Denson Lab

Publications

Karns, R; Hyams, JS; Boyle, BM; Noe, JD; Jackson, K; Lynch, K; Ewalt, MK; Nasr, A; Aviles, T; Denson, LA; Minar, P. Large-scale proteomics identifies a pretreatment Crohn's disease core proteome and a dynamic signature for anti-TNF response. Inflammatory Bowel Diseases. 2026.

Negi, S; Hashimoto-Hill, S; Waddell, A; Engleman, L; Lutz, M; Rice, T; Denson, LA; Vallance, BA; Azouz, NP; Tessier, PA; Grivennikov, SI; Deshmukh, H; Alenghat, T. Early-life microbiota direct an epithelial S100 program required for neonatal immunity. Science Translational Medicine. 2026; 18(870):eadx6147.

Xue, M; Mcshane, C; Kim, J; Khorasaniha, R; Leibovitzh, H; Shao, J; Chen, R; Jeong, S; Madsen, KL; Griffiths, AM; Turner, D; Armstrong, H; Croitoru, K; Turpin, W. β-Glucan and Inulin Estimated Intake Are Associated With Reduced Risk of Crohn's Disease, Improved Gut Barrier and Systemic Inflammation Markers, and Multi-Omic Signatures in a High-Risk Cohort. Gastroenterology. 2026; 171(4):641-655.

Santucci, NR; Dike, CR; Hellmann, J; Ollberding, NJ; Duan, Q; Minar, P; Denson, LA; Haslam, DB; Castillo, D; Abu-El-Haija, M. Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls. Journal of Pediatric Gastroenterology and Nutrition. 2026; 83(4):728-736.

Li, H; Lu, Z; Denson, N; Pan, W; Smith, J; Murphy, R; Miraldi, ER; Miethke, AG; Dhaliwal, J; Denson, LA; He, L; Dillman, JR. Multi-modal ensemble learning prediction of anti-TNF treatment response in pediatric patients with Crohn's disease using clinical, radiomic, and deep learning MR enterography features. Inflammatory Bowel Diseases. 2026; 32(10):1980-1992.

Nasr, A; Mizuno, T; Irie, K; Dillman, JR; Jackson, K; Lynch, K; Horrell, A; Aviles, T; Chun, K; Yang, J; Boyle, B; Hyams, JS; Noe, J; Denson, LA; Minar, P. Pharmacometric Targets During Anti-TNF Induction and Their Association with Deep Remission in Pediatric Crohn's Disease. Clinical Pharmacokinetics. 2026; 65(9):1353-1365.

Chen, R; Kim, HJ; Bushra, M; Phi Dang, C; Li, Q; Espin-Garcia, O; Huynh, HQ; Jacobson, K; Bitton, A; Panaccione, R; Griffiths, AM; Turpin, W; Croitoru, K; Lee, S-H. Childhood exposure to a sibling with Crohn's disease alters gut microbiome and Crohn's disease susceptibility. Gut. 2026.

Ramos, KN; Langenberg, L; Lake, KE; Hoerth, CA; Luebbering, N; Haslam, DB; Newburg, D; Morrow, AL; Ollberding, NJ; Teusink-Cross, A; Watanabe-Chailland, M; Romick, L; Davies, SM; Khandelwal, P. Human Milk Oligosaccharide (2'-FL) Modifies the Gut Microbiome in Children after Bone Marrow Transplant. Blood. 2026.

Eshleman, EM; Rice, T; Waddell, A; Kumar, S; Didriksen, BJ; Engleman, L; Vidyant, S; Sayed, M; Karns, R; Lim, H-W; Denson, LA; Alenghat, T. Tuft cells protect against intestinal inflammation through histone deacetylase 3. Mucosal Immunology. 2026; 19(4):100356.

Dattilo, TM; Robbertz, AS; Denson, LA; Hommel, KA. A pilot randomized controlled trial of the self-management assistance for recommended treatment inflammatory bowel disease app for adolescents with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 2026; 83(2):291-295.

Reigle, J; Liu, X; Lopez-Nunez, O; Drysdale, E; Qtaish, D; Walters, TD; Mack, D; Boyle, BM; Kugathasan, S; Denson, N; Denson, LA; Griffiths, AM; Siddiqui, I; Dhaliwal, J. Automated Eosinophil Quantification Using Deep Learning to Predict Therapy Escalation in Pediatric Ulcerative Colitis. Clinical and Translational Gastroenterology. 2026; 17(7):e01031.

