Susanne Wells, PhD, investigates 1) mechanisms of cancer susceptibility in human organoids, 2) anti-viral discovery using single-cell transcriptomics, and 3) molecular activities of the human DEK oncogene. The long-term goal is to understand gene-environment interactions and their effects on health and disease and to translate the results into prevention and therapy. Our favorite model systems are human epidermis and mucosa. Research approaches include iPSC culture and differentiation, tissue engineering, transcriptomic and metabolomic profiling, and genetic mouse models.
Visit the Wells Lab.