Ambrose, EE; Latham, TS; Songoro, P; Charles, M; Lane, AC; Stuber, SE; Makubi, AN; Ware, RE; Smart, LR. Hydroxyurea with dose escalation for primary stroke risk reduction in children with sickle cell anaemia in Tanzania (SPHERE): an open-label, phase 2 trial. The Lancet Haematology. 2023; 10:e261-e271.

Azucenas, CR; Stewart, M; Voulgaridou, A; Seu, K; Kalfa, TA. Inducible Knockout of Codanin-1: An Adult Mouse Model of Congenital Dyserythropoietic Anemia Type-I. Blood. 2023; 142:2450.

Betensky, M; Mosha, M; Tarango, C; Anupam, V; Bhat, R; Kucine, N; Nakano, T; Woods, G; Nakar, C; Amankwah, E; et al. OC 38.4 Transient Antiphospholipid Antibodies, Antiphospholipid Syndrome and Clinical Outcomes in Patients <21 Years Old with Provoked Venous Thromboembolism: Analysis from the Kids-DOTT Multinational Trial. Research and Practice in Thrombosis and Haemostasis. 2023; 7:100519.

Bilston, L; Uminski, K; Kalfa, TA; Husami, A; Goodyear, MD; Rydz, N. A Novel Beta Globin Frameshift Mutation Causing Autosomal Dominant Beta Thalassemia. Blood. 2023; 142:1105.

Borst, AJ; Hammill, AM; Crary, SE; McLean, TW; Felton, T; Blatt, J. Barriers to Genetic Testing in Vascular Malformations. JAMA Network Open. 2023; 6:e2314829.

Broder, MS; Adams, DM; Canaud, G; Collins, C; Davis, K; Frieden, IJ; Gibbs, SN; Hammill, AM; Keppler-Noreuil, KM; Nakano, TA; et al. RAND/UCLA Modified Delphi Panel on the Severity, Testing, and Medical Management of PIK3CA-Related Spectrum Disorders (PROS). 2023; 4:e067.

Cantrell, R; Feldman, H; Rosenfeldt, L; Ali, A; Sharma, B; Revenko, A; Monia, B; Waggoner, S; Palumbo, J. PB0727 The Role of Thrombin and Thrombin Signaling in Chronic LCMV Infection. Research and Practice in Thrombosis and Haemostasis. 2023; 7:101315.

Ceolan, J; Seu, K; Ntoumaziou, A; Elgammal, Y; Emberesh, S; Bilston, L; Richards, D; Dickerson, KE; Chonat, S; Rydz, N; et al. Erythrocyte Disorders Mimicking Congenital Dyserythropoietic Anemia Based on Bone Marrow Pathology Exposed By Genetic Evaluation. Blood. 2023; 142:2459.

Cohen, C; Powers, J; Tarango, C. Emicizumab Use in Infancy: A Survey of United States Pediatric Hemophilia Treatment Center Medical Directors. Blood. 2023; 142:1242.

Cohen-Cutler, S; Blatt, J; Bayliff, S; Iacobas, I; Hammill, A; Sisk, BA. Vascular Anomalies Care in the United States: A Cross-Sectional National Survey. The Journal of Pediatrics. 2023; 261:113579.

Coleman, KD; McKinley, K; Ellison, AM; Alpern, ER; Hariharan, S; Topoz, I; Wurtz, M; Nielsen, B; Cook, LJ; Morris, CR; et al. Return visit rates after an emergency department discharge for children with sickle cell pain episodes. Pediatric Blood and Cancer. 2023; 70:e30553.

Coleman, KD; McKinley, K; Ellison, AM; Alpern, ER; Hariharan, S; Topoz, I; Wurtz, M; Nielsen, B; Cook, LJ; Morris, CR; et al. Association between Acute Pain Scores in Children with Sickle Cell Disease and Emergency Department Disposition and Return Visit Rates. Blood. 2023; 142:3874.

Crosby, LE; Lang, A; Mara, C; Quinn, CT; Schultz, CL; Bear, B; Akintobi, TE; Miller, RE; Hildenbrand, AK. Patterns of Nonadherence to Hydroxyurea in Pediatric Sickle Cell Disease. Blood. 2023; 142:7198.

