Takebe Lab

Shinozawa T, Yoshikawa H-Y, Takebe T*; Reverse Engineering Organ Buds through Self-Driven Condensation and Organization. Developmental Biology 2016 Jun 27. pii: S0012-1606(16)30156-7. (*Correspondence)

Takahashi Y, Takebe T*, Taniguchi H*: Engineering pancreatic tissues from stem cells towards therapy. Regenerative Therapy 2016(3): 15-23, 1 Mar 2016, doi: 10.1016/j.reth.2016.01.002 (*Joint corresponding authors)

Kagimoto S, Takebe T*, Kobayashi S, Yabuki Y, Hori A, Hirotomi K, Mikami T, Uemura T, Maegawa J, Taniguchi H: Autotransplantation of monkey ear perichondrium-derived progenitor cells for cartilage reconstruction. Cell transplantation. (*Joint corresponding authors), 2016;25(5):951-62.

Takebe T*, Enomura M, Yoshizawa E, Kimura M, Koike H, Ueno Y, Matsuzaki T, Yamazaki T, Toyohara T, Osafune K, Nakauchi H, Yoshikawa H-Y, Taniguchi H: Vascularized And Complex Organ Buds From Diverse Tissues Via Mesenchymal Cell-Driven Condensation. Cell Stem Cell, (*Corresponding author),16(5): 556-565, 2015 

• Selected as Cover Work 
• Selected as Best of Cell Stem Cell 
• Previewed in Cell Stem Cell
• Featured in Nature Method

Rashid, T., Takebe, T., and Nakauchi, H. Novel strategies for liver therapy using stem cells. Gut 64, 1-4, 2015.

Zhang, R.R., Koike, H., and Takebe, T. (2015). The visualization of human organogenesis from stem cells by recapitulating multicellular interactions. In Hyper Bio Assembler for 3D Cellular Systems, pp. 275-283, 2015

Lee S, Takahashi Y, Lee KM, Mizuno M, Nemono JG, Takebe T, Lee JI: Viability and functional assessment of murine pancreatic islets after transportation between Korea and Japan. Transplant Proc. 2015 Apr; 47(3):738-41.

Takebe T *, Kobayashi S, Suzuki H, Mizuno M, Chang YM, Yoshizawa E, Kimura M, Hori A, Asano J, Maegawa J, Taniguchi H: Transient vascularization of transplanted human adult–derived progenitors promotes self-organizing cartilage. Journal of Clinical Investigation, 2014 Oct 1;124(10):4325-34. (*:  Corresponding author)

Takebe T*, Miyazaki L, Takayama M, Koike H, Kimura M, Enomura M, Zheng YW, Sekine K, Taniguchi H: Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture. Methods Mol Biol. 2014;1210:131-41. doi: 10.1007/978-1-4939-1435-710. (*:  Corresponding author)

Takebe T*, Zhang RR, Koike H, Kimura M, Yoshizawa E, Enomura M, Sekine K, Taniguchi H*: Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature Protocols 9, 396–409 (2014). (*:  Corresponding author)

Koike H, Ueno Y, Naito T, Shiina T, Ouchi R, Obana Y, Mori M, Sekine K, Takebe T, Zheng YW, Isono K, Koseki H, Taniguchi H: Ring1B Promotes Hepatic Stem/Progenitor Cell Expansion via Simultaneous Suppression of Cdkn1a and Cdkn2a. Hepatology, 2014 Jul;60(1):323-33.

Koike N*, Sekine K, Fujiwara R, Amiya T, Zheng YW, Taniguchi H*: Engineering of human hepatic tissue with functional vascular networks. Organogenesis, 10 (2), 0-1. (*: Corresponding author) 

Takebe T*, Sekine K, Enomura M, Koike H, Zhang RR, Ueno Y, Zheng YW, Koike N, Aoyama S, Adachi Y, Taniguch H*: Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature, 499, 481–484, 2013. (*:  Corresponding author) 

• Selected as Science Breakthrough of the Year
• Selected as Word Top5 discovery, Discover Magazine
• Featured in Nature, Nature Medicine, Cell Stem Cell, Gastroenterology, Hepatology, Cell Research
• Featured in The Economist, New Scientist magazine, Newton, etc

Zhang RR^1＊, Takebe T^1＊, Miyazaki L, Takayama M, Koike H, Kimura M, Enomura M, Zheng YW, Sekine K, Taniguchi H: Efficient Hepatic Differentiation of Human Induced Pluripotent Stem Cells In A Three-Dimensional Microscale Culture. Stem Cells and Tissue Repair. (1: Equal contribution, *:  Corresponding author) 

Mizuno M, Kobayashi S, Takebe T, Kan H, Yabuki Y, Matsuzaki T, Yoshikawa HY, Nakabayashi S, JeongIk L, Maegawa J, Taniguchi H: Reconstruction of joint hyaline cartilage by autologous progenitor cells derived from ear elastic cartilage. Stem Cells, 32(3): 816-21