Oncology

Publications

Azhar, M; Kincaid, Z; Kesarwani, M; Menke, J; Schwieterman, J; Ansari, S; Reaves, A; Ahmed, A; Shehzad, R; Khan, A; et al. Rational polypharmacological targeting of FLT3, JAK2, ABL, and ERK1 suppresses the adaptive resistance to FLT3 inhibitors in AML. Blood Advances. 2023; 7:1460-1476.

Bareja, R; Ismail, M; Martin, D; Nayate, A; Yadav, I; Labbad, M; Tamrazi, B; Salloum, R; Margol, A; Judkins, A; et al. MDB-44. A TRANSFER LEARNING APPROACH FOR AUTOMATIC SEGMENTATION OF TUMOR SUB-COMPARTMENTS AND TUMOR HABITAT IN PEDIATRIC MEDULLOBLASTOMA. Neuro-Oncology. 2023; 25:i71-i72.

Bareja, R; Ismail, M; Martin, D; Nayate, A; Yadav, I; Labbad, M; Tamrazi, B; Salloum, R; Margol, A; Judkins, A; et al. MDB-43. GRADIENT ENTROPY-BASED RADIOMIC RISK-SCORE FROM T1-WEIGHTED PRE-TREATMENT MRI SCANS CAN PREDICT SURVIVAL IN PEDIATRIC MEDULLOBLASTOMA. Neuro-Oncology. 2023; 25:i71.

Barron, T; Yalçin, B; Mochizuki, A; Cantor, E; Shamardani, K; Tlais, D; Franson, A; Lyons, S; Mehta, V; Jahan, SM; et al. CNSC-01. GABAERGIC NEURON-TO-GLIOMA SYNAPSES IN DIFFUSE MIDLINE GLIOMAS. Neuro-Oncology. 2023; 25:i11.

Bedard, MC; Chihanga, T; Carlile, A; Jackson, R; Brusadelli, MG; Lee, D; VonHandorf, A; Rochman, M; Dexheimer, PJ; Chalmers, J; et al. Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer. Nature Communications. 2023; 14:1975.

Bender, J; Damodharan, S; Moskop, A; Toner, K; Vatsayan, A; Capitini, C; Baggott, C; Schiff, DE; Katsanis, E; Raikar, SS; et al. Real-world use of tisagenlecleucel in children and young adults with relapsed or refractory B-cell lymphomas. Journal of Clinical Oncology. 2023; 41:10031.

Bender, JD; Oquendo-del Toro, H; Benoit, J; Howell, JC; Badia, P; Davies, SM; Grimley, MS; Jodele, S; Phillips, C; Burns, K; et al. Reduced-Intensity Conditioning Mitigates Risk for Primary Ovarian Insufficiency but Does Not Decrease Risk for Infertility in Pediatric and Young Adult Survivors of Hematopoietic Stem Cell Transplantation. Transplantation and cellular therapy. 2023; 29:130.e1-130.e8.

Bender, JD; Rubinstein, JD; Mizukawa, B; Perentesis, JP; Pommert, L. Use of gemcitabine, oxaliplatin, and anti-CD20 therapy in children and adolescents with non-Hodgkin lymphoma unfit for intensive therapy. Pediatric Blood and Cancer. 2023; 70:e30214.

Brivio, E; Pennesi, E; Willemse, M; Jiang, Y; van der Velden, V; Beverloo, B; Hudson, C; Kuttschreuter, L; van der Sluis, I; Brethon, B; et al. P676: UPDATED RESULTS FROM THE TRIAL ITCC-054/COG-AAML1921: BOSUTINIB IN NEWLY DIAGNOSED AND RESISTANT/INTOLERANT PEDIATRIC PATIENTS WITH CHRONIC MYELOID LEUKEMIA. HemaSphere. 2023; 7:e506783a.

Burke, GA A; Vinti, L; Kabickova, E; Beishuizen, A; Tacyildiz, N; Uyttebroeck, A; Kang, HJ; Luisi, F; Minard-Colin, V; Burkhardt, B; et al. Ibrutinib plus RICE or RVICI for relapsed/refractory mature B-cell non-Hodgkin lymphoma in children and young adults: SPARKLE trial. Blood Advances. 2023; 7:602-610.

