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A photo of Joshua Waxman.

Associate Professor, UC Department of Pediatrics

513-636-7232

513-636-5958

Biography & Affiliation

Research Interests

Cardiac development; heart regeneration; congenital heart defects; molecular signaling pathways; transcription factors; retinoid acid signaling; zebrafish

Academic Affiliation

Associate Professor, UC Department of Pediatrics

Departments

Molecular Cardiovascular Biology, Heart, Developmental Biology

Education

BA: New College, Sarasota, FL,1999.

PhD: University of Washington, Seattle, WA, 2004.

Postdoctoral Fellow: Skirball Institute/NYU School of Medicine, New York, NY, 2004-2009.

Publications

Reiterative mechanisms of retinoic acid signaling during vertebrate heart development. Perl, E; Waxman, JS. Journal of Developmental Biology. 2019; 7:11-11.

HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development. Song, YC; Dohn, TE; Rydeen, AB; Nechiporuk, AV; Waxman, JS. PLoS Genetics. 2019; 15:e1008165-e1008165.

Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish. Skvarca, LB; Han, HI; Espiritu, EB; Missinato, MA; Rochon, ER; McDaniels, MD; Bais, AS; Roman, BL; Waxman, JS; Watkins, SC; et al. DMM Disease Models and Mechanisms. 2019; 12:dmm037390-dmm037390.

In Silico Identification and Experimental Validation of (-)-Muqubilin A, a Marine Norterpene Peroxide, as PPAR/-RXR Agonist and RAR Positive Allosteric Modulator. D'Aniello, E; Iannotti, FA; Falkenberg, LG; Martella, A; Gentile, A; De Maio, F; Ciavatta, ML; Gavagnin, M; Waxman, JS; Di Marzo, V; et al. Marine Drugs. 2019; 17:110-110.

Nr2f-dependent allocation of ventricular cardiomyocyte and pharyngeal muscle progenitors. Dohn, TE; Ravisankar, P; Tirera, FT; Martin, KE; Gafranek, JT; Duong, TB; VanDyke, TL; Touvron, M; Barske, LA; Crump, JG; et al. PLoS Genetics. 2019; 15:e1007962-e1007962.

Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development. Pogoda, H; Riedl-Quinkertz, I; Lohr, H; Waxman, JS; Dale, RM; Topczewski, J; Schulte-Merker, S; Hammerschmidt, M. Development (Cambridge). 2018; 145:dev159418-dev159418.

Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Duong, TB; Ravisankar, P; Song, YC; Gafranek, JT; Rydeen, AB; Dohn, TE; Barske, LA; Crump, JG; Waxman, JS. Developmental Biology. 2018; 434:7-14.

Wnt signaling balances specification of the cardiac and pharyngeal muscle fields. Mandal, A; Holowiecki, A; Song, YC; Waxman, JS. Mechanisms of Development. 2017; 143:32-41.

Retinoic acid and meiosis induction in adult versus embryonic gonads of medaka. Adolfi, MC; Herpin, A; Regensburger, M; Sacquegno, J; Waxman, JS; Schartl, M. Scientific Reports. 2016; 6.

Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. Rydeen, AB; Waxman, JS. PLoS Biology. 2016; 14:e2000504-e2000504.