PS; Hysinger, EB; Woods, JC. Magnetic Resonance Imaging Captures the Short-Term Trajectory of Parenchymal Lung Disease in Infants With Bronchopulmonary Dysplasia. American Journal of Respiratory and Critical Care Medicine. 2025; 211:a1280.

Walkup, LL; Roach, DJ; Plummer, JW; Willmering, MM; Zanette, B; Santyr, G; Fain, SB; Rock, MJ; Mata, J; Froh, D; Stanojevic, S; Cleveland, ZI; Ratjen, F; Woods, JC. Same-Day Repeatability and 28-Day Reproducibility of Xenon MRI Ventilation in Children With Cystic Fibrosis in a Multi-Site Trial. Journal of Magnetic Resonance Imaging. 2025; 61:1664-1674.

Bdaiwi, AS; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying Spatial Distribution of Ventilation Defects in Multiple Pulmonary Diseases With Hyperpolarized 129Xenon MRI. Journal of Magnetic Resonance Imaging. 2025; 61:1860-1873.

Woods, JC. Lung MRI: The future is now. Pediatric Pulmonology. 2025; 60 Suppl 1:S73-S74.

Bdaiwi, AS; Willmering, MM; Plummer, JW; Hussain, R; Roach, DJ; Parra-Robles, J; Niedbalski, PJ; Woods, JC; Walkup, LL; Cleveland, ZI. 129Xe Image Processing Pipeline: An open-source, graphical user interface application for the analysis of hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2025; 93:1220-1237.

Matheson, AM; Johnstone, J; Niedbalski, PJ; Woods, JC; Castro, M. New frontiers in asthma chest imaging. Journal of Allergy and Clinical Immunology. 2025; 155:241-254.e1.

Mukthapuram, S; Donaher, A; Higano, NS; Rowe, JA; Tkach, JA; Woods, JC; Kingma, PS. Magnetic Resonance Imaging Assessment of Pulmonary Vascularity in Preterm Infants with Bronchopulmonary Dysplasia. Neonatology: foetal and neonatal research. 2025; 122:76-83.

Willmering, MM; Albert, BJ; Plummer, JW; Greer, J; Walkup, LL; Lindquist, DM; Cleveland, ZI. A thermally polarized, dissolved-phase 129Xe phantom for quality-control and multisite comparisons of gas-exchange imaging. Journal of Magnetic Resonance. 2025; 371:107829.

Willmering, MM; Krishnamoorthy, G; Robison, RK; Rosenberg, JT; Woods, JC; Pipe, JG. High-quality FLORET UTE imaging for clinical translation. Magnetic Resonance in Medicine. 2025; 93:276-288.

Zak, SM; Onge, IS; Higano, NS; Bates, AJ; Gandhi, D; Fleck, RJ; Kingma, PS; Woods, JC; Hysinger, EB. Clinical Outcomes Through Two Years for Infants With Bronchopulmonary Dysplasia and Tracheomalacia. Pediatric Pulmonology. 2025; 60:e27383.

Liu, CM; Fischer, JL; Zemanick, ET; Woods, JC; Markarian, KK; Fain, SB; Froh, D; Heltshe, SL; Hoffman, LR; Humphries, SM; Trout, AT; Goss, CH; Taylor-Cousar, JL; Beswick, DM. The impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol. ERJ Open Research. 2025; 11:137-2024.

Anderson, MA; Masokano, BI; Plummer, JW; Willmering, MM; Krivchenia, K; Towe, CT; Walkup, LL. Xe Ventilation and Gas-Exchange MRI Abnormalities in Children with Neuroendocrine Cell Hyperplasia of Infancy (NEHI). Pediatric Pulmonology. 2025; 60:e27410.

Soderlund, SA; Bdaiwi, AS; Plummer, JW; Woods, JC; Walkup, LL; Cleveland, ZI. Improved Diffusion-Weighted Hyperpolarized 129Xe Lung MRI with Patch-Based Higher-Order, Singular Value Decomposition Denoising. Academic Radiology. 2024; 31:5289-5299.

Xiao, Q; Gunatilaka, C; McConnell, K; Bates, A. The effect of including dynamic imaging derived airway wall motion in CFD simulations of respiratory airflow in patients with OSA. Scientific Reports. 2024; 14:17242.

