Rapamycin is a rather new medicine used to prevent rejection. Small children usually need to take rapamycin twice a day, while older patients just need one dose a day.
How Rapamycin Is Supplied
Rapamune comes in 1 mg and 2 mg tablets or as solution containing 1 mg/1 ml.
- On clinic visit days you will be asked to hold your dose of rapamycin until after blood work is drawn. Your dose will be adjusted based on your rapamycin blood level.
- Please make sure this medicine is always taken with or without food, not sometimes with food and on an empty stomach at other times.
- Take the rapamycin solution with some water or orange juice, but not with grapefruit juice.
Possible Side Effects
Rapamycin can cause several side effects, and regular monitoring during clinic visits, including measurements of rapamycin blood levels, is required. Some of the side effects may require treatment, for example, adding medicines to lower cholesterol or blood pressure.
- Decreased blood cell counts
- High blood pressure
- High blood cholesterol and other blood fats
- Nausea, vomiting, diarrhea, constipation or tummy aches
- Joint pain
- Delayed wound healing
- Mouth sores
- Decrease in sex hormone levels
Rapamune delays wound healing. If your child is having surgery or dental work, call as soon as it is scheduled to taper Rapamune and resume Prograf. After your child has healed from surgery, he will be converted back to Rapamune.