Questions about COVID-19?

What Patients & Families Need to Know | New Visitor PolicyGuidance for Community Healthcare Providers

A photo of Samantha Brugmann.

Member, Division of Plastic Surgery

Associate Professor, UC Department of Surgery

513-636-1599

Biography & Affiliation

Biography

Samantha A. Brugmann, PhD, is an associate professor of pediatrics in the Divisions of Plastic Surgery and Developmental Biology within the University of Cincinnati College of Medicine. She received her BS in cell and molecular biology from Tulane University in New Orleans, LA. She then obtained her PhD in genetics from George Washington University in Washington, DC where she studied cranial sensory placode development in Xenopus laevis. She performed her postdoctoral fellowship at Stanford University where her research focused on craniofacial development. While at Stanford she received a Ruth L. Kirschstein National Research Service Awards for Individual Postdoctoral Fellows (F32), a Pediatric Research Fund-Child Health Research Program Grant and a NIH Pathway to Independence Award (K99/R00). She joined Cincinnati Children’s Hospital Medical Center in January 2011 to study craniofacial development and disease.

Research Interests

Craniofacial development

Academic Affiliation

Associate Professor, UC Department of Surgery

Departments

Plastic Surgery, Developmental Biology

Education

BS: Tulane University, New Orleans, LA.

PhD: George Washington University, Washington DC.

Fellowship: Stanford University, Stanford, CA.

Publications

Sending mixed signals: Cilia-dependent signaling during development and disease. Elliott, KH; Brugmann, SA. Developmental Biology. 2019; 447:28-41.

RDH10-mediated retinol metabolism and RARα-mediated retinoic acid signaling are required for submandibular salivary gland initiation. Metzler, MA; Raja, S; Elliott, KH; Friedl, RM; Tran, NQ H; Brugmann, SA; Larsen, M; Sandell, LL. Development (Cambridge). 2018; 145:dev164822-dev164822.

A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development. Elliott, KH; Millington, G; Brugmann, SA. Developmental Dynamics. 2018; 247:818-831.

Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. Sehock, EN; Brugmann, SA. Developmental Biology. 2017; 431:168-178.

Discovery, Diagnosis, and Etiology of Craniofacial Ciliopathies. Schock, EN; Brugmann, SA. Cold Spring Harbor Perspectives in Biology. 2017; 9:a028258-a028258.

Cilia-dependent GLI processing in neural crest cells is required for tongue development. Millington, G; Elliott, KH; Chang, Y; Chang, C; Dlugosz, A; Brugmann, SA. Developmental Biology. 2017; 424:124-137.

A tissue-specific role for intraflagellar transport genes during craniofacial development. Schock, EN; Struve, JN; Chang, C; Williams, TJ; Snedeker, J; Attia, AC; Stottmann, RW; Brugmann, SA. PLoS ONE. 2017; 12:e0174206-e0174206.

Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. Snedeker, J; Schock, EN; Struve, JN; Chang, C; Cionni, M; Tran, PV; Brugmann, SA; Stottmann, RW. PLoS ONE. 2017; 12:e0173258-e0173258.

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Workman, MJ; Mahe, MM; Trisno, S; Poling, HM; Watson, CL; Sundaram, N; Chang, C; Schiesser, J; Aubert, P; Stanley, EG; et al. Nature Medicine. 2017; 23:49-59.

Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. Chang, C; Chang, Y; Millington, G; Brugmann, SA. PLoS Genetics. 2016; 12:e1006351-e1006351.