Tchieu Lab

Publications

Chang, X; Li, W; Matsui, S; Huynh, C; Erickson, C; Guo, F; Cederquist, GY; Studer, L; Iwafuchi, M; Shillington, A; Chronis, C; Tchieu, J. ZMYND11 functions in bimodal regulation of latent genes and brain-like splicing to safeguard corticogenesis. Nature Communications. 2025; 16(1):9010.

Peter, J; Caldwell, KCN; Mcclain, L; Tchieu, J; Ross, AE; Luo, Y. Inhibition of PTPRS function does not affect the survival or regeneration of dopaminergic neurons but alters synaptic function in the nigrostriatal pathway. Neurobiology of Disease. 2025; 213:107023.

Miao, Y; Pek, NM; Tan, C; Jiang, C; Yu, Z; Iwasawa, K; Shi, M; Kechele, DO; Sundaram, N; Pastrana-Gomez, V; Zorn, AM; Chen, Y-W; Guo, M; Gu, M. Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids. Cell. 2025; 188(16):4295-4313.e27.

Cai, H; Tian, C; Chen, L; Yang, Y; Sun, AX; Mccracken, K; Tchieu, J; Gu, M; Mackie, K; Guo, F. Vascular network-inspired diffusible scaffolds for engineering functional midbrain organoids. Cell Stem Cell. 2025; 32(5):824-837.e5.

Cederquist, GY; Oberst, P; Chang, X; Tchieu, J; Studer, L. Generation of Prefrontal Cortex Neurons from Human Pluripotent Stem Cells Under Chemically Defined Conditions. 2025:37-51.

Tschuck, J; Padmanabhan Nair, V; Galhoz, A; Zaratiegui, C; Tai, H-M; Ciceri, G; Rothenaigner, I; Tchieu, J; Stockwell, BR; Studer, L; Cabianca, DS; Menden, MP; Vincendeau, M; Hadian, K. Suppression of ferroptosis by vitamin A or radical-trapping antioxidants is essential for neuronal development. Nature Communications. 2024; 15(1):7611.

Liu, X; Xin, DE; Zhong, X; Zhao, C; Li, Z; Zhang, L; Dourson, AJ; Lee, L; Mishra, S; Bayat, AE; Jankowski, MP; Barton, SK; He, X; Lu, QR. Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration. Cell. 2024; 187(10):2465-2484.e22.

Gu, L; Cai, H; Chen, L; Gu, M; Tchieu, J; Guo, F. Functional Neural Networks in Human Brain Organoids. BME Frontiers. 2024; 5:0065.

Cai, H; Ao, Z; Tian, C; Wu, Z; Liu, H; Tchieu, J; Gu, M; Mackie, K; Guo, F. Brain organoid reservoir computing for artificial intelligence. Nature Electronics. 2023; 6(12):1032-1039.

Majd, H; Amin, S; Ghazizadeh, Z; Cesiulis, A; Arroyo, E; Lankford, K; Majd, A; Farahvashi, S; Chemel, AK; Okoye, M; Kocsis, JD; Chen, S; Studer, L; Fattahi, F. Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy. Cell Stem Cell. 2023; 30(5):632-647.e10.

Verrall, CE; Patel, S; Travitz, L; Tchieu, J; Dale, RC; Kasparian, NA; Winlaw, DS; Blue, GM. Biological and structural phenotypes associated with neurodevelopmental outcomes in congenital heart disease. Translational Pediatrics. 2023; 12(4):768-786.

Chang, X; Gu, M; Tchieu, J. Harnessing the Power of Stem Cell Models to Study Shared Genetic Variants in Congenital Heart Diseases and Neurodevelopmental Disorders. Cells. 2022; 11(3).