Zhang Pregnancy Genomics Lab

Publications

Srivastava, AK; Juodakis, J; Sole-Navais, P; Chen, J; Bacelis, J; Teramo, K; Hallman, M; Njølstad, PR; Evans, DM; Jacobsson, B; Muglia, LJ; Zhang, G. Haplotype-based analysis distinguishes maternal-fetal genetic contribution to pregnancy-related outcomes. Editor, Cordell HJ. PLoS Genetics. 2025; 21:e1011575.

Sebastião, YV; Thiruvengadam, R; Khanam, R; Mehmood, U; Pervin, J; Ayushi, ; Desiraju, BK; Kabole, F; Ahmed, S; Aktar, S; Jehan, F; Baqui, AH; Stringer, JS A; Bhatnagar, S. Association between gestational weight gain and adverse pregnancy outcomes: cohort analysis from South Asia and Sub-Saharan Africa. 2025; 3:e000900.

Robinson, JF; Das, S; Khan, W; Khanam, R; Price, JT; Rahman, A; Ahmed, S; Ali, SM; Deb, S; Deveale, B; Jehan, F; Sazawal, S; Stringer, JS A; Fisher, SJ. High rates of placental inflammation among samples collected by the Multi-Omics for Mothers and Infants consortium. American Journal of Obstetrics and Gynecology. 2025; 232:230.e1-230.e19.

Pavličev, M; McDonough-Goldstein, CE; Zupan, AM; Muglia, L; Hu, YC; Kong, F; Monangi, N; Dagdas, G; Zupančič, N; Maziarz, J; Sinner, D; Zhang, G; Wagner, G; Muglia, L. A common allele increases endometrial Wnt4 expression, with antagonistic implications for pregnancy, reproductive cancers, and endometriosis. Nature Communications. 2024; 15:1152.

Xu, H; Zhang, G; Chen, J. A novel method for cell deconvolution using DNA methylation in PCA space. BMC Genomics. 2024; 25:798.

Solé-Navais, P; Juodakis, J; Ytterberg, K; Wu, X; Bradfield, JP; Vaudel, M; LaBella, AL; Helgeland, Ø; Flatley, C; Geller, F; Muglia, LJ; Johansson, S; Zhang, G; Jacobsson, B. Genome-wide analyses of neonatal jaundice reveal a marked departure from adult bilirubin metabolism. Nature Communications. 2024; 15:7550.

Srivastava, AK; Monangi, N; Ravichandran, V; Solé-Navais, P; Jacobsson, B; Muglia, LJ; Zhang, G. Recent Advances in Genomic Studies of Gestational Duration and Preterm Birth. Clinics in Perinatology. 2024; 51:313-329.

Monangi, NK; Xu, H; Fan, YM; Khanam, R; Khan, W; Deb, S; Pervin, J; Price, JT; Kaur, L; Villar, J; Stringer, JS A; Ashorn, P; Zhang, G; Muglia, LJ. Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis. American Journal of Clinical Nutrition. 2024; 119:221-231.

Wang, L; Rossi, RM; Chen, X; Chen, J; Runyon, J; Chawla, M; Miller, D; Forney, C; Lynch, A; Zhang, X; Kottyan, LC; Weirauch, MT; Zhang, G; Muglia, LJ. A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth. BMC Medicine. 2023; 21:258.

Beaumont, RN; Flatley, C; Vaudel, M; Wu, X; Chen, J; Moen, GH; Skotte, L; Helgeland, Ø; Solé-Navais, P; Banasik, K; Johansson, S; Freathy, RM; Feenstra, B; Njølstad, PR. Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth. Nature Genetics. 2023; 55:1807-1819.

Pasanen, A; Karjalainen, MK; Zhang, G; Tiensuu, H; Haapalainen, AM; Ojaniemi, M; Feenstra, B; Jacobsson, B; Palotie, A; Laivuori, H; Muglia, LJ; Rämet, M; Hallman, M. Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. Editor, Lynch VJ. PLoS Genetics. 2023; 19:e1010982.

Ge, X; Schulze, K; Stephenson, K; Wu, LS-F; Baker, S; Ali, H; Shaikh, S; Monangi, N; Zhang, G; Landero, J; West, K; Christian, P. P07-023-23 Human Milk Zinc, Copper, and Selenium Concentrations at 3 Months Postpartum Among Bangladeshi Women: Associations With Maternal Plasma Mineral Concentrations. Current Developments in Nutrition. 2023; 7:101014.

Sincerbeaux, G; Schulze, K; Kim, H; Baker, S; Wu, LS F; Rebholz, C; Gogain, J; Cuddeback, L; Monangi, N; Zhang, G; West, K. P07-054-23 A Plasma Cuprome Reveals the Biology and Status of Copper in 1st Trimester Pregnant Women in Rural Bangladesh. Current Developments in Nutrition. 2023; 7:101045.