Xiao, Q; Bates, AJ; Doorly, DJ. Effects of decongestion on nasal cavity air conditioning efficiency: a CFD cohort study. Scientific Reports. 2024; 14:8482.

Gunatilaka, CC; McKenzie, C; Xiao, Q; Higano, NS; Woods, JC; Bates, AJ. Effect of airway wall motion on particle deposition and delivery in the neonatal trachea. Journal of Aerosol Science. 2024; 182:106450.

Miller, JE; Liu, CM; Zemanick, ET; Woods, JC; Goss, CH; Taylor-Cousar, JL; Beswick, DM. Olfactory loss in people with cystic fibrosis: Community perceptions and impact. Journal of Cystic Fibrosis. 2024; 23:1195-1198.

von Allmen, DC; Hysinger, EB; Bates, AJ; Higano, NS; Garrison, A; Walther, A; de Alarcon, A; Woods, J; Kingma, P. Correlation of Tracheomalacia Severity With Esophageal Gap Length as Assessed by Ultrashort Echo-time MRI. Journal of Pediatric Surgery. 2024; 59:161880.

Costa, ML; Plummer, JW; Bdaiwi, AS; Albert, BJ; Fugate, EM; Niedbalski, PJ; Lindquist, DM; Cleveland, ZI. Hyperpolarized 129Xe Lung MRI and Spectroscopy in Mechanically Ventilated Mice. Jove-Journal of Visualized Experiments. 2024.

Plummer, JW; Hussain, R; Bdaiwi, AS; Soderlund, SA; Hoyos, X; Lanier, JM; Garrison, WJ; Parra-Robles, J; Willmering, MM; Niedbalski, PJ; Cleveland, ZI; Walkup, LL. A decay-modeled compressed sensing reconstruction approach for non-Cartesian hyperpolarized 129Xe MRI. Magnetic Resonance in Medicine. 2024; 92:1363-1375.

Gunatilaka, CC; Xiao, Q; Bates, AJ; Franz, AR; Poets, CF; Maiwald, CA. Influence of catheter thickness on respiratory physiology during less invasive surfactant administration in extremely preterm infants. Frontiers in Pediatrics. 2024; 12:1352784.

Durfey, S; Kapnadak, S; Teresi, M; Gambol, T; Willmering, M; Godwin, J; Boyken, L; Stroik, M; Singh, S; Steele, C; Pena, T; Clancy, J; Aitken, M; Singh, P. 2 Multi-lobe bronchoscopy reveals ETI's effects on regional lung infection and inflammation. Journal of Cystic Fibrosis. 2024; 23:s1-s2.

Matheson, AM; Tanimoto, A; Woods, JC. Imaging in Pediatric Lung Disease: Current Practice and Future Directions. Clinics in Chest Medicine. 2024; 45:569-585.

Bdaiwi, AS; Svoboda, AM; Murdock, KE; Hendricks, A; Hossain, MM; Kramer, EL; Brewington, JJ; Willmering, MM; Woods, JC; Walkup, LL; Cleveland, ZI. Quantifying abnormal alveolar microstructure in cystic fibrosis lung disease via hyperpolarized 129Xe diffusion MRI. Journal of Cystic Fibrosis. 2024; 23:926-935.

Skala, E; Banerjee, R; Siefert, M; Dusa, C; Stevens, C; Hils, B; Bdaiwi, A; Hayes, D; Cleveland, Z; Ziady, A. 846 Plasma proteomics identifies changes in disease-associated pathways in subjects with CF bronchiectasis after elexacaftor/tezacaftor/ivacaftor initiation. Journal of Cystic Fibrosis. 2024; 23:s490.

Plummer, JW; Hussain, R; Bdaiwi, AS; Costa, ML; Willmering, MM; Parra-Robles, J; Cleveland, ZI; Walkup, LL. Analytical corrections for B1-inhomogeneity and signal decay in multi-slice 2D spiral hyperpolarized 129Xe MRI using keyhole reconstruction. Magnetic Resonance in Medicine. 2024; 92:967-981.

Bjorkman, KR; Miles, KG; Bellew, LE; Schneider, KA; Magness, SM; Higano, NS; Ollberding, NJ; Cordon, XH; Hirsch, RM; Hysinger, E; Woods, JC; Critser, PJ. Patent Ductus Arteriosus and Lung Magnetic Resonance Imaging Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. 2024; 210:318-328.

