Biagini Lab

Publications

Martin, LJ; He, H; Spagna, D; Jenkins, S; Grashel, B; Chang, WC; Williams, L; Hammonds, M; Johansson, E; Sherenian, MG; Biagini, JM; Satish, L; Kottyan, L; Khurana Hershey, GK. Genome-wide cross-trait analysis of heterogeneous outcomes in early life atopic dermatitis. Pediatric Allergy and Immunology. 2025; 36(12):e70253.

Biagini, JM; He, H; Chang, W-C; Williams, L; Hammonds, M; Martin, LJ; Khurana Hershey, GK. Socioeconomic deprivation performs equally to race in the Pediatric Asthma Risk Score. Pediatric Allergy and Immunology. 2025; 36(12):e70263.

Gill, KK; Moore, C; Nwogu, O; Kroner, JW; Chang, W-C; Burkle, J; Virolainen, SJ; Stevens, ML; Baatyrbek, A; Miraldi, ER; Martin, LJ; Andorf, S; Khurana Hershey, GK; Roskin, KM. B-Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization. Allergy. European Journal of Allergy and Clinical Immunology. 2025.

Sherenian, MG; Chang, WC; Almasri, C; Biagini, JM; Togias, A; Khurana Hershey, GK. Objective sensitization algorithm validates parental report of food allergy in children. Journal of Allergy and Clinical Immunology: Global. 2025; 4(4):100512.

Castro-Rodriguez, JA; Wolters, AAB; Rodriguez-Martinez, CE; Biagini, JM; Celedón, JC; Custovic, A; Koppelman, GH; Phipatanakal, W; Saglani, S; Forno, E. Risk Factors and Mechanisms Leading to Preschool Recurrent Wheeze and Asthma. Journal of Allergy and Clinical Immunology: In Practice. 2025; 13(10):2537-2551.

Phelan, KJ; Roskin, KM; Burkle, JW; Chang, W-C; Martin, LJ; Biagini, JM; Satish, L; Haslam, DB; Spagna, D; Jenkins, S; Visness, CM; Altman, MC; Gern, JE; Khurana Hershey, GK. Early-life wheeze trajectories are associated with distinct asthma transcriptomes later in life. Journal of Allergy and Clinical Immunology. 2025; 156(3):640-650.

Sitarik, AR; Eapen, AA; Biagini, JM; Jackson, DJ; Joseph, CLM; Kim, H; Martin, LJ; Rivera-Spoljaric, K; Schauberger, EM; Wegienka, G; Singh, S; Wright, AL; Gern, JE; Singh, AM. Phenotypes of Atopic Dermatitis and Development of Allergic Diseases. JAMA Network Open. 2025; 8(6):e2515094.

Dahal, A; Chang, WC; Johansson, E; Grashel, B; Morgan, D; Williams, L; Hammonds, M; Sachdeva, S; Spagna, D; Satish, L; Biagini, JM; Martin, LJ; Haslam, DB; Ollberding, NJ; Khurana Hershey, GK. Skin Staphylococcus aureus detection and relationship to atopic dermatitis outcomes using culture and metagenomic sequencing. Scientific Reports. 2025; 15(1):17606.

Chang, WC; Burkle, JW; Williams, LR; Hammonds, MK; Weheba, FA; Satish, L; Martin, LJ; Guilbert, TW; Sherenian, MG; Mersha, TB; Biagini, JM; Khurana Hershey, GK. Race-Specific and Race-Neutral Equations for Lung Function and Asthma Diagnosis in Black Children. JAMA Network Open. 2025; 8(2):e2462176.

Gautam, Y; Satish, L; Ramirez, S; Grashel, B; Biagini, JM; Martin, LJ; Rothenberg, ME; Khurana Hershey, GK; Mersha, TB. Joint genotype and ancestry analysis identify novel loci associated with atopic dermatitis in African American population. HGG Advances. 2024; 5(4):100350.

Ochayon, DE; Devore, SB; Chang, W-C; Krishnamurthy, D; Seelamneni, H; Grashel, B; Spagna, D; Andorf, S; Martin, LJ; Biagini, JM; Waggoner, SN; Khurana Hershey, GK. Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early childhood severe atopic dermatitis. Science immunology. 2024; 9(92):eadd3085.

Devore, SB; Schuetz, M; Alvey, L; Lujan, H; Ochayon, DE; Williams, L; Chang, WC; Filuta, A; Ruff, B; Kothari, A; Keles, S; Milner, JD; Supp, DM; Khurana Hershey, GK. Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease. Cell reports. 2024; 43(8):114589.

Aris, IM; Lin, P-ID; Wu, AJ; Dabelea, D; Lester, BM; Wright, RJ; Karagas, MR; Kerver, JM; Dunlop, AL; Joseph, CL; Amutah-Onukagha, N; Hacker, MR; James-Todd, T; Oken, E. Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study. American Journal of Clinical Nutrition. 2024; 119(5):1216-1226.

