Zhang Pregnancy Genomics Lab

Sole-Navais, P; Bacelis, J; Helgeland, Ø; Modzelewska, D; Vaudel, M; Flatley, C; Andreassen, O; Njølstad, PR; Muglia, LJ; Johansson, S; et al. Autozygosity mapping and time-to-spontaneous delivery in Norwegian parent-offspring trios. Human Molecular Genetics. 2021; 29:3845-3858.

Solé-Navais, P; Brantsæter, AL; Caspersen, IH; Lundh, T; Muglia, LJ; Meltzer, HM; Zhang, G; Jacobsson, B; Sengpiel, V; Barman, M. Maternal Dietary Selenium Intake during Pregnancy Is Associated with Higher Birth Weight and Lower Risk of Small for Gestational Age Births in the Norwegian Mother, Father and Child Cohort Study. Nutrients. 2021; 13.

Rokas, A; Mesiano, S; Tamam, O; Labella, A; Zhang, G; Muglia, L. Developing a theoretical evolutionary framework to solve the mystery of parturition initiation. eLife. 2020; 9.

Sakabe, NJ; Aneas, I; Knoblauch, N; Sobreira, DR; Clark, N; Paz, C; Horth, C; Ziffra, R; Kaur, H; Liu, X; et al. Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth. Science advances. 2020; 6.

LaBella, AL; Abraham, A; Pichkar, Y; Fong, SL; Zhang, G; Muglia, LJ; Abbot, P; Rokas, A; Capra, JA. Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci. Nature Communications. 2020; 11.

Modzelewska, D; Sole-Navais, P; Sandstrom, A; Zhang, G; Muglia, LJ; Flatley, C; Nilsson, S; Jacobsson, B. Changes in data management contribute to temporal variation in gestational duration distribution in the Swedish Medical Birth Registry. PLoS ONE. 2020; 15.

Chen, J; Bacelis, J; Sole-Navais, P; Srivastava, A; Juodakis, J; Rouse, A; Hallman, M; Teramo, K; Melbye, M; Feenstra, B; et al. Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother-infant pairs. PLoS Medicine. 2020; 17.

Modzelewska, D; Sole-Navais, P; Zhang, G; Muglia, LJ; Nilsson, S; Jacobsson, B. Importance of the environment for gestational duration variability and correlation between relatives - results from the Medical Swedish Birth Registry, 1973-2012. PLoS ONE. 2020; 15.

Barman, M; Brantsaerer, AL; Nilsson, S; Haugen, M; Lundh, T; Jr, CG F; Zhang, G; Muglia, LJ; Meltzer, HM; Jacobsson, B; et al. Maternal dietary selenium intake is associated with increased gestational length and decreased risk of preterm delivery. British Journal of Nutrition. 2020; 123:209-219.

Robinson, JR; Carroll, RJ; Bastarache, L; Chen, Q; Mou, Z; Wei, W; Connolly, JJ; Mentch, F; Sleiman, P; Crane, PK; et al. Association of Genetic Risk of Obesity with Postoperative Complications Using Mendelian Randomization. World Journal of Surgery. 2020; 44:84-94.

Liu, X; Helenius, D; Skotte, L; Beaumont, RN; Wielscher, M; Geller, F; Juodakis, J; Mahajan, A; Bradfield, JP; Lin, FT; et al. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nature Communications. 2019; 10.

Monangi, NK; Zhang, G; Hallman, M; Teramo, K; Jacobsson, B; Muglia, LJ. Maternal genome and pregnancy outcomes. New Technologies and Perinatal Medicine. 2019.

Chen, A; Jandarov, R; Zhou, L; Calafat, AM; Zhang, G; Urbina, EM; Sarac, J; Augustin, DH; Caric, T; Bockor, L; et al. Association of perfluoroalkyl substances exposure with cardiometabolic traits in an island population of the eastern Adriatic coast of Croatia. Science of the Total Environment. 2019; 683:29-36.

Warrington, NM; Beaumont, RN; Horikoshi, M; Day, FR; Helgeland, O; Laurin, C; Bacelis, J; Peng, S; Hao, K; Feenstra, B; et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. 2019; 51:804-814.