Stecker, IR; Bdaiwi, AS; Niedbalski, PJ; Chatterjee, N; Hossain, MM; Cleveland, ZI. Impact of undersampling on preclinical lung T2* mapping with 3D radial UTE MRI at 7 T. Journal of Magnetic Resonance. 2024; 365:107741.

Shanthikumar, S; Goldfarb, S; Abts, M; Barochia, A; Bergeron, A; Blinman, T; Bracken, J; Calvo, C; Casey, A; Charbek, E; Teusink-Cross, A; Towe, CT; Walkup, LL; Yanik, GA. Detection of Bronchiolitis Obliterans Syndrome after Pediatric Hematopoietic Stem Cell Transplantation: An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine. 2024; 210:262-280.

Higano, NS. Editorial for "Assessment of Pulmonary Ventilation Using 3D Ventilation Flow-Weighted and Ventilation-Weighted Maps From 3D Ultrashort Echo-Time (UTE) MRI ". Journal of Magnetic Resonance Imaging. 2024; 60:495-496.

Gandhi, DB; Higano, NS; Hahn, AD; Gunatilaka, CC; Torres, LA; Fain, SB; Woods, JC; Bates, AJ. Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI. Biomedical Physics and Engineering Express. 2024; 10:035030.

Gunatilaka, CC; McKenzie, C; Hysinger, EB; Xiao, Q; Higano, NS; Woods, JC; Bates, AJ. Tracheomalacia Reduces Aerosolized Drug Delivery to the Lung. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2024; 37:19-29.

Towe, C; Patti, J; Stevens, CA; Myers, KC; Cook, E; Cooper, R; Abts, MF; Baker, KS; Ballard, S; Urrego, FA; Melton, A; Noori, S; Woods, JC; Davies, SM; Goldfarb, SB. Feasibility of Home Spirometry for Early Identification of Pulmonary Dysfunction after HSCT in the Transpire Research Study. Transplantation and Cellular Therapy. 2024; 30:s138-s139.

Abts, MF; Silva-Carmona, M; Allen, JL; Doherty, EE; Baker, S; MacMillan, ML; Genatassio, A; Lacher, P; Griffin, T; Tekman, M; Edwards, SL; Woods, JC; Davies, SM; Goldfarb, SB. Success and Feasibility of Multiple Breath Washout: Prospective, Multi-Center Results from the Transpire Study. Transplantation and Cellular Therapy. 2024; 30:s142-s143.

Giltmier, AJ; Higano, NS; Woods, JC; Kingma, PS. Evaluation of regional lung mass and growth in neonates with bronchopulmonary dysplasia using ultrashort echo time magnetic resonance imaging. Pediatric Pulmonology. 2024; 59:55-62.

Xiao, Q; Ignatiuk, D; McConnell, K; Gunatilaka, C; Schuh, A; Fleck, R; Ishman, S; Amin, R; Bates, A. The interaction between neuromuscular forces, aerodynamic forces, and anatomical motion in the upper airway predicts the severity of pediatric OSA. Journal of applied physiology (Bethesda, Md. : 1985). 2024; 136:70-78.

Uehara, Y; Tanaka, Y; Zhao, S; Nikolaidis, NM; Pitstick, LB; Wu, H; Yu, JJ; Zhang, E; Hasegawa, Y; Noel, JG; Inoue, Y; Altinişik, G; Xu, Y; McCormack, FX. Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis. Nature Communications. 2023; 14:1205.

Roach, DJ; Szugye, NA; Moore, RA; Hossain, MM; Morales, DL S; Hayes, D; Towe, CT; Zafar, F; Woods, JC. Improved donor lung size matching by estimation of lung volumes based on chest X-ray measurements. Pediatric Transplantation. 2023; 27:e14594.

Stewart, NJ; Higano, NS; Mukthapuram, S; Willmering, MM; Loew, W; West, M; Arnsperger, A; Pratt, R; Rao, MR; Schulte, RF; Wild, JM; Woods, JC. Initial feasibility and challenges of hyperpolarized 129 Xe MRI in neonates with bronchopulmonary dysplasia. Magnetic Resonance in Medicine. 2023; 90:2420-2431.