Bartel, C; Mizuno, T; Karns, R; Irie, K; Jackson, K; Lynch, K; Samuels, A; Hyams, JS; Boyle, B; Kurowski, JA; Chun, K; Yang, J; Denson, LA; Minar, P. Evaluation of pharmacokinetic metrics and pharmacodynamic biomarkers associated with endoscopic healing in pediatric Crohn's disease patients treated with anti-tumor necrosis factor biologics. Crohn's & Colitis 360. 2026; 8(3):otag088.

Leibovitzh, H; Neustaeter, A; Lee, S-H; Xue, M; Espin-Garcia, O; Olivera, PA; Huynh, HQ; Griffiths, AM; Turner, D; Madsen, KL; Panaccione, R; Xu, W; Turpin, W; Croitoru, K. Interleukin23 Receptor Genetic Variants Associate With Crohn's Disease Risk and Microbiome Changes in Healthy First-Degree Relatives. Clinical Gastroenterology and Hepatology. 2026.

Dillman, JR; Rieder, F; Baker, ME; Fletcher, JG; Bruining, DH; Kugathasan, S; Denson, LA. Probable Stricturing in Small Bowel Crohn Disease: In Support of SAR Consensus Recommendations. American Journal of Roentgenology. 2026; 226(5):e2534245.

Braun, T; Levhar, N; Efroni, G; Hadar, R; Levy, DJ; Talan Asher, A; Abu-Saad, K; Ziv, A; Ben-Avraham Shulman, S; Yahalom, A; Eliakim, R; Amir, A; Ben-Horin, S; Haberman, Y. Perturbations of Diet and Gut Signatures Persist During Remission in Crohn's Disease Despite Effective Immune Suppression. Gastroenterology. 2026; 170(5):971-984.

Dike, C; Yang, R; Ke, S; Nasr, A; Varni, JW; Denson, LA; Haslam, D; Papachristou, G; Abu-El-Haija, M. Tu1900 PEDIATRIC ACUTE PANCREATITIS ASSOCIATED GUT DYSBIOSIS IS ASSOCIATED WITH POOR QUALITY OF LIFE SCORES. Gastroenterology. 2026; 170(6):s-2310-s-2311.

Dike, C; Yang, R; Ke, S; Nasr, A; Varni, JW; Denson, LA; Haslam, D; Papachristou, G; Abu-El-Haija, M. Tu1900 PEDIATRIC ACUTE PANCREATITIS ASSOCIATED GUT DYSBIOSIS IS ASSOCIATED WITH POOR QUALITY OF LIFE SCORES. Gastrointestinal Endoscopy. 2026; 103(5):s-2310-s-2311.

Hamza, L; El Sadaney, AO; Baker, ME; Ream, J; Bruining, DH; Rieder, F; Fidler, JL; Denson, LA; Dillman, JR; Fletcher, JG. Missed strictures and penetrating complications on CT and MR enterography in Crohn's disease patients prior to anti-TNF therapy. Abdominal Radiology. 2026; 51(4):1743-1753.

El Sadaney, AO; Baker, ME; Ream, J; Bruining, DH; Rieder, F; Hamza, L; Barlett, DJ; Fidler, JL; Denson, LA; Dillman, JR; Fletcher, JG. Toward eliminating missed important findings in fibrostenosing Crohn's disease at CT and MR enterography. Abdominal Radiology. 2026; 51(3):1157-1168.

Verburgt, CM; Dunn, KA; Bielawski, JP; Otley, AR; Heyman, MB; Sunseri, W; Shouval, DS; Boneh, RS; De Meij, T; Hyams, JS; Denson, LA; Kugathasan, S; Benninga, MA; De Jonge, WJ; Van Limbergen, JE. Timing is Everything: Lessons Learned for Building Microbiome-Based Models in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 2026; 32(3):576-580.

