Denson Lab

Publications

Levhar, N; Hadar, R; Braun, T; Shacham, H; Algavi, Y; Naamneh, R; Efroni, G; Agranovich, B; Abramovich, I; Talan Asher, A; Eliakim, R; Ben-Horin, S; Amir, A; Haberman, Y. Fecal metabolic signals are associated with changes in microbiota and systemic metabolic pathways in Crohn's disease. Scientific Reports. 2026.

Haberman, Y; Braun, T; Karns, R; Bartel, CA; Bonkowski, E; Simpson, KF; Walters, TD; Hyams, JS; Liu, T-C; Kugathasan, S; Denson, LA; Vandussen, KL. Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 2026; 32(2):314-327.

Lee, S-H; Lopes, EW; Khalili, H; Croitoru, K; Colombel, J-F; Peter, I. Prediction and Prevention of Inflammatory Bowel Disease: A Call to Action. Gastroenterology. 2026; 170(2):233-239.

Verburgt, CM; Dunn, KA; Bielawski, JP; Otley, AR; Heyman, MB; Sunseri, W; Shouval, DS; Boneh, RS; De Meij, T; Hyams, JS; Denson, LA; Kugathasan, S; Benninga, MA; De Jonge, WJ; Van Limbergen, JE. Timing is Everything: Lessons Learned for Building Microbiome-Based Models in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. 2026.

Dillman, JR; Rieder, F; Baker, ME; Fletcher, JG; Bruining, DH; Kugathasan, S; Denson, LA. Probable Stricturing in Small Bowel Crohn Disease: In Support of SAR Consensus Recommendations. American Journal of Roentgenology. 2026.

Heekin, S; Lopez-Nunez, O; Smith, J; Denson, N; Denson, L; Miethke, A; Collins, MH; Dillman, J; Miraldi, E; Kofron, JM; Dhaliwal, J; Erdman, L. Implications of Model Loss and Configuration for Sparse Histological Segmentation. In: Machine Learning Methods in Biomedical Field. Springer Nature; 2026:189-217.

Abbas-Egbariya, H; Elwahidi, L; Levy, DJ; Braun, T; Levhar, N; Hadar, R; Efroni, G; Granot, M; Leichtmann-Bardogoo, Y; Maoz, BM; Ben-Horin, S; Vandussen, KL; Amir, A; Haberman, Y. Supplementation with endogenous healthy gut metabolites reverses the disruptions of in vitro and ex vivo epithelial functions induced by fecal content from IBD patients. Gut Microbes. 2025; 17(1):2597568.

El Sadaney, AO; Baker, ME; Ream, J; Bruining, DH; Rieder, F; Hamza, L; Barlett, DJ; Fidler, JL; Denson, LA; Dillman, JR; Fletcher, JG. Toward eliminating missed important findings in fibrostenosing Crohn's disease at CT and MR enterography. Abdominal Radiology. 2025.

Hamza, L; El Sadaney, AO; Baker, ME; Ream, J; Bruining, DH; Rieder, F; Fidler, JL; Denson, LA; Dillman, JR; Fletcher, JG. Missed strictures and penetrating complications on CT and MR enterography in Crohn's disease patients prior to anti-TNF therapy. Abdominal Radiology. 2025.

Dike, CR; Duan, Q; Ahmed, F; Denson, LA; Haslam, D; Minar, P; Ollberding, NJ; Papachristou, GI; Setchell, KDR; Thompson, T; Vitale, DS; Zhao, X; Abu-El-Haija, M. Acute pancreatitis gut dysbiosis persists at 1-year follow-up and is associated with clinical outcomes. Journal of Pediatric Gastroenterology and Nutrition. 2025; 81(3):690-698.

Derinkuyu, BE; Bard, A; Naim, I; Tkach, JA; Denson, LA; Dillman, JR. Comparison of volumetric and linear measurements of intestinal inflammation and treatment response in children with newly diagnosed ileal Crohn disease. European Radiology. 2025; 35(8):5064-5072.