Ratjen, F; Stanojevic, S; Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Woods, J. 129 Response in imaging and lung function outcomes in the HyPOINT study. Journal of Cystic Fibrosis. 2023; 22:s68-s69.

Durfey, S; Kapnadak, S; Radey, M; Teresi, M; Gambol, T; Hayden, H; Willmering, M; Godwin, J; Boyken, L; Stroik, M; Clancy, J; Aitken, M; Feder, A; Singh, P. 57 Bronchoscopy sampling finds that intra-lung bacterial migration contributes to persistent Pseudomonas aeruginosa infection after elexacaftor-tezacaftor-ivacaftor. Journal of Cystic Fibrosis. 2023; 22:s31.

Qiwei, X; Chmiel, J; Mylavarapu, G; Fleck, R; Nakamura, A; Hossain, M; Bates, A; Naren, A; Estepar, R; Amin, R. 720 Pulmonary vascular remodeling in cystic fibrosis begins early in the disease and at a young age. Journal of Cystic Fibrosis. 2023; 22:s397-s398.

Alam, FS; Zanette, B; Munidasa, S; Braganza, S; Li, D; Woods, JC; Ratjen, F; Santyr, G. Intra- and Inter-visit Repeatability of 129 Xenon Multiple-Breath Washout MRI in Children With Stable Cystic Fibrosis Lung Disease. Journal of Magnetic Resonance Imaging. 2023; 58:936-948.

West, ME; Spielberg, DR; Roach, DJ; Willmering, MM; Bdaiwi, AS; Cleveland, ZI; Woods, JC. Short-term structural and functional changes after airway clearance therapy in cystic fibrosis. Journal of Cystic Fibrosis. 2023; 22:926-932.

Willmering, MM; Bdaiwi, AS; Kaspy, KR; Racadio, J; Machogu, EM; Kwan, OA; Cheng, PC; Woods, JC; Hysinger, EB. MRI assessment and guidance for regionally targeted pulmonary interventions. Pediatric Pulmonology. 2023; 58:2386-2388.

Xiao, Q; Stewart, N; Willmering, M; McConnell, K; Woods, J; Fleck, R; Amin, R; Bates, A. Phase-Contrast Magnetic Resonance Imaging of Inhaled Xenon Reveals the Relationship between Airflow and Obstruction in Obstructive Sleep Apnea. American Journal of Respiratory and Critical Care Medicine. 2023; 208:e5-e6.

Bdaiwi, AS; Costa, ML; Plummer, JW; Willmering, MM; Walkup, LL; Cleveland, ZI. B1 and magnetization decay correction for hyperpolarized 129 Xe lung imaging using sequential 2D spiral acquisitions. Magnetic Resonance in Medicine. 2023; 90:473-482.

Durfey, SL; Kapnadak, SG; Teresi, M; Gambol, T; Radey, MC; Hayden, HS; Willmering, MM; Godwin, JD; Boyken, L; Stroik, M; Clancy, JP; Aitken, ML; Feder, AF; Singh, PK. WS13.06 Regional bronchoscopy sampling indicates that Pseudomonas aeruginosa infections persist throughout the lung after elexacaftor/tezacaftor/ivacaftor (ETI) due to intra-lung bacterial migration. Journal of Cystic Fibrosis. 2023; 22:s27.

Dani, A; Hayes, D; Guzman-Gomez, A; Hossain, MM; Woods, JC; Morales, DL S; Hirsch, R; Zafar, F; Hysinger, EB. Lung Transplantation for Bronchopulmonary Dysplasia. Chest. 2023; 163:1166-1175.

Munidasa, S; Zanette, B; Couch, M; Grimm, R; Seethamraju, R; Dumas, MP; Wee, W; Au, J; Braganza, S; Li, D; Woods, J; Ratjen, F; Santyr, G. Inter- and intravisit repeatability of free-breathing MRI in pediatric cystic fibrosis lung disease. Magnetic Resonance in Medicine. 2023; 89:2048-2061.

Bdaiwi, AS; Willmering, MM; Wang, H; Cleveland, ZI. Diffusion weighted hyperpolarized 129 Xe MRI of the lung with 2D and 3D (FLORET) spiral. Magnetic Resonance in Medicine. 2023; 89:1342-1356.