Levhar, N; Hadar, R; Braun, T; Shacham, H; Algavi, Y; Naamneh, R; Efroni, G; Agranovich, B; Abramovich, I; Talan Asher, A; Eliakim, R; Ben-Horin, S; Amir, A; Haberman, Y. Fecal metabolic signals are associated with changes in microbiota and systemic metabolic pathways in Crohn's disease. Scientific Reports. 2026; 16(1):6991.

Haberman, Y; Braun, T; Karns, R; Bartel, CA; Bonkowski, E; Simpson, KF; Walters, TD; Hyams, JS; Liu, T-C; Kugathasan, S; Denson, LA; Vandussen, KL. Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 2026; 32(2):314-327.

Lee, S-H; Lopes, EW; Khalili, H; Croitoru, K; Colombel, J-F; Peter, I. Prediction and Prevention of Inflammatory Bowel Disease: A Call to Action. Gastroenterology. 2026; 170(2):233-239.

Ramos, KN; Langenberg, L; Lake, KE; Hoerth, C; Luebbering, N; Haslam, D; Newburg, D; Morrow, AL; Ollberding, NJ; Teusink, A; Watanabe-Chailland, M; Romick-Rosendale, L; Davies, SM; Khandelwal, P. 2’-Fucosyllactose (Human Milk Oligosaccharide) Reduces Dysbiosis and Acute GI GVHD in Children and Young Adults Following HSCT: A Prospective, Single-Center Phase II Study. Transplantation and Cellular Therapy. 2026; 32(2):s570.

Heekin, S; Lopez-Nunez, O; Smith, J; Denson, N; Denson, L; Miethke, A; Collins, MH; Dillman, J; Miraldi, E; Kofron, JM; Dhaliwal, J; Erdman, L. Implications of Model Loss and Configuration for Sparse Histological Segmentation. In: Machine Learning Methods in Biomedical Field. Springer Nature; 2026:189-217.

Zeky, N; Erdman, L; Brune, H; Sharma, S; Martincevic, I; Denson, LA; Margolis, P; Beck, AF; Dhaliwal, J. Food Insecurity, Diet, and Clinical Outcomes in Pediatric Inflammatory Bowel Disease: The Role of Unprocessed Foods. Gastro Hep Advances. 2026; 5(9):101038.

Abbas-Egbariya, H; Elwahidi, L; Levy, DJ; Braun, T; Levhar, N; Hadar, R; Efroni, G; Granot, M; Leichtmann-Bardogoo, Y; Maoz, BM; Ben-Horin, S; Vandussen, KL; Amir, A; Haberman, Y. Supplementation with endogenous healthy gut metabolites reverses the disruptions of in vitro and ex vivo epithelial functions induced by fecal content from IBD patients. Gut Microbes. 2025; 17(1):2597568.

Dike, CR; Duan, Q; Ahmed, F; Denson, LA; Haslam, D; Minar, P; Ollberding, NJ; Papachristou, GI; Setchell, KDR; Thompson, T; Vitale, DS; Zhao, X; Abu-El-Haija, M. Acute pancreatitis gut dysbiosis persists at 1-year follow-up and is associated with clinical outcomes. Journal of Pediatric Gastroenterology and Nutrition. 2025; 81(3):690-698.

Derinkuyu, BE; Bard, A; Naim, I; Tkach, JA; Denson, LA; Dillman, JR. Comparison of volumetric and linear measurements of intestinal inflammation and treatment response in children with newly diagnosed ileal Crohn disease. European Radiology. 2025; 35(8):5064-5072.

Secchia, S; Beilinson, V; Chen, X; Gucwa, M; Denson, LA; Miraldi, ER; Weirauch, MT; Ikegami, K. Starvation activates ECM-remodeling gene transcription and putative enhancers in fibroblasts despite inducing quiescence. Cell reports. 2025; 44(7):115896.

Ta, AD; Dillman, JR; Ollberding, NJ; Haberman, Y; Baldassano, R; Markowitz, J; Otley, A; Dotson, JL; Pfefferkorn, M; Hyams, JS; Snapper, S; Alazraki, A; Kugathasan, S; Denson, LA. Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study. Pediatric Radiology. 2025; 55(8):1642-1651.

Ginzburg, G; Hornung, L; Denson, L; Shah, AS; Swauger, S; Tatum, J; Tellez, S; Elder, D; Bellin, MD; Abu-El-Haija, M. Islet Autoantibodies and Their Association With β-Cell Function and Diabetes Measures in Children With Acute Recurrent and Chronic Pancreatitis. Diabetes Care. 2025; 48(6):974-981.

