Oncology

Publications

Almohtasib, J; Indelicato, DJ; Paulino, AC; Mihalcik, S; Lee, J; Ermoian, R; Chang, JH C; Kwok, Y; Perentesis, J; Perkins, SM; Hill-Kayser, C; Zeina, W; Laack, NN; Yock, TI; Gargollo, PC. Assessing Acute and Long-Term Toxicities of Proton Radiation Therapy in Pediatric Pelvic Tumors: Findings From the Pediatric Proton Consortium Registry. Pediatric Blood and Cancer. 2025; e31811.

Armstrong, AE; Daw, NC; Renfro, LA; Geller, JI; Kalapurakal, JA; Khanna, G; Paulino, AC; Perlman, EJ; Ehrlich, PF; Gow, KW; Warwick, AB; Grundy, PE; Fernandez, CV; Mullen, EA; Dome, JS. Treatment of focal anaplastic Wilms tumor: A report from the Children's Oncology Group AREN0321 and AREN03B2 studies. Cancer. 2025; 131:e35713.

Bacha, J; Brown, D; Geller, J; Oesterheld, J; Thompson, P; Kim, A; McManus, M; Kanekal, S; Leggas, M; Lopez, L; Sankar, N; Yam, N; Wagner, L. Abstract LB266: A multicenter phase 1-2a clinical study of Orotecan® (oral irinotecan HCl, VAL-413) in patients with recurrent pediatric solid tumors. Cancer Research. 2025; 85:lb266.

Bauchat, A; Peterson, A; Ahn, KW; Mehta, PA; Phillips, CL; Schultz, KR; Sharma, A; Broglie, L; Qayed, M. Impact of Graft Versus Host Disease Following Allogeneic Hematopoietic Cell Transplantation on Leukemia Free Survival in Hematologic Malignancies: A CIBMTR Analysis. Transplantation and Cellular Therapy. 2025; 31:s60-s61.

Bedard, MC; Rivera-Cruz, CM; Chihanga, T; VonHandorf, A; Tang, AL; Zender, C; Weirauch, MT; Ferris, R; Wise-Draper, TM; Adam, M; Wells, SI. A Single-Cell Transcriptome Atlas of Epithelial Subpopulations in HPV-Positive and HPV-Negative Head and Neck Cancers. Viruses-Basel. 2025; 17:461.

Bender, J; Davies, SM; Myers, KC; Benoit, SW. Beyond Survival: Assessing Renal and Cardiovascular Health in Fanconi Anemia Adolescents and Young Adults Post-Stem Cell Transplant. Transplantation and Cellular Therapy. 2025; 31:s375-s376.

Boldt, A; Bender, J; Jodele, S; Davies, SM; Benoit, SW. Differential Filtration of Macromolecules: A Novel Indicator of Mortality Risk in Pediatric HSCT Patients. Transplantation and Cellular Therapy. 2025; 31:s145-s146.

Brown, A; Pommert, L. GATA Lot to Learn: Decoding the Drivers of Down Syndrome-Associated Acute Leukemias. 2025; 22.

Childress, A; Koch, A; Vallee, E; Steller, A; Raskin, S. The Current Landscape of Molecular Pathology for the Diagnosis and Treatment of Atypical Teratoid Rhabdoid Tumor. Journal of Molecular Pathology. 2025; 6:13.

D’Alessandro, PR; Homanick, CE; Cooper, BD; Ferguson, K; Rutan, H; Pressey, JG. "From Drowning to Treading Water ": Adolescents and Young Adults Living with Incurable and Indolent Metastatic Soft Tissue Sarcoma for More than Two Years. Cancers. 2025; 17:442.

Davis, K; Molloy, E; Marks, K; Breese, E; Michael Taylor, J; Broomall, E; Stalets, E. 667: SEVERE METHOTREXATE-INDUCED NEUROTOXICITY IN A HISPANIC ADOLESCENT GIRL WITH B-ALL. Critical Care Medicine. 2025; 53.

Dela Cruz, FS; Fox, E; DuBois, SG; Friedman, GK; Croop, JM; Kim, AR; Morgenstern, DA; Balis, FM; Macy, ME; Pressey, JG; He, CS; Aluri, J; Okpara, CE; Glade Bender, JL. A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric and Young Adult Solid Tumors. Pediatric Blood and Cancer. 2025; 72:e31692.