Cooke-Barber, J; Brungardt, JG; Sorger, M; Pressey, JG; Turpin, B; Nagarajan, R; Szabo, S; Sorger, J; Johnson, N; Dasgupta, R. ASO Author Reflections: Minimizing Time in Hospital via Bone Biopsy or Other Means. Annals of Surgical Oncology. 2023; 30:3666.

Cooke-Barber, J; Brungardt, JG; Sorger, M; Pressey, JG; Turpin, B; Nagarajan, R; Szabo, S; Sorger, J; Johnson, N; Dasgupta, R. ASO Visual Abstract: Pediatric and Young Adult Image-Guided Percutaneous Bone Biopsy-A New Standard of Care?. Annals of Surgical Oncology. 2023; 30:3667.

Cooke-Barber, J; Brungardt, JG; Sorger, M; Pressey, JG; Turpin, B; Nagarajan, R; Szabo, S; Sorger, J; Johnson, N; Dasgupta, R. Pediatric and Young Adult Image-Guided Percutaneous Bone Biopsy-A New Standard of Care?. Annals of Surgical Oncology. 2023; 30:3658-3665.

D’Alessandro, PR. Research-Based Theater in the Pediatric Oncology Setting: Balancing Ethical Tensions. Qualitative Inquiry. 2023; 29:305-313.

Dandamudi, A; Seibel, W; Tourdot, B; Cancelas, JA; Akbar, H; Zheng, Y. Structure-Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents. International Journal of Molecular Sciences. 2023; 24:4167.

Daugherty, EC; Mascia, A; Zhang, Y; Lee, E; Xiao, Z; Sertorio, M; Woo, J; McCann, C; Russell, K; Levine, L; et al. FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases (FAST-01): Protocol for the First Prospective Feasibility Study. JMIR Research Protocols. 2023; 12:e41812.

de Blank, P; Nishiyama, A; López-Juárez, A. A new era for myelin research in Neurofibromatosis type 1. Glia. 2023; 71:2701-2719.

Forlenza, CJ; Rosenzweig, J; Mauguen, A; Buhtoiarov, I; Cuglievan, B; Dave, H; Deyell, RJ; Flerlage, JE; Franklin, AK; Krajewski, J; et al. Brentuximab vedotin after autologous transplantation in pediatric patients with relapsed/refractory Hodgkin lymphoma. Blood Advances. 2023; 7:3225-3231.

Galletta, TJ; Lane, A; Lutzko, C; Leemhuis, T; Cancelas, JA; Khoury, R; Wang, YZ M; Hanley, PJ; Keller, MD; Bollard, CM; et al. Third-Party and Patient-Specific Donor-Derived Virus-Specific T Cells Demonstrate Similar Efficacy and Safety for Management of Viral Infections after Hematopoietic Stem Cell Transplantation in Children and Young Adults. Transplantation and cellular therapy. 2023; 29:305-310.

Galletta, TJ; Rubinstein, JD; Krupski, C; Nelson, AS; Khoury, R; Dandoy, CE; Davies, SM; Phillips, CL. Durable remissions achieved with reinfusion of CD19-directed CAR-T despite failure to induce or maintain B-cell aplasia and single-center experience with reinfusion of tisagenlecleucel. Pediatric Blood and Cancer. 2023; 70:e30271.

Garrett, MC; Albano, R; Carnwath, T; Elahi, L; Behrmann, CA; Pemberton, M; Woo, D; O’Brien, E; VanCauwenbergh, B; Perentesis, J; et al. HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma. Scientific Reports. 2023; 13:12433.

Gossai, N; Bhojwani, D; Schafer, ES; Chang, BH; Pommert, L; Verma, A; Malvar, J; Chi, YY; Hitzler, J; Burke, MJ; et al. Patients with Down syndrome can be included in early phase clinical trials- a report from the T2016-003 Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) study. Leukemia. 2023; 37:1138-1140.

Gounder, M; Ratan, R; Alcindor, T; Schöffski, P; Van Der Graaf, WT; Wilky, BA; Riedel, RF; Lim, A; Smith, LM; Moody, S; et al. Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors. The New England journal of medicine. 2023; 388:898-912.

Heczey, A; Xu, X; Courtney, AN; Tian, G; Barragan, GA; Guo, L; Amador, CM; Ghatwai, N; Rathi, P; Wood, MS; et al. Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results. Nature Medicine. 2023; 29:1379-1388.

