Vorhees / Williams Lab
Publications

Publications

Williams, MT; Gutierrez, A; Vorhees, CV. Effects of Acute Deltamethrin Exposure in Adult and Developing Sprague Dawley Rats on Acoustic Startle Response in Relation to Deltamethrin Brain and Plasma Concentrations. Toxicological Sciences. 2019; 168(1):61-69.

Williams, MT; Braun, AA; Amos-Kroohs, RM; Mcallister, JP; Lindquist, DM; Mangano, FT; Vorhees, CV; Yuan, W. Kaolin-induced ventriculomegaly at weaning produces long-term learning, memory, and motor deficits in rats. International Journal of Developmental Neuroscience. 2014; 35:7-15.

Grace, CE; Schaefer, TL; Gudelsky, GA; Williams, MT; Vorhees, CV. Neonatal methamphetamine-induced corticosterone release in rats is inhibited by adrenal autotransplantation without altering the effect of the drug on hippocampal serotonin. Neurotoxicology and Teratology. 2010; 32(3):356-361.

Williams, MT; Schaefer, TL; Furay, AR; Ehrman, LA; Vorhees, CV. Ontogeny of the adrenal response to (+)-methamphetamine in neonatal rats: the effect of prior drug exposure. Stress. 2006; 9(3):153-163.

Williams, MT; Brown, RW; Vorhees, CV. Neonatal methamphetamine administration induces region-specific long-term neuronal morphological changes in the rat hippocampus, nucleus accumbens and parietal cortex. European Journal of Neuroscience. 2004; 19(12):3165-3170.

Williams, MT; Hennessy, MB; Davis, HN. CRF administered to pregnant rats alters offspring behavior and morphology. Pharmacology Biochemistry and Behavior. 1995; 52(1):161-167.

Magnusen, AF; Hopkin, RJ; Vorhees, C; Wilson, E; Moehlman, M; Hallinan, B; Erickson, C; Delbello, MP; Marsili, L; Coufal, NG; Pandey, MK. Emerging role of complement system in the induction of neuroinflammation in adenylosuccinate lyase deficiency disorder. Brain, Behavior, & Immunity - Health. 2025; 48:101091.

Brewer, LM; Patel, J; Andrasik, F; Sable, JJ; Williams, MT; Vorhees, CV; Sable, HJK. Auditory Event-Related Potentials in Two Rat Models of Attention-Deficit Hyperactivity Disorder: Evidence of Automatic Attention Deficits in Spontaneously Hypertensive Rats but Not in Latrophilin-3 Knockout Rats. Genes. 2025; 16(6).

Raje, KR; Williams, MT; Vorhees, CV. Comparison of Sprague Dawley with Long Evans rats on a battery of widely used neurobehavioral tests. Physiology and Behavior. 2025; 294:114860.

Vorhees, C; Fritz, A; Gollaway, B; Williams, M. Gene x environment interaction between heterozygous deletion of the ADHD risk gene latrophilin-3 (Lphn3) and developmental deltamethrin exposure in Sprague Dawley rats. Neurotoxicology and Teratology. 2025; 109:107492.

Williams, MT; Regan, SL; Fritz, AL; Gollaway, BM; Mascia, AE; Vatner, RE; Perentesis, JP; Vorhees, CV. Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats. Scientific Reports. 2025; 15(1):10602.

Sable, HJK; Paige, NB; Nalan, PA; Pace, RL; Hicks, CB; Regan, SL; Williams, MT; Vorhees, CV; Lester, DB. Phasic dopamine release in two different rat models of attention-deficit/hyperactivity disorder: Spontaneously hypertensive rats (SHR) versus Lphn3 knockout rats. Neuroscience. 2025; 567:150-162.

Vorhees, CV; Fritz, AL; Gollaway, BM; Williams, MT. Gene × environment interaction between heterozygous deletion of the ADHD risk gene latrophilin-3 (adgrl3) and developmental deltamethrin exposure in Sprague Dawley rats. Neurotoxicology and Teratology. 2025; 108:107435.

Vorhees, CV; Sugimoto, C; Regan, SL; Pitzer, EM; Fritz, AL; Gollaway, BM; Sertorio, M; Mascia, AE; Vatner, RE; Parentesis, JP; Williams, MT. 3174: Effects of whole brain conventional or FLASH proton irradiation in Sprague Dawley rats. Radiotherapy and Oncology. 2024; 194:s5308-s5310.