Dombi, E; Gross, AM; Widemann, BC; Weiss, BD; Plotkin, SR; Ahlawat, S. Challenges in Assessing Response in Clinical Trials for Neurofibromatosis Type 1 Plexiform Neurofibromas. Journal of Clinical Oncology. 2025; 43:1843-1844.

Eigenbrood, J; Wong, N; Mallory, P; Pereira, JS; Williams, D; Morris, DW; Beck, JA; Cronk, JC; Sayers, CM; Mendez, M; LeBlanc, AK; Cotter, J; Kaplan, RN; McEachron, TA. Spatial Profiling Identifies Regionally Distinct Microenvironments and Targetable Immunosuppressive Mechanisms in Pediatric Osteosarcoma Pulmonary Metastases. Cancer Research. 2025; 85:2320-2337.

Fathi Kazerooni, A; Khalili, N; Liu, X; Haldar, D; Jiang, Z; Zapaishchykova, A; Pavaine, J; Shah, LM; Jones, BV; Sheth, N; Resnick, A; Bakas, S; Vossough, A; Linguraru, MG. BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023. 2025; 3:72-87.

Fernandez, K; Hoetink, A; Konrad-Martin, D; Berndtson, D; Clark, K; Dreisbach, L; Geller, JI; Goffi-Gomez, MV; Grosnik, A; Jamis, C; Sanchez, VA; Van Den Heuvel-Eibrink, MM; Brewer, CC; Poling, GL. Roadmap to a Global Template for Implementation of Ototoxicity Management for Cancer Treatment. Ear and Hearing. 2025; 46:286-297.

Fleifil, Y; Gulati, R; Jennings, K; Miethke, A; Bondoc, A; Tiao, G; Geller, JI; Karns, R; Timchenko, L; Timchenko, N. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers. 2025; 17:83.

Freyer, DR; Ohlsen, TJ D; Don, D; Orgel, E; Hayashi, RJ; Lieu, JE; Foster, JH; Sitton, MS; Geller, JI; Choo, DI; Grunstein, E; O'Neill, AF; Rahbar, R; Anderson, JJ. Feasibility and Safety of Intratympanic Administration of Sustained-Exposure Dexamethasone Thermosensitive Gel (OTO-104) for Prevention of Cisplatin-Induced Hearing Loss in Children: A Multisite Phase 2 Randomized Clinical Trial. Pediatric Blood and Cancer. 2025; 72:e31680.

Galletta, TJ; Benoit, SW; Markham, J; Pillay-Smiley, N; Queen, K; Graham, RT. Elevated Bromide Levels Due to Tazemetostat Therapy Treated With Salt and Water Supplementation in Two Children With Atypical Teratoid Rhabdoid Tumor. Pediatric Blood and Cancer. 2025; 72:e31803.

Garrett, MC; Carnwath, T; Albano, R; Zhuang, Y; Behrmann, CA; Pemberton, M; Barakat, F; Lober, R; Hoeprich, M; Paravati, A; Perentesis, J; Nasser, R; Medvedovic, M; Plas, DR. CPI203, a BET inhibitor, down-regulates a consistent set of DNA synthesis genes across a wide array of glioblastoma lines. Editor, Li M. PloS one. 2025; 20:e0306846.

Geller, JI; Renfro, LA; Grundy, PE; Perlman, EJ; Kalapurakal, JA; Ehrlich, PF; Biegel, J; Huff, V; Warwick, AB; Paulino, A; Ward, DA; Anderson, JR; Fernandez, CV; Dome, JS. Rhabdoid Tumor of the Kidney and Soft Tissues: Results from National Wilms Tumor Study-5 and Children's Oncology Group Study AREN0321. Pediatric Blood and Cancer. 2025; 72:e31490.

Ghosh, A; Li, H; Towbin, A; Turpin, B; Trout, A. T2-weighted MRI radiomics for the prediction of pediatric and young adult rhabdomyosarcoma alveolar subtype and distant metastasis: a pilot study. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2025; 55:1149-1161.

Gilene, S; Haacker, L; Rutan, H; Pressey, JG. The Threat of Medical Misinformation: A Case of Ivermectin Toxicity in a Pediatric Oncology Patient. Pediatric Blood and Cancer. 2025; 72:e31876.