Hunt, BG; Davis, JC; Fox, LH; Vicente-Muñoz, S; Lester, C; Wells, SI; Waltz, SE. RON-augmented cholesterol biosynthesis in breast cancer metastatic progression and recurrence. Oncogene: Including Oncogene Reviews. 2023; 42:1716-1727.

Ismail, M; Craig, S; Ahmed, R; de Blank, P; Tiwari, P. Opportunities and Advances in Radiomics and Radiogenomics for Pediatric Medulloblastoma Tumors. Diagnostics. 2023; 13:2727.

Johnston, ME; Farooqui, ZA; Nagarajan, R; Pressey, JG; Turpin, B; Dasgupta, R. Fluorescent-guided surgery and the use of indocyanine green sentinel lymph node mapping in the pediatric and young adult oncology population. Cancer. 2023; 129:3962-3970.

Kleman, A; Singavi, A; Pommert, L; Mathison, AJ; Hari, P; Dhakal, B; Mohan, M; Janz, S; Knight, JM; Shah, MV; et al. A timeline of genetic variant enrichment: from multiple myeloma diagnosis to myeloma-associated myeloid malignancy. Blood Advances. 2023; 7:5549-5553.

Lazow, M; Baxter, P; Stanek, J; Rodriguez, D; Kumar, SS; Palmer, J; Leach, J; Mikael, L; Thomas, D; Fuller, C; et al. DIPG-54. UPDATED FINDINGS FROM THE PHASE IB STUDY OF UNESBULIN (PTC596) IN CHILDREN WITH NEWLY-DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG): A REPORT FROM THE COLLABORATIVE NETWORK FOR NEURO-ONCOLOGY CLINICAL TRIALS (CONNECT). Neuro-Oncology. 2023; 25:i25-i26.

Lazow, M; Palmer, J; Stanek, J; Baxter, P; Thomas, D; Salloum, R; de Blank, P; Mikael, L; Kumar, SS; Leonard, J; et al. DIPG-52. EXTRAPONTINE PROGRESSION WITH STABLE PONTINE DISEASE POST-RADIOTHERAPY IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) ON A CONNECT TRIAL: IMPLICATIONS FOR RADIATION TREATMENT VOLUMES. Neuro-Oncology. 2023; 25:i25.

Lazow, MA; Salloum, R; Pressey, JG. Comorbidity Burden in a Cohort of Adolescent and Young Adult Patients Diagnosed with Central Nervous System Tumors and Sarcomas. Journal of Adolescent and Young Adult Oncology. 2023; 12:215-223.

Lerman, BJ; Li, Y; Carlowicz, C; Granger, M; Cash, T; Sadanand, A; Somers, K; Ranavaya, A; Weiss, BD; Choe, M; et al. Progression-Free Survival and Patterns of Response in Patients With Relapsed High-Risk Neuroblastoma Treated With Irinotecan/Temozolomide/Dinutuximab/Granulocyte-Macrophage Colony-Stimulating Factor. Journal of Clinical Oncology. 2023; 41:508-516.

Liu, X; Sato, N; Yabushita, T; Li, J; Jia, Y; Tamura, M; Asada, S; Fujino, T; Fukushima, T; Yonezawa, T; et al. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia. EMBO Molecular Medicine. 2023; 15:e15631.

Marion, W; Koppe, T; Chen, CC; Wang, D; Frenis, K; Fierstein, S; Sensharma, P; Aumais, O; Peters, M; Ruiz-Torres, S; et al. RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia. Leukemia. 2023; 37:1698-1708.

Mascia, AE; Daugherty, EC; Zhang, Y; Lee, E; Xiao, Z; Sertorio, M; Woo, J; Backus, LR; McDonald, JM; McCann, C; et al. Proton FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases: The FAST-01 Nonrandomized Trial. JAMA oncology. 2023; 9:62-69.

McGrady, ME; Ketterl, TG; Norris, RE; Perentesis, JP; Pettee, D; Mara, CA; Breen, G; Pai, AL H. Barriers to medication adherence among adolescents and young adults with cancer. Pediatric Blood and Cancer. 2023; 70:e30186.

McNerney, KO; Lim, SS; Miller, A; Amankwah, E; Dreyzin, A; Vatsayan, A; Hermiston, M; Baggott, C; Prabhu, S; Pacenta, HL; et al. 262 High Disease Burden and Severe Neutropenia Predict HLH Toxicity in Patients with B-Acute Lymphoblastic Leukemia (B-ALL) Treated with Tisagenlecleucel in the PRWCC. Transplantation and cellular therapy. 2023; 29:s202-s203.

