Publications

Abu Ata, N; Dillman, JR; Gandhi, DB; Dudley, JA; Trout, AT; Miethke, AG. Association between liver diffusion-weighted imaging apparent diffusion coefficient values and other measures of liver disease in pediatric autoimmune liver disease patients. Abdominal Radiology. 2021; 46:197-204.

Annabi, N; Baker, M; Boettiger, A; Chakraborty, D; Chen, Y; Corbett, KS; Correia, B; Dahlman, J; de Oliveira, T; Ertuerk, A; et al. Voices of biotech research. Nature Biotechnology. 2021; 39:281-286.

Attia, SL; Softic, S; Mouzaki, M. Evolving Role for Pharmacotherapy in NAFLD/NASH. Clinical and Translational Science. 2021; 14:11-19.

Barrow, F; Khan, S; Fredrickson, G; Wang, H; Dietsche, K; Parthiban, P; Robert, S; Kaiser, T; Winer, S; Herman, A; et al. Microbiota-Driven Activation of Intrahepatic B Cells Aggravates Nonalcoholic Steatohepatitis through Innate and Adaptive Signaling. Hepatology. 2021.

Bell, M; Cole, CR; Hansen, NI; Duncan, AF; Hintz, SR; Adams-Chapman, I. Neurodevelopmental and Growth Outcomes of Extremely Preterm Infants with Short Bowel Syndrome. Journal of Pediatrics. 2021; 230:76-83.e5.

Bezerra, JA; Asai, A; Tiao, G; Mullapudi, B; Balistreri, WF. Biliary Atresia and Other Disorders of the Extrahepatic Bile Ducts. Liver Disease in Children. 2021.

Braun, JM; Eliot, M; Papandonatos, GD; Buckley, JP; Cecil, KM; Kalkwarf, HJ; Chen, A; Eaton, CB; Kelsey, K; Lanphear, BP; et al. Gestational perfluoroalkyl substance exposure and body mass index trajectories over the first 12 years of life. International Journal of Obesity. 2021; 45:25-35.

Clarkston, K; Lee, J; Donoghue, S; Peters, H; Eiroa, H; Shah, AA; Loomes, K; Wen, J; Oliver, M; Hardikar, W; et al. Acute liver dysfunction with delayed peak of serum aminotransferase levels as a presentation of ornithine transcarbamylase deficiency in females. American Journal of Medical Genetics, Part A. 2021; 185:909-915.

Clarkston, K; Oliveira, SB. 50 Years Ago in TheJournalofPediatrics: Food for Thought: Parenteral Nutrition. Journal of Pediatrics. 2021; 228.

Colman, RJ; Dhaliwal, J; Rosen, MJ. Predicting Therapeutic Response in Pediatric Ulcerative Colitis-A Journey Towards Precision Medicine. Frontiers in Pediatrics. 2021; 9.

Colman, RJ; Portocarrero-Castillo, A; Chona, D; Hellmann, J; Minar, P; Rosen, MJ. Favorable Outcomes and Anti-TNF Durability After Addition of an Immunomodulator for Anti-Drug Antibodies in Pediatric IBD Patients. Inflammatory Bowel Diseases. 2021; 27:507-515.

Cunningham, NR; Kalomiris, A; Peugh, J; Farrell, M; Pentiuk, S; Mallon, D; Le, C; Moorman, E; Fussner, L; Dutta, RA; et al. Cognitive Behavior Therapy Tailored to Anxiety Symptoms Improves Pediatric Functional Abdominal Pain Outcomes: A Randomized Clinical Trial. Journal of Pediatrics. 2021; 230:62-70.e3.

Deneau, MR; Mack, C; Mogul, D; Perito, ER; Valentino, PL; Amir, AZ; DiGuglielmo, M; Draijer, LG; El-Matary, W; Furuya, KN; et al. Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis. Hepatology. 2021; 73:1061-1073.

Deneau, MR; Mack, C; Perito, ER; Ricciuto, A; Valentino, PL; Amin, M; Amir, AZ; Aumar, M; Auth, M; Broderick, A; et al. The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children. Hepatology. 2021; 73:1074-1087.

Dhaliwal, J; Erdman, L; Drysdale, E; Rinawi, F; Muir, J; Walters, TD; Siddiqui, I; Griffiths, AM; Church, PC. Accurate Classification of Pediatric Colonic Inflammatory Bowel Disease Subtype Using a Random Forest Machine Learning Classifier. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:262-269.