Deng, L; Costa, F; Blake, KJ; Choi, S; Chandrabalan, A; Yousuf, MS; Shiers, S; Dubreuil, D; Vega-Mendoza, D; Rolland, C; et al. S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis. Cell. 2023; 186:5375-5393.e25.

Dong, M; Ware, RE; Dallmann, A; Vinks, AA. Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: Current evidence and knowledge gaps. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2023; 43:419-429.

Earley, EJ; Kelly, S; Fang, F; Alencar, CS; Rodrigues, DD O W; Soares Cruz, DT; Flanagan, J; Ware, RE; Zhang, X; Gordeuk, V; et al. Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. British Journal of Haematology. 2023; 201:343-352.

Elgammal, Y; Risinger, M; Husami, A; Walden, J; Gupta, S; Shah, NC; Boyer, J; Abajas, YL; Winstead, M; Miller, DW; et al. Congenital Dyserythropoietic Anemia Type II: An Update from the Congenital Dyseryhtropoietic Anemia Registry of North America (CDAR). Blood. 2023; 142:1079.

Engel, ER; Hammill, A; Adams, D; Phillips, RJ; Jeng, M; Tollefson, MM; Iacobas, I; Schiff, D; Greenberger, S; Kelly, M; et al. Response to sirolimus in capillary lymphatic venous malformations and associated syndromes: Impact on symptomatology, quality of life, and radiographic response. Pediatric Blood and Cancer. 2023; 70:e30215.

Fenchel, L; Jackson, F; Walker, B; Manuel, C; Hooks, D; Allen, T; Thant, MM; Karkoska, K; Smart, LR; Joffe, NE; et al. Improving Transition of Emerging Adults with Sickle Cell Disease to Adult Care through a Multidisciplinary Process: The Development of a Transition Clinic to Support Transition Success. Blood. 2023; 142:5055.

Garland, K; Mullins, E; Bercovitz, RS; Rodriguez, V; Connors, J; Sokkary, N. Hemostatic considerations for gender affirming care. Thrombosis Research. 2023; 230:126-132.

Grover, SP; Bharathi, V; Posma, JJ; Griffin, JH; Palumbo, JS; Mackman, N; Antoniak, S. Thrombin-mediated activation of PAR1 enhances doxorubicin-induced cardiac injury in mice. Blood Advances. 2023; 7:1945-1953.

Hernández, G; Romero-Cortadellas, L; Ferrer-Cortès, X; Venturi, V; Dessy-Rodriguez, M; Olivella, M; Husami, A; de Soto, CP; Morales-Camacho, RM; Villegas, A; et al. Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III. Haematologica: the hematology journal. 2023; 108:581-587.

Hildenbrand, AK; Kidwell, KM; McGrady, ME; Quinn, CT; Crosby, LE; Mara, CA. Feasibility of Electronic Medication Monitoring Among Adolescents and Emerging Adults with Sickle Cell Disease. Patient Preference and Adherence. 2023; 17:3167-3171.

Hulbert, ML; Manwani, D; Meier, ER; Alvarez, OA; Brown, RC; Callaghan, MU; Campbell, AD; Coates, TD; Frei-Jones, MJ; Hankins, JS; et al. Consensus definition of essential, optimal, and suggested components of a pediatric sickle cell disease center. Pediatric Blood and Cancer. 2023; 70:e29961.

Josselsohn, R; Barnes, BJ; Kalfa, TA; Blanc, L. Navigating the marrow sea towards erythromyeloblastic islands under normal and inflammatory conditions. Current Opinion in Hematology. 2023; 30:80-85.

Josselsohn, R; Vagrecha, A; LaPan, M; Papoin, J; Kamen, J; Cho, YM; Rao, R; Romano, L; Salomonis, N; Kalfa, TA; et al. Irf5 Expression in Macrophages Contributes to Iron Regulation within Erythromyeloblastic Islands. Blood. 2023; 142:920.