Merjaneh, N; Kim, H; Escoto, H; Metts, J; Ray, A; Bukowinski, A; Leblanc, Z; Fair, D; Watanbe, M; Alva, E; et al. Strategies for the Treatment of Infantile Soft Tissue Sarcomas With BCOR Alterations. Journal of Pediatric Hematology/Oncology. 2023; 45:315-321.

Minneci, PC; Bergus, KC; Lutz, C; Aldrink, J; Bence, C; Breech, L; Dillon, PA; Downard, C; Ehrlich, PF; Fallat, M; et al. Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients. Journal of the American Medical Association. 2023; 330:1247-1254.

Mochizuki, A; Partap, S. Pediatric Embryonal Tumors. In: Mrugala MM; Gatson NTN; Kurz SC; Nevel KS; Clarke JL, Ed. Neuro-Oncology Compendium for the Boards and Clinical Practice. : Oxford University Press (OUP); Oxford University Press (OUP); 2023.

Morrison, A; Pressey, J; Roth, LP; Tulchinskaya, V; Strieich-TIlles, T. 34. Atypical Presentation of Granulosa Cell Tumor in an Adolescent: A Case Report. Journal of Pediatric and Adolescent Gynecology. 2023; 36:187.

Morrison, A; Pressey, JG; VandenHeuvel, K; Streich-Tilles, T. Atypical Presentation of Granulosa Cell Tumor in an Adolescent: A Case Report. Journal of Pediatric and Adolescent Gynecology. 2023; 36:553-555.

Moscato, EL; Fisher, AP; Pillay-Smiley, N; Salloum, R; Wade, SL. Caregivers matter: Neurological vulnerability for pediatric brain tumor survivors. 2023; 10:418-428.

Na, B; Wang, AC; Watterson, CT; Martinez-Agosto, J; Saitta, S; Dutra-Clarke, M; Bhansali, F; Pineles, SL; Chang, VY; Shah, VS; et al. An unusual presentation of bilateral optic pathway glioma in Crouzon Syndrome. Pediatric Hematology-Oncology (Informa). 2023; 40:800-806.

Nguyen, HT; Tang, W; Webster, AL H; Whiteaker, JR; Chandler, CM; Errazquin, R; Roohollahi, K; Fritzke, M; Hoskins, EE; Jonlin, E; et al. Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource. International Journal of Cancer. 2023; 153:183-196.

O'Brien, MM; McNeer, JL; Rheingold, SR; Devidas, M; Chen, Z; Bhojwani, D; Ramsey, LB; Agrawal, A; Wood, BL; Suh, E; et al. A phase 3 trial of inotuzumab ozogamicin for high-risk B-ALL: Second safety phase results from Children’s Oncology Group AALL1732. Journal of Clinical Oncology. 2023; 41:10016.

Phillips, CL; Krupski, C; Khoury, R; Dandoy, CE; Nelson, AS; Galletta, TJ; Faulhaber, A; Davies, SM; Rubinstein, JD. Post CAR T-cell therapy outcomes and management in HSCT-naive patients: a single-center experience. 2023; 2:1151744.

Pillay-Smiley, N; Fletcher, JS; de Blank, P; Ratner, N. Shedding New Light: Novel Therapies for Common Disorders in Children with Neurofibromatosis Type I. Pediatric Clinics of North America. 2023; 70:937-950.

Pillay-Smiley, N; Leach, J; Lane, A; Hummel, T; Fangusaro, J; de Blank, P. Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B. Cancers. 2023; 15:2109.

Raetz, EA; Teachey, DT; Minard, C; Liu, X; Norris, RE; Denic, KZ; Reid, J; Evensen, NA; Gore, L; Fox, E; et al. Palbociclib in combination with chemotherapy in pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia and lymphoma: A Children's Oncology Group study (AINV18P1). Pediatric Blood and Cancer. 2023; 70:e30609.

Reed, HD; Do, H; Weller, E; Farrar, JE; Gamper, C; Lau, BW; Pommert, L; Atkinson, I; Joos, M; Loveless, S; et al. Lymphoid Malignancies in Shwachman-Diamond Syndrome: Incidence, Clinical Features, and Outcomes from the North American SDS Registry. Blood. 2023; 142:5662.