Virolainen, SJ; Satish, L; Biagini, JM; Chaib, H; Chang, WC; Dexheimer, PJ; Dixon, MR; Dunn, K; Fletcher, D; Forney, C; Shook, M; Weirauch, MT; Khurana Hershey, GK; Kottyan, LC. Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort. JCI Insight. 2024; 9(9).

Sherenian, M; Biagini, JM; Ryan, P; Khurana Hershey, GK. What allergists/immunologists can do to limit the effects of air pollution on asthma and allergies. Annals of Allergy, Asthma and Immunology. 2024; 132(4):421-422.

Filuta, AL; Amezcua, P; Ruff, BP; Biagini, JM; Kroner, J; He, H; Brandt, EB; Martin, LJ; Palumbo, JS; Khurana Hershey, GK; Sherenian, MG. The key roles of thrombin and fibrinogen in human infant and mice atopic dermatitis models. Allergy. European Journal of Allergy and Clinical Immunology. 2024; 79(1):239-242.

Dahal, A; Chang, WC; Almasri, C; Johansson, E; Hurd, M; Velasquez, V; Grashel, B; Spagna, D; Jenkins, S; Morgan, D; Satish, L; Martin, LJ; Biagini, JM; Khurana Hershey, GK. Temporal relationships between Staphylococcus aureus colonization, filaggrin expression, and pediatric atopic dermatitis. Allergy. European Journal of Allergy and Clinical Immunology. 2024; 79(1):104-115.

Biagini, JM; Martin, LJ; He, H; Bacharier, LB; Gebretsadik, T; Hartert, TV; Jackson, DJ; Kim, H; Miller, RL; Rivera-Spoljaric, K; Johnson, CC; Wright, AL; Gern, JE; Khurana Hershey, GK. Performance of the Pediatric Asthma Risk Score across Diverse Populations. NEJM Evid. 2023; 2(10):EVIDoa2300026.

Phelan, KJ; Dill-Mcfarland, KA; Kothari, A; Segnitz, RM; Burkle, J; Grashel, B; Jenkins, S; Spagna, D; Martin, LJ; Haslam, DB; Jackson, DJ; Mersha, TB; Altman, MC; Khurana Hershey, GK. Airway transcriptome networks identify susceptibility to frequent asthma exacerbations in children. Journal of Allergy and Clinical Immunology. 2023; 152(1):73-83.

Pennington, J; Rasnick, E; Martin, LJ; Biagini, JM; Mersha, TB; Parsons, A; Khurana Hershey, GK; Ryan, P; Brokamp, C. Racial Fairness in Precision Medicine: Pediatric Asthma Prediction Algorithms. American Journal of Health Promotion. 2023; 37(2):239-242.

Sitarik, A; Biagini, J; Eapen, A; Jackson, D; Joseph, C; Kim, H; Martin, L; Rivera-Spoljaric, K; Schauberger, E; Wegienka, G; Gern, J; Singh, AM. Longitudinal Characterization of Atopic Dermatitis Phenotypes in The Children's Respiratory and Environmental Workgroup (CREW) Birth Cohort Consortium. Journal of Allergy and Clinical Immunology. 2023; 151(2):ab145.

Eapen, A; Sitarik, A; Biagini, J; Jackson, D; Joseph, C; Kim, H; Martin, L; Rivera-Spoljaric, K; Schauberger, E; Wegienka, G; Gern, J; Singh, AM. Longitudinal assessment of Allergic Outcomes and Atopic Dermatitis Phenotypes in The Children's Respiratory and Environmental Workgroup (CREW) Birth Cohort Consortium. Journal of Allergy and Clinical Immunology. 2023; 151(2):ab146.

Namjou, B; Lape, M; Malolepsza, E; Devore, SB; Weirauch, MT; Dikilitas, O; Jarvik, GP; Kiryluk, K; Kullo, IJ; Liu, C; Biagini, JM; Khurana Hershey, GK; Martin, LJ; Kottyan, L. Multiancestral polygenic risk score for pediatric asthma. Journal of Allergy and Clinical Immunology. 2022; 150(5):1086-1096.

Zanobetti, A; Ryan, PH; Coull, B; Brokamp, C; Datta, S; Blossom, J; Lothrop, N; Miller, RL; Beamer, PI; Visness, CM; Martinez, FD; Seroogy, CM; Gern, JE; Gold, DR. Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium. JAMA pediatrics. 2022; 176(8):759-767.

Macdonald, M; Chang, W-C; Martin, LJ; Khurana Hershey, GK; Biagini, JM. The Pediatric Asthma Risk Score: More does not mean better. Annals of Allergy, Asthma and Immunology. 2022; 128(6):729-730.

Biagini, JM; Kroner, JW; Baatyrbek Kyzy, A; Gonzales, A; He, H; Stevens, M; Grashel, B; Spagna, D; Paul, S; Patel, R; Bucci, A; Sherenian, MG; Murrison, LB; Martin, LJ; Khurana Hershey, GK. Longitudinal atopic dermatitis endotypes: An atopic march paradigm that includes Black children. Journal of Allergy and Clinical Immunology. 2022; 149(5):1702-1710.e4.

