Gastroenterology, Hepatology and Nutrition

Faculty Labs

The Asai Lab studies genetic liver diseases that begin during development, using patient-derived stem cell models to identify molecular pathways and develop new treatments that could stop disease progression.

The Denson Lab studies the mechanisms driving chronic inflammation, growth problems, and mucosal healing in pediatric and adult inflammatory bowel disease, with a focus on finding biomarkers and new therapies.

The Huppert Lab studies the molecular and cellular signals that control liver development, bile duct formation, and regeneration, with the goal of understanding and treating congenital and chronic liver diseases.

The Miethke Lab develops better therapies for cholestatic and inflammatory liver diseases in infants, children and young adults by studying disease mechanisms, biomarkers and novel treatments.

The Minar Lab focuses on personalized medicine for children and young adults with inflammatory bowel disease by developing biomarkers and precision dosing strategies to better monitor treatment response and improve intestinal healing.

The Moore Lab studies gut health, nutrition, immunity and host-microbe interactions to improve the diagnosis, treatment and prevention of pediatric gastrointestinal disease and undernutrition.

The Takebe Lab develops complex human organoid models to study organ formation and advance new therapies, especially for pediatric intractable diseases and congenital liver disorders.

The VanDussen Lab studies how intestinal epithelial cells regulate gut health and Crohn’s disease, focusing on how disrupted communication with the immune system, diet and the microbiome drives inflammation.

The Wang Lab develops computational and mathematical tools to analyze spatial omics and imaging data, with the goal of understanding cell communication and tissue organization in inflammatory and autoimmune diseases, especially pediatric GI and liver disorders.

The Yin Lab studies the mechanisms of liver development, homeostasis and inherited chronic intrahepatic cholestasis, using animal models and genetic tools to understand known mutations, discover new disease genes and develop targeted therapies.