Plummer, JW; Willmering, MM; Cleveland, ZI; Towe, C; Woods, JC; Walkup, LL. Childhood to adulthood: Accounting for age dependence in healthy-reference distributions in 129 Xe gas-exchange MRI. Magnetic Resonance in Medicine. 2023; 89:1117-1133.

Marks, KT; Higano, NS; Kotagal, M; Woods, JC; Kingma, PS. Magnetic Resonance Imaging-Based Evaluation of Anatomy and Outcome Prediction in Infants with Esophageal Atresia. Neonatology: foetal and neonatal research. 2023; 120:185-195.

Hsia, CC W; Hopkins, SR; Bates, JH T; Driehuys, B; Fain, SB; Goldin, JG; Hoffman, EA; Hogg, JC; Levin, DL; Lynch, DA; Smith, BM; Tawhai, M; Vidal Melo, MF; Woods, JC. Quantitative Imaging Metrics for the Assessment of Pulmonary Pathophysiology: An Official American Thoracic Society and Fleischner Society Joint Workshop Report. Annals of the American Thoracic Society. 2023; 20:161-195.

Lampl, CD; Wikenheiser-Brokamp, KA; Woods, JC; Matthew Kofron, J; McCormack, FX. Pulmonary Alveolar Microlithiasis. Orphan Lung Diseases. : Springer Nature; Springer Nature; 2023.

Hysinger, EB; Woods, JC. Seeing Premature Lung Disease: Hyperpolarized Xe Magnetic Resonance Imaging. American Journal of Respiratory and Critical Care Medicine. 2023; 207:15-16.

Tkach, JA; Higano, NS; Taylor, MD; Moore, RA; Hossain, M; Huang, G; Spielberg, DR; Fain, SB; Kingma, PS; Woods, JC. Quantitative cardiopulmonary magnetic resonance imaging in neonatal congenital diaphragmatic hernia. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2022; 52:2306-2318.

Ignatiuk, D; Xiao, Q; McConnell, K; Fleck, R; Schuler, C; Schuh, A; Amin, R; Bates, A. Computational assessment of upper airway muscular activity in obstructive sleep apnea - In vitro validation. Journal of Biomechanics. 2022; 144:111304.

Gunatilaka, CC; Hysinger, EB; Schuh, A; Xiao, Q; Gandhi, DB; Higano, NS; Ignatiuk, D; Hossain, MM; Fleck, RJ; Woods, JC; Bates, AJ. Predicting tracheal work of breathing in neonates based on radiological and pulmonary measurements. Journal of applied physiology (Bethesda, Md. : 1985). 2022; 133:893-901.

Walkup, L; Roach, D; Zanette, B; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Stanojevic, S; Ratjen, F; Woods, J. 165 Hyperpolarized xenon gas ventilation magnetic resonance imaging detects lung ventilation improvement in children with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor in a multisite study. Journal of Cystic Fibrosis. 2022; 21:s97.

Durfey, S; Kapnadak, S; Godwin, J; Gambol, T; Teresi, M; Willmering, M; Boyken, L; Stroik, M; Vo, A; McGeer, K; Pena, T; Clancy, J; Aitken, M; Singh, P. 564 Regional lung sampling after elexacaftor/tezacaftor/ivacaftor reveals Pseudomonas aeruginosa persistence in high- and low-damage segments. Journal of Cystic Fibrosis. 2022; 21:s314.

Willmering, MM; Walkup, LL; Niedbalski, PJ; Wang, H; Wang, Z; Hysinger, EB; Myers, KC; Towe, CT; Driehuys, B; Cleveland, ZI; Woods, JC. Pediatric 129 Xe Gas-Transfer MRI-Feasibility and Applicability. Journal of Magnetic Resonance Imaging. 2022; 56:1207-1219.

Dumas, M; Jensen, R; Shaw, M; West, A; Munidasa, S; Zanette, B; Alam, F; Woods, J; Robinson, P; Santyr, G; Ratjen, F. 161 Elexacaftor/tezacaftor/ivacaftor reduces trapped gas in children with cystic fibrosis. Journal of Cystic Fibrosis. 2022; 21:s95.

Kao, DD; Buck, LS; Hysinger, EB; Bates, AJ; Gunatilaka, CC; Rutter, MJ. Laryngotracheal separation through the cricoid ring for management of tracheobronchomegaly. International Journal of Pediatric Otorhinolaryngology. 2022; 161:111266.