Guilbert, TW; Biagini, JM; Ramsey, RR; Keidel, K; Curtsinger, K; Kroner, JW; Durrani, SR; Stevens, M; Pilipenko, V; Martin, LJ; Kercsmar, CM; Hommel, K; Hershey, GKK. Treatment by biomarker-informed endotype vs guideline care in children with difficult-to-treat asthma. Annals of Allergy, Asthma and Immunology. 2022; 128(5):535-543.e6.

Johansson, E; Biagini, JM; Martin, LJ; He, H; Kroner, JW; Almasri, C; Velasquez, V; Sonzogni, M; Devore, SB; Spagna, D; Grashel, B; Hershey, GKK. Vitamin D, skin filaggrin, allergic sensitization, and race. Annals of Allergy, Asthma and Immunology. 2022; 128(4):399-407.e3.

Mcalees, JW; Baker, T; Houshel, L; Mcknight, C; Lindsley, A; Strait, RT; Zhang, X; Cannata, A; Biagini, JM; Butsch Kovacic, M; Lewkowich, IP. Increased nasal epithelial cell responsiveness to IL-17A in paediatric asthmatics with low blood neutrophil count, low traffic-related air pollution exposure and good asthma control. Clinical and Experimental Allergy. 2022; 52(4):569-573.

Devore, SB; Stevens, ML; He, H; Biagini, JM; Kroner, JW; Martin, LJ; Khurana Hershey, GK. Novel role for caspase recruitment domain family member 14 and its genetic variant rs11652075 in skin filaggrin homeostasis. Journal of Allergy and Clinical Immunology. 2022; 149(2):708-717.

Murrison, LB; Ren, X; Preusse, K; He, H; Kroner, J; Chen, X; Jenkins, S; Johansson, E; Biagini, JM; Weirauch, MT; Kopan, R; Martin, LJ; Khurana Hershey, GK. TSLP disease-associated genetic variants combined with airway TSLP expression influence asthma risk. Journal of Allergy and Clinical Immunology. 2022; 149(1):79-88.

Johnson, CC; Havstad, SL; Ownby, DR; Joseph, CLM; Sitarik, AR; Biagini Myers, J; Gebretsadik, T; Hartert, TV; Khurana Hershey, GK; Jackson, DJ; Miller, RL; Seroogy, CM; Wright, AL; Gern, JE. Pediatric asthma incidence rates in the United States from 1980 to 2017. Journal of Allergy and Clinical Immunology. 2021; 148(5):1270-1280.

Johansson, E; Martin, LJ; He, H; Chen, X; Weirauch, MT; Kroner, JW; Khurana Hershey, GK; Biagini, JM. Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity. Clinical and Experimental Allergy. 2021; 51(6):801-810.

Zhu, T; Zhang, X; Chen, X; Brown, AP; Weirauch, MT; Guilbert, TW; Khurana Hershey, GK; Biagini, JM; Ji, H. Nasal DNA methylation differentiates severe from non-severe asthma in African-American children. Allergy. European Journal of Allergy and Clinical Immunology. 2021; 76(6):1836-1845.

Sherenian, MG; Kothari, A; Biagini, JM; Kroner, JW; Baatyrbek Kyzy, A; Johannson, E; Atluri, G; He, H; Martin, LJ; Khurana Hershey, GK. Sensitization to peanut, egg or pets is associated with skin barrier dysfunction in children with atopic dermatitis. Clinical and Experimental Allergy. 2021; 51(5):666-673.

Brooks, CC; Martin, LJ; Pilipenko, V; He, H; Lemasters, GK; Lockey, JE; Bernstein, DI; Ryan, PH; Khurana Hershey, GK; Biagini Myers, JM. NAT1 genetic variation increases asthma risk in children with secondhand smoke exposure. Journal of Asthma. 2021; 58(3):284-292.

Ryan, PH; Brokamp, C; Blossom, J; Lothrop, N; Miller, RL; Beamer, PI; Visness, CM; Zanobetti, A; Andrews, H; Bacharier, LB; Martinez, FD; Seroogy, CM; Gern, JE; Gold, DR. A distributed geospatial approach to describe community characteristics for multisite studies. Journal of Clinical and Translational Science. 2021; 5(1):e86.

Gonzalez, T; Stevens, ML; Baatyrbek Kyzy, A; Alarcon, R; He, H; Kroner, JW; Spagna, D; Grashel, B; Sidler, E; Martin, LJ; Biagini Myers, JM; Khurana Hershey, GK; Herr, AB. Biofilm propensity of Staphylococcus aureus skin isolates is associated with increased atopic dermatitis severity and barrier dysfunction in the MPAACH pediatric cohort. Allergy. European Journal of Allergy and Clinical Immunology. 2021; 76(1):302-313.