My clinical specialty is inpatient psychiatric care of patients with autism and/or intellectual disability with comorbid severe behavior or severe mental illness. I also provide outpatient care for patients with Angelman syndrome and other neurodevelopmental disorders with significant medical comorbidities.
In addition, I treat patients with catatonia associated with neurodevelopmental disorders. I have always been interested in how the brain works and how changes in the brain relate to human behavior. I enjoy working with children and families with neurodevelopmental disorders. Since this population is often medically underserved, I can make a significant difference in patients' and families' overall quality of life.
My research areas are severe autism, intellectual disability, Angelman syndrome and monogenetic neurodevelopmental disorders. I have always been interested in exploring new ways of testing that uncover the brain's inner workings. In college, I researched language development in babies, adults and African grey parrots. My PhD focused on using MRI (specifically fMRI and MRS) to investigate changes in the brain associated with bipolar disorder. These earlier experiences underscore my current research in neurodevelopmental disorder.
Children with neurodevelopmental disorders and severe behavior are often excluded from traditional research studies due to their challenging behavior and medical comorbidities. As such, we have a dearth of knowledge about effective treatments for these patients. With advances in genetic testing, brain imaging and physiologic testing, we now have the opportunity to uncover more effective treatments targeted to the individual patient.
BS: Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA, 2000-2004.
Physician Scientist Training Program: University of Cincinnati College of Medicine, Cincinnati, OH, 2004-2013.
PhD: Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, 2009.
MD: University of Cincinnati College of Medicine, Cincinnati, OH, 2013.
Residency: Triple Board Program in Pediatrics, Psychiatry, and Child and Adolescent Psychiatry, Cincinnati Children’s Hospital Medical Center, 2013-2018.
Neurodevelopmental disorders; autism spectrum disorders; intellectual disability; profound autism; catatonia
Psychiatry
Angelman syndrome; profound autism; systems of mental health care
Psychiatry
P351: Genetic testing for patients with neurodevelopmental disorders in the inpatient psychiatry setting may reduce hospital stays and improve behavioral outcomes. 2024; 2:101245.
Systematic Review: Emotion Dysregulation in Syndromic Causes of Intellectual and Developmental Disabilities. Journal of the American Academy of Child and Adolescent Psychiatry. 2023; 62:518-557.
O29: Providing genetic evaluation and testing to patients with neurodevelopmental disorders in the inpatient psychiatry setting may reduce inpatient hospital stays*. 2023; 1:100406.
Pharmacological management of behavioral disturbances in children and adolescents with autism spectrum disorders. Current Problems in Pediatric and Adolescent Health Care. 2018; 48:250-264.
From Alert Child to Sleepy Adolescent: Age Trends in Chronotype, Social Jetlag, and Sleep Problems in Youth with Autism. Journal of Autism and Developmental Disorders. 2024; 54:4529-4539.
Return of genetic research results in 21,532 individuals with autism. Genetics in Medicine. 2024; 26:101202.
2.24 Orexin Receptor Antagonists for Treatment of Insomnia Associated With Neurodevelopmental Disorders. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63:s191.
An Institutional Approach to Equity and Improvement in Child Health Outcomes. Pediatrics. 2024; 154:e2023064994.
Neurodevelopmental Disorders Including Autism Spectrum Disorder and Intellectual Disability as a Risk Factor for Delayed Diagnosis of Catatonia. Journal of Developmental and Behavioral Pediatrics. 2024; 45:e137-e142.
Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder. Scientific Reports. 2023; 13:5192.
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