Publications

Sharma, A; Kudira, R; Wang, J; Miethke, A; Gandhi, CR. Differential recruitment of monocyte-derived macrophages in control and stellate cell-depleted mice during recurrent carbon tetrachloride-induced acute liver injury. Journal of Cellular Physiology. 2022.

Bass, LM; Ye, W; Hawthorne, K; Leung, DH; Murray, KF; Romero, R; Karpen, S; Rosenthal, P; Loomes, KM; Wang, KS; et al. Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia. Hepatology. 2022; 76:712-726.

Loomes, KM; Squires, RH; Kelly, D; Rajwal, S; Soufi, N; Lachaux, A; Jankowska, I; Mack, C; Setchell, KD R; Karthikeyan, P; et al. Maralixibat for the treatment of PFIC: Long-term, IBAT inhibition in an open-label, Phase 2 study. Hepatology Communications. 2022; 6:2379-2390.

Shneider, BL; Spino, CA; Kamath, BM; Magee, JC; Ignacio, RV; Huang, S; Horslen, SP; Molleston, JP; Miethke, AG; Kohli, R; et al. Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome. Hepatology Communications. 2022; 6:1922-1933.

Baker, EK; Ulm, EA; Belonis, A; Brightman, DS; Hallinan, BE; Leslie, ND; Miethke, AG; Vawter-Lee, M; Wu, Y; Pena, LD M. Clinically available testing options resulting in diagnosis in post-exome clinic at one medical center. Frontiers in Genetics. 2022; 13.

McCrary, J; Trout, AT; Mahalingam, N; Singh, R; Rojas, CC; Miethke, AG; Dillman, JR. Associations Between Quantitative MRI Metrics and Clinical Risk Scores in Children and Young Adults With Autoimmune Liver Disease. American Journal of Roentgenology. 2022; 219:142-150.

Bondoc, A; Barker, M; Mullapudi, B; Miethke, A; Tiao, G. Pediatric Living Donor Liver Transplantation Outcomes-Is it Time for Outcome Optimization of Technical Aspects of Transplantation Using Learning Networks?. Liver Transplantation and Surgery. 2022; 28:928-930.

Kaj-Carbaidwala, B; Bernieh, A; Russi, AE; Miethke, AG; Abu-El-Haija, M; Trout, AT; Gupta, A; Ricci, KW; Nathan, JD. Total pancreatectomy with islet autotransplantation in a child with pancreatic kaposiform hemangioendothelioma. Journal of Pediatric Surgery Case Reports. 2022; 81.

Li, CZ; Ogawa, H; Ng, SS; Chen, X; Kishimoto, E; Sakabe, K; Fukami, A; Hu, YC; Mayhew, CN; Hellmann, J; et al. Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency. 2022; 4.

Amevor, AA; Yodoshi, T; Trout, AT; Dillman, J; Singh, R; Jarvis, R; Fei, L; Liu, C; Taylor, A; Miethke, A; et al. Sarcopenia is highly prevalent in children with autoimmune liver diseases and is linked to visceral fat and parent-perceived general health. Liver International. 2022; 42:394-401.

Mahalingam, N; Trout, AT; Gandhi, DB; Sahay, RD; Singh, R; Miethke, AG; Dillman, JR. Associations between MRI T1 mapping, liver stiffness, quantitative MRCP, and laboratory biomarkers in children and young adults with autoimmune liver disease. Abdominal Radiology. 2022; 47:672-683.

Kudira, R; Sharma, BK; Mullen, M; Mohanty, SK; Donnelly, B; Tiao, GM; Miethke, A. Isolation and Culturing Primary Chaolangiocytes from Mouse Liver. Bio-protocol. 2021; 11.

Schultz, K; Divanovic, A; Towe, C; Miethke, A; Wusik, K; Hammill, A; Brunner, H. Clinicopathologic Conference: A Four-Year-Old Child With Digital Clubbing. Arthritis Care and Research. 2021; 73:1379-1386.

