Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition.
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Cell Stem Cell.
2020;
26:420-430.e6.
Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies.
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Journal of Allergy and Clinical Immunology.
2020;
145:907-921.e3.
Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
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Science Translational Medicine.
2019;
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Epigenetic Regulator Genes Direct the Fate of Multipotent Progenitor Cell of Origin in Lineage Switched MLL-AF4 Leukaemia.
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Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
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Cancer Cell.
2019;
35:677-691.e10.
Alternative translation initiation generates the N-terminal truncated form of RUNX1 that retains hematopoietic activity.
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Experimental Hematology.
2019;
72:27-35.
Improved chemotherapy modeling with RAG-based immune deficient mice.
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PLoS ONE.
2019;
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Improved multilineage human hematopoietic reconstitution and function in NSGS mice.
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PLoS ONE.
2018;
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Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response.
Barve, A; Casson, L; Krem, M; Wunderlich, M; Mulloy, JC; Beverly, LJ.
Experimental Hematology.
2018;
67:18-31.
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m(6)A Modification.
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