2024; 26:0.
. NFS-24. TUMOR VOLUME IN NEWLY DIAGNOSED OPTIC PATHWAY GLIOMAS ASSOCIATED WITH NF1 (NF1-OPG): PRELIMINARY RESULTS FROM THE INTERNATIONAL MULTICENTER NF1-OPG NATURAL HISTORY STUDY. Neuro-Oncology.nnU-Net-based Segmentation of Tumor Subcompartments in Pediatric Medulloblastoma Using Multiparametric MRI: A Multi-institutional Study. Radiology: Artificial Intelligence. 2024; 6:e230115.
.Fanconi anemia neuroinflammatory syndrome: brain lesions and neurologic injury in Fanconi anemia. Blood Advances. 2024; 8:3027-3037.
.Real-world use of tisagenlecleucel in children and young adults with relapsed or refractory B-cell lymphomas. Blood Advances. 2024; 8:4164-4168.
.Cardiac Dysfunction in Children and Young Adults Treated With MEK Inhibitors: A Retrospective, Single-Center Study. JACC: CardioOncology. 2024; 6:794-796.
.14q22.3 duplication including OTX2 in a girl with medulloblastoma: A case report with literature review. American Journal of Medical Genetics, Part A. 2024; 194:e63604.
.Chemical genetic screens reveal defective lysosomal trafficking as synthetic lethal with NF1 loss. Journal of Cell Science. 2024; 137:jcs262343.
.2024; 26:0.
. QOL-06. RECURRENCE PATTERNS AND SURVEILLANCE IMAGING IN PEDIATRIC BRAIN TUMOR SURVIVORS. Neuro-Oncology.Recurrence Patterns and Surveillance Imaging in Pediatric Brain Tumor Survivors. Journal of Pediatric Hematology/Oncology. 2024; 46:e227-e232.
.2024; 26:0.
. MDB-45. THE PTBP2 SPLICING FACTOR IS ESSENTIAL IN GROUP 3/4 MEDULLOBLASTOMA. Neuro-Oncology.Time to therapy and safety of testicular tissue cryopreservation in children undergoing gonadotoxic treatment or hematopoietic stem cell transplant. Journal of Pediatric Urology. 2024; 20:747.e1-747.e7.
.2024; 26:0.
. MDB-09. WNT AND GROUP 4 MEDULLOBLASTOMAS OF EARLY CHILDHOOD TREATED WITH HIGH DOSE CHEMOTHERAPY AND CRANIOSPINAL IRRADIATION SPARING APPROACH. Neuro-Oncology.SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation. Cell Reports. 2024; 43:114536.
.Toxicity profile of high-dose methotrexate in young children with central nervous system tumors. Pediatric Blood and Cancer. 2024; 71:e31213.
.2024; 26:0.
. TRLS-09. CONNECT1903: A PILOT AND SURGICAL STUDY OF LAROTRECTINIB FOR TREATMENT OF CHILDREN WITH NEWLY DIAGNOSED HGG WITH NTRK FUSION (NCT04655404). Neuro-Oncology.Ruxolitinib Pharmacokinetics and Pharmacodynamics in Children with Acute and Chronic Graft-versus-Host Disease. Transplantation and Cellular Therapy. 2024; 30:528.e1-528.e12.
.Evolution of Proton Radiation Therapy Brainstem Constraints on the Pediatric Proton/Photon Consortium Registry. Practical Radiation Oncology. 2024; 14:e507-e514.
.Chemotherapy resistance in acute myeloid leukemia is mediated by A20 suppression of spontaneous necroptosis. Nature Communications. 2024; 15:9189.
.Body Image Concerns in Adolescent and Young Adult Oncology Patients within Six Months of Upfront Diagnosis. Journal of Adolescent and Young Adult Oncology. 2024; 13:792-798.
.FLASH radiotherapy for the treatment of symptomatic bone metastases in the thorax (FAST-02): protocol for a prospective study of a novel radiotherapy approach. Radiation Oncology. 2024; 19:34.
.Temporal changes in treatment and late mortality and morbidity in adult survivors of childhood glioma: a report from the Childhood Cancer Survivor Study. Nature Cancer. 2024; 5:590-600.
