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A photo of Yu Lan.

Member, Division of Plastic Surgery

Associate Professor, UC Department of SurgeryUC Department of Pediatrics

513-803-7842

Biography & Affiliation

Biography

Yu Lan, PhD, is an associate professor of Surgery in the Division of Plastic Surgery at Cincinnati Children’s Hospital Medical Center within the UC Department of Surgery. Dr. Lan received graduate training in plant sciences and postdoctoral training in Drosophila Developmental Genetics and Mouse Molecular Genetics. Prior to joining Cincinnati Children’s in 2011, she was a faculty member in the Center for Oral Biology and Department of Biomedical Genetics at University of Rochester School of Medicine and Dentistry. She has directed and conducted multiple NIH-funded research projects on studies of the genetic basis and developmental mechanisms of structural birth defects. Her current research program focuses on understanding the molecular regulation of craniofacial and skeletal development.

Academic Affiliation

Associate Professor, UC Department of SurgeryUC Department of Pediatrics

Divisions

Plastic Surgery, Developmental Biology

Education

BS: Sichuan University, Chengdu, China.

MS: Chinese Academy Sciences, Beijing, China.

PhD: University of Maine, Orono, ME.

Post-doc trainings: Wesleyan University, Middletown, CT; The Jackson Laboratory, Bar Harbor, ME.

Publications

Requirement of Hyaluronan Synthase-2 in Craniofacial and Palate Development. Lan, Y; Qin, C; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2019; 98:1367-1375.

Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development. Liu, Z; Li, C; Xu, J; Lan, Y; Liu, H; Li, X; Maire, P; Wang, X; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2019; 98:572-579.

Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. Xu, J; Liu, H; Lan, Y; Adam, M; Clouthier, DE; Potter, S; Jiang, R. eLife. 2019; 8.

Identification of Osr2 Transcriptional Target Genes in Palate Development. Fu, X; Xu, J; Chaturvedi, P; Liu, H; Jiang, R; Lan, Y. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1451-1458.

Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice. Li, C; Lan, Y; Krumlauf, R; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1273-1281.

Molecular and Cellular Mechanisms of Palate Development. Li, C; Lan, Y; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1184-1191.

Activin and Bmp4 Signaling Converge on Wnt Activation during Odontogenesis. Kwon, HE; Jia, S; Lan, Y; Liu, H; Jiang, R. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. 2017; 96:1145-1152.

Golga5 is dispensable for mouse embryonic development and postnatal survival. McGee, LJ; Jiang, AL; Lan, Y. Genesis: the Journal of Genetics and Development. 2017; 55:e23039-e23039.

Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Jia, S; Kwon, HE; Lan, Y; Zhou, J; Liu, H; Jiang, R. Developmental Biology. 2016; 420:110-119.

Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis. Xu, J; Liu, H; Chai, OH; Lan, Y; Jiang, R. PLoS ONE. 2016; 11:e0159597-e0159597.