Dillman, JR; Tkach, JA; Fletcher, JG; Bruining, DH; Lu, A; Kugathasan, S; Alazraki, AL; Knight-Scott, J; Stidham, RW; Adler, J; Anton, CG; Imbus, RA; Dudley, JA; Denson, LA. Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease. Inflammatory Bowel Diseases. 2025; 31(5):1380-1391.

Ginzburg, G; Hornung, L; Denson, LA; Shah, A; Swauger, S; Tatum, J; Tellez, S; Elder, D; Bellin, M; Abu-El-Haija, M. 1121: ISLET AUTOANTIBODIES ARE ASSOCIATED WITH β CELL FUNCTION AND DIABETES MEASURES IN CHILDREN WITH ACUTE RECURRENT AND CHRONIC PANCREATITIS. Gastroenterology. 2025; 169(1):s-271-s-272.

Haberman, Y; Braun, T; Levhar, N; Efroni, G; Hadar, R; Jessulalevy, D; Asher, AT; Ungar, B; Picard, O; Yablecovitch, D; Kopylov, U; Denson, LA; Eliakim, R; Ben-Horin, S; Amir, A. Su1960: MULTI-OMICS ANALYSIS OF CROHN’S DISEASE TRAJECTORY FROM ACTIVE TO REMISSION REVEALS THAT DURING REMISSION, ALTERED ILEAL ANTI-BACTERIAL EPITHELIAL SIGNALS AND PATHOGENIC MICROBIOME AND METABOLOMICS PERSIST DESPITE NORMALIZING ILEAL IMMUNE SIGNALS. Gastroenterology. 2025; 169(1):s-908-s-909.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Inflammatory Bowel Diseases. 2025; 31(Supplement_1):s59-s60.

Jurickova, I; Dreskin, BW; Angerman, E; Bonkowski, E; Nguyen, J; Villarreal, R; Tominaga, K; Iwasawa, K; Braun, T; Takebe, T; Helmrath, MA; Haberman, Y; Wells, JM; Denson, LA. Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease. Journal of Crohn's and Colitis. 2025; 19(2).

Lee, S-H; Bushra, M; Qiu, L; Griffiths, AM; Turpin, W; Croitoru, K; Lee, S-H; Bushra, M; Qiu, L; Shao, J; Rubin, D; Schultz, M; Siegel, C; Croitoru, K. Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease. Gastroenterology. 2025; 168(2):385-388.e3.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Gastroenterology. 2025; 168(3):s84-s85.

Ziv, YH; Braun, T; Levhar, N; Efroni, G; Hadar, R; Levy, DJ; Asher, AT; Unger, B; Picard, O; Yablecovitch, D; Eliakim, R; Ben-Horin, S; Amir, A; Nucleus, TLMHBHCTIIR. P1314 Multi-omics analysis of Crohn’s Disease trajectory from active to remission reveals that the altered ileal anti-bacterial epithelial signals and pathogenic microbial composition and metabolomics persist despite normalizing ileal immune signals during remission. Journal of Crohn's and Colitis. 2025; 19(Supplement_1):i2365-i2367.

Ahn, J-H; Da Silva Pedrosa, M; Lopez, LR; Tibbs, TN; Jeyachandran, JN; Vignieri, EE; Rothemich, A; Cumming, I; Irmscher, AD; Haswell, CJ; Zamboni, WC; Yu, Y-RA; Ellermann, M; Denson, LA; Arthur, JC. Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn's disease. Cell Host and Microbe. 2025; 33(1):71-88.e9.

Lee, S-H; Turpin, W; Espin-Garcia, O; Xu, W; Croitoru, K. Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study. Gastroenterology. 2025; 168(1):150-153.e4.

Olivera, PA; Martinez-Lozano, H; Leibovitzh, H; Xue, M; Neustaeter, A; Espin-Garcia, O; Xu, W; Madsen, KL; Guttman, DS; Bernstein, CN; Griffiths, AM; Turpin, W; Lee, S-H; Croitoru, K. Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease. Gastroenterology. 2025; 168(1):99-110.e2.