.A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas. Clinical Cancer Research. 2024; 30:2068-2077.
.2024; 12:100227.
. O114 / #164 DOSE TO ORGANS AT RISK IMPACTS HEALTH-RELATED QUALITY OF LIFE OUTCOMES FOR CHILDREN WITH BRAIN TUMORS. International Journal of Particle Therapy.2024; 84:5912.
. Abstract 5912: Rational design of a small-molecule inhibitor targeting the allosteric site of sos1 in oncogenic k-ras pancreatic cancer. Cancer Research.Pediatric spindle cell/sclerosing rhabdomyosarcoma with FUS-TFCP2 fusion: a case report and literature review. Translational Pediatrics. 2024; 13:178-191.
.2024; 26:0.
. LGG-05. REPORT ON PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC)-029B, A PROSPECTIVE PHASE 2 CLINICAL TRIAL OF SELUMETINIB IN TREATING YOUNG PATIENTS WITH RECURRENT/PROGRESSIVE LOW-GRADE GLIOMA: NEW RESULTS ON STRATA 2, 5, AND 6 WITH UPDATED LONG-TERM SURVIVAL OUTCOMES ON STRATA 1, 3, AND 4. Neuro-Oncology.2024; 35:10.1681/asn.20241j3dwf9j.
. Single-Center Case Series of Congenital Anomalies of the Kidney and Urinary Tract and Hepatoblastoma. Journal of the American Society of Nephrology : JASN.A core outcome domain set to assess cutaneous neurofibromas related to neurofibromatosis type 1 in clinical trials. British Journal of Dermatology. 2024; 190:216-225.
.2024; 26:0.
. NFS-21. DEMOGRAPHIC, CLINICAL AND IMAGING CHARACTERISTICS OF NEWLY DIAGNOSED OPTIC PATHWAY GLIOMAS ASSOCIATED WITH NF1: RESULTS FROM THE INTERNATIONAL MULTICENTER NF1-OPG NATURAL HISTORY STUDY. Neuro-Oncology.Histogram Analysis of Apparent Diffusion Coefficient Maps Provides Genotypic and Pretreatment Phenotypic Information in Pediatric and Young Adult Rhabdomyosarcoma. Academic Radiology. 2024; 31:2550-2561.
.EZH2 is a key component of hepatoblastoma tumor cell growth. Pediatric Blood and Cancer. 2024; 71:e30774.
.Virus-Specific T Cells for the Treatment of Systemic Infections Following Allogeneic Hematopoietic Cell and Solid Organ Transplantation. Journal of the Pediatric Infectious Diseases Society. 2024; 13:S49-S57.
.Inhibition of Histone Deacetylase Activity Increases Cisplatin Efficacy to Eliminate Metastatic Cells in Pediatric Liver Cancers. Cancers. 2024; 16:2300.
.Cellular origin and molecular mechanisms of lung metastases in patients with aggressive hepatoblastoma. Hepatology Communications. 2024; 8:e0369.
.Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia. ACS Medicinal Chemistry Letters. 2024; 15:1843-1851.
.2024; 26:0.
. MDB-42. RADIOMIC TEXTURAL AND MORPHOLOGICAL-BASED FEATURES TO RISK-STRATIFY PEDIATRIC MEDULLOBLASTOMA PATIENTS. Neuro-Oncology.2024; 26:0.
. MDB-40. DEFORMATION-HETEROGENEITY RADIOMIC MEASURES TO RISK-STRATIFY PEDIATRIC MEDULLOBLASTOMA PATIENTS: A PRELIMINARY ANALYSIS. Neuro-Oncology.A Radiomic Approach for Evaluating Intra-Subgroup Heterogeneity in SHH and Group 4 Pediatric Medulloblastoma: A Preliminary Multi-Institutional Study. Cancers. 2024; 16:2248.
.2024; 21.
. Vitamin A to Keep GVHD Away: Single Oral High-Dose Vitamin A Before Bone Marrow Transplant Reduces Graft-Versus-Host Disease in Pediatric and Young Adult Patients.Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant. American Journal of Transplantation. 2024; 24:1634-1643.
.2024; 120:e697.