Higano, NS; Gandhi, DB; Xiao, Q; Gunatilaka, CC; Hysinger, EB; Fleck, RJ; Woods, JC; Bates, AJ. Virtual Bronchoscopy of Neonatal Airway Malacia via High-Resolution, Respiratory-gated Magnetic Resonance Imaging. American Journal of Respiratory and Critical Care Medicine. 2022; 206:e42-e43.

Hysinger, EB; Higano, NS; Critser, PJ; Woods, JC. Imaging in neonatal respiratory disease. Paediatric Respiratory Reviews. 2022; 43:44-52.

Zou, Q; Torres, LA; Fain, SB; Higano, NS; Bates, AJ; Jacob, M. Dynamic imaging using motion-compensated smoothness regularization on manifolds (MoCo-SToRM). Physics in Medicine and Biology. 2022; 67:144001.

Higano, NS; Cao, X; Guo, J; Wang, X; Kroenke, CD; Filuta, AL; Bridges, JP; Woods, JC. Fetal lung development via quantitative biomarkers from diffusion MRI and histological validation in rhesus macaques. Journal of Perinatology. 2022; 42:866-872.

Hayes, D; Shukla, RK; Cheng, Y; Gecili, E; Merling, MR; Szczesniak, RD; Ziady, AG; Woods, JC; Hall-Stoodley, L; Liyanage, NP M; Robinson, RT. Tissue-localized immune responses in people with cystic fibrosis and respiratory nontuberculous mycobacteria infection. JCI insight. 2022; 7:e157865.

Adaikalam, SA; Higano, NS; Hysinger, EB; Bates, AJ; Fleck, RJ; Schapiro, AH; House, MA; Nathan, AT; Ahlfeld, SK; Brady, JM; Woods, JC; Kingma, PS. Tracheostomy prediction model in neonatal bronchopulmonary dysplasia via lung and airway MRI. Pediatric Pulmonology. 2022; 57:1042-1050.

Adaikalam, SA; Higano, NS; Hysinger, EB; Bates, AJ; Fleck, RJ; Schapiro, AH; House, MA; Nathan, AT; Ahlfeld, SK; Brady, JM; Woods, JC; Kingma, PS. Cover Image, Volume 57, Number 4, April 2022. Pediatric Pulmonology. 2022; 57:ii.

Higano, NS; Bates, AJ; Gunatilaka, CC; Hysinger, EB; Critser, PJ; Hirsch, R; Woods, JC; Fleck, RJ. Bronchopulmonary dysplasia from chest radiographs to magnetic resonance imaging and computed tomography: adding value. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2022; 52:643-660.

Riccetti, MR; Ushakumary, MG; Waltamath, M; Green, J; Snowball, J; Dautel, SE; Endale, M; Lami, B; Woods, J; Ahlfeld, SK; Perl, AK T. Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation. JCI insight. 2022; 7:e152404.

Bdaiwi, AS; Niedbalski, PJ; Hossain, MM; Willmering, MM; Walkup, LL; Wang, H; Thomen, RP; Ruppert, K; Woods, JC; Cleveland, ZI. Improving hyperpolarized 129 Xe ADC mapping in pediatric and adult lungs with uncertainty propagation. NMR in Biomedicine. 2022; 35:e4639.

Critser, PJ; Evers, PD; Schneider, K; Hirsch, R; Taylor, MD; Woods, JC; Lang, SM. Echocardiography-derived septal curvature correlated with invasive hemodynamics in pediatric pulmonary hypertension. Journal of Echocardiography. 2022; 20:24-32.

Dournes, G; Hall, CS; Willmering, MM; Brody, AS; Macey, J; Bui, S; de Senneville, BD; Berger, P; Laurent, F; Benlala, I; Woods, JC. Artificial intelligence in computed tomography for quantifying lung changes in the era of CFTR modulators. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2022; 59:2100844.

Roach, DJ; Willmering, MM; Plummer, JW; Walkup, LL; Zhang, Y; Hossain, MM; Cleveland, ZI; Woods, JC. Hyperpolarized 129Xenon MRI Ventilation Defect Quantification via Thresholding and Linear Binning in Multiple Pulmonary Diseases. Academic Radiology. 2022; 29 Suppl 2:S145-S155.

