A photo of Scott Wexelblatt.

Scott L. Wexelblatt, MD


  • Regional Director of Newborn Services, Perinatal Institute
  • Associate Professor, UC Department of Pediatrics

About

Biography

Working in medicine — particularly pediatrics — has long been my dream. At a young age, I was inspired by my own pediatrician, Dr. Marshall “Buzz” Land, who would later become my mentor at the University of Vermont College of Medicine.

Throughout my career, I’ve noticed a need for standardizing and improving care. This insufficiency drew me to research. I have a particular interest in neonatal opioid withdrawal syndrome.

The overall goals of my work are to reduce length of stay, lower the percentage of infants requiring medications and reduce days of opioid treatment.

I was a faculty member and part of the Neonatal Abstinence Syndrome project with the Ohio Perinatal Quality Collaborative (OPQC), which focuses on reducing preterm births and improving newborn and maternal outcomes.

Publications

A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome. van Hoogdalem, MW; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. Pharmacology and Therapeutics. 2022; 234.

Rates of substance and polysubstance use through universal maternal testing at the time of delivery. Smith, BL; Hall, ES; McAllister, JM; Marcotte, MP; Setchell, KD R; Megaraj, V; Jimenez, KL; John Winhusen, T; Wexelblatt, SL. Journal of Perinatology. 2022.

Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome. van Hoogdalem, MW; Johnson, TN; McPhail, BT; Kamatkar, S; Wexelblatt, SL; Ward, LP; Christians, U; Akinbi, HT; Vinks, AA; Mizuno, T. Clinical Pharmacology and Therapeutics. 2022; 111:496-508.

Regional comparison of self-reported late pregnancy cigarette smoking to mass spectrometry analysis. Hall, ES; McAllister, JM; Kelly, EA; Setchell, KD R; Megaraj, V; Jimenez, KL; Nidey, N; Greenberg, JM; Wexelblatt, SL. Journal of Perinatology. 2021; 41:2417-2423.

Quality Improvement Initiative to Improve Healthcare Providers' Attitudes towards Mothers with Opioid Use Disorder. Ford, S; Clarke, L; Walsh, MC; Kuhnell, P; Macaluso, M; Crowley, M; McClead, R; Wexelblatt, S; Lannon, C; Kaplan, HC. Pediatric Quality and Safety. 2021; 6.

Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome. Mizuno, T; McPhail, BT; Kamatkar, S; Wexelblatt, S; Ward, L; Christians, U; Akinbi, HT; Vinks, AA. Clinical Pharmacokinetics. 2021; 60:249-259.

Pharmacotherapy of neonatal opioid withdrawal syndrome: a review of pharmacokinetics and pharmacodynamics. van Hoogdalem, MW; McPhail, BT; Hahn, D; Wexelblatt, SL; Akinbi, HT; Vinks, AA; Mizuno, T. Expert Opinion on Drug Metabolism and Toxicology. 2021; 17:87-103.

Orchestrated Testing of Formula Type to Reduce Length of Stay in Neonatal Abstinence Syndrome. Kaplan, HC; Kuhnell, P; Walsh, MC; Crowley, M; McClead, R; Wexelblatt, S; Ford, S; Provost, LP; Lannon, C; Macaluso, M. Pediatrics. 2020; 146.

Subclinical and Overt Newborn Opioid Exposure: Prevalence and First-Year Healthcare Utilization. Percy, Z; Brokamp, C; McAllister, JM; Ryan, P; Wexelblatt, SL; Hall, ES. Journal of Pediatrics. 2020; 222:52-58.e1.

Medication treatment for opioid use disorder in expectant mothers (MOMs): Design considerations for a pragmatic randomized trial comparing extended-release and daily buprenorphine formulations. Winhusen, T; Lofwall, M; Jones, HE; Wilder, C; Lindblad, R; Schiff, DM; Wexelblatt, S; Merhar, S; Murphy, SM; Greenfield, SF; et al. Controlled Clinical Trials. 2020; 93.

From the Blog


Awareness Needed
BlogSafety and Prevention

Awareness Needed: Babies Born With Drug Withdrawal

By Dr. Scott Wexelblatt10/9/2013

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