A photo of Yu Lan.

Member, Division of Plastic Surgery

Associate Professor, UC Department of SurgeryUC Department of Pediatrics

513-803-7842

Biography & Affiliation

Biography

Yu Lan, PhD, is an associate professor of Surgery in the Division of Plastic Surgery at Cincinnati Children’s Hospital Medical Center within the UC Department of Surgery. Dr. Lan received graduate training in plant sciences and postdoctoral training in Drosophila Developmental Genetics and Mouse Molecular Genetics. Prior to joining Cincinnati Children’s in 2011, she was a faculty member in the Center for Oral Biology and Department of Biomedical Genetics at University of Rochester School of Medicine and Dentistry. She has directed and conducted multiple NIH-funded research projects on studies of the genetic basis and developmental mechanisms of structural birth defects. Her current research program focuses on understanding the molecular regulation of craniofacial and skeletal development.

Academic Affiliation

Associate Professor, UC Department of SurgeryUC Department of Pediatrics

Departments

Plastic Surgery, Developmental Biology

Education

BS: Sichuan University, Chengdu, China.

MS: Chinese Academy Sciences, Beijing, China.

PhD: University of Maine, Orono, ME.

Post-doc trainings: Wesleyan University, Middletown, CT; The Jackson Laboratory, Bar Harbor, ME.

Publications

Liu Z, Li C, Xu J, Lan Y, Liu H, Li X, Maire P, Wang X, Jiang R. Crucial and overlapping roles of Six1 and Six2 in craniofacial development. J Dent Res. 2019 Mar 24:22034519835204.

Xu J, Liu H, Lan Y, Adam M, Clouthier DF, Potter SS, Jiang R. Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. eLife. 2019;8:e40315.

Li C, Lan Y, Krumlauf R, Jiang R. Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice. J Dent Res. 2017;96(11):1273-1281.

Fu X, Xu J, Chaturvedi P, Liu H, Jiang R, Lan Y. Identification of Osr2 transcriptional target genes in palate development. J Dent Res. 2017;96(12):1451-1458.

Lan Y, Zhang N, Liu H, Xu J, Jiang R. Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development. 2016;143(13):2344-2355.

Lan Y, Jia S, Jiang R. Molecular patterning of the mammalian dentition. Seminars in Cell and Developmental Biology. 2014;25-26:61-70.

Baek J-A, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol. 2011;350:520-531.

Lan Y, Jiang R. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development. 2009;136:1387-1396.

Zhang Z, Lan Y, Chai Y, Jiang R. Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science. 2009;323:1232-1234.

Lan Y, Ovitt CE, Cho E-S, Maltby KM, Wang Q, Jiang R. Odd-skipped related-2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development. 2004;131:3207-3216.