Cristea, AI; Baker, CD; Allen, J; Amin, R; Austin, ED; Cataletto, ME; Collaco, JM; Eldredge, LC; Fleck, RJ; Gelfand, A; Teper, A; Tracy, MC; Watters, KF; Woods, JC. Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine. 2021; 204:e115-e133.

Gunatilaka, CC; Hysinger, EB; Schuh, A; Gandhi, DB; Higano, NS; Xiao, Q; Hahn, AD; Fain, SB; Fleck, RJ; Woods, JC; Bates, AJ. Neonates With Tracheomalacia Generate Auto-Positive End-Expiratory Pressure via Glottis Closure. Chest. 2021; 160:2168-2177.

Mukthapuram, S; Beebe, J; Tkach, JA; Arya, S; Haberman, B; Peiro, J; Lim, FY; Woods, JC; Kingma, PS. Magnetic Resonance Imaging Assessment of Pulmonary Vascularity in Infants with Congenital Diaphragmatic Hernia: A Novel Tool for Direct Assessment of Severity of Pulmonary Hypertension and Hypoplasia. The Journal of Pediatrics. 2021; 239:89-94.

Niedbalski, PJ; Hall, CS; Castro, M; Eddy, RL; Rayment, JH; Svenningsen, S; Parraga, G; Zanette, B; Santyr, GE; Thomen, RP; Driehuys, B; Willmering, MM; Cleveland, ZI; Woods, JC. Protocols for multi-site trials using hyperpolarized 129 Xe MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the 129 Xe MRI clinical trials consortium. Magnetic Resonance in Medicine. 2021; 86:2966-2986.

Walkup, LL; Myers, KC; Willmering, MM; Mehta, PA; Nelson, AS; Fleck, RJ; Woods, JC; Davies, SM; Towe, CT. Modern Lung Magnetic Resonance Imaging to Screen for Pulmonary Complications in Patients with Dyskeratosis Congenita. American Journal of Respiratory and Critical Care Medicine. 2021; 204:1340-1343.

Xiao, Q; Bates, AJ; Cetto, R; Doorly, DJ. The effect of decongestion on nasal airway patency and airflow. Scientific Reports. 2021; 11:14410.

Walkup, L; Roach, D; Santyr, G; Fain, S; Rock, M; Mata, J; Froh, D; Stanojevic, S; Ratjen, F; Woods, J. 537: 129Xe MRI is a repeatable measure of regional ventilation in children with stable CF. Journal of Cystic Fibrosis. 2021; 20:s253-s254.

Dumas, M; Jensen, R; Au, J; Munidasa, S; Woods, J; Robinson, P; Santyr, G; Ratjen, F. 536: Evaluation of volume of trapped gas by multiple-breath washout and functional MRI in children with cystic fibrosis. Journal of Cystic Fibrosis. 2021; 20:s253.

Zafar, MA; Sengupta, R; Bates, A; Woods, JC; Radchenko, C; McCormack, FX; Panos, RJ. Oral Positive Expiratory Pressure Device for Excessive Dynamic Airway Collapse Caused by Emphysema. Chest. 2021; 160:e333-e337.

Xiao, Q; Stewart, NJ; Willmering, MM; Gunatilaka, CC; Thomen, RP; Schuh, A; Krishnamoorthy, G; Wang, H; Amin, RS; Dumoulin, CL; Woods, JC; Bates, AJ. Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry. Editor, Sznitman J. PloS one. 2021; 16:e0256460.

Sun, F; Wang, G; Pradhan, A; Xu, K; Gomez-Arroyo, J; Zhang, Y; Kalin, GT; Deng, Z; Vagnozzi, RJ; He, H; Woods, JC; Kalin, TV; Molkentin, JD; Kalinichenko, VV. Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia. Circulation. 2021; 144:539-555.

Willmering, MM; Cleveland, ZI; Walkup, LL; Woods, JC. Removal of off-resonance xenon gas artifacts in pulmonary gas-transfer MRI. Magnetic Resonance in Medicine. 2021; 86:907-915.