Secchia, S; Beilinson, V; Chen, X; Gucwa, M; Denson, LA; Miraldi, ER; Weirauch, MT; Ikegami, K. Starvation activates ECM-remodeling gene transcription and putative enhancers in fibroblasts despite inducing quiescence. Cell reports. 2025; 44(7):115896.

Ta, AD; Dillman, JR; Ollberding, NJ; Haberman, Y; Baldassano, R; Markowitz, J; Otley, A; Dotson, JL; Pfefferkorn, M; Hyams, JS; Snapper, S; Alazraki, A; Kugathasan, S; Denson, LA. Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study. Pediatric Radiology. 2025; 55(8):1642-1651.

Ginzburg, G; Hornung, L; Denson, L; Shah, AS; Swauger, S; Tatum, J; Tellez, S; Elder, D; Bellin, MD; Abu-El-Haija, M. Islet Autoantibodies and Their Association With β-Cell Function and Diabetes Measures in Children With Acute Recurrent and Chronic Pancreatitis. Diabetes Care. 2025; 48(6):974-981.

Dillman, JR; Tkach, JA; Fletcher, JG; Bruining, DH; Lu, A; Kugathasan, S; Alazraki, AL; Knight-Scott, J; Stidham, RW; Adler, J; Anton, CG; Imbus, RA; Dudley, JA; Denson, LA. Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease. Inflammatory Bowel Diseases. 2025; 31(5):1380-1391.

Ginzburg, G; Hornung, L; Denson, LA; Shah, A; Swauger, S; Tatum, J; Tellez, S; Elder, D; Bellin, M; Abu-El-Haija, M. 1121: ISLET AUTOANTIBODIES ARE ASSOCIATED WITH β CELL FUNCTION AND DIABETES MEASURES IN CHILDREN WITH ACUTE RECURRENT AND CHRONIC PANCREATITIS. Gastroenterology. 2025; 169(1):s-271-s-272.

Haberman, Y; Braun, T; Levhar, N; Efroni, G; Hadar, R; Jessulalevy, D; Asher, AT; Ungar, B; Picard, O; Yablecovitch, D; Kopylov, U; Denson, LA; Eliakim, R; Ben-Horin, S; Amir, A. Su1960: MULTI-OMICS ANALYSIS OF CROHN’S DISEASE TRAJECTORY FROM ACTIVE TO REMISSION REVEALS THAT DURING REMISSION, ALTERED ILEAL ANTI-BACTERIAL EPITHELIAL SIGNALS AND PATHOGENIC MICROBIOME AND METABOLOMICS PERSIST DESPITE NORMALIZING ILEAL IMMUNE SIGNALS. Gastroenterology. 2025; 169(1):s-908-s-909.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Inflammatory Bowel Diseases. 2025; 31(Supplement_1):s59-s60.

Jurickova, I; Dreskin, BW; Angerman, E; Bonkowski, E; Nguyen, J; Villarreal, R; Tominaga, K; Iwasawa, K; Braun, T; Takebe, T; Helmrath, MA; Haberman, Y; Wells, JM; Denson, LA. Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease. Journal of Crohn's and Colitis. 2025; 19(2).

Lee, S-H; Bushra, M; Qiu, L; Griffiths, AM; Turpin, W; Croitoru, K; Lee, S-H; Bushra, M; Qiu, L; Shao, J; Rubin, D; Schultz, M; Siegel, C; Croitoru, K. Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease. Gastroenterology. 2025; 168(2):385-388.e3.

Bartel, C; Mizuno, T; Irie, K; Samuels, A; Lynch, K; Jackson, K; Hyams, J; Boyle, B; Saeed, S; Kurowski, J; Noe, J; Chun, K; Yang, J; Denson, L; Minar, P. AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN’S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS. Gastroenterology. 2025; 168(3):s84-s85.