. Outcomes Following Radiation Therapy (RT) for Embryonal Tumor with Multilayered Rosettes (ETMR): Results from the Pediatric Proton/Photon Consortium Registry (PPCR). International Journal of Radiation: Oncology - Biology - Physics.Low-grade glioma in children with neurofibromatosis type 1: surveillance, treatment indications, management, and future directions. Child's Nervous System. 2024; 40:3241-3250.
.2024; 26:0.
. NFS-08. CLINICAL AND MOLECULAR FEATURES OF HIGH-GRADE GLIOMA IN CHILDREN AND ADULTS WITH NEUROFIBROMATOSIS TYPE 1: A PRELIMINARY ANALYSIS. Neuro-Oncology.2024; 26:viii180.
. PATH-13. MOLECULAR AND BIOLOGY CORRELATIVE RESULTS FROM THE PHASE 1B TRIAL OF UNESBULIN (PTC596) WITH RADIOTHERAPY IN CHILDREN NEWLY-DIAGNOSED WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG): A REPORT FROM THE COLLABORATIVE NETWORK FOR NEURO-ONCOLOGY CLINICAL TRIALS (CONNECT). Neuro-Oncology.Clinical outcomes of hypomethylating agents and venetoclax in newly diagnosed unfit and relapsed/refractory paediatric, adolescent and young adult acute myeloid leukaemia patients. British Journal of Haematology. 2024; 205:1055-1066.
.A case of co-occurring acute myeloid leukemia and relapsed diffuse large B-cell lymphoma in a young adult with Shwachman-Diamond syndrome. Pediatric Blood and Cancer. 2024; 71:e31137.
.2024; 26:0.
. LGG-37. A PHASE III STUDY COMPARING TWO CARBOPLATIN CONTAINING REGIMENS FOR CHILDREN AND YOUNG ADULTS WITH PREVIOUSLY UNTREATED LOW-GRADE GLIOMA. Neuro-Oncology.Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration. Cell. 2024; 187:2465-2484.e22.
.Navigating the Critical Translational Questions for Implementing FLASH in the Clinic. Seminars in Radiation Oncology. 2024; 34:351-364.
.Race and Ethnic Group Enrollment and Outcomes for Wilms Tumor: Analysis of the Current Era Children's Oncology Group Study, AREN03B2. Journal of the American College of Surgeons. 2024; 238:733-749.
.Vorinostat, temozolomide or bevacizumab with irradiation and maintenance BEV/TMZ in pediatric high-grade glioma: A Children's Oncology Group Study. Neuro-Oncology Advances. 2024; 6:vdae035.
.Impact of Multiple Beams on the FLASH Effect in Soft Tissue and Skin in Mice. International Journal of Radiation: Oncology - Biology - Physics. 2024; 118:253-261.
.Characteristics and outcomes of children, adolescent, and young adult patients with myelodysplastic neoplasms: A single-center retrospective analysis. Leukemia Research: clinical and laboratory studies. 2024; 144:107563.
.Feasibility pilot trial of a tailored medication adherence-promotion intervention for adolescents and young adults with cancer: Study design and protocol. Contemporary Clinical Trials. 2024; 139:107483.
.Antiresorptive and anti-angiogenic drug therapy in the pediatric population with reference to medication-related osteonecrosis of the jaw. International Journal of Oral and Maxillofacial Surgery. 2024; 53:496-502.
.2024; 26:0.
. DIPG-17. DYSREGULATED PURINE METABOLISM IN A LETHAL CHILDHOOD BRAINSTEM TUMOR REVEALS NEW TREATMENT STRATEGIES WITH OLD DRUGS. Neuro-Oncology.2024; 26:0.
. IMMU-17. A PHASE I STUDY OF INTRATUMORAL/PERITUMORAL HERPES SIMPLEX VIRUS-1 MUTANT HSV1716 IN PATIENTS WITH REFRACTORY OF RECURRENT HIGH-GRADE GLIOMAS: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY. Neuro-Oncology.Germline PTCH1: c.361_362insAlu alteration identified by comprehensive exome and RNA sequencing in a patient with Gorlin syndrome. American Journal of Medical Genetics, Part A. 2024; 194:e63788.
.Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma: Guidelines established by the International Pediatric Low-Grade Glioma Coalition Clinical Trial Working Group. Neuro-Oncology. 2024; 26:407-416.
.Long-term outcomes and patterns of relapse in patients with bilateral Wilms tumor or bilaterally predisposed unilateral Wilms tumor, a report from the COG AREN0534 study. International Journal of Cancer. 2024; 155:1824-1831.
.Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3 K27M-mutant glioma. Neuro-Oncology. 2024; 26:S155-S164.
.Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition: A modified Delphi approach to build international consensus-based definitions-International Pediatric Low-Grade Glioma Coalition. Neuro-Oncology. 2024; 26:1357-1366.
.Evolving therapies, neurocognitive outcomes, and functional independence in adult survivors of childhood glioma. Journal of the National Cancer Institute. 2024; 116:288-298.
.2024; 21.
. Enhancing Risk Stratification for Pediatric B-Cell Acute Lymphoblastic Leukemia: No Longer a ‘PI’ in the Sky Idea?.2024; 26:0.
. MDB-86. ISOTRETINOIN HAS NO EFFECT ON EVENT FREE SURVIVAL ACROSS HIGH-RISK MEDULLOBLASTOMA MOLECULAR SUBGROUPS WHEN ADDED TO MAINTENANCE CHEMOTHERAPY: A SECONDARY ANALYSIS OF THE CHILDREN’S ONCOLOGY GROUP ACNS0332 DATA. Neuro-Oncology.Pediatric Oncology and Obesity: An Introduction for General Pediatricians. Clinical Pediatrics. 2024; 63:589-593.
.Bilateral Wilms tumor with anaplasia: A report from the Children's Oncology Group Study AREN0534. Pediatric Blood and Cancer. 2024; 71:e30981.
.Current practice of cancer predisposition testing in pediatric patients with CNS tumors in the United States. Pediatric Blood and Cancer. 2024; 71:e30725.
.2024; 21.
. Eculizumab: Inhibiting C5 Earns a High Five in Prospective Pediatric, Multicenter, High-risk Transplant-associated Thrombotic Microangiopathy Study.Optimizing early phase clinical trial washout periods: a report from the Therapeutic Advances in Childhood Leukemia and Lymphoma consortium. Journal of the National Cancer Institute. 2024; 116:1721-1729.
.2024; 42:11510.
. Prospective evaluation of pre-treatment ctDNA burden in localized osteosarcoma to identify patients with inferior outcomes: A report from the LEOPARD study. Journal of Clinical Oncology.2024; 21.
. Risk-stratified Treatment for Pediatric Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia.Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science Advances. 2024; 10:eadj3010.
.Lipid profiling of RON and DEK-dependent signaling in breast cancer guides discovery of gene networks predictive of poor outcomes. Frontiers in Oncology. 2024; 14:1382986.
.2024; 26:0.
. MDB-100. RETROSPECTIVE ANALYSIS OF CUMULATIVE DOSING OF CHEMOTHERAPY AGENTS AND THE EFFECT ON SURVIVAL IN PATIENTS WITH AVERAGE RISK MEDULLOBLASTOMA TREATED ON CHILDRENS ONCOLOGY GROUP STUDY ACNS0331. Neuro-Oncology.2024; 26:0.
. QOL-38. PSYCHOSOCIAL OUTCOMES OF CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG) –PROSPECTIVE, LONGITUDINAL PROMIS ASSESSMENTS OF PATIENTS ENROLLED ON CONNECT PHASE I CLINICAL TRIALS. Neuro-Oncology.2024; 84:b024.
. Abstract B024: Single cell transcriptomics and patient-derived tumoroids reveal that hepatobiliary lineage programs cooperate with Wnt pathway mutations to drive cell proliferation in hepatoblastoma. Cancer Research.A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma. Nature Communications. 2024; 15:10007.
.Chaetocin-mediated SUV39H1 inhibition targets stemness and oncogenic networks of diffuse midline gliomas and synergizes with ONC201. Neuro-Oncology. 2024; 26:735-748.
.2024; 21.
. Room To Grow: Bosutinib Approved for Newly Diagnosed or Relapsed/Intolerant Pediatric Chronic Myeloid Leukemia.