Pain affects individuals from birth to old age, and can span time frames from seconds to years. It is a problem that transcends multiple research approaches, clinical domains, and organ systems. Cincinnati Children’s is home to internationally recognized pain research scientists, and world-class pain research and treatment programs.

The Consortium for Understanding Pediatric Pain (CUPP) at Cincinnati Children’s integrates this world-class pain research and expertise across multiple groups to amplify synergies and collaborations in research, training, and patient care.

CUPP is a unique multi-divisional collaboration of laboratories representing the many different domains of pain research, training, and treatment. We weave world-class clinical care with ground-breaking basic science and clinical research, seamlessly integrating the understanding and treatment of pediatric pain.

CUPP laboratories reside in the Department of Anesthesiology, Division of Behavioral Medicine and Clinical Psychology, Division of Neurology, and Division of Sports Medicine. Their research is supported with research and clinical facilities including the Imaging Research Center, Pediatric Neuroimaging Research Consortium, Pain Management Program (outpatient), Functional Independence Restoration Program (inpatient), and the Headache Center.

Our Mission:

Foster comprehensive multidisciplinary collaborations to examine basic mechanisms, clinical presentation and management of pediatric pain, develop new insights into basic mechanisms of pain and translate them into new treatments

Our Goals:

  • Understand the mechanisms that generate pain in children across a broad variety of etiologies and translate this knowledge into better treatments.
  • Better understand pain and its impact on the individual child in order to provide personalized treatment.

We will achieve these goals by pursuing the following aims:

  • Collaborate across CCHMC laboratories representing different domains of pain research, training, and treatment
  • Accelerate the translation of basic science discoveries into clinical care
  • Standardization of data acquisition across different domains.
  • Train basic and clinical researchers and will help them grow the skills needed to maintain the future strength.
  • Assure data and infrastructure coordination across all domains of pain research, training, and treatment.