Leukemia Research Studies

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AML New Diagnosis

AAML1531: Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome

  • Ages: From 3 to 36 months old

PURPOSE: This phase III trial studies response-based chemotherapy in treating newly diagnosed acute myeloid leukemia or myelodysplastic syndrome in younger patients with Down syndrome. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killin ...More

Venetoclax Combined with Vyxeos for Relapsed/Refractory Acute Leukemia

  • Ages: 1 Year to 39 Years

This study evaluates the safety and tolerability of combining venetoclax with Vyxeos (CPX-351) in pediatric and young adult patients with acute leukemia that has come back or no responded to treatment. This is a single-institution Phase I pilot study designed to test the safety and tolerability of c ...More

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To learn more about available leukemia clinical trials, contact us at cancer@cchmc.org or 513-636-2799.