Ziv, YH; Braun, T; Levhar, N; Efroni, G; Hadar, R; Levy, DJ; Asher, AT; Unger, B; Picard, O; Yablecovitch, D; Eliakim, R; Ben-Horin, S; Amir, A; Nucleus, TLMHBHCTIIR. P1314 Multi-omics analysis of Crohn’s Disease trajectory from active to remission reveals that the altered ileal anti-bacterial epithelial signals and pathogenic microbial composition and metabolomics persist despite normalizing ileal immune signals during remission. Journal of Crohn's and Colitis. 2025; 19(Supplement_1):i2365-i2367.

Ahn, J-H; Da Silva Pedrosa, M; Lopez, LR; Tibbs, TN; Jeyachandran, JN; Vignieri, EE; Rothemich, A; Cumming, I; Irmscher, AD; Haswell, CJ; Zamboni, WC; Yu, Y-RA; Ellermann, M; Denson, LA; Arthur, JC. Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn's disease. Cell Host and Microbe. 2025; 33(1):71-88.e9.

Lee, S-H; Turpin, W; Espin-Garcia, O; Xu, W; Croitoru, K. Development and Validation of an Integrative Risk Score for Future Risk of Crohn's Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study. Gastroenterology. 2025; 168(1):150-153.e4.

Olivera, PA; Martinez-Lozano, H; Leibovitzh, H; Xue, M; Neustaeter, A; Espin-Garcia, O; Xu, W; Madsen, KL; Guttman, DS; Bernstein, CN; Griffiths, AM; Turpin, W; Lee, S-H; Croitoru, K. Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn's Disease. Gastroenterology. 2025; 168(1):99-110.e2.

Tominaga, K; Kechele, DO; Sanchez, JG; Vales, S; Jurickova, I; Roman, L; Asai, A; Enriquez, JR; Mccauley, HA; Kishimoto, K; Zorn, AM; Helmrath, MA; Denson, LA; Wells, JM. Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells. Cellular and Molecular Gastroenterology and Hepatology (CMGH). 2025; 19(4):101444.

Zhao, Q; Duck, LW; Killian, JT; Rosenberg, AF; Mannon, PJ; King, RG; Denson, LA; Kugathasan, S; Janoff, EN; Jenmalm, MC; Elson, CO. Crohn's Patients and Healthy Infants Share Immunodominant B Cell Response to Commensal Flagellin Peptide Epitopes. Gastroenterology. 2024; 167(7):1415-1428.

Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, D; Farrell, P; Nasr, A; Ibrahim, S; Bellin, M; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. The role of pancreatitis risk genes in diabetes development post index admission of acute pancreatitis in children. Pancreatology. 2024; 24:e10-e11.

Uddin, J; Sharma, A; Wu, D; Tomar, S; Ganesan, V; Reichel, PE; Thota, LNR; Cabrera-Silva, RI; Marella, S; Idelman, G; Divanovic, S; Nusrat, A; Weaver, TE; Hogan, SP. STARD7 maintains intestinal epithelial mitochondria architecture, barrier integrity, and protection from colitis. JCI Insight. 2024; 9(22).

Dillman, JR; Tkach, JA; Fletcher, JG; Bruining, DH; Lu, A; Kugathasan, S; Alazraki, AL; Knight-Scott, J; Stidham, RW; Adler, J; Anton, CG; Imbus, RA; Dudley, JA; Denson, LA. MRI and Blood-based Biomarkers Are Associated With Surgery in Children and Adults With Ileal Crohn's Disease. Inflammatory Bowel Diseases. 2024; 30(11):2181-2190.

Debnath, P; Epstein, KN; Kocaoglu, M; Towbin, AJ; Denson, LA; Dillman, JR. Imaging and clinical predictors of surgery in stricturing ileal Crohn's disease: a retrospective study from a large pediatric hospital. Abdominal Radiology. 2024; 49(10):3354-3363.