Dhaliwal, J; Tuna, M; Murthy, S; Shah, B; Griffiths, A; Benchimol, EI. A166 INCIDENCE OF INFLAMMATORY BOWEL DISEASE IN SOUTH ASIAN AND CHINESE PEOPLE: A POPULATION-BASED COHORT STUDY FROM ONTARIO, CANADA. 2021; 4:175-177.

Dobrindt, K; Hoagland, DA; Seah, C; Kassim, B; O'Shea, CP; Murphy, A; Iskhakova, M; Fernando, MB; Powell, SK; Deans, PJ M; et al. Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection. Stem Cell Reports. 2021; 16:505-518.

Francis, M; Balwani, M; Balistreri, W; D’Antiga, L; Fang, S; Jones, S; Ros, E; Abel, F; Wilson, D. A216 CLINICAL MANIFESTATIONS OF LYSOSOMAL ACID LIPASE DEFICIENCY (LAL-D): THE INTERNATIONAL LAL-D REGISTRY. 2021; 4:248-249.

Freeman, AJ; Maqbool, A; Bellin, MD; Goldschneider, KR; Grover, AS; Hartzell, C; Piester, TL; Szabo, F; Kiernan, BD; Khalaf, R; et al. Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:324-340.

Funata, M; Nio, Y; Erion, DM; Thompson, WL; Takebe, T. The promise of human organoids in the digestive system. Cell Death and Differentiation. 2021; 28:84-94.

Galloway, DP; Mathis, MS; Wilkinson, LT; Venick, RS; Wendel, D; Cole, CR; Martin, CA. Effect of the COVID-19 Pandemic on Pediatric Intestinal Failure Healthcare Delivery. Journal of Parenteral and Enteral Nutrition. 2021; 45:50-56.

Ghany, MG; Lok, AS F; Dienstag, JL; Feinstone, SM; Hoofnagle, JH; Liang, TJ; Seeff, LB; Cohen, DE; Bezerra, JA; Chung, RT. The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence. Hepatology. 2021.

Grasberger, H; Magis, AT; Sheng, E; Conomos, MP; Zhang, M; Garzotto, LS; Hou, G; Bishu, S; Nagao-Kitamoto, H; El-Zataari, M; et al. DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk. Journal of Clinical Investigation. 2021.

Gray, WN; Wagoner, ST; Schaefer, MR; Reed, B; Morgan, P; Holbrook, E; Yacyshyn, B; MacKner, L; Young, M; Maddux, M; et al. Transition to Adult IBD Care: A Pilot Multi-Site, Telehealth Hybrid Intervention. Journal of Pediatric Psychology. 2021; 46:1-11.

Gupta, S; Mukkada, V; Dellon, E; Gold, B; Collins, M; Katzka, D; Falk, G; Lan, L; Desai, N; Williams, J; et al. Efficacy And Safety Of Budesonide Oral Suspension In A Pediatric Population: Pooled Data From A Phase 2 And Phase 3 Trial In Patients With Eosinophilic Esophagitis. Journal of Allergy and Clinical Immunology. 2021; 147.

Haberman, Y; Iqbal, NT; Ghandikota, S; Mallawaarachchi, I; Tzipi Braun, ; Dexheimer, PJ; Rahman, N; Hadar, R; Sadiq, K; Ahmad, Z; et al. Mucosal Genomics Implicate Lymphocyte Activation and Lipid Metabolism in Refractory Environmental Enteric Dysfunction. Gastroenterology. 2021.

Haberman, Y; Minar, P; Karns, R; Dexheimer, PJ; Ghandikota, S; Tegge, S; Shapiro, D; Shuler, B; Venkateswaran, S; Braun, T; et al. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. Journal of Crohn's and Colitis. 2021.

Hayashi, H; Osaka, S; Sakabe, K; Fukami, A; Kishimoto, E; Aihara, E; Sabu, Y; Mizutani, A; Kusuhara, H; Naritaka, N; et al. Modeling Human Bile Acid Transport and Synthesis in Stem Cell-Derived Hepatocytes with a Patient-Specific Mutation. Stem Cell Reports. 2021; 16:309-323.

Hellmann, J; Ta, A; Haslam, D; Lake, K; Bezold, R; Jackson, K; Bonkowski, E; Andersen, H; Dirksing, K; Ollberding, N; et al. MICROBIAL SHIFTS ARE ASSOCIATED WITH PATIENT-REPORTED SYMPTOMS IRRESPECTIVE OF MUCOSAL INFLAMMATION IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE. Gastroenterology. 2021; 160:s55-s56.

