Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL.
Rodriguez, S; Abundis, C; Boccalatte, F; Mehrotra, P; Chiang, MY; Yui, MA; Wang, L; Zhang, H; Zollman, A; Bonfim-Silva, R; et al.
Leukemia.
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34:1241-1252.
Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition.
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Cell Stem Cell.
2020;
26:420-430.e6.
Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies.
Khodoun, MV; Morris, SC; Angerman, E; Potter, C; Schuman, R; Wunderlich, M; Maciag, JJ; Locker, KC S; Mulloy, JC; Herr, AB; et al.
Journal of Allergy and Clinical Immunology.
2020;
145:907-921.e3.
Improved chemotherapy modeling with RAG-based immune deficient mice.
Wunderlich, M; Manning, N; Sexton, C; Sabulski, A; Byerly, L; O'Brien, E; Perentesis, JP; Mizukawa, B; Mulloy, JC.
PLoS ONE.
2019;
14:e0225532-e0225532.
Overcoming adaptive therapy resistance in AML by targeting immune response pathways.
Melgar, K; Walker, MM; Jones, LM; Bolanos, LC; Hueneman, K; Wunderlich, M; Jiang, J; Wilson, KM; Zhang, X; Sutter, P; et al.
Science Translational Medicine.
2019;
11:eaaw8828-eaaw8828.
Epigenetic Regulator Genes Direct the Fate of Multipotent Progenitor Cell of Origin in Lineage Switched MLL-AF4 Leukaemia.
Tirtakusuma, R; Milne, P; Ptasinska, A; Meyer, C; Nakjang, S; Komkov, A; Williamson, D; Cauchy, P; Assi, S; Blair, H; et al.
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Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Huang, Y; Su, R; Sheng, Y; Dong, L; Dong, Z; Xu, H; Ni, T; Zhang, ZS; Zhang, T; Li, C; et al.
Cancer Cell.
2019;
35:677-691.e10.
Alternative translation initiation generates the N-terminal truncated form of RUNX1 that retains hematopoietic activity.
Goyama, S; Schibler, J; Mulloy, JC.
Experimental Hematology.
2019;
72:27-35.
Improved multilineage human hematopoietic reconstitution and function in NSGS mice.
Wunderlich, M; Chou, F; Sexton, C; Presicce, P; Chougnet, CA; Aliberti, J; Mulloy, JC.
PLoS ONE.
2018;
13:e0209034-e0209034.
Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response.
Barve, A; Casson, L; Krem, M; Wunderlich, M; Mulloy, JC; Beverly, LJ.
Experimental Hematology.
2018;
67:18-31.