Brugmann Lab

C.F. Chang, E.N. Schock, E.A. O’Hare, J. Dodgson, H.H. Cheng, W.M. Muir, R.E. Edelmann, M.E. Delany, S.A. Brugmann. The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant, talpid² . Development. 2014 Aug; 141(15):3003-12.

S.A. Brugmann and J.M. Wells. Building additional complexity to in vitro derived intestinal tissues . Stem Cell Res Ther.  2013; 4 Suppl 1:S1.

H. Liu, Y. Lan, J. Xu, C.F. Chang, S.A. Brugmann, R. Jiang (2013). Odd-skipped related-1 controls neural crest chondrogenesis during tongue development . Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18555-60.

K.E. Powder, Y-C Ku, S.A. Brugmann, R.A. Veile, N.A. Renaud, J.A. Helms, M. Lovett. (2012). A Cross-Species Analysis of MicroRNAs in the Developing Avian Face .  PLoS ONE . 2012; 7(4):e35111.

A.L. Chang, G. Atzmon, A. Bergman, S. Brugmann, S.X. Atwood, H.Y. Chang, N. Barzilai. Identification of Genes Promoting Skin Youthfulness by Genome-Wide Association Study. J Invest Dermatol. 2014 Mar; 134(3):651-7.

A. Rada-Iglesias, R. Bajpai, S. Prescott, S.A. Brugmann, T. Swigut, J. Wysocka. Epigenomic annotation of enhancer elements predicts transcriptional regulators of human neural crest. Cell Stem Cell. 2012 Nov 2;11(5):633-48.

K. Lenton, A.W. James, A. Manu, S.A Brugmann, D. Birker, E.R. Nelson, P. Leucht, J.A. Helms, M.T. Longaker. Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling. Genesis. 2011 Oct;49(10):784-96.

B. Levi, A.W. James, E.R. Nelson, S.A. Brugmann, M. Sorkin, A. Manu, M.T. Longaker. Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90.

N.A. Zaghloul and S.A. Brugmann. The emerging face of primary cilia. Genesis. 2011 Apr;49(4):231-46.

A. Rada-Iglesias, R. Bajpai, T. Swigut, S.A. Brugmann, R.A. Flynn, J. Wysocka. A unique chromatin signature uncovers early developmental enhancers in humans. Nature. 2011 Feb 10;470(7333):279-83.

D.R. Cordero, S. Brugmann, Y. Chu, R. Bajpai, M. Jame, J.A. Helms. (2011). Cranial neural crest cells on the move: Their roles in craniofacial development. Am J Med Genet A. 2011 Feb;155A(2):270-9.

B. Levi, S. Brugmann,  M.T. Longaker. Discussion: Hes1 is required for the development of craniofacial structures derived from ectomesenchymal neural crest cells. J Craniofac Surg. 2010 Sep;21(5):1450-1.

S.A. Brugmann, D.R. Cordero, J.A. Helms. Craniofacial ciliopathies: A new classification for craniofacial disorders. Am J Med Genet Part A. 2010 Dec;152A(12):2995-3006.

S.A. Brugmann, N. C. Allen, Z. Mekonnen, E. Madan, J.A. Helms. A primary cilia-dependent etiology for midline facial disorders. Hum Mol Genet. 2010 Apr 15;19(8):1577-92.

S.A. Brugmann*, K.A. Powder*, N. Young, L.H. Goodnough, S.M. Hahn, A.W. James, J.A. Helms, M. Lovett. Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders. Hum Mol Genet. 2010 Mar 1;19(5):920-30.

C.T. Anderson, A.B. Castillo, S.A. Brugmann, J.A. Helms, C.R. Jacobs, T. Sterns. Primary Cilia: Cellular Sensors for the Skeleton. Anat Rec (Hoboken). 2008 Sep;291(9):1074-8.

G. Schlosser, T. Awtry, S.A. Brugmann, E. D. Jensen, K. Neilson, G. Ruan, A. Stammler, D. Voelker, B. Yan, C. Zhang, M. W. Klymkowsky, S. A. Moody. Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion. Dev Biol. 2008 Aug 1; 320(1):199-214.

J.A. Helms and S.A. Brugmann. The origins of species-specific facial morphology: The proof is in the pigeon. Integr Comp Biol. 2007 Sep; 47(3):338-42.

S.A. Brugmann, L.H. Goodnough, A. Gregorieff, P. Leucht, D. ten Berge, C. Fuerer, H. Clevers, R. Nusse, and J.A. Helms. Wnt signaling mediates regional specification in the vertebrate face. Development. 2007 Sep; 134(18):3283-95.

S.A. Brugmann, J. Kim and J.A. Helms. Looking different: towards an understanding diversity in facial form. Am J Med Genet A. 2006 Dec 1; 140(23):2521-9.

S.A. Brugmann, M.D. Tapadia and J.A. Helms. The Molecular Origins of Species-Specific Facial Pattern. Curr Top Dev Biol. 2006; 73:1-42.

S.A. Brugmann and S.A. Moody. (2005). Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs. Biol Cell. 2005 May; 97(5):303-19. (Cover)

S.A. Brugmann, P.D. Pandur, K.L. Kenyon, F. Pignoni and S.A. Moody. (2004). Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. Development. 2004 Dec; 131(23):5871-81.

C.F. Chang, E.N. Schock, D.A. Billmire and S.A. Brugmann. ^“Craniofacial syndromes: etiology, impact and treatment” Principles of Developmental Genetics, 2nd Edition . Ed. Sally A. Moody. Elsevier, New York. 2014. 654-671.

M. Jame, S.A. Brugmann and J.A. Helms. “Embryology of the craniofacial complex” Plastic Surgery 3^rd Edition Vol. 3 Head & Neck . Ed. Joe Losee. Elsevier, New York. 2012.

S.A. Brugmann, R.R. Amasha, D.M. Gupta, J.A. Helms. “Craniofacial Patterning and Dysmorphologies” Craniofacial Growth and Development . Ed. Jeremy J. Mao and Hyun-duck Nah. Iowa State University Press. 2009. 320.

J. A. Helms, S.A. Brugmann, and D.R. Cordero. “Shh and Other Genes and the Holoprosencephaly Malformation Sequence” Inborn Errors of Development Second Edition . Ed. Charles J. Epstein, Robert P. Erickson, and Anthony Wynshaw-Boris. Oxford University Press, London. 2008. 291-300.

S.A. Brugmann and J.A. Helms. "Craniofacial formation and congenital defects" Principles of Developmental Genetics . Ed. Sally A. Moody. Elsevier, New York. 2007. 656-679.