Trisno, SL; Higano, NS; Kechele, D; Nasr, T; Chung, W; Zorn, AM; Woods, JC; Wells, JM; Kingma, PS. Case Report: Esophageal Bronchus in a Neonate, With Image, Histological, and Molecular Analysis. Frontiers in Pediatrics. 2021; 9:707822.

Moutafidis, D; Gavra, M; Golfinopoulos, S; Oikonomopoulou, C; Kitra, V; Woods, JC; Kaditis, AG. Lung hyperinflation quantitated by chest CT in children with bronchiolitis obliterans syndrome following allogeneic hematopoietic cell transplantation. Clinical Imaging. 2021; 75:97-104.

Hahn, AD; Malkus, A; Kammerman, J; Higano, N; Walkup, LL; Woods, J; Fain, SB. Effects of neonatal lung abnormalities on parenchymal R2 * estimates. Journal of Magnetic Resonance Imaging. 2021; 53:1853-1861.

Gandhi, DB; Rice, A; Gunatilaka, CC; Higano, NS; Fleck, RJ; de Alarcon, A; Hart, CK; Kuo, IC; Amin, RS; Woods, JC; Hysinger, EB; Bates, AJ. Quantitative Evaluation of Subglottic Stenosis Using Ultrashort Echo Time MRI in a Rabbit Model. The Laryngoscope. 2021; 131:E1971-E1979.

Lin, NY; Roach, DJ; Willmering, MM; Walkup, LL; Hossain, MM; Desirazu, P; Cleveland, ZI; Guilbert, TW; Woods, JC. 129Xe MRI as a measure of clinical disease severity for pediatric asthma. Journal of Allergy and Clinical Immunology. 2021; 147:2146-2153.e1.

Dournes, G; Walkup, LL; Benlala, I; Willmering, MM; Macey, J; Bui, S; Laurent, F; Woods, JC. The Clinical Use of Lung MRI in Cystic Fibrosis: What, Now, How?. Chest. 2021; 159:2205-2217.

Stecker, IR; Freeman, MS; Sitaraman, S; Hall, CS; Niedbalski, PJ; Hendricks, AJ; Martin, EP; Weaver, TE; Cleveland, ZI. Preclinical MRI to Quantify Pulmonary Disease Severity and Trajectories in Poorly Characterized Mouse Models: A Pedagogical Example Using Data from Novel Transgenic Models of Lung Fibrosis. Journal of Magnetic Resonance Open. 2021; 6-7:100013.

Pennati, F; Walkup, LL; Chhabra, A; Towe, C; Myers, K; Aliverti, A; Woods, JC. Quantitative inspiratory-expiratory chest CT to evaluate pulmonary involvement in pediatric hematopoietic stem-cell transplantation patients. Pediatric Pulmonology. 2021; 56:1026-1035.

Willmering, MM; Roach, DJ; Kramer, EL; Walkup, LL; Cleveland, ZI; Woods, JC. Sensitive structural and functional measurements and 1-year pulmonary outcomes in pediatric cystic fibrosis. Journal of Cystic Fibrosis. 2021; 20:533-539.

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Yang, MM; Higano, NS; Gunatilaka, CC; Hysinger, EB; Amin, RS; Woods, JC; Bates, AJ. Subglottic Stenosis Position Affects Work of Breathing. The Laryngoscope. 2021; 131:E1220-E1226.

Niedbalski, PJ; Cochran, AS; Freeman, MS; Guo, J; Fugate, EM; Davis, CB; Dahlke, J; Quirk, JD; Varisco, BM; Woods, JC; Cleveland, ZI. Validating in vivo hyperpolarized 129 Xe diffusion MRI and diffusion morphometry in the mouse lung. Magnetic Resonance in Medicine. 2021; 85:2160-2173.

Niedbalski, PJ; Cleveland, ZI. Improved preclinical hyperpolarized 129 Xe ventilation imaging with constant flip angle 3D radial golden means acquisition and keyhole reconstruction. NMR in Biomedicine. 2021; 34:e4464.

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Higano, NS; Thomen, RP; Quirk, JD; Huyck, HL; Hahn, AD; Fain, SB; Pryhuber, GS; Woods, JC. Alveolar Airspace Size in Healthy and Diseased Infant Lungs Measured via Hyperpolarized 3He Gas Diffusion Magnetic Resonance Imaging. Neonatology: foetal and neonatal research. 2021; 117:704-712.

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