Sugimoto, C; Perna, MK; Regan, SL; Tepe, EA; Liou, R; Fritz, AL; Williams, MT; Vorhees, CV; Skelton, MR. A Gad2 specific Slc6a8 deletion recapitulates the contextual and cued freezing deficits seen in Slc6a8-/y mice. Brain Research. 2024; 1825:148690.

Vorhees, CV; Williams, MT. Tests for learning and memory in rodent regulatory studies. Current Research in Toxicology. 2024; 6:100151.

Vorhees, CV; Amos-Kroohs, RM; Williams, MT. Long-term effects of Preweaning environmental impoverishment on neurobehavioral and neurocognitive outcomes in Sprague Dawley rats: An early environmental stress model. Neurotoxicology and Teratology. 2024; 103:107356.

Bromley, R; Graz, MB; Bluett-Duncan, M; Chambers, C; Damkier, P; Dietrich, K; Dolk, H; Grant, K; Mattson, S; Meador, K; Yates, L; Ystrom, E; Supraja, TA; Adams, J. Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies. Neurotoxicology and Teratology. 2023; 98:107203.

Vorhees, CV. Concern over differences between experimental design and data analyses in Jones et al. Proceedings of the National Academy of Sciences of the United States of America. 2023; 120(24):e2302944120.

Bromley, RL; Bickle Graz, M; Bluett-Duncan, M; Chambers, C; Damkier, P; Dietrich, K; Dolk, H; Grant, K; Mattson, S; Meador, KJ; Yates, L; Ystrom, E; Supraja, TA; Adams, J. Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies. Frontiers in Pharmacology. 2023; 14:1094698.

Williams, M; Sugimoto, C; Regan, S; Pitzer, E; Fritz, A; Sertorio, M; Mascia, A; Vatner, R; Perentesis, J; Vorhees, C. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. Neurotoxicology and Teratology. 2023; 98:107276.

Vorhees, C; Fritz, A; Gollaway, B; Williams, M. Interaction of latrophilin-3, an ADHD risk gene, and deltamethrin in Sprague Dawley rats on learning and memory. Neurotoxicology and Teratology. 2023; 98:107271.

Carbajal, MS; Bounmy, AJC; Harrison, OB; Nolen, HG; Regan, SL; Williams, MT; Vorhees, CV; Sable, HJK. Impulsive choice in two different rat models of ADHD-Spontaneously hypertensive and Lphn3 knockout rats. Frontiers in Neuroscience. 2023; 17:1094218.

Zoubovsky, SP; Williams, MT; Hoseus, S; Tumukuntala, S; Riesenberg, A; Schulkin, J; Vorhees, CV; Campbell, K; Lim, HW; Muglia, LJ. Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment. Translational Psychiatry. 2022; 12(1).

Zoubovsky, SP; Williams, MT; Hoseus, S; Tumukuntala, S; Riesenberg, A; Schulkin, J; Vorhees, CV; Campbell, K; Lim, H-W; Muglia, LJ. Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment. Translational Psychiatry. 2022; 12(1).

Regan, SL; Sugimoto, C; Dawson, HE; Williams, MT; Vorhees, CV. Latrophilin-3 heterozygous versus homozygous mutations in Sprague Dawley rats: Effects on egocentric and allocentric memory and locomotor activity. Genes, Brain and Behavior. 2022; 21(7):e12817.

Zoubovsky, SP; Williams, MT; Hoseus, S; Tumukuntala, S; Riesenberg, A; Schulkin, J; Vorhees, CV; Campbell, K; Lim, H-W; Muglia, LJ. Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment. Translational Psychiatry. 2022; 12(1):22.

Regan, SL; Williams, MT; Vorhees, CV. Review of rodent models of attention deficit hyperactivity disorder. Neuroscience and Biobehavioral Reviews. 2022; 132:621-637.

Upton, BA; Nayak, G; Schweinzger, I; D'souza, SP; Vorhees, CV; Williams, MT; Earl, BR; Lang, RA. Comprehensive Behavioral Analysis of Opsin 3 (Encephalopsin)-Deficient Mice Identifies Role in Modulation of Acoustic Startle Reflex. eNeuro. 2022; 9(5).

Williams, MT; Sugimoto, C; Regan, SL; Pitzer, EM; Fritz, AL; Sertorio, M; Mascia, AE; Vatner, RE; Perentesis, JP; Vorhees, CV. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. PLoS ONE. 2022; 17(9):e0274007.

Pitzer, EM; Sugimoto, C; Regan, SL; Gudelsky, GA; Williams, MT; Vorhees, CV. Developmental deltamethrin: Sex-specific hippocampal effects in Sprague Dawley rats. Current Research in Toxicology. 2022; 3:100093.

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