Leukemia Research Studies

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AML New Diagnosis

AAML1331: A Phase III Study for Patients With Newly Diagnosed Acute Promyelocytic Leukemia (APL) Using Arsenic Trioxide and All-trans Retinoic Acid

  • Ages: From 1 to 21 years old

PURPOSE: This phase III trial studies tretinoin and arsenic trioxide in treating patients with newly diagnosed acute promyelocytic leukemia. Standard treatment for acute promyelocytic leukemia involves high doses of a common class of chemotherapy drugs called anthracyclines, which are known t ...More

AAML1531: Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome

  • Ages: From 3 to 36 months old

PURPOSE: This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killin ...More

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To learn more about available leukemia clinical trials, contact us at cancer@cchmc.org or 513-636-2799.