The Rett Syndrome Clinic at Cincinnati Children's provides comprehensive, multidisciplinary care for children and adults with Rett syndrome and related spectrum disorders. Our specialists work collaboratively to diagnose and manage patients’ complex neurological and medical needs, with the goal of enhancing quality of life for them and their families.

We provide evaluation and treatment for all variations of Rett syndrome and related MECP2 spectrum disorders, including:

  • Typical Rett syndrome
  • Rett-related disorders
    • X-linked CDKL5 gene mutation
    • Chromosome 14 FOXG1 gene mutation
    • Other disorders, such as mild, late regression and preserved speech variants
    • MECP2 gene mutations without fulfilling Rett criteria
    • Males with MECP2 gene mutations
  • MECP2 duplication disorder