Gandhi, DB; Pednekar, A; Braimah, AB; Dudley, J; Tkach, JA; Trout, AT; Miethke, AG; Franck, MD; Heilman, JA; Dzyubak, B; et al. Assessment of agreement between manual and automated processing of liver MR elastography for shear stiffness estimation in children and young adults with autoimmune liver disease. Abdominal Radiology. 2021; 46:3927-3934.

Pham, DH; Kudira, R; Xu, L; Valencia, CA; Ellis, JL; Shi, T; Evason, KJ; Osuji, I; Matuschek, N; Pfuhler, L; et al. Deleterious Variants in ABCC12 are Detected in Idiopathic Chronic Cholestasis and Cause Intrahepatic Bile Duct Loss in Model Organisms. Gastroenterology. 2021; 161:287-300.e16.

El-Matary, W; Guthery, SL; Amir, AZ; DiGuglielmo, M; Draijer, LG; Furuya, KN; Gupta, N; Hochberg, JT; Horslen, S; Kerkar, N; et al. Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. Clinical Gastroenterology and Hepatology. 2021; 19:1067-1070.e2.

Deneau, MR; Mack, C; Mogul, D; Perito, ER; Valentino, PL; Amir, AZ; DiGuglielmo, M; Draijer, LG; El-Matary, W; Furuya, KN; et al. Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis. Hepatology. 2021; 73:1061-1073.

Deneau, MR; Mack, C; Perito, ER; Ricciuto, A; Valentino, PL; Amin, M; Amir, AZ; Aumar, M; Auth, M; Broderick, A; et al. The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children. Hepatology. 2021; 73:1074-1087.

Leonis, MA; Miethke, AG; Fei, L; Maynor, S; Chapin, CA; Bleesing, JJ H; Alonso, EM; Squires, RH. Four Biomarkers Linked to Activation of Cluster of Differentiation 8-Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure. Hepatology. 2021; 73:233-246.

Abu Ata, N; Dillman, JR; Gandhi, DB; Dudley, JA; Trout, AT; Miethke, AG. Association between liver diffusion-weighted imaging apparent diffusion coefficient values and other measures of liver disease in pediatric autoimmune liver disease patients. Abdominal Radiology. 2021; 46:197-204.

Teckman, J; Rosenthal, P; Hawthorne, K; Spino, C; Bass, LM; Murray, KF; Kerkar, N; Magee, JC; Karpen, S; Heubi, JE; et al. Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension. Journal of Pediatrics. 2020; 227:81-86.e4.

Sharma, A; Verma, AK; Kofron, M; Kudira, R; Miethke, A; Wu, T; Wang, J; Gandhi, CR. Lipopolysaccharide Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against Decapentaplegic, and CCAAT/Enhancer-Binding Protein C/EBP Transcription Factors. Hepatology. 2020; 72:1800-1818.

Dillman, JR; Tkach, JA; Gandhi, D; Singh, R; Miethke, AG; Jayaswal, A; Trout, AT. Relationship between magnetic resonance imaging spleen T1 relaxation and other radiologic and clinical biomarkers of liver fibrosis in children and young adults with autoimmune liver disease. Abdominal Radiology. 2020; 45:3709-3715.

Lam, S; Singh, R; Dillman, JR; Trout, AT; Serai, SD; Sharma, D; Sheridan, R; Su, W; Fei, L; Karns, R; et al. Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease. Hepatology Communications. 2020; 4:1680-1693.

Kassam, A; Goddard, GR; Johnston, ME; Cortez, AR; Trout, AT; Jenkins, TM; Miethke, AG; Campbell, KM; Bezerra, JA; Balistreri, WF; et al. Natural Course of Pediatric Portal Hypertension. Hepatology Communications. 2020; 4:1346-1352.