Alves, VDPV; Mahalingam, N; Tkach, JA; Towbin, AJ; Imbus, R; Denson, LA; Dillman, JR. Prospective characterization of intestinal MRI intravoxel incoherent motion in pediatric and young adult patients with newly diagnosed small bowel Crohn's disease. Abdominal Radiology. 2024; 49(10):3325-3336.

Abu-El-Haija, M; Zhang, W; Karns, R; Ginzburg, G; Vitale, DS; Farrell, P; Nasr, A; Ibrahim, S; Bellin, MD; Thompson, T; Garlapally, V; Woo, JG; Husain, SZ; Denson, LA. The Role of Pancreatitis Risk Genes in Endocrine Insufficiency Development After Acute Pancreatitis in Children. Clinical Gastroenterology and Hepatology. 2024; 22(10):2033-2043.e2.

Xue, M; Leibovitzh, H; Jingcheng, S; Neustaeter, A; Dong, M; Xu, W; Espin-Garcia, O; Griffiths, AM; Steinhart, AH; Turner, D; Avni-Biron, I; Lee, S-H; Turpin, W; Croitoru, K. Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project. Clinical Gastroenterology and Hepatology. 2024; 22(9):1889-1897.e12.

Ehsan, L; Coomes, D; Kelly, P; Greene, AR; Ali, SA; Mulenga, C; Denno, DM; Vanbuskirk, K; Raghib, MF; Mahfuz, M; Ahmed, T; Sullivan, PB; Moskaluk, CA; Syed, S. Duodenal quantitative mucosal morphometry in children with environmental enteric dysfunction: a cross-sectional multicountry analysis. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S41-S50.

Marie, C; Das, S; Coomes, D; Ahmed, T; Ali, SA; Iqbal, J; Kelly, P; Mahfuz, M; Moore, SR; Petri, WA; Tarr, PI; Denson, LA. Duodenal transcriptomics demonstrates signatures of tissue inflammation and immune cell infiltration in children with environmental enteric dysfunction across global centers. American Journal of Clinical Nutrition. 2024; 120 Suppl 1(Suppl 1):S51-S64.

Jamil, Z; Vanbuskirk, K; Mweetwa, M; Mouksassi, S; Smith, G; Ahmed, T; Chandwe, K; Denno, DM; Fahim, SM; Kelly, P; Marie, C; Moore, SR; Petri, WA; Ali, SA. Anthropometry relationship with duodenal histologic features of children with environmental enteric dysfunction: a multicenter cross-sectional study. American Journal of Clinical Nutrition. 2024; 120 Suppl 1:S65-S72.

Denno, DM; Ahmed, S; Ahmed, T; Ali, SA; Amadi, B; Kelly, P; Lawrence, S; Mahfuz, M; Marie, C; Moore, SR; Nataro, JP; Petri, WA; Sullivan, PB; Tarr, PI. The Environmental Enteric Dysfunction Biopsy Initiative (EEDBI) Consortium: mucosal investigations of environmental enteric dysfunction. American Journal of Clinical Nutrition. 2024; 120 Suppl 1:S4-S14.

Kelly, P; Vanbuskirk, K; Coomes, D; Mouksassi, S; Smith, G; Jamil, Z; Hossain, MS; Syed, S; Marie, C; Tarr, PI; Tearney, GJ; Raghavan, SS; Moskaluk, CA; Liu, T-C. Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared with United States children. American Journal of Clinical Nutrition. 2024; 120 Suppl 1:S15-S30.

Vanbuskirk, K; Mweetwa, M; Kolterman, T; Raghavan, S; Ahmed, T; Ali, SA; Nahar Begum, SK; Besa, E; Denno, DM; Jamil, Z; Petri, WA; Tarr, PI; Sullivan, PB; Moskaluk, CA. Multiplexed immunohistochemical evaluation of small bowel inflammatory and epithelial parameters in environmental enteric dysfunction. American Journal of Clinical Nutrition. 2024; 120 Suppl 1:S31-S40.