Tominaga, K; Kechele, DO; Sanchez, JG; Vales, S; Jurickova, I; Roman, L; Asai, A; Enriquez, JR; Mccauley, HA; Kishimoto, K; Zorn, AM; Helmrath, MA; Denson, LA; Wells, JM. Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells. Cellular and Molecular Gastroenterology and Hepatology (CMGH). 2025; 19(4):101444.

Zhao, Q; Duck, LW; Killian, JT; Rosenberg, AF; Mannon, PJ; King, RG; Denson, LA; Kugathasan, S; Janoff, EN; Jenmalm, MC; Elson, CO. Crohn's Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes. Gastroenterology. 2024; 167(7):1415-1428.

Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, D; Farrell, P; Nasr, A; Ibrahim, S; Bellin, M; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. The role of pancreatitis risk genes in diabetes development post index admission of acute pancreatitis in children. Pancreatology. 2024; 24:e10-e11.

Uddin, J; Sharma, A; Wu, D; Tomar, S; Ganesan, V; Reichel, PE; Thota, LNR; Cabrera-Silva, RI; Marella, S; Idelman, G; Divanovic, S; Nusrat, A; Weaver, TE; Hogan, SP. STARD7 maintains intestinal epithelial mitochondria architecture, barrier integrity, and protection from colitis. JCI Insight. 2024; 9(22).

Dillman, JR; Tkach, JA; Fletcher, JG; Bruining, DH; Lu, A; Kugathasan, S; Alazraki, AL; Knight-Scott, J; Stidham, RW; Adler, J; Anton, CG; Imbus, RA; Dudley, JA; Denson, LA. MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease. Inflammatory Bowel Diseases. 2024; 30(11):2181-2190.

Debnath, P; Epstein, KN; Kocaoglu, M; Towbin, AJ; Denson, LA; Dillman, JR. Imaging and clinical predictors of surgery in stricturing ileal Crohn's disease: a retrospective study from a large pediatric hospital. Abdominal Radiology. 2024; 49(10):3354-3363.

Alves, VDPV; Mahalingam, N; Tkach, JA; Towbin, AJ; Imbus, R; Denson, LA; Dillman, JR. Prospective characterization of intestinal MRI intravoxel incoherent motion in pediatric and young adult patients with newly diagnosed small bowel Crohn's disease. Abdominal Radiology. 2024; 49(10):3325-3336.

Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, DS; Farrell, P; Nasr, A; Ibrahim, S; Bellin, MD; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children. Clinical Gastroenterology and Hepatology. 2024; 22(10):2033-2043.e2.

Xue, M; Leibovitzh, H; Jingcheng, S; Neustaeter, A; Dong, M; Xu, W; Espin-Garcia, O; Griffiths, AM; Steinhart, AH; Turner, D; Avni-Biron, I; Lee, S-H; Turpin, W; Croitoru, K. Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project. Clinical Gastroenterology and Hepatology. 2024; 22(9):1889-1897.e12.

Ehsan, L; Coomes, D; Kelly, P; Greene, AR; Ali, SA; Mulenga, C; Denno, DM; Vanbuskirk, K; Raghib, MF; Mahfuz, M; Ahmed, T; Sullivan, PB; Moskaluk, CA; Syed, S. Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multicountry analysis. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S41-S50.

Marie, C; Das, S; Coomes, D; Ahmed, T; Ali, SA; Iqbal, J; Kelly, P; Mahfuz, M; Moore, SR; Petri, WA; Tarr, PI; Denson, LA. Duodenal transcriptomics demonstrates signatures of tissue inflammation and immune cell infiltration in children with environmental enteric dysfunction across global centers. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S51-S64.

Jamil, Z; Vanbuskirk, K; Mweetwa, M; Mouksassi, S; Smith, G; Ahmed, T; Chandwe, K; Denno, DM; Fahim, SM; Kelly, P; Marie, C; Moore, SR; Petri, WA; Ali, SA. Anthropometry relationship with duodenal histologic features of children with environmental enteric dysfunction: a multicenter cross-sectional study. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S65-S72.

