Troutman Lab

Publications

Felton, JM; Edsall, LE; Troutman, TD; Mack, L; Kotliar, M; Morgenstern, NB-B; Psaila, AM; Rochman, M; Klingler, AM; Osswald, GA; Barski, A; Quinlan, KGR; Weirauch, MT; Rothenberg, ME. Epigenetic and transcriptional programming of murine eosinophils in the esophagus. Nature Communications. 2025; 16(1):10454.

Weinhaus, B; Homan, S; Kincaid, M; Tadwalkar, A; Gu, X; Kumar, S; Slaughter, A; Zhang, J; Wu, Q; Kofron, JM; Troutman, TD; Defalco, T; Lucas, D. Differential regulation of fetal bone marrow and liver hematopoiesis by yolk-sac-derived myeloid cells. Nature Communications. 2025; 16(1):4427.

Dunn, JLM; Szep, A; Gonzalez Galan, E; Zhang, S; Marlman, J; Caldwell, JM; Troutman, TD; Rothenberg, ME. Eosinophil specialization is regulated by exposure to the esophageal epithelial microenvironment. Journal of Leukocyte Biology. 2024; 116(5):1007-1020.

Ganguly, S; Rosenthal, SB; Ishizuka, K; Troutman, TD; Rohm, TV; Khader, N; Aleman-Muench, G; Sano, Y; Archilei, S; Soroosh, P; Loomba, R; Glass, CK; Brenner, DA; Dhar, D. Lipid-associated macrophages' promotion of fibrosis resolution during MASH regression requires TREM2. Proceedings of the National Academy of Sciences of the United States of America. 2024; 121(35):e2405746121.

Abe, Y; Kofman, ER; Ouyang, Z; Cruz-Becerra, G; Spann, NJ; Seidman, JS; Troutman, TD; Stender, JD; Taylor, H; Fan, W; Evans, RM; Kadonaga, JT; Rosenfeld, MG; Glass, CK. A TLR4/TRAF6-dependent signaling pathway mediates NCoR coactivator complex formation for inflammatory gene activation. Proceedings of the National Academy of Sciences of the United States of America. 2024; 121(2):e2316104121.

Proper, SP; Dwyer, AT; Appiagyei, A; Felton, JM; Ben-Baruch Morgenstern, N; Marlman, JM; Kotliar, M; Barski, A; Troutman, TD; Rothenberg, ME; Mersha, TB; Azouz, NP. Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis. Frontiers in Allergy. 2024; 5:1323405.

Shao, T-Y; Jiang, TT; Stevens, J; Russi, AE; Troutman, TD; Bernieh, A; Pham, G; Erickson, JJ; Eshleman, EM; Alenghat, T; Weaver, CT; Haslam, DB; Deshmukh, H; Way, SS. Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation. Cell reports. 2023; 42(11):113323.

Bennett, H; Troutman, TD; Zhou, E; Spann, NJ; Link, VM; Seidman, JS; Nickl, CK; Abe, Y; Sakai, M; Pasillas, MP; Marlman, JM; Guzman, C; Hosseini, M; Schnabl, B; Glass, CK. Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes. Nature Immunology. 2023; 24(11):1825-1838.

Kudira, R; Pasula, S; Vom Hofe, AY; Pfuhler, L; Singh, M; Kasten, J; Bernieh, A; Kostrub, C; Vig, P; Troutman, T; Miethke, A. FRI-350 Genetic predisposition for liver inflammation and response to anti-cholestatic therapy in experimental sclerosing cholangitis. Journal of Hepatology. 2023; 78:s417-s418.

Arimoto, K-I; Miyauchi, S; Troutman, TD; Zhang, Y; Liu, M; Stoner, SA; Davis, AG; Fan, J-B; Huang, Y-J; Yan, M; Glass, CK; Zhang, D-E. Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nature Communications. 2023; 14(1):251.

Underwood, B; Troutman, TD; Schwartz, JT. Breaking down the complex pathophysiology of eosinophilic esophagitis. Annals of Allergy, Asthma and Immunology. 2023; 130(1):28-39.

Bennett, H; Troutman, TD; Zhou, E; Spann, NJ; Link, VM; Seidman, JS; Nickl, CK; Abe, Y; Sakai, M; Pasillas, MP; Marlman, JM; Guzman, C; Hosseini, M; Schnabl, B; Glass, CK. Systematic analysis of transcriptional and epigenetic effects of genetic variation in Kupffer cells enables discrimination of cell intrinsic and environment-dependent mechanisms. bioRxiv. 2022; 2022.09.22.509046.

Troutman, TD; Kofman, E; Glass, CK. Exploiting dynamic enhancer landscapes to decode macrophage and microglia phenotypes in health and disease. Molecular Cell. 2021; 81(19):3888-3903.

Rosenthal, SB; Liu, X; Ganguly, S; Dhar, D; Pasillas, MP; Ricciardelli, E; Li, RZ; Troutman, TD; Kisseleva, T; Glass, CK; Brenner, DA. Heterogeneity of HSCs in a Mouse Model of NASH. Hepatology. 2021; 74(2):667-685.

Troutman, TD; Bennett, H; Sakai, M; Seidman, JS; Heinz, S; Glass, CK. Purification of mouse hepatic non-parenchymal cells or nuclei for use in ChIP-seq and other next-generation sequencing approaches. STAR Protocols. 2021; 2(1):100363.

Texari, L; Spann, NJ; Troutman, TD; Sakai, M; Seidman, JS; Heinz, S. An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells. STAR Protocols. 2021; 2(1):100358.