Muglia Lab Publications

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Arnett MG, Pan MS, Doak W, Cyr PE, Muglia LM, Muglia LJ. The role of glucocorticoid receptor-dependent activity in the amygdala central nucleus and reversibility of early-life stress programmed behavior.  Transl Psychiatry. 2015 Apr 7;5:e542.

Swaggart KA, Pavlicev M, Muglia LJ. Genomics of preterm birth. Cold Spring Harb Perspect Med. 2015 Feb 2;5(2):a023127.

DeFranco EA, Seske LM, Greenberg JM, Muglia LJ. Influence of interpregnancy interval on neonatal morbidity. Am J Obstet Gynecol. 2015 Mar;212(3):386.e1-9.

Laryea G, Muglia L, Arnett M, Muglia LJ. Dissection of glucocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis by gene targeting in mice. Front Neuroendocrinol. 2015 Jan;36:150-64.

DeFranco EA, Ehrlich S, Muglia LJ . Influence of interpregnancy interval on birth timingBJOG. 2014 Dec; 121(13):1633-40.

Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD. Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasisMol Metab. 2014 Feb 19;3(4):394-407.

Wagner G, Kin K, Muglia L, Pavlicev M. Evolution of mammalian pregnancy and the origin of the decidual stromal cell. Int J Dev Biol. 2014; 58(2-4):117-26.

Steinhoff MC, MacDonald N, Pfeifer D, Muglia LJ. Influenza vaccine in pregnancy: policy and research strategies. Lancet. 2014 May 10;383(9929):1611-3.

Greenberg, JM, Muglia LJ. 50 years ago in The Journal of Pediatrics: The epidemiology of prematurityJ of Pediatr. 2014 Dec;165(6):1139.

Kamath-Rayne BD, Smith HC, Muglia LJ, Morrow AL. Amniotic Fluid: The Use of High-Dimensional Biology to Understand Fetal Well-Being. Reprod Sci. 2014 Jan;21(1):6-19.

Newman T, Lengyel C, Pavlicev M, Muglia LJ . Human evolution, genomics, and birth timing: new approaches for investigating preterm birth. NeoReviews. 2013; 15: e17.

Muglia LJ, Kumar D. Introduction to evolutionary genomic approaches to human disease. Applied and Translational Genomics. 2013; 2: 41.

Lackritz EM, Wilson CB, Guttmacher AE, Howse JL, Engmann CM, Rubens CE, Mason EM, Muglia LJ, Gravett MG, Goldenberg RL, Murray JC, Spong CY, Simpson JL. A solution pathway for preterm birth: accelerating a priority research agenda. Lancet Global Health. 2013 Dec;1(6):e328-30.

Kim J, Stirling KJ, Cooper ME, Ascoli M, Momany AM, McDonald EL, Ryckman KK, Rhea L, Schaa KL, Cosentino V, Gadow E, Saleme C, Shi M, Hallman M, Plunkett J, Teramo KA, Muglia LJ, Feenstra B, Geller F, Boyd HA, Melbye M, Marazita ML, Dagle JM, Murray JC. Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study. BMC Med Genet. 2013 Jul 26;14:77.

Laryea G, Schutz G, Muglia LJ. Disrupting hypothalamic glucocorticoid receptors causes HPA axis hyperactivity and excess adiposity. Mol Endocrinol. 2013 Oct;27(10):1655-65.

Chun S, Plunkett J, Teramo K, Muglia LJ, Fay JC. Fine-mapping an association of FSHR with preterm birth in a Finnish population. PLoS ONE. 2013 Oct 29;8(10):e78032.

Louderback K, Wills TA, Muglia LJ, Winder DG. Knockdown of BNST Glu2B-containing NMDA receptors mimics the actions of ketamine on novelty-induced hypophagia. Translational Psychiatry. 2013 Dec 3;3:e331.

Zhang G, Muglia LJ, Chakraborty R, Akey JM, Williams SM. Signatures of natural selection on genetic variants affecting complex human traits. Applied and Translational Genomics 2013; 2:77-93.

Bezold KY, Karjalainen MK, Hallman M, Teramo K, Muglia LJ. The genomics of preterm birth: from animal models to human studies. Genome Med. 2013 Apr 29;5(4):34.

Defranco EA, Valent AM, Newman T, Regan J, Smith J, Muglia LJ. Adjunctive therapies to cerclage for the prevention of preterm birth: a systematic review. Obstet Gynecol Int. 2013; 2013:528158.

McElroy JJ, Gutman CE, Shaffer CM, Busch TD, Puttonen H, Teramo K, Murray JC, Hallman M, Muglia LJ. Maternal coding variants in complement receptor 1 and spontaneous idiopathic preterm birthHum Genet. 2013 Aug;132(8):935-42.

McGregor TL, Van Driest SL, Brothers KB, Bowton EA, Muglia LJ, Roden DM. Inclusion of pediatric samples in an opt-out biorepository linking DNA to de-identified medical records: pediatric BioVUClin Pharmacol Ther. 2013 Feb;93(2):204-11.

Laryea G, Arnett MG, Wieczorek L, Muglia LJ. Site-specific modulation of brain glucocorticoid receptor and corticotropin-releasing hormone expression using lentiviral vectors. Mol Cell Endocrinol. 2013 May 22;371(1-2):160-5.

Bream EN, Leppellere CR, Cooper ME, Dagle JM, Merrill DC, Christensen K, Simhan HN, Fong CT, Hallman M, Muglia LJ, Marazita ML, Murray JC. Candidate gene linkage approach to identify DNA variants that predispose to preterm birth. Pediatr Res. 2013 Feb;73(2):135-41.