Denno, DM; Ahmed, S; Ahmed, T; Ali, SA; Amadi, B; Kelly, P; Lawrence, S; Mahfuz, M; Marie, C; Moore, SR; Nataro, JP; Petri, WA; Sullivan, PB; Tarr, PI. The Environmental Enteric Dysfunction Biopsy Initiative (EEDBI) Consortium: mucosal investigations of environmental enteric dysfunction. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S4-S14.

Kelly, P; Vanbuskirk, K; Coomes, D; Mouksassi, S; Smith, G; Jamil, Z; Hossain, MS; Syed, S; Marie, C; Tarr, PI; Tearney, GJ; Raghavan, SS; Moskaluk, CA; Liu, T-C. Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared with United States children. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S15-S30.

Vanbuskirk, K; Mweetwa, M; Kolterman, T; Raghavan, S; Ahmed, T; Ali, SA; Nahar Begum, SK; Besa, E; Denno, DM; Jamil, Z; Petri, WA; Tarr, PI; Sullivan, PB; Moskaluk, CA. Multiplexed immunohistochemical evaluation of small bowel inflammatory and epithelial parameters in environmental enteric dysfunction. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S31-S40.

Briggs, K; Tomar, V; Ollberding, N; Haberman, Y; Bourgonje, AR; Hu, S; Chaaban, L; Sunuwar, L; Weersma, RK; Denson, LA; Melia, JMP. Crohn's Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism. Inflammatory Bowel Diseases. 2024; 30(8):1379-1388.

Zulqarnain, F; Zhao, X; Setchell, KDR; Sharma, Y; Fernandes, P; Srivastava, S; Shrivastava, A; Ehsan, L; Jain, V; Raghavan, S; Brown, DE; Moore, SR; Ali, SA; Syed, S. Machine-learning-based integrative -'omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction. iScience. 2024; 27(6):110013.

Ando, T; Takazawa, I; Spencer, ZT; Ito, R; Tomimori, Y; Mikulski, Z; Matsumoto, K; Ishitani, T; Denson, LA; Kawakami, Y; Kawakami, Y; Kitaura, J; Ahmed, Y; Kawakami, T. Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway. Cells. 2024; 13(11).

Hommel, KA; Noser, AE; Plevinsky, J; Gamwell, K; Denson, LA. Pilot and feasibility of the SMART IBD mobile app to improve self-management in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 2024; 78(6):1273-1278.

Braun, T; Feng, R; Amir, A; Levhar, N; Shacham, H; Mao, R; Hadar, R; Toren, I; Algavi, Y; Abu-Saad, K; Elinav, E; Chen, M; Ben-Horin, S; Haberman, Y. Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort. Nature Communications. 2024; 15(1):3764.

Liu, X; Prasath, S; Siddiqui, I; Walters, TD; Denson, LA; Dhaliwal, J. Machine Learning-Based Prediction of Pediatric Ulcerative Colitis Treatment Response Using Diagnostic Histopathology. Gastroenterology. 2024; 166(5):921-924.e4.

Nasr, A; Mizuno, T; Irie, K; Dillman, J; Jackson, K; Lynch, K; Horrell, A; Chun, KY; Yang, JM; Hyams, JS; Boyle, BM; Noe, JD; Denson, LA; Minar, PP. 958 ATTAINING EARLY ANTI-TNF EXPOSURE TARGETS IS ASSOCIATED WITH IMPROVED RATES OF ENDOSCOPIC HEALING AND TRANSMURAL HEALING IN CHILDREN WITH CROHN'S DISEASE. Gastroenterology. 2024; 166(5):s-226-s-227.

Minar, PP; Karns, R; Lynch, K; Jackson, K; Horrell, A; Boyle, BM; Hyams, JS; Noe, JD; Denson, LA. 748 EXTENSIVE PROTEOMIC ANALYSIS IDENTIFIES A CROHN'S DISEASE CORE PROTEOME AND ANTI-TNF TREATMENT RESPONSE PROFILE FOR CHILDREN WITH CROHN'S DISEASE. Gastroenterology. 2024; 166(5):s-177-s-178.

Briggs, K; Tomar, V; Ollberding, N; Haberman, Y; Bourgonje, AR; Hu, S; Chaaban, L; Sunuwar, L; Weersma, RK; Denson, LA; Melia, JP. Mo1794 CROHN'S DISEASE-ASSOCIATED PATHOGENIC MUTATION IN MANGANESE TRANSPORTER ZIP8 SHIFTS THE ILEAL AND RECTAL MUCOSAL MICROBIOTA IMPLICATING ABERRANT BILE ACID METABOLISM. Gastroenterology. 2024; 166(5):s-1114.

