Zingarelli Lab

Publications

Williams, JG; Whitney, JE; Weiss, SL; Varisco, BM; Yehya, N; Atreya, MR. Derivation and Validation of a Clinical and Endothelial Biomarker Risk Model to Predict Persistent Pediatric Sepsis-Associated Acute Respiratory Dysfunction. 2025; 3:100120.

Zingarelli, B. SHOCK SYNOPSIS FEBRUARY 2025. Shock. 2025; 63:179-181.

Devine, AJ; Smith, NJ; Joshi, R; Brooks-Patton, B; Dunham, J; Varisco, AN; Goodman, EM; Fan, Q; Zingarelli, B; Varisco, BM. KF4 Anti-Chymotrypsin-like Elastase 1 Antibody and Purified Alpha-1 Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine Alpha-1 Antitrypsin Deficiency. Chronic obstructive pulmonary diseases (Miami, Fla.). 2025; 12:12-22.

Atreya, MR; Huang, M; Moore, AR; Zheng, H; Hasin-Brumshtein, Y; Fitzgerald, JC; Weiss, SL; Cvijanovich, NZ; Bigham, MT; Jain, PN; Sweeney, TE; Khatri, P; Sanchez-Pinto, LN; Kamaleswaran, R. Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes. Critical Care (UK). 2024; 28:246.

Amman, AM; Wolfe, V; Piraino, G; Ziady, A; Zingarelli, B. Humanin-G Ameliorates Hemorrhage-Induced Acute Lung Injury in Mice Through AMPKα1-Dependent and -Independent Mechanisms. Biomedicines. 2024; 12:2615.

Stanski, NL; Zhang, B; Cvijanovich, NZ; Fitzgerald, JC; Bigham, MT; Jain, PN; Schwarz, AJ; Lutfi, R; Allen, GL; Thomas, NJ; Zingarelli, B; Standage, SW; Kaplan, J; Goldstein, SL. Diagnostic Validation of the Updated Pediatric Sepsis Biomarker Risk II for Acute Kidney Injury Prediction Model in Pediatric Septic Shock. Pediatric Critical Care Medicine. 2024; 25:1005-1016.

Atreya, MR; Piraino, G; Cvijanovich, NZ; Fitzgerald, JC; Weiss, SL; Bigham, MT; Jain, PN; Schwarz, AJ; Lutfi, R; Nowak, J; Thomas, NJ; Baines, T; Haileselassie, B; Zingarelli, B. SERUM HUMANIN IN PEDIATRIC SEPTIC SHOCK-ASSOCIATED MULTIPLE-ORGAN DYSFUNCTION SYNDROME. Shock. 2024; 61:83-88.

Lautz, A; Atreya, M; Zhang, S; Kempton, K; Alder, M; Zingarelli, B. 893: INDUCED PLURIPOTENT STEM CELL-DERIVED MONOCYTE RESPONSE TO RISK-STRATIFIED PEDIATRIC SEPTIC SERUM. Critical Care Medicine. 2024; 52:s419.

Stanski, NL; Basu, RK; Cvijanovich, NZ; Fitzgerald, JC; Bigham, MT; Jain, PN; Schwarz, AJ; Lutfi, R; Thomas, NJ; Baines, T; Standage, SW; Kaplan, J; Chawla, LS; Goldstein, SL. External validation of the modified sepsis renal angina index for prediction of severe acute kidney injury in children with septic shock. Critical Care (UK). 2023; 27:463.

Atreya, MR; Cvijanovich, NZ; Fitzgerald, JC; Weiss, SL; Bigham, MT; Jain, PN; Schwarz, AJ; Lutfi, R; Nowak, J; Thomas, NJ; Quasney, M; Haileselassie, B; Baines, TD; Zingarelli, B. SERUM SOLUBLE ENDOGLIN IN PEDIATRIC SEPTIC SHOCK-ASSOCIATED MULTIPLE ORGAN DYSFUNCTION SYNDROME. Shock. 2023; 60:379-384.

Wagner, ML; Ammann, A; Piraino, G; Wolfe, V; O'Connor, M; Lahni, P; Ziady, A; Zingarelli, B. PROTECTIVE EFFECTS OF HUMANIN-G IN HEMORRHAGIC SHOCK IN FEMALE MICE VIA AMPKα1-INDEPENDENT MECHANISMS. Shock. 2023; 60:64-74.

Davis, X; Williamson, L; Stuck, J; Howell, K; Lahni, P; Piraino, G; Wolfe, V; Mukherjee, R; Sanchez-Gurmaches, J; Zingarelli, B; Kaplan, J. SEX-DEPENDENT EFFECTS OF ADIPOCYTE STAT3 INHIBITION ON THE INFLAMMATORY RESPONSE DURING SEVERE SEPSIS. Shock. 2023; 59:779-790.

Li, P; Wu, Y; Goodwin, AJ; Wolf, B; Halushka, PV; Wang, H; Zingarelli, B; Fan, H. Circulating extracellular vesicles are associated with the clinical outcomes of sepsis. Frontiers in Immunology. 2023; 14:1150564.

Pei, F; Yao, RQ; Ren, C; Bahrami, S; Billiar, TR; Chaudry, IH; Chen, DC; Chen, XL; Cui, N; Fang, XM; Zingarelli, B; Guan, XD; Wu, JF; Yao, YM. Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression. Military Medical Research. 2022; 9:74.

Urban, C; Hayes, HV; Piraino, G; Wolfe, V; Lahni, P; O’Connor, M; Phares, C; Zingarelli, B. Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice. Frontiers in Immunology. 2022; 13:984298.

Odum, JD; Standage, S; Alder, M; Zingarelli, B; Devarajan, P; Wong, HR. Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies. Shock. 2022; 57:687-693.

Hayes, HV; Wolfe, V; O’connor, M; Levinsky, NC; Piraino, G; Zingarelli, B. Deficiency of AMPKα1 Exacerbates Intestinal Injury and Remote Acute Lung Injury in Mesenteric Ischemia and Reperfusion in Mice. International Journal of Molecular Sciences. 2021; 22:9911.

Wang, P; Mu, X; Zhao, H; Li, Y; Wang, L; Wolfe, V; Cui, SN; Wang, X; Peng, T; Zingarelli, B; Wang, C; Fan, GC. Administration of GDF3 Into Septic Mice Improves Survival via Enhancing LXRα-Mediated Macrophage Phagocytosis. Frontiers in Immunology. 2021; 12:647070.

Zingarelli, B. First Do No Harm: A Proposal of an Expert-Guided Framework of Surrogate Humane Endpoints in Preclinical Models of Acute Lung Injury. Critical Care Medicine. 2021; 49:373-375.