Zhao Lab

Publications

Ruffolo, B; Vicente-Muñoz, S; Mehta, KY; Rivera-Cruz, CM; Zhao, X; Romick, L; Setchell, KD R; Lane, A; Wells, SI. The Fanconi Anemia Pathway Inhibits mTOR Signaling and Prevents Accelerated Translation in Head and Neck Cancer Cells. Cancers. 2025; 17:2583.

Zhao, J; Zhao, X; Mizuno, T; Irie, K; Devarajan, P; Brunner, HI; Setchell, KD R. Volumetric Absorptive Microsampling Combined with Mass Spectrometry to Support Pharmacokinetically-Guided Precision Dosing of Mycophenolate Mofetil in Pediatric Lupus Nephritis Patients. The journal of applied laboratory medicine. 2025; 10:806-819.

Agarwal, P; Sampson, A; Hueneman, K; Choi, K; Jakobsen, NA; Uible, E; Ishikawa, C; Yeung, J; Bolanos, L; Zhao, X; Galloway-Pena, J; Byrd, JC; Vyas, P; Starczynowski, DT. Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1. Nature. 2025; 642:201-211.

Ahmed, F; Zhao, X; Beres, R; Garlapally, V; Mouzaki, M; Setchell, KD; Husain, SZ; Abu-El-Haija, M. Sa1442: LIPIDOMIC AND METABOLOMIC INSIGHTS INTO PEDIATRIC CHRONIC PANCREATITIS: DECIPHERING THE METABOLIC LANDSCAPE. Gastroenterology. 2025; 169:s-471.

Schenker, RB; Ramirez, CB; Jang, C; Allayee, H; Zhao, X; Setchell, KD R; Kohli, R; Goran, MI. Dihydroxyacetone phosphate is a novel predictor of hepatic fibrosis in Latino adolescents with obesity. Journal of Pediatric Gastroenterology and Nutrition. 2025; 80:174-181.

Hegde, S; Akbar, H; Wellendorf, AM; Nestheide, S; Johnson, JF; Zhao, X; Setchell, KD; Zheng, Y; Cancelas, JA. Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets. Blood. 2024; 144:1732-1746.

Zulqarnain, F; Zhao, X; Setchell, KD R; Sharma, Y; Fernandes, P; Srivastava, S; Shrivastava, A; Ehsan, L; Jain, V; Raghavan, S; Brown, DE; Moore, SR; Ali, SA; Syed, S. Machine-learning-based integrative -'omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction. iScience. 2024; 27:110013.

Koo, J; Langenberg, L; Luebbering, N; Strecker, L; Abdullah, S; Carusone, E; Deavy, M; Hoerth, C; Miller, G; Turner, D; Ziady, AG; Myers, KC; Jodele, S; Davies, SM. Ceramides Are Elevated in Transplant-Associated Thrombotic Microangiopathy in Hematopoietic Stem Cell Transplant Recipients and Are a Druggable Target for Prophylaxis. Transplantation and Cellular Therapy. 2024; 30:s17-s18.

Orkin, S; Zhao, X; Setchell, KD R; Carr, E; Arce-Clachar, AC; Bramlage, K; Huang, R; Fei, L; Beck, AF; Fawaz, R; Valentino, PL; Xanthakos, SA; Mouzaki, M. Food Insecurity and Pediatric Nonalcoholic Fatty Liver Disease Severity. The Journal of Pediatrics. 2024; 265:113818.

Zhao, J; Setchell, KD R; Zhao, X; Galandi, S; Garr, BA N; Gao, Z; Chin, C; Stark, S; Steele, PE; Ryan, TD. Use of volumetric absorptive microsampling and parallel reaction monitoring mass spectrometry for tacrolimus blood trough measurements at home in pediatric heart transplant patients. Journal of Mass Spectrometry and Advances in the Clinical Lab. 2024; 31:1-7.

Astrinidis, A; Li, C; Zhang, EY; Zhao, X; Zhao, S; Guo, M; Olatoke, T; Mattam, U; Huang, R; Zhang, AG; Setchell, KD R; McCormack, FX; Xu, Y; Yu, JJ. Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex. JCI insight. 2023; 8:e166850.

Narvaez-Rivas, M; Setchell, KD R; Galandi, SL; Zhao, X; Iqbal, NT; Ahmed, S; Iqbal, J; Syed, S; Ali, SA; Moore, SR. Essential Fatty Acid Deficiency Associates with Growth Faltering and Environmental Enteric Dysfunction in Children. Metabolites. 2023; 13:489.

Barnard, ND; Kahleova, H; Holtz, DN; Znayenko-Miller, T; Sutton, M; Holubkov, R; Zhao, X; Galandi, S; Setchell, KD R. A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial. Menopause: The Journal of the North American Menopause Society. 2023; 30:80-87.

Zhao, X; Zhang, W; Vig, P; Kostrub, C; Setchell, KD R. Serum Bile Acid Profiling and Mixed Model Analysis Reveal Biomarkers Associated with Pruritus Reduction in Maralixibat-Treated Patients with BSEP Deficiency. Metabolites. 2022; 12:952.

Zhao, X; Setchell, KD R; Huang, R; Mallawaarachchi, I; Ehsan, L; Dobrzykowski, E; Zhao, J; Syed, S; Ma, JZ; Iqbal, NT; Haberman, Y; Denson, LA; Ali, SA; Moore, SR. Bile Acid Profiling Reveals Distinct Signatures in Undernourished Children with Environmental Enteric Dysfunction. The Journal of nutrition. 2021; 151:3689-3700.