Gilene, S; Knapke, S; Leino, D; Roy, S; Raskin, S. A novel POT1-TPD presentation: A germline pathogenic POT1 variant discovered in a patient with newly diagnosed posterior fossa ependymoma. Cancer genetics. 2025; 292-293:38-43.

Gopu-Gilboy, A; Sheak, JR; Monangi, N; Damianos, A; Pommert, L. Shining a TORCH on a Case of Blueberry Muffin Rash in a Newborn Infant. NeoReviews.org. 2025; 26:e191-e196.

Graff, Z; Pommert, L. DARA to Believe: Anti-CD38 Antibody Improves Outcomes in Relapsed/Refractory Pediatric T-Cell Lymphoblastic Leukemia and Lymphoma. 2025; 22.

Hall, AD; Hendricks, HA; Bowers, KA; Geller, JI; Bondoc, AJ; Tiao, GM; Taylor, AE; Otto, WR; Paulsen, GC; Danziger-Isakov, LA. Impact of Hepatoblastoma on Infectious Complications Following Pediatric Liver Transplantation. Pediatric Transplantation. 2025; 29:e70035.

Haney, M; Devine, KJ; Xavier, AC; Ford, JB; Audino, AN; Villagomez, L; Kebede, A; Rubinstein, JD. Posttransplant EBV-Positive Smooth Muscle Tumors in Children, Adolescents, and Young Adults: A Multi-Institution Experience. Pediatric Blood and Cancer. 2025; 72:e31678.

Hoyt, SB; Finocchio, CJ; Croll, E; Tawa, GJ; Zhang, M; Wang, J; Li, H; Ma, L; Li, K; Zhang, X; Culver-Cochran, AE; Rosenbaum, JS; Starczynowski, DT; Thomas, CJ. IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia. ACS Medicinal Chemistry Letters. 2025; 16:887-895.

Ismail, M; Um, H; Pineda, G; Salloum, R; Hollnagel, F; Ahmed, R; De Blank, P; Tiwari, P. Radiomic-based prognostic score for survival risk-stratification in pediatric medulloblastoma tumors: A multi-institutional study. Neuro-Oncology Advances. 2025; 7:vdaf107.

Johnstone, ME; Leck, AL; Lange, TE; Wilcher, KE; Shephard, MS; Paranjpe, A; Schutte, S; Wells, SI; Kappes, F; Salomonis, N; Privette Vinnedge, LM. DEK promotes mammary hyperplasia and is associated with H3K27me3 epigenetic modifications. Life Science Alliance. 2025; 8:e202503230.

Klages, KL; Gibson, CA; Barnett, KA; Schwartz, LE; Hicks, CA; Norris, RE; Kashikar-Zuck, S; Pai, AL H. Systematic Review of Pain Assessment Measures Used in Pediatric Acute Lymphoblastic Leukemia. Psycho-Oncology: journal of the psychological, social and behavioral dimensions of cancer. 2025; 34:e70063.

Koch, A; Childress, A; Vallee, E; Steller, A; Raskin, S. The Current Landscape of Molecular Pathology for the Diagnosis and Treatment of Pediatric Medulloblastoma. Journal of Molecular Pathology. 2025; 6:11.

Krisch, JM; Ermoian, RP; Indelicato, DJ; Lee, JY; Perentesis, JP; Perkins, SM; Laack, NN; Chang, JH; MacEwan, IJ; Wolden, SL; Wang, D; Yock, TI; Aridgides, PD. Outcomes following radiation therapy for embryonal tumor with multilayered rosettes (ETMR): results from the Pediatric Proton/Photon Consortium Registry (PPCR). Journal of Neuro-Oncology. 2025; 174:369-380.

Lafay-Cousin, L; Cansanay, D; Erker, C; Ratterman, E; Schlosser, MP; Nobre, L; Ronsley, R; Magimairajan, V; Pillay-Smiley, N; Cluster, A; Robinson, G; Dufour, D; Rutkowski, S; Bouffet, E. Medulloblastoma of early childhood. Salvage and outcome after initial CSI sparing approaches. 2025.

Lamoureux, AA; Fisher, MJ; Lemelle, L; Pfaff, E; Amir-Yazdani, P; Kramm, C; De Wilde, B; Kazanowska, B; Hutter, C; Pfister, SM; Jones, C; Doz, F; Laetsch, TW; Perreault, S. Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions. Clinical Cancer Research. 2025; 31:561-572.

