BS: Pharmacy, Seoul National University, Seoul, South Korea, 2002.
MS: Pharmacy, Seoul National University, Seoul, South Korea, 2004.
PhD: Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, 2009.
Postdoctoral training: Genetics, University of Pennsylvania, Philadelphia, PA, 2012.
Liver cancer; tumor initiation; cell-cell communication; hepatic progenitor cells
General and Thoracic Surgery
Reactive Ductules Are Associated With Angiogenesis and Tumor Cell Proliferation in Pediatric Liver Cancer. Hepatology Communications. 2018; 2:1199-1212.
Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice. Hepatology. 2016; 64:1163-1177.
Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury. Gastroenterology. 2015; 148:192-202.e3.
The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells. Current Topics in Developmental Biology. 2014; 107:269-292.
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes and Development. 2011; 25:1185-1192.
Mechanism of paracrine communications between hepatic progenitor cells and endothelial cells. Cellular Signalling. 2022; 100.
A developmentally prometastatic niche to hepatoblastoma in neonatal liver mediated by the Cxcl1/Cxcr2 axis. Hepatology. 2022; 76:1275-1290.
β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma. Hepatology Communications. 2022; 6:2950-2963.