Briggs, K; Tomar, V; Ollberding, N; Haberman, Y; Bourgonje, AR; Hu, S; Chaaban, L; Sunuwar, L; Weersma, RK; Denson, LA; Melia, JMP. Crohn's Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism. Inflammatory Bowel Diseases. 2024; 30(8):1379-1388.

Zulqarnain, F; Zhao, X; Setchell, KDR; Sharma, Y; Fernandes, P; Srivastava, S; Shrivastava, A; Ehsan, L; Jain, V; Raghavan, S; Brown, DE; Moore, SR; Ali, SA; Syed, S. Machine-learning-based integrative -'omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction. iScience. 2024; 27(6):110013.

Ando, T; Takazawa, I; Spencer, ZT; Ito, R; Tomimori, Y; Mikulski, Z; Matsumoto, K; Ishitani, T; Denson, LA; Kawakami, Y; Kawakami, Y; Kitaura, J; Ahmed, Y; Kawakami, T. Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway. Cells. 2024; 13(11).

Hommel, KA; Noser, AE; Plevinsky, J; Gamwell, K; Denson, LA. Pilot and feasibility of the SMART IBD mobile app to improve self-management in pediatric inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 2024; 78(6):1273-1278.

Braun, T; Feng, R; Amir, A; Levhar, N; Shacham, H; Mao, R; Hadar, R; Toren, I; Algavi, Y; Abu-Saad, K; Elinav, E; Chen, M; Ben-Horin, S; Haberman, Y. Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort. Nature Communications. 2024; 15(1):3764.

Liu, X; Prasath, S; Siddiqui, I; Walters, TD; Denson, LA; Dhaliwal, J. Machine Learning-Based Prediction of Pediatric Ulcerative Colitis Treatment Response Using Diagnostic Histopathology. Gastroenterology. 2024; 166(5):921-924.e4.

Nasr, A; Mizuno, T; Irie, K; Dillman, J; Jackson, K; Lynch, K; Horrell, A; Chun, KY; Yang, JM; Hyams, JS; Boyle, BM; Noe, JD; Denson, LA; Minar, PP. 958 ATTAINING EARLY ANTI-TNF EXPOSURE TARGETS IS ASSOCIATED WITH IMPROVED RATES OF ENDOSCOPIC HEALING AND TRANSMURAL HEALING IN CHILDREN WITH CROHN'S DISEASE. Gastroenterology. 2024; 166(5):s-226-s-227.

Minar, PP; Karns, R; Lynch, K; Jackson, K; Horrell, A; Boyle, BM; Hyams, JS; Noe, JD; Denson, LA. 748 EXTENSIVE PROTEOMIC ANALYSIS IDENTIFIES A CROHN'S DISEASE CORE PROTEOME AND ANTI-TNF TREATMENT RESPONSE PROFILE FOR CHILDREN WITH CROHN'S DISEASE. Gastroenterology. 2024; 166(5):s-177-s-178.

Briggs, K; Tomar, V; Ollberding, N; Haberman, Y; Bourgonje, AR; Hu, S; Chaaban, L; Sunuwar, L; Weersma, RK; Denson, LA; Melia, JP. Mo1794 CROHN'S DISEASE-ASSOCIATED PATHOGENIC MUTATION IN MANGANESE TRANSPORTER ZIP8 SHIFTS THE ILEAL AND RECTAL MUCOSAL MICROBIOTA IMPLICATING ABERRANT BILE ACID METABOLISM. Gastroenterology. 2024; 166(5):s-1114.

Wang, Z; Song, X; Waitman, LR; Hyams, JS; Denson, LA. Fitness-for-use of Retrospective Multicenter Electronic Health Records to Conduct Outcome Analysis for Pediatric Ulcerative Colitis. Medicine (United Kingdom). 2024; 103(11):e37395.

Dike, CR; Ollberding, NJ; Thompson, T; Kotha, N; Minar, P; Vitale, DS; Lin, TK; Nasr, A; Denson, LA; Haslam, DB; Abu-El-Haija, M. Acute pancreatitis is associated with gut dysbiosis in children. Digestive and Liver Disease. 2024; 56(3):444-450.

