A photo of Nadine Kasparian.

Nadine A. Kasparian, PhD, MAPS


  • Director, Heart and Mind Wellbeing Center
  • Member, Division of Behavioral Medicine and Clinical Psychology
  • Professor, UC Department of Pediatrics

About

Biography

Nadine Kasparian is professor of Pediatrics and director of the Heart and Mind Wellbeing Center and the Center for Heart Disease and Mental Health Research.

Nadine's research investigates the factors that shape emotional and neurobiological development in children with critical or chronic illness, particularly congenital heart disease (CHD). Her team seeks to understand how experiences of early medical adversity may alter developmental processes, including emotion regulation and stress reactivity, in ways that increase vulnerability to anxiety, depression and other mental health difficulties. Nadine's team also explores infant-parent bonding and attachment, and the ways in which we can best support young children and their families in the context of medical illness. In partnership with patients, parents and health care providers, the overarching goal is to discover the mechanisms that contribute to developmental risk and resilience, and deliver targeted interventions, strategies and policies to promote health and wellbeing throughout childhood and across the life course. Her team pursues this research using methods drawn from clinical and developmental psychology, neurobiology and medical science.

Nadine has a PhD in medical psychology from the University of Sydney and serves on the editorial board for Health Psychology Review and Psychology & Health. She holds a National Heart Foundation of Australia Future Leader Fellowship (2017-2020), has been continuously funded by the National Health & Medical Research Council (NHMRC) of Australia, and was awarded a Harkness Fellowship in Health Care Policy and Practice based at Harvard Medical School (2018-2019). In 2018 her team received the Sydney Children's Hospitals Network Innovation Award for Excellence in the Provision of Mental Health Services for children with heart disease and their families.

BA: Psychology (Honors Class I), University of Sydney, Australia.

PhD: Medical Psychology, University of Sydney, Australia.

Licensed: Psychology Board of Australia.

Full Member: Australian Psychological Society.

Graduate Diploma: Perinatal and Infant Mental Health, NSW Institute of Psychiatry, Australia.

Interests

Emotional and mental healthcare of those affected by heart disease, childhood heart disease; congenital heart disease; mental health; wellbeing; infant mental health; child mental health; perinatal mental health; parent mental health; bonding; attachment; neurodevelopment; neurobehavior; emotion regulation; prenatal anxiety; prenatal depression; postnatal anxiety; postnatal depression; parenting; family functioning; anxiety; depression; trauma; traumatic stress; adverse childhood experiences; empathy; resilience; adaptation; psychotherapy; psychological intervention; trauma-informed care; psychologically-informed care; integrated care; mental health care

Interests

Emotional and mental healthcare of those affected by heart disease; mental health; neurodevelopment; neurobiological responses to stress; heart-brain-gut axis; brain imaging; hypothalamus-pituitary-adrenal (HPA) axis; microbiome; biomarkers; biobank; stress reactivity; pregnancy; child development; intervention; randomized controlled trials; prospective cohort studies; qualitative research; acceptability and feasibility studies; psychotherapy; clinical research; translational research; health services; health policy

Research Areas

Behavioral Medicine, Heart

Publications

Selected

Parent-child bonding and attachment during pregnancy and early childhood following congenital heart disease diagnosis. Tesson, S; Butow, PN; Marshall, K; Fonagy, P; Kasparian, NA. Health Psychology Review. 2022; 16:378-411.

Selected

A mediated model of mindful awareness, emotion regulation, and maternal mental health during pregnancy and postpartum. McDonald, HM; Sherman, KA; Kasparian, NA. Australian Journal of Psychology. 2021; 73:368-380.

Selected

Factors associated with psychological distress among Australian women during pregnancy. McDonald, HM; Sherman, KA; Kasparian, NA. Personality and Individual Differences. 2021; 172:110577.

Selected

Maintaining Momentum in Infant Mental Health Research During COVID-19: Adapting Observational Assessments. Tesson, S; Swinsburg, D; Kasparian, NA. Journal of Pediatric Psychology. 2021; 46:254-263.

Selected

Neurocognitive Dysfunction and Smaller Brain Volumes in Adolescents and Adults With a Fontan Circulation. Verrall, CE; Yang, JY M; Chen, J; Schembri, A; D'Udekem, Y; Zannino, D; Kasparian, NA; Du Plessis, K; Grieve, SM; Welton, T; et al. Circulation. 2021; 143:878-891.

Selected

Prevalence and Prognostic Association of a Clinical Diagnosis of Depression in Adult Congenital Heart Disease: Results of the Boston Adult Congenital Heart Disease Biobank. Carazo, MR; Kolodziej, MS; DeWitt, ES; Kasparian, NA; Newburger, JW; Duarte, VE; Singh, MN; Opotowsky, AR. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease. 2020; 9:e014820.

Selected

Benefits of a brief psychological intervention targeting fear of cancer recurrence in people at high risk of developing another melanoma: 12-month follow-up results of a randomized controlled trial. Dieng, M; Morton, RL; Costa, DS J; Butow, PN; Menzies, SW; Lo, S; Mann, GJ; Cust, AE; Kasparian, NA. British Journal of Dermatology. 2020; 182:860-868.

Selected

How Patient Perceptions Shape Responses and Outcomes in Inherited Cardiac Conditions. O'Donovan, C; Ingles, J; Broadbent, E; Skinner, JR; Kasparian, NA. Heart, Lung and Circulation. 2020; 29:641-652.

Selected

Health-Related Quality of Life in Children, Adolescents, and Adults With a Fontan Circulation: A Meta-Analysis. Marshall, KH; D'Udekem, Y; Sholler, GF; Opotowsky, AR; Costa, DS J; Sharpe, L; Celermajer, DS; Winlaw, DS; Newburger, JW; Kasparian, NA. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease. 2020; 9:e014172.

Selected

Management of People With a Fontan Circulation: a Cardiac Society of Australia and New Zealand Position statement. Zentner, D; Celermajer, DS; Gentles, T; d'Udekem, Y; Ayer, J; Blue, GM; Bridgman, C; Burchill, L; Cheung, M; Cordina, R; et al. Heart, Lung and Circulation. 2020; 29:5-39.

From the Blog

Cincinnati Children’s Opens Nation’s First Heart and Mind Wellbeing Center
Heart and Lung

Cincinnati Children’s Opens Nation’s First Heart and Mind Wellbeing Center

Nadine Kasparian, PhD, MAPS1/24/2023

Mental Health Care Vital to Congenital Heart Disease Care
Heart and Lung

Mental Health Care Vital to Congenital Heart Disease Care

Nadine Kasparian, PhD, MAPS7/18/2022

Coping with the Emotional Challenges of Congenital Heart Disease
Blog Heart Conditions

Coping with the Emotional Challenges of Congenital Heart Disease

By Nadine Kasparian, PhD5/20/2022