Kahn, SR; Arnold, DM; Casari, C; Desch, KC; Devreese, KM J; Favaloro, EJ; Gaertner, F; Gouw, SC; Gresele, P; Griffioen, AW; et al. Illustrated State-of-the-Art Capsules of the ISTH 2023 Congress. Research and Practice in Thrombosis and Haemostasis. 2023; 7:100193.

Kilian, A; Latino, GA; White, AJ; Ratjen, F; McDonald, J; Whitehead, KJ; Gossage, JR; Krings, T; Lawton, MT; Kim, H; et al. Comparing Characteristics and Treatment of Brain Vascular Malformations in Children and Adults with HHT. Journal of Clinical Medicine. 2023; 12:2704.

Kim, TO; Geris, JM; Grimes, AB; Grace, RF; Lambert, MP; Rose, MJ; Shimano, KA; Niss, O; Neunert, C; Nakano, TA; et al. Genetic Variants in Canonical Wnt Signaling Pathway Associated with Pediatric ITP. Blood. 2023; 142:2593.

Littner, L; Thomas, E; Doyle, J; Hendrickson, J; Adkins, S; Mooney, L; Tarango, C. Improving bleeding disorder treatment log adherence: An application of the information-motivation-behavioral skills model. Haemophilia. 2023; 29:180-185.

Liy-Wong, C; Tarango, C; Pope, E; Coates, T; Bruckner, AL; Feinstein, JA; Schwieger-Briel, A; Hubbard, LD; Jane, C; Torres-Pradilla, M; et al. Consensus guidelines for diagnosis and management of anemia in epidermolysis bullosa. Orphanet Journal of Rare Diseases. 2023; 18:38.

Maria, NI; Papoin, J; Raparia, C; Sun, Z; Josselsohn, R; Lu, A; Katerji, H; Syeda, MM; Polsky, D; Paulson, R; et al. Human TLR8 induces inflammatory bone marrow erythromyeloblastic islands and anemia in SLE-prone mice. Life Science Alliance. 2023; 6:e202302241.

McDaniel, CG; Adams, DM; Steele, KE; Hammill, AM; Merrow, AC; Crane, JL; Smith, CL; Kozakewich, HP W; Le Cras, TD. Kaposiform lymphangiomatosis: Diagnosis, pathogenesis, and treatment. Pediatric Blood and Cancer. 2023; 70:e30219.

McElhinney, K; Smart, LR; Howard, TA; Power-Hays, A; Ware, RE. A Novel, Rapid, and Accurate Quantitative Hydroxyurea Assay. Blood. 2023; 142:2530.

McLean, TW; Borst, AJ; Hammill, AM; Iacobas, I; Atkinson, A; Shah, T; Margolin, JF; Bayliff, SL; Blatt, J. Practice Variations in Managing Infantile Hemangiomas. Journal of Pediatric Hematology/Oncology. 2023; 45:452-460.

Mujahid, H; Gupta, A; Hammill, A; Towe, CT; McCormack, FX. Complex Thoracic Lymphatic Disorders of Adults. Orphan Lung Diseases. : Springer Nature; Springer Nature; 2023.

Mullins, E; Larcey, R; Meisman, A; Mullins, T. PB1495 Comfort and Experiences Providing Care to Transgender Youth Among Hematologists in the Midwestern United States. Research and Practice in Thrombosis and Haemostasis. 2023; 7:101848.

Mullins, ES; Larcey, R; Meisman, A; Mullins, TL K. Attitudes of Hematologists in the Midwestern United States Toward Evaluating and Managing Thrombosis Risk in Transgender Youth Starting Gender Affirming Hormone Therapy. Blood. 2023; 142:3685.

Namazzi, R; Opoka, R; Conroy, AL; Datta, D; Tagoola, A; Bond, C; Goings, MJ; Ryu, MS; Cusick, SE; Krebs, NF; et al. Zinc for infection prevention in children with sickle cell anemia: a randomized double-blind placebo-controlled trial. Blood Advances. 2023; 7:3023-3031.

Ola, R; Hessels, J; Hammill, A; Friday, C; Clancy, M; Al-Samkari, H; Meadows, S; Iyer, V; Akhurst, R. Executive summary of the 14th HHT international scientific conference. Angiogenesis. 2023; 26:27-37.