Hallman, M; Haapalainen, A; Huusko, JM; Karjalainen, MK; Zhang, G; Muglia, LJ; Ramet, M. Spontaneous premature birth as a target of genomic research. Pediatric Research. 2019; 85:422-431.

Chen, J; Xu, H; Jegga, A; Zhang, K; White, PS; Zhang, G. Novel phenotype-disease matching tool for rare genetic diseases. Genetics in Medicine. 2019; 21:339-346.

Nebert, DW; Zhang, G. Pharmacogenomics. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics: Foundations. 2019.

Nebert, DW; Zhang, G. 16 Pharmacogenomics. Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics. 2019.

Rappoport, N; Toung, J; Hadley, D; Wong, RJ; Fujioka, K; Reuter, J; Abbott, CW; Oh, S; Hu, D; Eng, C; et al. A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Scientific Reports. 2018; 8.

Sirota, M; Thomas, CG; Liu, R; Zuhl, M; Banerjee, P; Wong, RJ; Quaintance, CC; Leite, R; Chubiz, J; Anderson, R; et al. Enabling precision medicine in neonatology, an integrated repository for preterm birth research. Scientific data. 2018; 5.

Bacelis, J; Juodakis, J; Waldorf, KM A; Sengpiel, V; Muglia, LJ; Zhang, G; Jacobsson, B. Uterine distention as a factor in birth timing: retrospective nationwide cohort study in Sweden. BMJ Open. 2018; 8.

Zhang, G; Srivastava, A; Bacelis, J; Juodakis, J; Jacobsson, B; Muglia, LJ. Genetic studies of gestational duration and preterm birth. Best Practice and Research in Clinical Obstetrics and Gynaecology. 2018; 52:33-47.

Huusko, JM; Karjalainen, MK; Graham, BE; Zhang, G; Farrow, EG; Miller, NA; Jacobsson, B; Eidem, HR; Murray, JC; Bedell, B; et al. Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth. PLoS Genetics. 2018; 14.

Zhang, G; Feenstra, B; Bacelis, J; Liu, X; Muglia, LM; Juodakis, J; Miller, DE; Litterman, N; Jiang, PP; Russell, L; et al. Genetic Associations With Gestational Duration and Spontaneous Preterm Birth. 2018; 38.

Zhang, G; Feenstra, B; Bacelis, J; Liu, X; Muglia, LM; Juodakis, J; Miller, DE; Litterman, N; Jiang, PP; Russell, L; et al. Genetic Associations With Gestational Duration and Spontaneous Preterm Birth. 2018; 38.

Beaumont, RN; Warrington, NM; Cavadino, A; Tyrrell, J; Nodzenski, M; Horikoshi, M; Geller, F; Myhre, R; Richmond, RC; Paternoster, L; et al. Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics. 2018; 27:742-756.

Zhang, G; Feenstra, B; Bacelis, J; Liu, X; Muglia, LM; Juodakis, J; Miller, DE; Litterman, N; Jiang, P; Russell, L; et al. Genetic Associations With Gestational Duration and Spontaneous Preterm Birth. Obstetrical and Gynecological Survey. 2018; 73:83-85.

Mohanty, V; Zhang, G; Komurov, K. Pan-Cancer Analysis of Heritable Genetic Variations Reveals Cancer-Specific Activation of Dormant Oncogenic Pathways. 2018.

Zhang, G; Feenstra, B; Bacelis, J; Liu, X; Muglia, LM; Juodakis, J; Miller, DE; Litterman, N; Jiang, P; Russell, L; et al. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. New England Journal of Medicine. 2017; 377:1156-1167.

Zhang, G; Nebert, DW. Personalized medicine: Genetic risk prediction of drug response. Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and. 2017; 175:75-90.

Juodakis, J; Bacelis, J; Zhang, G; Muglia, LJ; Jacobsson, B. Time-Variant Genetic Effects as a Cause for Preterm Birth: Insights from a Population of Maternal Cousins in Sweden. G3: Genes, Genomes, Genetics. 2017; 7:1349-1356.