Solé-Navais, P; Flatley, C; Steinthorsdottir, V; Vaudel, M; Juodakis, J; Chen, J; Laisk, T; LaBella, AL; Westergaard, D; Bacelis, J; Freathy, RM; Johanson, S; Zhang, G; Jacobsson, B. Genetic effects on the timing of parturition and links to fetal birth weight. Nature Genetics. 2023; 55:559-567.

Srivastava, AK; Williams, SM; Zhang, G. Heritability Estimation Approaches Utilizing Genome-Wide Data. Current Protocols. 2023; 3:e734.

Sprague, AC; Niu, L; Jandarov, R; Zhang, X; Zhang, G; Chen, A; Šarac, J; Čoklo, M; Missoni, S; Rudan, P; Langevin, SM; Deka, R. Stable methylation loci are associated with systolic blood pressure in a Croatian island population. Epigenomics. 2022; 14:1343-1354.

Robinson, JR; Carroll, RJ; Bastarache, L; Chen, Q; Pirruccello, J; Mou, Z; Wei, WQ; Connolly, J; Mentch, F; Crane, PK; Weng, C; Roden, D; Khera, AV; Denny, JC. Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics. Obesity. 2022; 30:2477-2488.

Muglia, LJ; Monangi, N; Hallman, M; Teramo, K; Jacobsson, B; Zhang, G. Preventing Spontaneous Preterm Birth: Insights from Genomics. 2022; 1:108-123.

Yang, Z; Shikany, A; Ni, Y; Zhang, G; Weaver, KN; Chen, J. Using deep learning and electronic health records to detect Noonan syndrome in pediatric patients. Genetics in Medicine. 2022; 24:2329-2337.

Jain, VG; Monangi, N; Zhang, G; Muglia, LJ. Genetics, epigenetics, and transcriptomics of preterm birth. American journal of reproductive immunology and microbiology : AJRIM. 2022; 88:e13600.

Chen, J; Navais, PS; Xu, H; Flatley, C; Bacelis, J; Monangi, N; Kacerovsky, M; Hallman, M; Teramo, K; Lawlor, D; Murray, J; Jacobsson, B; Muglia, L; Zhang, G. Interrogating the causal effects of maternal circulating CRP on gestational duration and birth weight. 2022; 2022.05.16.22275164.

Haskell, MJ; Maleta, K; Arnold, CD; Jorgensen, JM; Fan, YM; Ashorn, U; Matchado, A; Monangi, NK; Zhang, G; Xu, H; Muglia, LJ; Hallman, M; Ashorn, P; Dewey, KG. Provision of Small-Quantity Lipid-Based Nutrient Supplements Increases Plasma Selenium Concentration in Pregnant Women in Malawi: A Secondary Outcome of a Randomized Controlled Trial. Current Developments in Nutrition. 2022; 6:nzac013.

Huusko, JM; Tiensuu, H; Haapalainen, AM; Pasanen, A; Tissarinen, P; Karjalainen, MK; Zhang, G; Christensen, K; Ryckman, KK; Jacobsson, B; Murray, JC; Kingsmore, SF; Hallman, M; Muglia, LJ; Rämet, M. Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth. Scientific Reports. 2021; 11:17115.

Eric, V; Yi, V; Murdock, D; Kalla, SE; Wu, TJ; Sabo, A; Li, S; Meng, Q; Tian, X; Murugan, M; Harley, J; Harr, M; Hartzler, A; Hayes, MG. Neptune: an environment for the delivery of genomic medicine. Genetics in Medicine. 2021; 23:1838-1846.

Care, AG; Gupta, JK; Goodfellow, L; Zhang, G; Monangi, N; Belling, E; Landero, J; Chappell, J; Sharp, A; Alfirevic, A; Müller-Myhsok, B; Muglia, LJ; Alfirevic, Z. Maternal selenium levels and whole genome screen in recurrent spontaneous preterm birth population: A nested case control study. European Journal of Obstetrics Gynecology and Reproductive Biology. 2021; 265:203-211.

Monangi, N; Xu, H; Khanam, R; Khan, W; Deb, S; Pervin, J; Price, JT; Kennedy, SH; Al Mahmud, A; Fan, Y; Sazawal, S; Stringer, J; Zhang, G; Muglia, L. Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis. BMJ Global Health. 2021; 6:e005856.

Sole-Navais, P; Bacelis, J; Helgeland, Ø; Modzelewska, D; Vaudel, M; Flatley, C; Andreassen, O; Njølstad, PR; Muglia, LJ; Johansson, S; Zhang, G; Jacobsson, B. Autozygosity mapping and time-to-spontaneous delivery in Norwegian parent-offspring trios. Human Molecular Genetics. 2021; 29:3845-3858.

Solé-Navais, P; Brantsæter, AL; Caspersen, IH; Lundh, T; Muglia, LJ; Meltzer, HM; Zhang, G; Jacobsson, B; Sengpiel, V; Barman, M. Maternal Dietary Selenium Intake during Pregnancy Is Associated with Higher Birth Weight and Lower Risk of Small for Gestational Age Births in the Norwegian Mother, Father and Child Cohort Study. Nutrients. 2021; 13:E23.