Hellmann, J; Ta, A; Haslam, D; Lake, K; Bezold, R; Jackson, K; Bonkowski, E; Andersen, H; Dirksing, K; Ollberding, N; et al. MICROBIAL SHIFTS ARE ASSOCIATED WITH PATIENT-REPORTED SYMPTOMS IRRESPECTIVE OF MUCOSAL INFLAMMATION IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE. Inflammatory Bowel Diseases. 2021; 27:s40-s41.

Hill, S; Carter, BA; Cohran, V; Horslen, S; Kaufman, SS; Kocoshis, SA; Mercer, DF; Merritt, RJ; Pakarinen, MP; Protheroe, S; et al. Safety Findings in Pediatric Patients During Long-Term Treatment With Teduglutide for Short-Bowel Syndrome-Associated Intestinal Failure: Pooled Analysis of 4 Clinical Studies. Journal of Parenteral and Enteral Nutrition. 2021.

Hsu, EK; Ambartsumyan, L; Wahbeh, GT; Zerr, DM; Lin, TK. Pediatric Endoscopy During the COVID-19 Pandemic: Addressing the Implications of Universal Preprocedural Testing for PPE Utilization. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:e25-e26.

Hyman, PE; Santucci, NR. 7 Approach to the Child with a Functional Gastrointestinal Disorder. Pediatric Gastrointestinal and Liver Disease. 2021.

Kassam, AF; Cortez, AR; Johnston, ME; Zang, H; Fei, L; Lin, TK; Abu-El-Haija, M; Nathan, JD. Total pancreatectomy with islet autotransplantation reduces resource utilization in pediatric patients. American Journal of Surgery. 2021.

Khlevner, J; Rosen, R; Ambartsumyan, L; Lusman, SS; Rosen, JM; Yacob, D; Mousa, H; Nurko, S; Di Lorenzo, C; Boruta, M; et al. Development of Entrustable Professional Activities and Standards in Training in Pediatric Neurogastroenterology and Motility: North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and American Neurogastroenterology and Motility Society Position Paper. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:168-180.

Kocoshis, SA. Even When the Wound Is Healed, the Scar Remains . Journal of Pediatrics. 2021; 230:11-12.

Kohli, R; Bove, KE; Xanthakos, SA. Non-Alcoholic Fatty Liver Disease in Children. Liver Disease in Children. 2021.

Koike, H; Iwasawa, K; Ouchi, R; Maezawa, M; Kimura, M; Kodaka, A; Nishii, S; Thompson, WL; Takebe, T. Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells. Nature Protocols. 2021; 16:919-936.

Kottyan, LC; Trimarchi, MP; Lu, X; Caldwell, JM; Maddox, A; Parameswaran, S; Lape, M; D'Mello, RJ; Bonfield, M; Ballaban, A; et al. Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes. Journal of Allergy and Clinical Immunology. 2021; 147:255-266.

Leonis, MA; Miethke, AG; Fei, L; Maynor, S; Chapin, CA; Bleesing, JJ H; Alonso, EM; Squires, RH. Four Biomarkers Linked to Activation of Cluster of Differentiation 8-Positive Lymphocytes Predict Clinical Outcomes in Pediatric Acute Liver Failure. Hepatology. 2021; 73:233-246.

Li, N; Liu, Y; Papandonatos, GD; Calafat, AM; Eaton, CB; Kelsey, KT; Cecil, KM; Kalkwarf, HJ; Yolton, K; Lanphear, BP; et al. Gestational and childhood exposure to per- and polyfluoroalkyl substances and cardiometabolic risk at age 12 years. Environmental International. 2021; 147.

Lindquist, DM; Fugate, EM; Wang, J; Sharma, A; Gandhi, CR; Dillman, JR. MRI Measures of Murine Liver Fibrosis. Journal of Magnetic Resonance Imaging. 2021.

Lipshaw, MJ; Zamor, RL; Carson, R; Mallon, D; Sobolewski, B; Vukovic, AA; Kurowski, EM. Evidence-based Standardization of Constipation Management in the Emergency Department: A Quality Improvement Study. Pediatric Quality and Safety. 2021; 6.

Long, SS; Welch, TR; Madan, RP; McDevitt, M; Balistreri, WF. The Nimbleness and Resource Costs of Expedited Review and Concerns of Duplicate Publication: SARS-CoV-2 Manuscripts Submitted to The Journal of Pediatrics. Journal of Pediatrics. 2021; 229:5-7.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

Lyles, JL; Mulgund, AA; Bauman, LE; Su, W; Fei, L; Chona, DL; Sharma, P; Etter, RK; Hellmann, J; Denson, LA; et al. Effect of a Practice-wide Anti-TNF Proactive Therapeutic Drug Monitoring Program on Outcomes in Pediatric Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 2021; 27:482-492.