Lichtenstein, DA; Sridharan, A; Khoury, R; Grimley, MS; Rubinstein, JD; Lutzko, CM; Wang, YM. Effect of Clinically Relevant Immunosuppressants on Viral Specific T-Cell (VST) in Vitro Function. Transplantation and Cellular Therapy. 2025; 31:s509-s510.

McGrady, ME; Webster, RT; Burke, M; Gomez, C; Breen, G; Herriott, JK; Norris, RE; Ketterl, TG. Developing Behavior Change Model-Informed and Participant-Engaged Retention Strategies for Adolescents and Young Adults With Cancer Enrolled on Behavioral and/or Psychosocial Trials. Pediatric Blood and Cancer. 2025; 72:e31583.

Mehta, PA; Nelson, A; Loveless, S; Lane, A; Fukuda, T; Teusink-Cross, A; Elder, D; Lagory, D; Miller, E; Cancelas, JA; Edwards, S; Chihanga, T; Wells, SI; Davies, SM. Phase 1 study of quercetin, a natural antioxidant for children and young adults with Fanconi anemia. Blood Advances. 2025; 9:1927-1939.

Moscato, EL; Fisher, AP; Patronick, J; Pillay-Smiley, N; Gerhardt, CA; Salloum, R; Wade, SL. Quality of Life for Rural and Appalachian Pediatric Brain Tumor Survivors in Ohio and Kentucky. Clinical Practice in Pediatric Psychology. 2025; 13:11-16.

Nguyen, P; Indelicato, DJ; Esterman, A; Paulino, AC; Ermoian, RP; Laack, NN; Perkins, SM; Mangona, V; Mihalcik, S; Lee, J; Perentesis, JP; MacEwan, I; Le, H; Yock, TI. Acute Toxicities of Proton Craniospinal Irradiation in Pediatric Medulloblastoma: A Pediatric Proton/Photon Consortium Registry (PPCR) Study. International Journal of Particle Therapy. 2025; 16:100747.

Papini, C; Mirzaei, S; Xing, M; Tonning Olsson, I; Salloum, R; de Blank, PM K; Lange, KR; King, TZ; Srivastava, D; Leisenring, WM; Robison, LL; Armstrong, GT; Krull, KR; Brinkman, TM. Neurocognitive outcomes and functional independence in adult survivors of childhood medulloblastoma diagnosed over 3 decades. Neuro-Oncology. 2025; 27:254-266.

Perotti, D; O’Sullivan, MJ; Walz, AL; Davick, J; Al-Saadi, R; Benedetti, DJ; Brzezinski, J; Ciceri, S; Cost, NG; Dome, JS; Spreafico, F; Geller, JI; van den Heuvel-Eibrink, MM; Hong, AL. Hallmark discoveries in the biology of non-Wilms tumour childhood kidney cancers. Nature Reviews Urology. 2025; 22:526-543.

Pommert, L; Tasian, SK. ‘Blin’-ing Is Winning for Children With B-Cell Acute Lymphoblastic Leukemia. 2025; 22.

Pressey, JG; Toebbe, B; Chandler, M; Szabo, S; Pitt, S. 23P Pre-diagnostic imaging reveals rapid emergence and progression of small cell carcinoma of the ovary hypercalcemic type (SCCOHT): Implications for monitoring carriers of SMARCA4 germline pathogenic variants (GPVs). ESMO Open. 2025; 10:104332.

Pruitt, DW; Bolikal, P. Rehabilitation of the Pediatric Cancer Patient. In: Stubblefield M; O'Dell M, Ed. Cancer Rehabilitation. New York: Springer Publishing Company; 2025.

Raskin, S; de Blank, P; Billups, CA; Li, Y; Olson, JM; Leary, SE S. Isotretinoin has no effect on event-free survival across high-risk medulloblastoma molecular groups when added to maintenance: A secondary analysis of the Children's Oncology Group ACNS0332 data. Neuro-Oncology Advances. 2025; 7:vdaf054.

Reed, HD; Do, H; Weller, E; Harris, MH; Reilly, CR; Tsai, HK; Farrar, JE; Lau, BW; Pommert, L; Gamper, C; Cheng, L; Malsch, M; Myers, K; Shimamura, A. Lymphoid malignancies in patients with Shwachman-Diamond syndrome. Blood. 2025; 145:2528-2532.