Schirmer, M; Stražar, M; Avila-Pacheco, J; Rojas-Tapias, DF; Brown, EM; Temple, E; Deik, A; Bullock, K; Jeanfavre, S; Pierce, K; Hyams, J; Denson, L; Clish, CB; Xavier, RJ. Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course. Cell Host and Microbe. 2024; 32(2):209-226.e7.

Eshleman, EM; Rice, T; Potter, C; Waddell, A; Hashimoto-Hill, S; Woo, V; Field, S; Engleman, L; Lim, H-W; Schumacher, MA; Frey, MR; Denson, LA; Finkelman, FD; Alenghat, T. Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity. Immunity. 2024; 57(2):319-332.e6.

Geem, D; Hercules, D; Pelia, RS; Venkateswaran, S; Griffiths, A; Noe, JD; Dotson, JL; Snapper, S; Rabizadeh, S; Rosh, JR; Sharma, G; Denson, LA; Hyams, JS; Kugathasan, S. Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization. Clinical Gastroenterology and Hepatology. 2024; 22(2):368-376.e4.

Dillman, J; Fletcher, JG; Bruining, D; Kugathasan, S; Stidham, R; Adler, J; Tkach, J; Alazraki, A; Knight-Scott, J; Lu, A; Anton, C; Imbus, R; Dudley, J; Denson, L. MRI AND BLOOD-BASED BIOMARKERS ASSOCIATED WITH SURGICAL MANAGEMENT IN CHILDREN AND ADULTS WITH SMALL BOWEL CROHN'S DISEASE. Gastroenterology. 2024; 166(3):s19-s20.

Ramos, KN; Lake, KE; Hoerth, C; Langenberg, L; Luebbering, N; Haslam, D; Newburg, D; Morrow, AL; Ollberding, NJ; Denson, LA; Watanabe-Chailland, M; Romick-Rosendale, L; Davies, SM; Khandelwal, P. Administration of Human Milk Oligosaccharide (2′-fucosyllactose) Reduces Dysbiosis and Increases Short Chain Fatty Acids in Children and Young Adults Following HSCT: A Prospective, Single-Center Study. Transplantation and Cellular Therapy. 2024; 30(2):s16.

Dillman, J; Fletcher, JG; Bruining, D; Kugathasan, S; Stidham, R; Adler, J; Tkach, J; Alazraki, A; Knight-Scott, J; Lu, A; Anton, C; Imbus, R; Dudley, J; Denson, L. MRI AND BLOOD-BASED BIOMARKERS ASSOCIATED WITH SURGICAL MANAGEMENT IN CHILDREN AND ADULTS WITH SMALL BOWEL CROHN'S DISEASE. Inflammatory Bowel Diseases. 2024; 30(Supplement_1):s14-s15.

Derinkuyu, BE; Bard, A; Naim, I; Tkach, JA; Denson, LA; Dillman, JR. P067 Volumetric Assessment of Treatment Response in Newly Diagnosed Crohn Disease: A Pilot Study. Journal of Crohn's and Colitis. 2024; 18(Supplement_1):i333-i333.

Zhang, D; Tang, W; Niu, H; Tse, W; Ruan, H-B; Dolznig, H; Knösel, T; Karl-Heinz, F; Themanns, M; Wang, J; Kenner, L; Moriggl, R; Zheng, Y; Han, X. Monogenic deficiency in murine intestinal Cdc42 leads to mucosal inflammation that induces crypt dysplasia. Genes and Diseases. 2024; 11(1):413-429.

Liu, RX; Li, H; Towbin, AJ; Ata, NA; Smith, EA; Tkach, JA; Denson, LA; He, L; Dillman, JR. Machine Learning Diagnosis of Small-Bowel Crohn Disease Using T2-Weighted MRI Radiomic and Clinical Data. American Journal of Roentgenology. 2024; 222(1):e2329812.

