BS: Pharmacy, Seoul National University, Seoul, South Korea, 2002.
MS: Pharmacy, Seoul National University, Seoul, South Korea, 2004.
PhD: Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, 2009.
Postdoctoral training: Genetics, University of Pennsylvania, Philadelphia, PA, 2012.
Liver cancer; tumor initiation; cell-cell communication; hepatic progenitor cells
General and Thoracic Surgery
Integrated analysis using ToppMiR uncovers altered miRNA- mRNA regulatory networks in pediatric hepatocellular carcinoma-A pilot study.
Whyte, SS; Karns, R; Min, KW; Cho, JH; Lee, S; Lake, C; Bondoc, A; Yoon, JH; Shin, S.
Cellular origins of regenerating liver and hepatocellular carcinoma.
Holczbauer, Á; Wangensteen, KJ; Shin, S.
Adeno-Associated Virus Serotype 8-Mediated Genetic Labeling of Cholangiocytes in the Neonatal Murine Liver.
Lee, S; Zhou, P; Whyte, S; Shin, S.
Reactive Ductules Are Associated With Angiogenesis and Tumor Cell Proliferation in Pediatric Liver Cancer.
Lee, S; Zhou, P; Gupta, A; Shin, S.
Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice.
Shin, S; Wangensteen, KJ; Teta-Bissett, M; Wang, YJ; Mosleh-Shirazi, E; Buza, EL; Greenbaum, LE; Kaestner, KH.
Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury.
Shin, S; Upadhyay, N; Greenbaum, LE; Kaestner, KH.
The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells.
Shin, S; Kaestner, KH.
Current Topics in Developmental Biology.
Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential.
Shin, S; Walton, G; Aoki, R; Brondell, K; Schug, J; Fox, A; Smirnova, O; Dorrell, C; Erker, L; Chu, AS; et al.
Genes and Development.
β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma.
Gulati, R; Johnston, M; Rivas, M; Cast, A; Kumbaji, M; Hanlon, MA; Lee, S; Zhou, P; Lake, C; Schepers, E; et al.
A developmentally prometastatic niche to hepatoblastoma in neonatal liver mediated by the Cxcl1/Cxcr2 axis.
Fan, L; Pan, Q; Yang, W; Koo, SC; Tian, C; Li, L; Lu, M; Brown, A; Ju, B; Easton, J; et al.
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