A photo of Don Hayes Jr.

Don Hayes, Jr., MD, MS, MEd, MBA

  • Medical Director, Lung Transplant Program
  • Pulmonologist, Division of Pulmonary Medicine
  • Professor, UC Department of Pediatrics



Lung disease in children and young adults presents a unique challenge in diagnosis and treatment. My own experiences with childhood asthma and my early clinical experiences as a medical student sparked my interest in helping young people suffering from respiratory diseases. We can always improve the care of those with lung disease, and I am passionate about finding how to do that through research.

As the medical director of the Lung Transplant Program at Cincinnati Children’s Hospital Medical Center, I specialize in treating patients affected by advanced lung disease, end-stage lung failure, pulmonary vascular disorders and cystic fibrosis. I care for children and young adults before and after lung transplant.

My research currently focuses on the role of the immune system in the lungs and how it contributes to the progression of lung disease and affects lung allografts in patients who have undergone a lung transplant. Some of my work also includes trying to identify biomarkers to help diagnose lung diseases and pulmonary vascular disorders earlier so we can start therapies sooner.

I serve on three editorial boards and am also a member of numerous national organizations that focus on lung diseases. To date, I have published over 500 peer-reviewed articles, abstracts and book chapters. I have also delivered more than 130 presentations about lung disease in the United States and around the world.

I am dedicated to delivering the highest quality healthcare with a humanistic approach. My induction into the Gold Humanism Honor Society was a particularly special moment in my clinical career.

MD: University of Kentucky, Lexington, KY, 1998.

Residency: Combined Internal Medicine and Pediatrics, East Carolina University Brody School of Medicine, Greenville, NC, 2002.

Fellowship: Combined Pediatric Pulmonology and Adult Pulmonary Disease, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2006.

Certification: Pediatrics; Pediatric Pulmonology; Internal Medicine; Adult Pulmonary Disease.


Advanced lung disease; cystic fibrosis; lung transplantation; pulmonary vascular disease

Services and Specialties

Lung Transplant Program, Pulmonary Medicine, Cystic Fibrosis Center


Lung immunology; pulmonary infections; biomarker development

Research Areas

Pulmonary Medicine

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The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-second pediatric lung and heart-lung transplantation report-2019; Focus theme: Donor and recipient size match. Hayes, D; Cherikh, WS; Chambers, DC; Harhay, MO; Khush, KK; Lehman, RR; Meiser, B; Rossano, JW; Hsich, E; Potena, L; Sadavarte, A; Singh, TP; Zuckermann, A; Stehlik, J; International Society for Heart and Lung Transplan, . Journal of Heart and Lung Transplantation. 2019; 38:1015-1027.


Lung Allocation Score Thresholds Prioritize Survival After Lung Transplantation. Li, SS; Miller, R; Tumin, D; Stewart, WC L; Tobias, JD; Hayes, D. Chest. 2019; 156:64-70.


Transplant outcomes for idiopathic pulmonary hypertension in children. Hubbard, R; Miller, R; Tumin, D; Tobias, JD; Hayes, D. Journal of Heart and Lung Transplantation. 2019; 38:580-581.


Cell Therapy for Cystic Fibrosis Lung Disease: Regenerative Basal Cell Amplification. Hayes, D; Kopp, BT; Hill, CL; Lallier, SW; Schwartz, CM; Tadesse, M; Alsudayri, A; Reynolds, SD. Stem cells translational medicine. 2019; 8:225-235.


Home Oxygen Therapy for Children. An Official American Thoracic Society Clinical Practice Guideline. Jr, HD; Wilson, KC; Krivchenia, K; Hawkins, SM M; Balfour-Lynn, IM; Gozal, D; Panitch, HB; Splaingard, ML; Rhein, LM; Kurland, G; Kaley, D; Gettys, A; Deterding, RR; Pediat, AT S A. American Journal of Respiratory and Critical Care Medicine. 2019; 199:e5-e23.


Transplant center volume and outcomes in lung transplantation for cystic fibrosis. Hayes, D; Sweet, SC; Benden, C; Kopp, BT; Goldfarb, SB; Visner, GA; Mallory, GB; Tobias, JD; Tumin, D. Transplant International. 2017; 30:371-377.


Lung Transplant Center Volume Ameliorates Adverse Influence of Prolonged Ischemic Time on Mortality. Jr, HD; Hartwig, MG; Tobias, JD; Tumin, D. American Journal of Transplantation. 2017; 17:218-226.


Influence of graft ischemic time and geographic distance between donor and recipient on survival in children after lung transplantation. Hayes, D; Joy, BF; Reynolds, SD; Tobias, JD; Tumin, D. Journal of Heart and Lung Transplantation. 2016; 35:1220-1226.


Age-related survival disparity associated with lung transplantation in cystic fibrosis: An analysis of the registry of the International Society for Heart and Lung Transplantation. Hayes, D; Glanville, AR; McGiffin, D; Tobias, JD; Tumin, D. Journal of Heart and Lung Transplantation. 2016; 35:1108-1115.


Impact of pulmonary hypertension on survival in patients with cystic fibrosis undergoing lung transplantation: an analysis of the UNOS registry. Hayes, D; Higgins, RS; Kirkby, S; McCoy, KS; Wehr, AM; Lehman, AM; Whitson, BA. Journal of Cystic Fibrosis. 2014; 13:416-423.

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