A photo of Jean Tkach.

Jean Tkach, PhD


  • Medical Physicist, Department of Radiology and Medical Imaging
  • Associate Professor, UC Department of Radiology

About

Biography

Jean Tkach, PhD, received her undergraduate and graduate training in biomedical engineering. She is an MRI physicist by training who has been involved in MRI research since 1985.

Dr. Tkach joined the Cincinnati Children's faculty in the Fall of 2010. Throughout her career, the majority of her effort has been dedicated to the development, implementation, optimization and application of novel MRI acquisition techniques to address clinical as well as more fundamental research questions. The majority of these efforts have been dedicated toward neuroimaging. However, she has also been actively involved in research to advance the fields of cardiac, body and musculoskeletal MR imaging. Although most of Dr. Tkach's work has been directed toward human imaging, she also has been actively involved in multiple animal MR imaging studies.

Dr. Tkach’s research currently focuses on the development and implementation of state of the art MRI acquisition techniques optimized for (and to best address the most relevant clinical needs of) the neonate that exploit new technology being developed for this purpose. Most recently, Dr. Tkach received the Caffey Award for the Best Basic Science Research Paper at the 2011 Annual Meeting of the International Society for Pediatric Radiology.

Dr. Tkach is also is a consultant on the Circulatory System Devices Panel of the Medical Devices Advisory Committee, Center for Devices and Radiological Health, Food and Drug Administration (FDA).

Publications

Patient- and Examination-Related Predictors of 3D MRCP Image Quality in Children. Glenn, A; Trout, AT; Kocaoglu, M; Ata, NA; Crotty, EJ; Tkach, JA; Dillman, JR. American Journal of Roentgenology. 2021.

Magnetic Resonance Imaging Assessment of Pulmonary Vascularity in Infants with Congenital Diaphragmatic Hernia: A Novel Tool for Direct Assessment of Severity of Pulmonary Hypertension and Hypoplasia. Mukthapuram, S; Beebe, J; Tkach, JA; Arya, S; Haberman, B; Peiro, J; Lim, FY; Woods, JC; Kingma, PS. Journal of Pediatrics. 2021; 239:89-94.

Quantitative assessment of velocity and flow using compressed SENSE in children and young adults with adequate acquired temporal resolution. Kocaoglu, M; Pednekar, A; Tkach, JA; Taylor, MD. Journal of Cardiovascular Magnetic Resonance. 2021; 23.

Editorial for "Quality Control of MR Elastography Using Percent Measurable Liver Volume Estimation ". Trout, AT; Tkach, JA. Journal of Magnetic Resonance Imaging. 2021.

Comparison of compressed SENSE and SENSE for quantitative liver MRI in children and young adults. Boyarko, AC; Dillman, JR; Tkach, JA; Pednekar, AS; Trout, AT. Abdominal Radiology. 2021; 46:4567-4575.

Early micro- and macrostructure of sensorimotor tracts and development of cerebral palsy in high risk infants. Chandwani, R; Kline, JE; Harpster, K; Tkach, J; Parikh, NA; Altaye, M; Arnsperger, A; Beiersdorfer, T; Bridgewater, K; Cahill, T; et al. Human Brain Mapping. 2021; 42:4708-4721.

Effects of prenatal opioid exposure on functional networks in infancy. Merhar, SL; Jiang, W; Parikh, NA; Yin, W; Zhou, Z; Tkach, JA; Wang, L; Kline-Fath, BM; He, L; Braimah, A; et al. Developmental Cognitive Neuroscience. 2021; 51.

Editorial for "Hepatic Iron Quantification Using a Free-Breathing 3D Radial Gradient Echo Technique and Validation with a 2D Biopsy-Calibrated R2* Relaxometry Method ". Lindquist, DM; Dillman, JR; Tkach, JA. Journal of Magnetic Resonance Imaging. 2021.

Utilization of 3-T fetal magnetic resonance imaging in clinical practice: a single-institution experience. Nagaraj, UD; Calvo-Garcia, MA; Merrow, AC; Zhang, B; Tkach, JA; Kline-Fath, BM. Pediatric Radiology. 2021; 51:1798-1808.

Prenatal opioid exposure is associated with smaller brain volumes in multiple regions. Merhar, SL; Kline, JE; Braimah, A; Kline-Fath, BM; Tkach, JA; Altaye, M; He, L; Parikh, NA. Pediatric Research. 2021; 90:397-402.