Rouce, RH; Dolan, JG; Phillips, CL; Qayed, M; Pulsipher, MA; Vernau, LM; Galletta, TJ; Votaw, S; Caraballo, GL; Yang, H; Tesfaye, M; Lee, S; O'Sullivan, E; Grupp, SA. Kymriah Real-World Effectiveness and Functional Persistence in Acute Lymphoblastic Leukemia (ALL) (KareALL): A Retrospective Analysis of the Effect of Current Tisagenlecleucel (tisa-cel) Manufacturing in Pediatric and Young Adult Patients (pts) with ALL. Transplantation and Cellular Therapy. 2025; 31:s219.

Sarangdhar, M; Snyder, J; O'Brien, E; VanCauwenbergh, B; Basu, M; Pressey, J; Perentesis, J. Abstract 3155: High-throughput drug repositioning identifies dinaciclib as a potent osteosarcoma inhibitor. Cancer Research. 2025; 85:3155.

Schmid, I; O'Neill, AF; Watanabe, K; Aerts, I; Branchereau, S; Brock, PR; Dandapani, M; Fresneau, B; Geller, J; Hishiki, T; Zsiros, J; Hiyama, E; Malogolowkin, M; Ansari, M. Global consensus from the PHITT consortium surrounding an interim chemotherapy guidance for the treatment of children with hepatoblastoma, hepatocellular neoplasm – not otherwise specified (HCN-NOS), hepatocellular carcinoma and fibrolamellar carcinoma after trial closure. EJC Paediatric Oncology. 2025; 5:100235.

Streefkerk, N; Masroor, A; Geller, JI; van Grotel, M; Ansari, M; Bouffet, E; Bleyer, A; Fresnau, B; Sullivan, M; Huitema, AD R; Veal, GJ; Brock, PR; Meijer, AJ M; van den Heuvel-Eibrink, MM. Local application of sodium thiosulfate as an otoprotectant for cisplatin-exposed patients – A narrative literature review to explore the potential benefit for children with cancer. EJC Paediatric Oncology. 2025; 5:100211.

Sutton, KS; Walz, AL; Groenendijk, A; Murphy, AJ; Pater, L; Janssens, GO; Brzezinski, J; Mullen, EA; Spreafico, F; Godzinski, J; Ehrlich, PF; Furtwangler, R; Brok, J; Geller, J. Remaining Challenges in the Treatment of Relapsed Wilms Tumor: Children's Oncology Group and International Society of Paediatric Oncology Perspectives. Pediatric Blood and Cancer. 2025; 72:e31790.

Tracy, ET; Engwall, A; Brown, EG; Sun, RC; Walther, A; Beckhorn, CB; Lal, D; Rothstein, DH; Roach, J; Cost, N; Kotagal, M; Gow, K; Weil, B; Davidoff, A. Essential Knowledge and Skills for the Practice of Pediatric Surgical Oncology: A Modified Delphi Consensus Study by the APSA Cancer Committee. Annals of Surgical Oncology. 2025; 32:5752-5771.

Trobaugh-Lotrario, AD; O'Neill, AF; Belmonte, KA; Malogolowkin, MH; Tiao, GM; Geller, JI. Characteristics of patients with liver tumors deemed ineligible for enrollment on Children's Oncology Group trial AHEP1531: An opportunity to expand inclusion criteria and improve outcome. Pediatric Blood and Cancer. 2025; 72:e31389.

Vallee, E; Steller, A; Childress, A; Koch, A; Raskin, S. The Current Landscape of Molecular Pathology for the Diagnosis and Treatment of Pediatric High-Grade Glioma. Journal of Molecular Pathology. 2025; 6:17.

Wade, I; Witkowski, L; Ahmed, A; Rowlands, CF; Banerjee, S; Pressey, JG; McVeigh, TP; Tischkowitz, MD; Foulkes, WD; Turnbull, C. Using cancer phenotype sex-specificity to enable unbiased penetrance estimation of SMARCA4 pathogenic variants for small cell carcinoma of the ovary, hypercalcemic type (SCCOHT). Genetics in Medicine. 2025; 27:101287.

Zorn, K; Pommert, L. First Relapse, Second Chance: Determinants of Survival After First Relapse in Pediatric Acute Lymphoblastic Leukemia. 2025; 22.