Kamath, BM; Spino, C; McLain, R; Magee, JC; Fredericks, EM; Setchell, KD; Miethke, A; Molleston, JP; Mack, CL; Squires, RH; et al. Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome. Hepatology Communications. 2020; 4:1012-1018.

Dillman, JR; Serai, SD; Miethke, AG; Singh, R; Tkach, JA; Trout, AT. Comparison of liver T1 relaxation times without and with iron correction in pediatric autoimmune liver disease. Pediatric Radiology. 2020; 50:935-942.

Pangonis, S; Paulsen, G; Andersen, H; Flores, F; Miethke, A; Peters, A; Kocoshis, S; Lazear, D; Garr, B; Schecter, M; et al. Evaluation of a change in cytomegalovirus prevention strategy following pediatric solid organ transplantation. Transplant Infectious Disease. 2020; 22.

Elisofon, SA; Magee, JC; Ng, VL; Horslen, SP; Fioravanti, V; Economides, J; Erinjeri, J; Anand, R; Mazariegos, GV; Dunn, S; et al. Society of pediatric liver transplantation: Current registry status 2011-2018. Pediatric Transplantation. 2020; 24.

Gilligan, LA; Trout, AT; Lam, S; Singh, R; Tkach, JA; Serai, SD; Miethke, AG; Dillman, JR. Differentiating pediatric autoimmune liver diseases by quantitative magnetic resonance cholangiopancreatography. Abdominal Radiology. 2020; 45:168-176.

Russell, BE; Whaley, KG; Bove, KE; Labilloy, A; Lombardo, RC; Hopkin, RJ; Leslie, ND; Prada, C; Assouline, Z; Barcia, G; et al. Expanding and Underscoring the Hepato-Encephalopathic Phenotype of QIL1/MIC13. Hepatology. 2019; 70:1066-1070.

Deneau, M; Perito, E; Ricciuto, A; Gupta, N; Kamath, BM; Palle, S; Vitola, B; Smolka, V; Ferrari, F; Amir, AZ; et al. Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course. Journal of Pediatrics. 2019; 209:92-96.e1.

Kudira, R; Silva-Lages, C; Taylor, A; Shi, T; Karns, R; Mulen, M; Zhang, W; Setchell, K; Miethke, A. SAT-376-Bile acids induce STAT3 and repress FOXP3 expression in hepatic CD4 lymphocytes under cholestatic conditions. Journal of Hepatology. 2019; 70:e799-e800.

Dillman, JR; Serai, SD; Trout, AT; Singh, R; Tkach, JA; Taylor, AE; Blaxall, BC; Fei, L; Miethke, AG. Diagnostic performance of quantitative magnetic resonance imaging biomarkers for predicting portal hypertension in children and young adults with autoimmune liver disease. Pediatric Radiology. 2019; 49:332-341.

Taylor, AE; Carey, AN; Kudira, R; Lages, CS; Shi, T; Lam, S; Karns, R; Simmons, J; Shanmukhappa, K; Almanan, M; et al. Interleukin 2 Promotes Hepatic Regulatory T Cell Responses and Protects From Biliary Fibrosis in Murine Sclerosing Cholangitis. Hepatology. 2018; 68:1905-1921.

Shneider, BL; Spino, C; Kamath, BM; Magee, JC; Bass, LM; Setchell, KD; Miethke, A; Molleston, JP; Mack, CL; Squires, RH; et al. Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome. Hepatology Communications. 2018; 2:1184-1198.

Serai, SD; Trout, AT; Miethke, A; Diaz, E; Xanthakos, SA; Dillman, JR. Putting it all together: established and emerging MRI techniques for detecting and measuring liver fibrosis. Pediatric Radiology. 2018; 48:1256-1272.

Ng, VL; Sorensen, LG; Alonso, EM; Fredericks, EM; Ye, W; Moore, J; Karpen, SJ; Shneider, BL; Molleston, JP; Bezerra, JA; et al. Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study. Journal of Pediatrics. 2018; 196:139-147.e3.