Wang, Z; Song, X; Waitman, LR; Hyams, JS; Denson, LA. Fitness-for-use of Retrospective Multicenter Electronic Health Records to Conduct Outcome Analysis for Pediatric Ulcerative Colitis. Medicine (United Kingdom). 2024; 103(11):e37395.

Dike, CR; Ollberding, NJ; Thompson, T; Kotha, N; Minar, P; Vitale, DS; Lin, TK; Nasr, A; Denson, LA; Haslam, DB; Abu-El-Haija, M. Acute pancreatitis is associated with gut dysbiosis in children. Digestive and Liver Disease. 2024; 56(3):444-450.

Schirmer, M; Stražar, M; Avila-Pacheco, J; Rojas-Tapias, DF; Brown, EM; Temple, E; Deik, A; Bullock, K; Jeanfavre, S; Pierce, K; Hyams, J; Denson, L; Clish, CB; Xavier, RJ. Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course. Cell Host and Microbe. 2024; 32(2):209-226.e7.

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Shih, T; Yusung, S; Gonsky, R; Dutra-Clarke, R; Ziring, D; Rabizadeh, S; Kugathasan, S; Denson, LA; Li, D; Braun, J. Environmental Interaction of Resolved Human Cytomegalovirus Infection With Crohn's Disease Location. Inflammatory Bowel Diseases. 2023; 29(2):328-331.

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Abu-Ata, N; Dillman, JR; Rubin, JM; Collins, MH; Johnson, LA; Imbus, RS; Bonkowski, EL; Denson, LA; Higgins, PDR. Ultrasound shear wave elastography in pediatric stricturing small bowel Crohn disease: correlation with histology and second harmonic imaging microscopy. Pediatric Radiology. 2023; 53(1):34-45.

Dillman, JR; Ata, NA; Towbin, AJ; Anton, CG; Smith, EA; Zhang, B; Imbus, R; Tkach, JA; Denson, LA. The Simplified MR Index of Activity Score in Pediatric Small-Bowel Crohn Disease: An Interreader Agreement and Responsiveness Study. American Journal of Roentgenology. 2023; 220(1):126-133.

Hommel, KA; Ramsey, RR; Gray, WN; Denson, LA. Digital Therapeutic Self-Management Intervention in Adolescents With Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. 2023; 76(1):38-42.

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Dillman, JR; Tkach, JA; Imbus, R; Towbin, AJ; Denson, LA. MRI-Based Characterization of Intestinal Motility in Children and Young Adults With Newly Diagnosed Ileal Crohn Disease Treated by Biologic Therapy: A Controlled Prospective Study. American Journal of Roentgenology. 2022; 219(4):655-664.

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Ata, NA; Dillman, JR; Gandhi, D; Dudley, JA; Trout, AT; Imbus, R; Towbin, AJ; Denson, LA; Tkach, JA. Velocity-Encoded Phase-Contrast MRI for Measuring Mesenteric Blood Flow in Patients With Newly Diagnosed Small-Bowel Crohn Disease. American Journal of Roentgenology. 2022; 219(1):132-141.

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Jurickova, I; Huron, A; Angerman, E; Bonkowski, E; Jegga, A; Haberman, Y; Denson, L. EICOSATETRAYNOIC ACID REGULATES MITOCHONDRIAL AND EXTRA-CELLULAR MATRIX GENE EXPRESSION AND TISSUE STIFFNESS IN A HUMAN INTESTINAL ORGANOID MODEL OF ILEAL CROHN’S DISEASE. Gastroenterology. 2022; 162(3):s62-s63.

Colman, R; Mizuno, T; Hyams, J; Noe, J; Boyle, B; Denson, L; Vinks, A; Minar, P. REAL-WORLD VEDOLIZUMAB PHARMACOKINETIC STUDY IN CHILDREN IDENTIFIES TWO NOVEL BIOMARKERS OF DRUG CLEARANCE. Gastroenterology. 2022; 162(3):s100.

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