Ultra-high dose-rate proton FLASH improves tumor control. Radiotherapy and Oncology. 2023; 186:109741..
2023; 98:107276.. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. Neurotoxicology and Teratology.
Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR). Journal of Neuro-Oncology. 2023; 162:353-362..
Use of gemcitabine, oxaliplatin, and anti-CD20 therapy in children and adolescents with non-Hodgkin lymphoma unfit for intensive therapy. Pediatric Blood and Cancer. 2023; 70:e30214..
Barriers to medication adherence among adolescents and young adults with cancer. Pediatric Blood and Cancer. 2023; 70:e30186..
Data standards in pediatric oncology: Past, present, and future. Pediatric Blood and Cancer. 2023; 70:e30128..
Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial. JAMA oncology. 2023; 9:62-69..
FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study. JMIR Research Protocols. 2023; 12:e41812..
Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis. Nature. 2022; 612:787-794..
2022; 114:1074.. Neurocognitive outcomes in pediatric brain tumor survivors treated with proton radiotherapy: a study from the Pediatric Proton/Photon Consortium Registry (PPCR). International Journal of Radiation: Oncology - Biology - Physics.
2022; 140:10693-10694.. High Throughput Pre-Clinical Models to Determine a Synergistic Molar Ratio of 5-Azacitidine to Venetoclax and Uncover Resistance Mechanisms to 5-Azacitidine and Venetoclax Combination Therapy in Acute Myeloid Leukemia. Blood.
2022; 114:s4.. FAST-01: Results of the First-in-Human Study of Proton FLASH Radiotherapy. International Journal of Radiation: Oncology - Biology - Physics.
Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. Editor, Lee J. PloS one. 2022; 17:e0274007..
US News & World Report and quality metrics: Inclusion of sickle cell disease is a matter of equity. Pediatric Blood and Cancer. 2022; 69:e29679..
Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia. Science Translational Medicine. 2022; 14:eabb7695..
2022; 94:s47-s48.. O086 FLASH Mechanisms Track (Oral Presentations) FLASH PROTON PENCIL BEAM SCANNING IRRADIATION USING A CLINICAL GANTRY DIMINISHES RADIATION INDUCED SKIN AND SOFT TISSUE TOXICITY IN MICE. Physica Medica: an international journal devoted to the applications of physics to medicine and biology.
2022; 2022.01.31.478534.. PDX models of relapsed pediatric AML preserve global gene expression patterns and reveal therapeutic targets.
The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia. Leukemia. 2022; 36:438-451..
2021; 111:e172.. Patterns of Anesthesia Use in a Large Multi-Institution Pediatric Cohort: A Report of the Pediatric Proton/Photon Consortium Registry (PPCR) Study. International Journal of Radiation: Oncology - Biology - Physics.
Can Rational Combination of Ultra-high Dose Rate FLASH Radiotherapy with Immunotherapy Provide a Novel Approach to Cancer Treatment?. Comparative Haematology International. 2021; 33:713-722..
2021; 111:s85-s86.. Focal vs. Craniospinal Irradiation in Multi-Modality Therapy for Atypical Teratoid/Rhabdoid Tumor (ATRT): Results From the Pediatric Proton/Photon Consortium Registry. International Journal of Radiation: Oncology - Biology - Physics.
In Regard to Buchsbaum et al. International Journal of Radiation: Oncology - Biology - Physics. 2021; 110:1544-1545..
Treatment of posttransplant lymphoproliferative disorder with poor prognostic features in children and young adults: Short-course EPOCH regimens are safe and effective. Pediatric Blood and Cancer. 2021; 68:e29126..
2021; 39:e15012.. Deep learning to identify and predict cardiotoxicities of anticancer drugs. Journal of Clinical Oncology.
Use of CD19-directed CAR T-Cell Therapy in an Infant With Refractory Acute Lymphoblastic Leukemia. Journal of Pediatric Hematology/Oncology. 2021; 43:152-154..
PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia. Frontiers in Oncology. 2021; 11:642466..
Visual outcomes following everolimus targeted therapy for neurofibromatosis type 1-associated optic pathway gliomas in children. Pediatric Blood and Cancer. 2021; 68:e28833..
2021; 5:100.. 81030 Utilizing a synergistic drug combination to target relapsed/refractory FLT3 mutant AML. Journal of Clinical and Translational Science.
A POETIC Phase II study of continuous oral everolimus in recurrent, radiographically progressive pediatric low-grade glioma. Pediatric Blood and Cancer. 2021; 68:e28787..
Differential transcriptome response to proton versus X-ray radiation reveals novel candidate targets for combinatorial PT therapy in lymphoma. Radiotherapy and Oncology. 2021; 155:293-303..
2020; 108:e233.. The Evolution of Proton Brainstem Constraints: A Multi-Institutional Study from the Pediatric Proton/Photon Consortium Registry (PPCR). International Journal of Radiation: Oncology - Biology - Physics.
A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study. Neuro-Oncology. 2020; 22:1527-1535..
2020; 80:5412.. Abstract 5412: Xenograft based detection of rare leukemic clones in minimal residual disease negative diagnostic specimens from pediatric patients. Cancer Research.
2020; 38:e22502.. Methylation profiling of hypomethylating agent response and treatment failure in pediatric and young adult MDS/AML. Journal of Clinical Oncology.
2020; 204:163.15.. The Ikaros1, IKZF1 , risk locus for Acute Lymphoblastic Leukemia (ALL) at chromosome 7p12.2 regulates the expression of the FIGNL1 gene. Journal of immunology (Baltimore, Md. : 1950).
Targeting AML-associated FLT3 mutations with a type I kinase inhibitor. The Journal of Clinical Investigation. 2020; 130:2017-2023..
An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology. British Journal of Radiology. 2020; 93:20190673..
2020; 6:45-491.. Proceedings to the 58th Annual Conference of the Particle Therapy Cooperative Group (PTCOG58) 10–15 June 2019. International Journal of Particle Therapy.
The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors. Nature Communications. 2019; 10:46..
Improved chemotherapy modeling with RAG-based immune deficient mice. Editor, Thomas D. PloS one. 2019; 14:e0225532..
2019; 134:3934.. Overcoming Adaptive Therapy Resistance in AML By Targeting Immune Response Pathways. Blood.
2019; 134:3370.. Modeling Effective AML Therapies - Comparative Anti-Leukemic Synergy of BCL2 and MCL1 Inhibition Combined and with Chemotherapy. Blood.
2019; 134:3766.. Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement. Blood.
Overcoming adaptive therapy resistance in AML by targeting immune response pathways. Science Translational Medicine. 2019; 11:eaaw8828..
Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Bevacizumab (SARC016). Sarcoma. 2019; 2019:7656747..
Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy. International Journal of Particle Therapy. 2019; 5:40-48..