Brugmann Lab

Elliott, KH; Brugmann, SA. Sending mixed signals: Cilia-dependent signaling during development and disease. Developmental Biology. 2019; 447:28-41.

Metzler, MA; Raja, S; Elliott, KH; Friedl, RM; Tran, NQ H; Brugmann, SA; Larsen, M; Sandell, LL. RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation. Development (Cambridge). 2018; 145:dev164822-dev164822.

Elliott, KH; Millington, G; Brugmann, SA. A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development. Developmental Dynamics. 2018; 247:818-831.

Sehock, EN; Brugmann, SA. Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. Developmental Biology. 2017; 431:168-178.

Schock, EN; Brugmann, SA. Discovery, Diagnosis, and Etiology of Craniofacial Ciliopathies. Cold Spring Harbor Perspectives in Biology. 2017; 9:a028258-a028258.

Millington, G; Elliott, KH; Chang, Y; Chang, C; Dlugosz, A; Brugmann, SA. Cilia-dependent GLI processing in neural crest cells is required for tongue development. Developmental Biology. 2017; 424:124-137.

Schock, EN; Struve, JN; Chang, C; Williams, TJ; Snedeker, J; Attia, AC; Stottmann, RW; Brugmann, SA. A tissue-specific role for intraflagellar transport genes during craniofacial development. PLoS ONE. 2017; 12:e0174206-e0174206.

Snedeker, J; Schock, EN; Struve, JN; Chang, C; Cionni, M; Tran, PV; Brugmann, SA; Stottmann, RW. Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. PLoS ONE. 2017; 12:e0173258-e0173258.

Workman, MJ; Mahe, MM; Trisno, S; Poling, HM; Watson, CL; Sundaram, N; Chang, C; Schiesser, J; Aubert, P; Stanley, EG; et al. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nature Medicine. 2017; 23:49-59.

Chang, C; Chang, Y; Millington, G; Brugmann, SA. Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. PLoS Genetics. 2016; 12:e1006351-e1006351.

Chang, Y; Chaturvedi, P; Schock, EN; Brugmann, SA. Understanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid(2). Frontiers in Physiology. 2016; 7.

Schock, EN; Chang, C; Youngworth, IA; Davey, MG; Delany, ME; Brugmann, SA. Utilizing the chicken as an animal model for human craniofacial ciliopathies. Developmental Biology. 2016; 415:326-337.

Romick-Rosendale, LE; Hoskins, EE; Vinnedge, LM P; Foglesong, GD; Brusadelli, MG; Potter, SS; Komurov, K; Brugmann, SA; Lambert, PF; Kimple, RJ; et al. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling. Clinical Cancer Research. 2016; 22:2062-2073.

Schock, EN; Chang, C; Struve, JN; Chang, Y; Chang, J; Delany, ME; Brugmann, SA. Using the avian mutant talpid(2) as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome. DMM Disease Models and Mechanisms. 2015; 8:855-U547.

Saal, HM; Prows, CA; Guerreiro, I; Donlin, M; Knudson, L; Sund, KL; Chang, C; Brugmann, SA; Stottmann, RW. A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia. Human Molecular Genetics. 2015; 24:3399-3409.