Olupot-Olupot, P; Tomlinson, G; Williams, TN; Tshilolo, L; Santos, B; Smart, LR; McElhinney, K; Howard, TA; Aygun, B; Stuber, SE; et al. Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa. Blood. 2023; 141:1402-1410.

Peyvandi, F; Tarango, C; Simpson, M; Albisetti, M; Álvarez-Roman, MT; Chan, AK C; Curtin, J; Bystrická, L; Santagostino, E; Gresko, E; et al. Once-Weekly Efanesoctocog Alfa Prophylaxis Provided High Sustained Factor VIII Activity Levels, Independent of Blood Group, in Children <12 Years of Age with Severe Hemophilia A. Blood. 2023; 142:506.

Piel, FB; Rees, DC; DeBaun, MR; Nnodu, O; Ranque, B; Thompson, AA; Ware, RE; Abboud, MR; Abraham, A; Ambrose, EE; et al. Defining global strategies to improve outcomes in sickle cell disease: a Lancet Haematology Commission. The Lancet Haematology. 2023; 10:e633-e686.

Quinn, CT. Hydroxyurea: how much is enough?. Blood. 2023; 141:813-814.

Quinn, CT; Wiedmann, RT; Jarovsky, D; Lopez-Medina, E; Rodriguez, HM; Papa, M; Boggio, G; Shou, Q; Dagan, R; Richmond, P; et al. Safety and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine, in children with SCD: a V114-023 (PNEU-SICKLE) study. Blood Advances. 2023; 7:414-421.

Ramsey, LB; Prows, CA; Chidambaran, V; Sadhasivam, S; Quinn, CT; Teusink-Cross, A; Tang Girdwood, S; Dawson, DB; Vinks, AA; Glauser, TA. Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center. American Journal of Health-System Pharmacy. 2023; 80:852-859.

Rankine-Mullings, A; Keenan, R; Chakravorty, S; Inusa, B; Telfer, P; Velangi, M; Ware, RE; Moss, JJ; Lloyd, AL; Edwards, S; et al. Efficacy, safety, and pharmacokinetics of a new, ready-to-use, liquid hydroxyurea in children with sickle cell anemia. Blood Advances. 2023; 7:4319-4322.

Rankine-Mullings, AE; Soares, D; Aldred, K; Chang-Lopez, S; Wisdom-Phipps, ME; Schultz, W; Latham, TS; Stuber, SE; Jackson, P; Ware, RE; et al. Hydroxyurea Improves Intelligence Quotient Scores in Children with Sickle Cell Anemia and Elevated Transcranial Doppler Velocity. Blood. 2023; 142:797.

Rineer, S; Walsh, PS; Smart, LR; Harun, N; Schnadower, D; Lipshaw, MJ. Risk of Bacteremia in Febrile Children and Young Adults With Sickle Cell Disease in a Multicenter Emergency Department Cohort. JAMA Network Open. 2023; 6:e2318904.

Risinger, M; Kim, PS; Rodriguez, RX; Narvaez Rivas, M; Setchell, KD R; Zhang, W; Kalfa, TA. Hemolytic anemia and macrothrombocytopenia: A lipid problem?. American Journal of Hematology. 2023; 98:1335-1340.

Romano, L; Ntoumaziou, A; Gardner, JC; Stewart, M; Paulson, R; Salomonis, N; Blanc, L; Seu, K; Kalfa, TA. Leveraging Transcriptomic Data to Study Erythromyeloblastic Island (EMBI) Macrophages: Using Spic-GFP As a Marker for Embi Macrophages. Blood. 2023; 142:3832.

Romano, L; Seu, KG; Blanc, L; Kalfa, TA. Crosstalk between terminal erythropoiesis and granulopoiesis within their common niche: the erythromyeloblastic island. Current Opinion in Hematology. 2023; 30:99-105.

Sadaf, A; Dong, M; Korpik, J; Pfeiffer, A; Kalfa, TA; Latham, TS; Vinks, AA; Ware, RE; Quinn, CT. Effects of L-Glutamine on Biomarkers of Response in Sickle Cell Disease: A Pharmacokinetics-Pharmacodynamics Analysis. Blood. 2023; 142:1145.