Mai, DH; Newton, H; Farrell, PR; Mullan, P; Kapoor, R. Assessment of Clinical Leadership Training Needs in Senior Pediatric Residents. Journal of Medical Education and Curricular Development. 2021; 8.

Malik, A; Thanekar, U; Amarachintha, S; Mourya, R; Nalluri, S; Bondoc, A; Shivakumar, P. "Complimenting the Complement ": Mechanistic Insights and Opportunities for Therapeutics in Hepatocellular Carcinoma. Frontiers in Oncology. 2021; 10.

Mohanty, SK; Donnelly, B; Temple, H; Ortiz-Perez, A; Mowery, S; Lobeck, I; Dupree, P; Poling, HM; McNeal, M; Mourya, R; et al. HMGB1 release by cholangiocytes governs biliary atresia pathogenesis and correlates with increases in afflicted infants. Hepatology. 2021.

Okura, H; Yodoshi, T; Thapaliya, S; Trout, AT; Mouzaki, M. Underreporting of Hepatic Steatosis in Children: A Missed Opportunity for Early Detection. Journal of Pediatrics. 2021.

Oliveira, SB. Why Is Avoidant-Restrictive Food Intake Disorder Relevant to the Pediatric Gastroenterologist?. JAMA Pediatrics. 2021.

Oliveira, SB. Helicobacter Pylori infection within a colonic interposition. Journal of Pediatric Surgery Case Reports. 2021; 65.

Orkin, S; Yodoshi, T; Sun, Q; Fei, L; Meryum, S; Arce-Clachar, AC; Bramlage, K; Beck, AF; Mouzaki, M. Can Baseline Characteristics be Used to Predict Liver Disease Outcomes in Pediatric Nonalcoholic Fatty Liver Disease?. Obesity Research. 2021; 29:171-176.

Pandurangi, S; El-Chammas, K; Kocoshis, SA; Kaul, A. Phenotypic diversity in clinical and manometric characteristics of pediatric patients with ACTG2 mutations. Journal of Pediatric Surgery Case Reports. 2021; 66.

Parsons, K; Guarnieri, K; Tadesse, D; Hossain, MM; Mukkada, V; Rothenberg, M; Guilbert, T; Durrani, S. Active Eosinophilic Esophagitis is Associated with Increased Asthma Severity and Lower Lung Function in Children with Comorbid Asthma. Journal of Allergy and Clinical Immunology. 2021; 147.

Patel, N; Sellers, ZM; Grover, A; Liu, QY; Maqbool, A; Morinville, VD; Abu-El-Haija, M; Husain, SZ. Endoscopic Pancreatic Function Testing (ePFT) in Children: A Position Paper From the NASPGHAN Pancreas Committee. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:144-150.

Pham, D; Kudira, R; Xu, L; Valencia, CA; Ellis, JL; Shi, T; Evason, KJ; Osuji, I; Matuschek, N; Pfuher, L; et al. Deleterious variants in ABCC12 are detected in idiopathic chronic cholestasis and cause intrahepatic bile duct loss in model organisms: ABCC12 pathogenic variants lead to cholestasis. Gastroenterology. 2021.

Porta, G; de Carvalho, E; Santos, JL; Gama, J; Bezerra, JA; Borges, CV; Seixas, RB P M; Ferreira, A; Miura, IK; Silveira, TR; et al. Autoimmune Hepatitis: Predictors of Native Liver Survival in Children and Adolescents. Journal of Pediatrics. 2021; 229:95-101.e3.

Potdar, AA; Dube, S; Naito, T; Li, K; Botwin, G; Haritunians, T; Li, D; Casero, D; Yang, S; Bilsborough, J; et al. Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease. Gastroenterology. 2021; 160:809-822.e7.

Rogers, ME; Balistreri, WF. Cascade of care for children and adolescents with chronic hepatitis C. World Journal of Gastroenterology. 2021; 27:1117-1131.

Saad, M; Rellinger, E; Garrison, A; Oliveira, S; Johnson, N; Putnam, P. Jejunopericardiac Fistula in a Patient With Colonic Interposition and a Gastrojejunostomy Tube. Journal of Pediatric Gastroenterology and Nutrition. 2021.

