My clinical specialty is inpatient psychiatric care of patients with autism and/or intellectual disability with comorbid severe behavior or severe mental illness. I also provide outpatient care for patients with Angelman syndrome and other neurodevelopmental disorders with significant medical comorbidities.
In addition, I treat patients with catatonia associated with neurodevelopmental disorders. I have always been interested in how the brain works and how changes in the brain relate to human behavior. I enjoy working with children and families with neurodevelopmental disorders. Since this population is often medically underserved, I can make a significant difference in patients' and families' overall quality of life.
My research areas are severe autism, intellectual disability, Angelman syndrome and monogenetic neurodevelopmental disorders. I have always been interested in exploring new ways of testing that uncover the brain's inner workings. In college, I researched language development in babies, adults and African grey parrots. My PhD focused on using MRI (specifically fMRI and MRS) to investigate changes in the brain associated with bipolar disorder. These earlier experiences underscore my current research in neurodevelopmental disorder.
Children with neurodevelopmental disorders and severe behavior are often excluded from traditional research studies due to their challenging behavior and medical comorbidities. As such, we have a dearth of knowledge about effective treatments for these patients. With advances in genetic testing, brain imaging and physiologic testing, we now have the opportunity to uncover more effective treatments targeted to the individual patient.
BS: Brain and Cognitive Sciences, Massachusetts Institute of Technology (MIT), Cambridge, MA, 2000-2004.
Physician Scientist Training Program: University of Cincinnati College of Medicine, Cincinnati, OH, 2004-2013.
PhD: Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, 2009.
MD: University of Cincinnati College of Medicine, Cincinnati, OH, 2013.
Residency: Triple Board Program in Pediatrics, Psychiatry, and Child and Adolescent Psychiatry, Cincinnati Children’s Hospital Medical Center, 2013-present.
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Results of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder. Scientific Reports. 2023; 13.
Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome. Communications Biology. 2022; 5.
Brief Report: Telehealth Satisfaction Among Caregivers of Pediatric and Adult Psychology and Psychiatry Patients with Intellectual and Developmental Disability in the Wake of Covid-19. Journal of Autism and Developmental Disorders. 2022; 52:5253-5265.
3.28 Diverse Experiences During Regulating Together Emotion Dysregulation Treatment. Journal of the American Academy of Child and Adolescent Psychiatry. 2022; 61:s236-s237.
Systematic Review: Emotion Dysregulation in Syndromic Causes of Intellectual and Developmental Disabilities. Journal of the American Academy of Child and Adolescent Psychiatry. 2022.
A Collaborative Psychiatric-Genetics Inpatient Care Delivery Model Improves Access to Clinical Genetic Evaluation, Testing, and Diagnosis for Patients With Neurodevelopmental Disorders. Frontiers in Genetics. 2022; 13.
Management of Emotion Dysregulation and Outbursts in Children and Adolescents. Current Psychiatry Reports. 2022; 24:213-226.
Decades of Progress in the Psychopharmacology of Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. 2021; 51:4370-4394.
Letter to the Editor: Chlorpromazine-Induced Skin Pigmentation in a Pediatric Patient. Journal of Child and Adolescent Psychopharmacology. 2021; 31:516-517.
Case Report: Is Catatonia a Clinical Feature of the Natural Progression of NLGN2-Related Neurodevelopmental Disorder?. Journal of Autism and Developmental Disorders. 2021; 51:371-376.
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