Safeukui, I; Ware, RE; Mohandas, N; Haldar, K. Simultaneous adjunctive treatment of malaria and its coevolved genetic disorder sickle cell anemia. Blood Advances. 2023; 7:5970-5981.

Schrenk, S; Bischoff, LJ; Goines, J; Cai, Y; Vemaraju, S; Odaka, Y; Good, SR; Palumbo, JS; Szabo, S; Reynaud, D; et al. MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ. Nature Communications. 2023; 14:1929.

Sekyonda, Z; Kityo, C; Elgammal, Y; Kalfa, TA; Akkus, O; Gurkan, UA. Rapid Assessment of Hemoglobin-Oxygen Dissociation. Blood. 2023; 142:2270.

Sharma, B; Francisco, B; Rosenfeldt, L; Cantrell, R; Revenko, A; Monia, B; Flick, M; Palumbo, J. PB0708 The Tissue Factor/Thrombin Axis Limits Spontaneous Lymphatic Metastasis in Mice. Research and Practice in Thrombosis and Haemostasis. 2023; 7:101305.

Sharma, S; Ursery, LT; Bharathi, V; Miles, SD; Williams, WA; Elzawam, AZ; Schmedes, CM; Egnatz, GJ; Fernandez, JA; Palumbo, JS; et al. APC-PAR1-R46 signaling limits CXCL1 expression during poly IC-induced airway inflammation in mice. Journal of Thrombosis and Haemostasis. 2023; 21:3279-3282.

Shim, YJ; Sharma, BK; Hisada, Y; Mackman, N; Palumbo, JS; Diaz-Montero, C; Khorana, AA; McCrae, KR. Immune Checkpoint Blockade Promotes Thrombosis Via T-Cell and Neutrophil Activation, and Tumor-Cell Associated Tissue Factor (TF) in a Murine Model of Colorectal Cancer. Blood. 2023; 142:1192.

Sidonio,, RF; Bryant, PC; Di Paola, J; Hale, S; Heiman, M; Horowitz, GS; Humphrey, C; Jaffray, J; Joyner, LC; Kasthuri, R; et al. Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for mucocutaneous bleeding disorders. Expert Review of Hematology. 2023; 16:39-54.

Smart, LR; Ambrose, EE; Balyorugulu, G; Songoro, P; Shabani, I; Komba, P; Charles, M; Howard, TA; McElhinney, KE; O'Hara, SM; et al. Stroke Prevention with Hydroxyurea Enabled through Research and Education: A Phase 2 Primary Stroke Prevention Trial in Sub-Saharan Africa. Acta Haematologica. 2023; 146:95-105.

Smart, LR; Charles, M; McElhinney, KE; Dong, M; Power-Hays, A; Howard, T; Vinks, AA; Ambrose, EE; Ware, RE. Hydroxyurea pharmacokinetics and precision dosing in low-resource settings. Frontiers in Molecular Biosciences. 2023; 10:1130206.

Smart, LR; Segbefia, CI; Latham, TS; Stuber, SE; Amissah-Arthur, KN; Dzefi-Tettey, K; Lane, AC; Dei-Adomakoh, YA; Ware, RE. Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease. Trials. 2023; 24:603.

Strong, H; Hood, AM; Johnson, Y; Hackworth, R; Reed-Shackelford, M; Ramaswamy, R; Varughese, T; Quinn, CT; Crosby, LE. Using the consolidated framework for implementation research to identify recruitment barriers and targeted strategies for a shared decision-making randomized clinical trial in pediatric sickle cell disease. Clinical Trials. 2023; 20:211-222.

Tarango, C; Quinn, CT; Augsburger, B; Lucky, AW. Iron status and burden of anemia in children with recessive dystrophic epidermolysis bullosa. Pediatric Dermatology. 2023; 40:288-293.

Taylor, JM; Hammill, AM. The Role of Hereditary Hemorrhagic Telangiectasia in Neurologic Practice. Neurology. 2023; 100:1077-1078.