Roehrig, A; Indelicato, DJ; Paulino, AC; Ermoian, R; Hartsell, W; Perentesis, J; Hill-Kayser, C; Lee, JY; Laack, NN; Mangona, V; et al. Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR). Journal of Neuro-Oncology. 2023; 162:353-362.

Rubinstein, JD; Breese, EH; Krupski, MC; O'Brien, MM; Dandoy, CE; Mizukawa, B; Khoury, R; Norris, RE; Davies, SM; Phillips, CL. The Choice of Either Conventional Chemotherapy or Inotuzumab Ozogamicin as Bridging Regimen Does Not Appear To Impact Clinical Response to CD19-Directed CAR-T Therapy in Pediatric B-ALL. Transplantation and cellular therapy. 2023; 29:311.e1-311.e7.

Salloum, R; Huang, J; Stewart, CF; Fuller, C; Smolarek, T; Lenzen, A; Waanders, AJ; Baxter, P; Lindsay, H; Robison, N; et al. TRLS-11. A PHASE 1 STUDY OF SAVOLITINIB IN RECURRENT, PROGRESSIVE, OR REFRACTORY MEDULLOBLASTOMA, HIGH-GRADE GLIOMA, DIFFUSE INTRINSIC PONTINE GLIOMA, AND CENTRAL NERVOUS SYSTEM (CNS) TUMORS HARBORING MET ABERRATIONS: A PEDIATRIC BRAIN TUMOR CONSORTIUM TRIAL. Neuro-Oncology. 2023; 25:i81.

Shukla, S; Saha, T; Rama, N; Acharya, A; Le, T; Bian, F; Donovan, J; Tan, LA; Vatner, R; Kalinichenko, V; et al. Ultra-high dose-rate proton FLASH improves tumor control. Radiotherapy and Oncology. 2023; 186:109741.

Sirhan, Z; Sells, BE; Fleming, J; Manring, HR; Graham, RT; McElroy, JP; Haque, SJ; Boué, DR; Becker, AP; Bell, EH; et al. BIOL-05. IDENTIFICATION AND VALIDATION OF PA2G4 AS A POTENTIAL THERAPEUTIC TARGET IN PEDIATRIC DIFFUSE GLIOMAS. Neuro-Oncology. 2023; 25:i6.

Soni, UK; Wang, Y; Pandey, RN; Roberts, R; Pressey, JG; Hegde, RS. Molecularly Defined Subsets of Ewing Sarcoma Tumors Differ in Their Responses to IGF1R and WEE1 Inhibition. Clinical Cancer Research. 2023; 29:458-471.

Taylor, ZL; Miller, TP; Poweleit, EA; DeGroote, NP; Pommert, L; Awoniyi, O; Board, SG; Ugboh, N; Joshi, V; Ambrosino, N; et al. Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org. Clinical and Translational Science. 2023; 16:2130-2143.

Teoh, Z; Danziger-Isakov, L; Courter, JD; Frenck, RW; Grimley, MS; Marsh, RA; Paulsen, GC; Phillips, CL; Spearman, P; Chima, RS; et al. Tocilizumab for Treatment of Children and Young Adults With Severe Acute COVID-19: Experience at a Quaternary-care Children's Hospital. The Pediatric Infectious Disease Journal. 2023; 42:119-121.

Trout, AT; Norris, RE; de Blank, PM K; Backus, LR; Towbin, AJ; Nash, JM. Clinical trials: A plea to cooperative groups, consortia, pharmaceutical companies, and lead investigators for reasonable imaging protocols. Pediatric Blood and Cancer. 2023; 70:e30362.

Wilcher, KE; Page, ER H; Privette Vinnedge, LM. The impact of the chromatin binding DEK protein in hematopoiesis and acute myeloid leukemia. Experimental Hematology. 2023; 123:18-27.

Williams, M; Sugimoto, C; Regan, S; Pitzer, E; Fritz, A; Sertorio, M; Mascia, A; Vatner, R; Perentesis, J; Vorhees, C. Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model. Neurotoxicology and Teratology. 2023; 98:107276.

Wyatt, KD; Noyd, DH; Wood, NM; Phillips, CA; Miller, TP; Rubin, EM; Winestone, LE; Waanders, AJ; Perentesis, JP; Aplenc, R. Data standards in pediatric oncology: Past, present, and future. Pediatric Blood and Cancer. 2023; 70:e30128.