Roberts, CM; Plevinsky, JM; Gamwell, KL; Noser, AE; Denson, LA; Hommel, KA. Self-Management assistance for recommended treatment (SMART) IBD app randomized control trial in adolescents with IBD: Design and methodology. Health Care Transitions. 2024; 2:100031.

Wang, Z; Nie, J; Song, X; Denson, LA; Hyams, JS. A comparison of Bayesian and frequentist approaches to incorporating clinical and biological information for the prediction of response to standardized pediatric colitis therapy. PLoS ONE. 2024; 19(3):e0295814.

Romo, MV; Acharya, K; Shelman, NR; Minar, P; Denson, LA; Softic, S. De Novo Crohn's Disease Diagnosed in the Setting of Acute SARS-Cov-2 Infection Requiring Escalation of Infliximab Therapy Guided by Personalized Pharmacokinetics. J Pediatr Perinatol Child Health. 2024; 8(1):1-4.

Velez Lopez, A; Waddell, A; Antonacci, S; Castillo, D; Santucci, N; Ollberding, NJ; Eshleman, EM; Denson, LA; Alenghat, T. Microbiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids. Neurogastroenterology and Motility. 2023; 35(12):e14681.

Sosnovski, KE; Braun, T; Amir, A; Benshoshan, M; Abbas-Egbariya, H; Ben-Yishay, R; Anafi, L; Avivi, C; Barshack, I; Denson, LA; Haberman, Y. Reduced LHFPL3-AS2 lncRNA expression is linked to altered epithelial polarity and proliferation, and to ileal ulceration in Crohn disease. Scientific Reports. 2023; 13(1):20513.

Dike, C; Ollberding, N; Thompson, T; Kotha, N; Minar, P; Vitale, D; Lin, T; Nasr, A; Denson, L; Haslam, D; Abu-El-Haija, M. Acute pancreatitis is associated with gut dysbiosis in children. Pancreatology. 2023; 23:e3-e4.

Zulqarnain, F; Zhao, X; Setchell, K; Sharma, Y; Fernandes, P; Srivastava, A; Ehsan, L; Jain, V; Raghavan, SS; Moskaluk, C; Brown, DE; Moore, SR; Ali, SA; Syed, S. Integrative –‘Omics and Machine-Learning-Based Image Analyses of Environmental Enteric Dysfunction Reveal an Immunologic and Metabolic Pathogenesis of Intestinal Failure. . 2023.

Wang, YM; Abdullah, S; Luebbering, N; Langenberg, L; Duell, A; Lake, K; Lane, A; Hils, B; Vazquez Silva, O; Trapp, M; Haslam, DB; Faubion, WA; Davies, SM; Khandelwal, P. Intestinal permeability in patients undergoing stem cell transplantation correlates with systemic acute phase responses and dysbiosis. Blood advances. 2023; 7(17):5137-5151.

Smith, J; Liu, C; Beck, A; Fei, L; Brokamp, C; Meryum, S; Whaley, KG; Minar, P; Hellmann, J; Denson, LA; Margolis, P; Dhaliwal, J. Racial Disparities in Pediatric Inflammatory Bowel Disease Care: Differences in Outcomes and Health Service Utilization Between Black and White Children. Journal of Pediatrics. 2023; 260:113522.

Raygoza Garay, JA; Turpin, W; Lee, S-H; Smith, MI; Goethel, A; Griffiths, AM; Moayyedi, P; Espin-Garcia, O; Abreu, M; Aumais, GL; Yerushalmi, B; Paterson, AD; Xu, W; Croitoru, K. Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives. Gastroenterology. 2023; 165(3):670-681.

Braun, T; Sosnovski, KE; Amir, A; Benshoshan, M; Vandussen, KL; Karns, R; Levhar, N; Abbas-Egbariya, H; Hadar, R; Efroni, G; Ferrer, J; Hyams, JS; Denson, LA; Haberman, Y. Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease. JCI Insight. 2023; 8(14).

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