The Cincinnati Children’s Molecular Genetics Laboratory, in conjunction with Jorge Bezerra, MD, and the Division of Gastroenterology, introduces new Liver Panels by Next-Generation Sequencing (NGS).
The Heritable Liver Disease Genetic Testing program at
Cincinnati Children’s originated with the development of the revolutionary
JaundiceChip resequencing array. Now our
program has broadened its scope with the advent of our new Liver Panels by Next-Generation
Sequencing (NGS). The Liver Panels will meet
your patients' specialized needs by offering a comprehensive genetic test menu for
the diagnosis of an expansive range of heritable liver diseases.
The Liver Panels are comprised of 22 clinically relevant genes related
to heritable liver diseases. We have
created six custom assays to correlate with your patients' unique clinical
symptoms. The Liver Panels include the
following genetic test options:
Download: Liver Panels test spec sheet | Heritable Liver Disease test requisition
The Liver Panels use TruSeq Custom Amplicon (TSCA) capture
and enrichment technology followed by
next-generation sequencing to provide increased test sensitivity while
maintaining the same rapid, comprehensive and cost effective analysis you have
come to expect. Our team of pediatric gastroenterologists and molecular
geneticists will review and interpret each customized analysis, giving you
access to unparalleled clinical expertise.
The Molecular Genetics Laboratory at Cincinnati Children's
also offers single gene diagnostic testing and deletion / duplication analysis
for the genes included in the Liver Panels. See a comprehensive list of tests offered.
Why Choose Us?
Our lab will give you access to unparalleled clinical
expertise. We provide guidance
- Clinical interpretation, recommendation for follow-up
testing and medical management
- Genetic counseling
- Coordination of studies for at-risk family members