As a molecular epidemiologist, I am engaged in researching pediatric allergic diseases. My special interests include asthma and food allergy, allergic disease progression, and the genomic and environmental contributions to allergic diseases in children. I was drawn to these research areas after growing up with seasonal allergies and asthma, and by my love of pediatric research.
In the Biagini Lab, our long-term goals are to improve the health of children by conducting research that advances the field of asthma and allergic disease research by investigating the interplay of genetics with environmental exposures. We are also studying the mechanisms underlying the progression of disease from food allergy to asthma and the biology underlying severe asthma in children.
We recently published the Pediatric Asthma Risk Score (PARS), which is the first continuous risk score for asthma in children. It relies on factors that are routinely collected in the assessment of a child being evaluated for allergy, asthma or both. It is superior to the traditional Asthma Predictive Index (API) with an 11% increase in sensitivity due to improved prediction in children with mild-to-moderate asthma risk.
I am an elected member to the American Academy of Asthma, Allergy and Immunology and a member of the editorial board for the Journal of Asthma. I began my career in 2001 and joined the Cincinnati Children’s team in 2008.