The VanDussen lab is located at the Cincinnati Children’s Hospital Medical Center in the Department of Pediatrics and Division of Gastroenterology, Hepatology, & Nutrition. We explore how the intestinal epithelium contributes to human health and disease. Our lab focuses on Crohn’s disease, a chronic inflammatory condition of the gastrointestinal tract that currently has no cure. Epithelial cells are situated physically at the interface between the body’s immune cells and external environmental factors, such as diet and the microbiome. Loss of balanced communication between these compartments drives unchecked inflammation in Crohn’s disease.