For more than 40 years, Cincinnati Children’s has been a leader in caring for children with leukemia and lymphoma. Today, our Leukemia and Lymphoma Program is one of the nation’s largest and most technically advanced.

Our experienced cancer specialists treat children and young adults who have been recently diagnosed with leukemia or lymphoma, and those with high-risk, treatment-resistant or recurrent cancer. Conditions we treat include:

Our care team creates a personalized treatment plan for each patient. The plan may include chemotherapy, radiation therapy, surgery to remove some or all of the tumor, novel immune therapies, and blood or marrow transplantation. Patients have access to both national clinical research studies as well as research studies only available at Cincinnati Children’s.

What Sets Us Apart

Innovative Treatment Options

Cincinnati Children’s offers advanced immunotherapies for aggressive and treatment-resistant leukemias and lymphomas. These therapies work with a patient’s own immune system to stop or slow down the cancer, and sometimes lead to a cure. Some immunotherapies are already approved by the Food and Drug Administration (FDA), while others are available only through clinical trials. They are typically offered to patients whose cancer is recurrent or relapsed (comes back) or refractory (resists treatment).

One of the most exciting immunotherapies used to treat leukemia and lymphoma is called chimeric antigen receptor (CAR T-cell) therapy. CAR T uses infection-fighting cells (T cells) in the immune system to fight cancer cells. Cincinnati Children’s was one of the first pediatric hospitals to offer CAR T-cell therapy clinical trials. We have extensive experience providing CAR T-cell therapy for children and young adults.

Advanced Imaging Techniques

High-tech imaging techniques include simultaneous diagnostic computed tomography (CT) scans and positron emission tomography (PET) scans. This technology helps our cancer specialists provide more detailed, accurate diagnoses and staging information. A PET scan is a nuclear imaging test that can sometimes detect cancerous tissues and cells that other imaging tests cannot.

Genetic Testing

Patients with a high-risk or relapsed cancer undergo genetic testing of tumor tissue. This helps the team identify potential targets for novel anti-cancer drugs.

Cutting-Edge Radiation Therapy

We offer proton therapy, one of the most precise and advanced forms of radiation therapy available in the world today. This specialized technology destroys cancer cells while minimizing damage to surrounding healthy tissues and organs. The Proton Therapy Center at Cincinnati Children’s is one of only two such centers in the United States that is owned by a children’s hospital.

Well-Established Bone Marrow Transplant Program

Our bone marrow transplant team has performed more than 2,000 bone marrow transplants, and helped develop transplant procedures that are now the standard of care in 240 cancer centers throughout North America.

Novel Research

Cincinnati Children’s is one of the largest centers in the United States for pediatric and young adult anticancer drug research. We offer pediatric and adult clinical trials through national research organizations, as well as trials that are only available at Cincinnati Children’s. Our physicians hold leadership positions in national research groups such as the Children's Oncology Group, and bring this expertise to the care of our patients.

Extensive Support Services

These services include social work, occupational therapy, physical therapy, speech therapy, psychology, nutrition, school intervention, therapeutic massage, music therapy, art therapy, child life and more − all integrated into your child’s care plan.

Second-Opinion Service for Patients with High-Risk Cancers

Our team can provide additional clarity and insight when a child is diagnosed with a high-risk or treatment-resistant cancer.

Family-Centered Care

Families are an important part of the care team. We encourage their perspective and input, and take time to help them understand their child’s condition and treatment.

Young Adult Cancer Program

This program provides comprehensive care for cancer patients ages 15-39, addressing their unique medical, emotional and psychosocial concerns.