Santucci, NR; Chogle, A; Mascarenhas, M; Leiby, A; Borlack, RE; Lee, A; Perez, M; Russell, A; Yeh, AM. Non-pharmacologic Approach to Pediatric Constipation. Complementary Therapies in Medicine. 2021.

Shinozawa, T; Kimura, M; Cai, Y; Saiki, N; Yoneyama, Y; Ouchi, R; Koike, H; Maezawa, M; Zhang, RR; Dunn, A; et al. High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids. Gastroenterology. 2021; 160:831-846.e10.

Somineni, HK; Nagpal, S; Venkateswaran, S; Cutler, DJ; Okou, DT; Haritunians, T; Simpson, CL; Begum, F; Datta, LW; Quiros, AJ; et al. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American Journal of Human Genetics. 2021; 108:431-445.

Summer, SS; Wong, BL; Rutter, MM; Horn, PS; Tian, C; Rybalsky, I; Shellenbarger, KC; Kalkwarf, HJ. Age-related changes in appendicular lean mass in males with Duchenne muscular dystrophy: A retrospective review. Muscle and Nerve. 2021; 63:231-238.

Surbek, M; Tse, W; Moriggl, R; Han, X. A centric view of JAK/STAT5 in intestinal homeostasis, infection, and inflammation. Cytokine. 2021; 139.

Ta, AD; Ollberding, NJ; Karns, R; Haberman, Y; Alazraki, AL; Hercules, D; Baldassano, R; Markowitz, J; Heyman, MB; Kim, S; et al. Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease. Inflammatory Bowel Diseases. 2021.

Thompson, WL; Takebe, T. Human liver model systems in a dish. Development Growth and Differentiation. 2021; 63:47-58.

Trout, AT; Anupindi, SA; Freeman, AJ; Macias-Flores, JA; Martinez, JA; Parashette, KR; Shah, U; Squires, JH; Morinville, VD; Husain, SZ; et al. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology Joint Position Paper on Noninvasive Imaging of Pediatric Pancreatitis: Literature Summary and Recommendations. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:151-167.

Trout, AT; Anupindi, SA; Husain, SZ; Morinville, VD; Abu-El-Haija, M. Noninvasive imaging of pediatric pancreatitis: joint recommendations from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition and the Society for Pediatric Radiology. Pediatric Radiology. 2021; 51:8-10.

Trout, AT; Ayyala, RS; Murati, MA; Squires, JH; Callahan, MJ; Chavhan, GB; Abu-El-Haija, M; Anupindi, SA. Current State of Imaging of Pediatric Pancreatitis: AJR Expert Panel Narrative Review. American Journal of Roentgenology. 2021.

Trout, AT; Nolan, HR; Abu-El-Haija, M; Fei, L; Lin, TK; Elder, DA; Nathan, JD. Imaging prediction of islet yield and post-operative insulin requirement in children undergoing total pancreatectomy with islet autotransplantation. Pancreatology. 2021; 21:269-274.

Ungaro, RC; Hu, L; Ji, J; Nayar, S; Kugathasan, S; Denson, LA; Hyams, J; Dubinsky, MC; Sands, BE; Cho, JH. Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease. Alimentary Pharmacology and Therapeutics. 2021; 53:281-290.

Vitale, DS; Lin, TK. Trends in Pediatric Endoscopic Retrograde Cholangiopancreatography and Interventional Endoscopy. Journal of Pediatrics. 2021.

Wendel, D; Mezoff, EA; Raghu, VK; Kinberg, S; Soden, J; Avitzur, Y; Rudolph, JA; Gniadek, M; Cohran, VC; Venick, RS; et al. Management of Central Venous Access in Children With Intestinal Failure: A Position Paper From the NASPGHAN Intestinal Rehabilitation Special Interest Group. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:474-486.

Xanthakos, SA. Pharmacological, Endoscopic, Metabolic, and Surgical Procedures for Nonalcoholic Fatty Liver Disease. Clinical Liver Disease. 2021; 17:209-214.

Xiong, Y; Mizuno, T; Colman, R; Hyams, J; Noe, JD; Boyle, B; Tsai, YT; Dong, M; Jackson, K; Punt, N; et al. Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease. Clinical Pharmacology and Therapeutics. 2021.

Yodoshi, T; Orkin, S; Arce-Clachar, AC; Bramlage, K; Xanthakos, SA; Mouzaki, M; Valentino, PL. Significance of autoantibody seropositivity in children with obesity and non-alcoholic fatty liver disease. Pediatric obesity. 2021; 16.