Teigen, D; Opoka, RO; Kasirye, P; Nabaggala, C; Hume, HA; Blomberg, B; John, CC; Ware, RE; Robberstad, B. Cost-Effectiveness of Hydroxyurea for Sickle Cell Anemia in a Low-Income African Setting: A Model-Based Evaluation of Two Dosing Regimens. Pharmacoeconomics Italian Research Articles. 2023; 41:1603-1615.

Teng, JM C; Hammill, A; Martini, J; Treat, J. Sirolimus in the Treatment of Microcystic Lymphatic Malformations: A Systematic Review. Lymphatic Research and Biology. 2023; 21:101-110.

Teoh, Z; Simpson, BN; Howard, T; McElhinney, K; Ware, R; Mena, R; Schlaudecker, EP. Codetection of Plasmodium falciparum in Children Hospitalized With Dengue Fever in the Dominican Republic. The Pediatric Infectious Disease Journal. 2023; 42:965-968.

Todd, K; Luchtman-Jones, L; Blackmore, A; Hennessey, C; McGrady, ME. Barriers to medication adherence in children, adolescents, and young adults prescribed anticoagulation. Pediatric Blood and Cancer. 2023; 70:e30076.

Torous, DK; Avlasevich, S; Bemis, JC; Howard, T; Ware, RE; Fung, C; Chen, Y; Sahsrabudhe, D; MacGregor, JT; Dertinger, SD. Lack of hydroxyurea-associated mutagenesis in pediatric sickle cell disease patients. Environmental and Molecular Mutagenesis. 2023; 64:167-175.

Tuff-Gordon, E; Faughnan, ME; Kim, H; Lawton, MT; Vozoris, NT; Brain Vascular Malformation Consortium HHT Investi, ; Brain Vascular Malformation Consortium HHT Investi, . An analysis of sex differences in pulmonary arteriovenous malformation presentation, complications and management in a large, multinational registry of patients with hereditary haemorrhagic telangiectasia. ERJ Open Research. 2023; 9:751-2022.

Tweddell, JS; Kharnaf, M; Zafar, F; Riggs, KW; Reagor, JA; Monia, BP; Revenko, A; Leino, DG; Owens, AP; Martin, JK; et al. Targeting the contact system in a rabbit model of extracorporeal membrane oxygenation. Blood Advances. 2023; 7:1404-1417.

Ware, J; Mcelhinney, K; Latham, T; Lane, A; Dienger-Stambaugh, K; Hildeman, D; Spearman, P; Ware, RE. Sustained and Boosted Antibody Responses in Breast Milk After Maternal SARS-CoV-2 Vaccination. Breastfeeding Medicine. 2023; 18:612-620.

Wilson, HP; Betensky, M; Miller, A; Amankwah, EK; Mosha, M; Fargo, JH; Mahajerin, A; Thornburg, C; Tarango, C; Acharya, S; et al. Use and Outcomes of Secondary Anticoagulation in Patients <21 Years Old Following Completion of a Primary Course of Anticoagulation for Treatment of Acute Provoked VTE: Findings from the Multinational Kids-DOTT Trial. Blood. 2023; 142:1275.

Yenwongfai, LN; Arora, R; Smith, AP; Kalfa, T; Husami, A; Radulescu, V; Myers, K; Lorsbach, R. Pediatric myelofibrosis due to compound heterozygous MPIG6B mutations in a patient of European ancestry. Pediatric Blood and Cancer. 2023; 70:e30023.

Yeom, SE; Cohen, B; Weiss, CR; Montano, C; Wohler, E; Sobreira, N; Hammill, AM; Comi, A. Genetic testing in the evaluation of individuals with clinical diagnosis of atypical Sturge-Weber syndrome. American Journal of Medical Genetics, Part A. 2023; 191:983-994.

Zhou, ZH; Cortese, MM; Fang, JL; Wood, R; Hummell, DS; Risma, KA; Norton, AE; KuKuruga, M; Kirshner, S; Rabin, RL; et al. Evaluation of association of anti-PEG antibodies with anaphylaxis after mRNA COVID-19 vaccination. Vaccine. 2023; 41:4183-4189.