Falah N, McElroy J, Snegovskikh V, Lockwood CJ, Norwitz E, Murray JC, Kuczynski E, Menon R, Teramo K, Muglia LJ, Morgan T. Investigation of genetic risk factors for chronic adult diseases for association with preterm birth. Hum Genet. 2013 Jan; 132(1):57-67.

Schug TT, Erlebacher A, Leibowitz S, Ma L, Muglia LJ, Rando OJ, Rogers JM, Romero R, vom Saal FS, Wise DL. Fetal programming and environmental exposures: implications for prenatal care and preterm birth. Ann N Y Acad Sci. 2012 Dec; 1276:37-46.

Karjalainen MK, Huusko JM, Ulvila J, Sotkasiira J, Luukkonen A, Teramo K, Plunkett J, Anttila V, Palotie A, Haataja R, Muglia LJ, Hallman M. A potential novel spontaneous preterm birth gene, AR, identified by linkage and association analysis of X chromosomal markers. PLoS One. 2012; 7(12):e51378.

Laryea G, Arnett MG, Muglia LJ. Behavioral Studies and Genetic Alterations in Corticotropin-Releasing Hormone (CRH) Neurocircuitry: Insights into Human Psychiatric Disorders. Behav Sci (Basel). 2012 Jun 21; 2(2):135-171.

Kocalis HE, Turney MK, Printz RL, Laryea GN, Muglia LJ, Davies SS, Stanwood GD, McGuinness OP, Niswender KD. Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity. PLoS One. 2012;7(8):e42981.

Wieczorek L, Majumdar D, Wills TA, Hu L, Winder DG, Webb DJ, Muglia LJ. Absence of Ca2+-stimulated adenylyl cyclases leads to reduced synaptic plasticity and impaired experience-dependent fear memory. Transl Psychiatry. 2012 May 29;2:e126.

Ratajczak CK, Asada M, Allen GC, McMahon DG, Muglia LM, Smith D, Bhattacharyya S, Muglia LJ. Generation of myometrium-specific Bmal1 knockout mice for parturition analysis. Reprod Fertil Dev. 2012;24(5):759-67.

Kavaliers M, Clipperton-Allen A, Cragg CL, Gustafsson JÅ, Korach KS, Muglia L, Choleris E. Male risk taking, female odors, and the role of estrogen receptors. Physiol Behav. 2012 Dec 5;107(5):751-61.

Dong H, Murphy KM, Meng L, Montalvo-Ortiz J, Zeng Z, Kolber BJ, Zhang S, Muglia LJ, Csernansky JG. Corticotrophin releasing factor accelerates neuropathology and cognitive decline in a mouse model of Alzheimer's disease. J Alzheimers Dis. 2012; 28(3):579-92.

McElroy JJ, Muglia LJ, Morgan TM. Better by the pound: the genetics of birth weight. J Pediatr. 2012 Jan;160(1):3-4.

Dong H, Murphy KM, Meng L, Montalvo-Ortiz J, Zeng Z, Kolber BJ, Zhang S, Muglia LJ, Csernansky JG. Corticotrophin Releasing Factor Accelerates Neuropathology and Cognitive Decline in a Mouse Model of Alzheimer’s Disease. J Alzheimers Dis. 2011 Nov 1.

McGregor TL, Gurnett CA, Dobbs MB, Wise CA, Morcuende JA, Morgan TM, Menon R, Muglia LJ. Common polymorphisms in human lysyl oxidase genes are not associated with the adolescent idiopathic scoliosis phenotype.  BMC Med Genet. 2011 Jul 8;12:92.

Bhattacharyya S, Zhao Y, Kay TW, Muglia LJ. Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9554-9.

Defranco EA, Jacobs TS, Plunkett J, Chaudhari BP, Huettner PC, Muglia LJ. Placental pathologic aberrations in cases of familial idiopathic spontaneous preterm birth. Placenta. 2011 May;32(5):386-90. doi: 10.1016/j. placenta. 2011.02.010.

Arnett MG, Kolber BJ, Boyle MP, Muglia LJ. Behavioral insights from mouse models of forebrain and amygdala-specific glucocorticoid receptor genetic disruption. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):2-5.

Plunkett J, Doniger S, Orabona G, Morgan T, Haataja R, Hallman M, Puttonen H, Menon R, Kuczynski E, Norwitz E, Snegovskikh V, Palotie A, Peltonen L, Fellman V, DeFranco EA, Chaudhari BP, McGregor TL, McElroy JJ, Oetjens MT, Teramo K, Borecki I, Fay J, Muglia L. An evolutionary genomic approach to identify genes involved in human birth timing. PLoS Genet. 2011 Apr;7(4):e1001365.

Haataja R, Karjalainen MK, Luukkonen A, Teramo K, Puttonen H, Ojaniemi M, Varilo T, Chaudhari BP, Plunkett J, Murray JC, McCarroll SA, Peltonen L, Muglia LJ, Palotie A, Hallman M. Mapping a new spontaneous preterm birth susceptibility gene, IGF1R, using linkage, haplotype sharing, and association analysis. PLoS Genet. 2011 Feb 3;7(2):e1001293.

Liu Q, Zhang J, Zerbinatti C, Zhan Y, Kolber BJ, Herz J, Muglia LJ, Bu G. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. PLoS Biol. 2011 Jan 11;9(1):e1000575.